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Volumn 9, Issue 1, 2014, Pages

EGFR, HER-2 and KRAS in canine gastric epithelial tumors: A potential human model?

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; K RAS PROTEIN; PRIMER DNA;

EID: 84898637547     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085388     Document Type: Article
Times cited : (33)

References (43)
  • 1
    • 54149113866 scopus 로고    scopus 로고
    • Cancer of the gastrointestinal tract
    • Withrow SJ, Wail DM, 4th edition. St. Louis, Missouri: Elsevier Saunders
    • Withrow SJ (2007) Cancer of the gastrointestinal tract. In: Withrow SJ, Wail DM. Withrow and MacEwen's Small Animal Clinical Oncology. 4th edition. St. Louis, Missouri: Elsevier Saunders. 480-482.
    • (2007) Withrow and MacEwen's Small Animal Clinical Oncology , pp. 480-482
    • Withrow, S.J.1
  • 2
    • 0036130963 scopus 로고    scopus 로고
    • Canine gastric adenocarcinoma and leiomyosarcoma: A retrospective study of 21 cases (1986-1999) and literature review
    • Swann HM, Holt DE (2002) Canine gastric adenocarcinoma and leiomyosarcoma: a retrospective study of 21 cases (19 (Pubitemid 34232794)
    • (2002) Journal of the American Animal Hospital Association , vol.38 , Issue.2 , pp. 157-164
    • Swann, H.M.1    Holt, D.E.2
  • 6
    • 81755161341 scopus 로고    scopus 로고
    • HER2 testing in gastric and gastroesophageal junction cancers: A new therapeutic target and diagnostic challenge
    • Hicks DG, Whitney-Miller C (2011) HER2 testing in gastric and gastroesophageal junction cancers: a new therapeutic target and diagnostic challenge. Appl Immunohistochem Mol Morphol 19:506-508.
    • (2011) Appl Immunohistochem Mol Morphol , vol.19 , pp. 506-508
    • Hicks, D.G.1    Whitney-Miller, C.2
  • 7
    • 79958854150 scopus 로고    scopus 로고
    • How will human epidermal growth factor receptor 2-neu data impact clinical management of gastric cancer?
    • Lorenzen S, Lordick F (2011) How will human epidermal growth factor receptor 2-neu data impact clinical management of gastric cancer? Curr Opin Oncol 23:396-402.
    • (2011) Curr Opin Oncol , vol.23 , pp. 396-402
    • Lorenzen, S.1    Lordick, F.2
  • 8
    • 1542329005 scopus 로고    scopus 로고
    • The erbB family: Targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors
    • DOI 10.1146/annurev.med.55.091902.104433
    • Rowinsky EK (2004) The erbB family: target for Therapeutic Develoment Against Cancer and Therapeutic Strategies Using Monoclonal Antibodies and Tyrosine Kinase Inhibitors. Annu Rev Med 55:433-457. (Pubitemid 38316736)
    • (2004) Annual Review of Medicine , vol.55 , pp. 433-457
    • Rowinsky, E.K.1
  • 9
    • 50849123421 scopus 로고    scopus 로고
    • HER2 in gastric cancer: A new prognostic factor and a novel therapeutic target
    • Gravalos C, Jimeno A (2008) HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target. Ann Oncol 19:1523-1529.
    • (2008) Ann Oncol , vol.19 , pp. 1523-1529
    • Gravalos, C.1    Jimeno, A.2
  • 10
    • 77954217471 scopus 로고    scopus 로고
    • Trastuzumab ingastric cancer
    • Okines AFC, Cunningham D (2010) Trastuzumab ingastric cancer. EurJCancer 46:1949-1959.
    • (2010) EurJCancer , vol.46 , pp. 1949-1959
    • Okines, A.F.C.1    Cunningham, D.2
  • 11
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, et al. (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 376:687-697.
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5
  • 12
    • 81555209827 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor 2 testing in gastric carcinoma: Issues related to heterogeneity in biopsies and resections
    • Lee S, De Boer WB, Fermoyle S, Platten M, Kumarasinghe MP (2011) Human epidermal growth factor receptor 2 testing in gastric carcinoma: issues related to heterogeneity in biopsies and resections. Histopathology 59:832-840.
    • (2011) Histopathology , vol.59 , pp. 832-840
    • Lee, S.1    De Boer, W.B.2    Fermoyle, S.3    Platten, M.4    Kumarasinghe, M.P.5
  • 13
    • 0028907863 scopus 로고
    • Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancer
    • Tokunaga A, Onda M, Okuda T, Teramoto T, Fujita I, et al. (1995) Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancer. Cancer 75:1418-1425.
    • (1995) Cancer , vol.75 , pp. 1418-1425
    • Tokunaga, A.1    Onda, M.2    Okuda, T.3    Teramoto, T.4    Fujita, I.5
  • 15
    • 70349937924 scopus 로고    scopus 로고
    • Phase II study study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study)
    • Pinto C, Di Fabio F, Barone C, Siena S, Falcone A, et al. (2009) Phase II study study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study). Br J Cancer 101:1261-1268.
    • (2009) Br J Cancer , vol.101 , pp. 1261-1268
    • Pinto, C.1    Di Fabio, F.2    Barone, C.3    Siena, S.4    Falcone, A.5
  • 16
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, et al. (2008) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351:337-345.
    • (2008) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3    Khayat, D.4    Bleiberg, H.5
  • 17
    • 84880531371 scopus 로고    scopus 로고
    • Direct sequencing is a reliable assay with good clinical applicability for KRAS mutation testing in colorectal cancer
    • Wang J, Yang H, Shen Y, Wang S, Lin D, et al. (2013) Direct sequencing is a reliable assay with good clinical applicability for KRAS mutation testing in colorectal cancer. Cancer Biomark 13:89-97.
    • (2013) Cancer Biomark , vol.13 , pp. 89-97
    • Wang, J.1    Yang, H.2    Shen, Y.3    Wang, S.4    Lin, D.5
  • 18
    • 70350270341 scopus 로고    scopus 로고
    • Immunohistochemical expression of Epidermal Growth Factor Receptor (EGFR) in canine mammary tissues
    • Gama A, Gärtner F, Alves A, Schmitt F (2009) Immunohistochemical expression of Epidermal Growth Factor Receptor (EGFR) in canine mammary tissues. Res Vet Sci 87:432-437.
    • (2009) Res Vet Sci , vol.87 , pp. 432-437
    • Gama, A.1    Gärtner, F.2    Alves, A.3    Schmitt, F.4
  • 19
    • 65749111222 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumors
    • Shiomitsu K, Johnson CL, Malarkey DE, Pruitt AF, Thrall DE (2009) Expression of epidermal growth factor receptor and vascular endothelial growth factor in malignant canine epithelial nasal tumors. Vet Comp Oncol 7:106-114.
    • (2009) Vet Comp Oncol , vol.7 , pp. 106-114
    • Shiomitsu, K.1    Johnson, C.L.2    Malarkey, D.E.3    Pruitt, A.F.4    Thrall, D.E.5
  • 20
    • 79956044486 scopus 로고    scopus 로고
    • Epidermal growth factor receptor as a therapeutic target in veterinary oncology
    • Bergkvist GT, Yool DA (2010) Epidermal growth factor receptor as a therapeutic target in veterinary oncology. Vet Comp Oncol 9:81-94.
    • (2010) Vet Comp Oncol , vol.9 , pp. 81-94
    • Bergkvist, G.T.1    Yool, D.A.2
  • 21
    • 77953616455 scopus 로고    scopus 로고
    • Spontaneous canine gliomas: Overexpression of EGFR, PDGFRalpha and IGFBP2 demonstrated by tissue microarray immunophenotyping
    • Higgins RJ, Dickinson PJ, Lecouteur RA, Bollen AW, Wang H, et al. (2010) Spontaneous canine gliomas: overexpression of EGFR, PDGFRalpha and IGFBP2 demonstrated by tissue microarray immunophenotyping. J Neurooncol 98:49-55.
    • (2010) J Neurooncol , vol.98 , pp. 49-55
    • Higgins, R.J.1    Dickinson, P.J.2    Lecouteur, R.A.3    Bollen, A.W.4    Wang, H.5
  • 22
    • 84905374202 scopus 로고    scopus 로고
    • EGFR overexpression in canine primary lung cancer: Pathogenetic implications and impact on survival
    • In press
    • Sabattini S, Mancini FR, Marconato L, Bacci B, Rossi F, et al. (2012) EGFR overexpression in canine primary lung cancer: pathogenetic implications and impact on survival. Vet Comp Oncol In press.
    • (2012) Vet Comp Oncol
    • Sabattini, S.1    Mancini, F.R.2    Marconato, L.3    Bacci, B.4    Rossi, F.5
  • 23
    • 0042825448 scopus 로고    scopus 로고
    • Oncogene HER-2 in canine mammary gland carcinomas: An immunohistochemical and chromogenic in situ hybridization study
    • DOI 10.1023/A:1024929730165
    • Martin De Las Mulas J, Ordá S, Millán Y, Fernandez-Soria V, Ramón Cajal S (2003) Oncogene HER-2 in canine mammary gland carcinomas: an immunohistochemical and chromogenic in situ hybridization study. Breast Cancer Res Treat 80:363-367. (Pubitemid 37046761)
    • (2003) Breast Cancer Research and Treatment , vol.80 , Issue.3 , pp. 363-367
    • Martin De Las Mulas, J.1    Ordas, J.2    Millan, Y.3    Fernandez-Soria, V.4    Ramon Y Cajal, S.5
  • 24
    • 60549114710 scopus 로고    scopus 로고
    • Increased survival in dogs with malignant mammary tumours overexpressing HER-2 protein and detection of a silent single nucleotide polymorphism in the canine HER-2 gene
    • Hsu WL, Huang HM, Liao JW, Wong ML, Chang SC (2009) Increased survival in dogs with malignant mammary tumours overexpressing HER-2 protein and detection of a silent single nucleotide polymorphism in the canine HER-2 gene. Vet J 180:116-123.
    • (2009) Vet J , vol.180 , pp. 116-123
    • Hsu, W.L.1    Huang, H.M.2    Liao, J.W.3    Wong, M.L.4    Chang, S.C.5
  • 25
    • 84873745200 scopus 로고    scopus 로고
    • HER-2 expression in canine morphologically normal, hyperplastic and neoplastic mammary tissues and its correlation with the clinical outcome
    • Ressel L, Puleio R, Loria GR, Vannozzi I, Millanta F, et al. (2013) HER-2 expression in canine morphologically normal, hyperplastic and neoplastic mammary tissues and its correlation with the clinical outcome. Res Vet Sci 94:299-305.
    • (2013) Res Vet Sci , vol.94 , pp. 299-305
    • Ressel, L.1    Puleio, R.2    Loria, G.R.3    Vannozzi, I.4    Millanta, F.5
  • 26
    • 84858330284 scopus 로고    scopus 로고
    • Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting
    • Singer J, Weichselbaumer M, Stockner T, Mechtcheriakova D, Sobanov Y, et al. (2012) Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting. Mol Immunol 50:200-209.
    • (2012) Mol Immunol , vol.50 , pp. 200-209
    • Singer, J.1    Weichselbaumer, M.2    Stockner, T.3    Mechtcheriakova, D.4    Sobanov, Y.5
  • 28
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification
    • Lauren P (1965) The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 64:31-49.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 29
    • 78650993111 scopus 로고    scopus 로고
    • 7th edition of the AJCC cancer staging manual: Stomach
    • Washington K (2010) 7th Edition of the AJCC Cancer Staging Manual: Stomach. Ann Surg Oncol 17:3077-3079.
    • (2010) Ann Surg Oncol , vol.17 , pp. 3077-3079
    • Washington, K.1
  • 30
    • 77951887041 scopus 로고    scopus 로고
    • Molecular-based tumor subtypes of canine mammary carcinomas assessed by immunohistochemistry
    • Sassi F, Benazzi C, Castellani G, Sarli G (2010) Molecular-based tumor subtypes of canine mammary carcinomas assessed by immunohistochemistry. BMC Vet Res 6:5.
    • (2010) BMC Vet Res , vol.6 , pp. 5
    • Sassi, F.1    Benazzi, C.2    Castellani, G.3    Sarli, G.4
  • 31
    • 79960792681 scopus 로고    scopus 로고
    • Assessment of ERBB2 and EGFR gene amplification and protein expression in gastric carcinoma by immunohistochemistry and fluorescence in situ hybridization
    • Wang YK, Gao CF, Yun T, Chen Z, Zhang XW, et al. (2011) Assessment of ERBB2 and EGFR gene amplification and protein expression in gastric carcinoma by immunohistochemistry and fluorescence in situ hybridization. Mol Cytogenet 4:14.
    • (2011) Mol Cytogenet , vol.4 , pp. 14
    • Wang, Y.K.1    Gao, C.F.2    Yun, T.3    Chen, Z.4    Zhang, X.W.5
  • 33
    • 0016606069 scopus 로고
    • Gastric neoplasms in the dog: A report of 20 cases
    • Sautter JH, Hanlon GF (1975) Gastric neoplasms in the dog: a report of 20 cases. J Am Vet Med Assoc 166:691-696.
    • (1975) J Am Vet Med Assoc , vol.166 , pp. 691-696
    • Sautter, J.H.1    Hanlon, G.F.2
  • 34
    • 84985408354 scopus 로고
    • Gastric carcinoma in the dog: A clinicopathological study of 11 cases
    • Fonda D, Gualtieri M, Scanziani E (1989) Gastric carcinoma in the dog: a clinicopathological study of 11 cases. J Small Anim Pract 30:353-360.
    • (1989) J Small Anim Pract , vol.30 , pp. 353-360
    • Fonda, D.1    Gualtieri, M.2    Scanziani, E.3
  • 35
    • 33646002797 scopus 로고    scopus 로고
    • The gastrointestinal tract
    • Kumar V, editor, Philadelphia, PA: Elsevier Saunders
    • Liu C, Crawford JM (2005) The gastrointestinal tract. In: Kumar V, editor. Pathologic Basis of disease. Philadelphia, PA: Elsevier Saunders. 804-805.
    • (2005) Pathologic Basis of Disease , pp. 804-805
    • Liu, C.1    Crawford, J.M.2
  • 36
    • 33748782531 scopus 로고    scopus 로고
    • Histopathologic Evaluation of an Animal Model for Barrett's Esophagus and Adenocarcinoma of the Distal Esophagus
    • DOI 10.1016/j.jss.2006.04.023, PII S0022480406002022
    • Buskens CJ, Hulscher JBF, Van Gulik TM, Ten Kate FJ, Van Lanschot JJB (2006) Histopathologic evaluation of an animal model for Barett's esophagus and adenocarcinoma of the distal esophagus. J Surg Res 135:337-344. (Pubitemid 44414894)
    • (2006) Journal of Surgical Research , vol.135 , Issue.2 , pp. 337-344
    • Buskens, C.J.1    Hulscher, J.B.F.2    Van Gulik, T.M.3    Ten Kate, F.J.4    Van Lanschot, J.J.B.5
  • 37
    • 77749273477 scopus 로고    scopus 로고
    • HER2 expression in gastric cancer. Rare, heterogeneous and of no prognostic valueconclusions from 924 cases of two independent series
    • Grabsch H, Sivakumar S, Gray S, Gabbert HE, Müller W (2010) HER2 expression in gastric cancer. Rare, heterogeneous and of no prognostic valueconclusions from 924 cases of two independent series. Cell Oncol 32:57-65.
    • (2010) Cell Oncol , vol.32 , pp. 57-65
    • Grabsch, H.1    Sivakumar, S.2    Gray, S.3    Gabbert, H.E.4    Müller, W.5
  • 38
    • 61449154484 scopus 로고    scopus 로고
    • KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: Practical application of patient selection
    • Jimeno A, Messersmith WA, Hirsch FR, Franklin WA, Eckhardt SG (2009) KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection. J Clin Oncol 27:1130-1136.
    • (2009) J Clin Oncol , vol.27 , pp. 1130-1136
    • Jimeno, A.1    Messersmith, W.A.2    Hirsch, F.R.3    Franklin, W.A.4    Eckhardt, S.G.5
  • 40
    • 79953786463 scopus 로고    scopus 로고
    • Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China
    • Chen HC, Chen HJ, Khan MA, Rao ZZ, Wan XX, et al. (2011) Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China. Tumor Biol 32:367-373.
    • (2011) Tumor Biol , vol.32 , pp. 367-373
    • Chen, H.C.1    Chen, H.J.2    Khan, M.A.3    Rao, Z.Z.4    Wan, X.X.5
  • 42
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • DOI 10.1038/nrc1097
    • Malumbres M, Barbacid M (2003) RAS oncogenes: the first 30 years. Nat Rev Cancer 3:459-465. (Pubitemid 37328850)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 43
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC, Goddard AD, Heldens SL, et al. (2005) Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 23:5900-5909.
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3    Goddard, A.D.4    Heldens, S.L.5


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