Histological quantitation of brain injury using whole slide imaging: A pilot validation study in mice

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Chen, Zhenzhou ^a,e   Shin, Dmitriy ^a   Chen, Shanyan ^a,b   Mikhail, Kovalenko ^a   Hadass, Orr ^a   Tomlison, Brittany N ^a   Korkin, Dmitry ^c   Shyu, Chi Ren ^c   Cui, Jiankun ^a   Anthony, Douglas C ^a,d   Gu, Zezong ^a  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c University of Missouri   (United States)

^d BROWN UNIVERSITY   (United States)

^e SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; BRAIN INJURY; CELL DENSITY; CEREBROVASCULAR ACCIDENT; CLASSIFICATION ALGORITHM; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIAGNOSTIC IMAGING EQUIPMENT; EVOLUTIONARY ALGORITHM; HIGH THROUGHPUT SCREENING; HISTOPATHOLOGY; IMAGE ANALYSIS; IMAGE PROCESSING; IMMUNOREACTIVITY; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL DEGENERATION; NEUROIMAGING; NONHUMAN; PILOT STUDY; QUANTITATIVE ANALYSIS; TRAUMATIC BRAIN INJURY; VALIDATION PROCESS; WHOLE SLIDE IMAGING; WHOLE SLIDE SCANNER;

ALGORITHMS; ANIMALS; AUTOMATION; BRAIN INJURIES; CELL COUNT; CEREBRAL CORTEX; CEREBRAL HEMORRHAGE; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; NECROSIS; NERVE DEGENERATION; NEUROIMAGING; PILOT PROJECTS; SILVER STAINING;

EID: 84898652964     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092133     Document Type: Article

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