APOE genotype modulates proton magnetic resonance spectroscopy metabolites in the aging brain

Biological Psychiatry

Volumn 75, Issue 9, 2014, Pages 686-692

  Gomar, Jesus J ^a,b   Gordon, Marc L ^a,c   Dickinson, Dwight ^d   Kingsley, Peter B ^e   Uluǧ, Aziz M ^a,c   Keehlisen, Lynda ^a   Huet, Sarah ^a   Buthorn, Justin J ^a   Koppel, Jeremy ^a,c   Christen, Erica ^a   Conejero Goldberg, Concepcion ^a   Davies, Peter ^a,c   Goldberg, Terry E ^a,c  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b FIDMAG Hermanas Hospitalarias ^*  (Spain)

^c DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^e NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

Aging; APOE genotype; cognitive function; KeyWords; neurodegeneration; proton magnetic resonance spectroscopy; structural equation modeling

Indexed keywords

APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; CHOLINE; CREATINE; INOSITOL; APOLIPOPROTEIN E; PROTON;

ADULT; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; BRAIN; COGNITION; COHORT ANALYSIS; EXECUTIVE FUNCTION; FEMALE; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HOMOZYGOTE; HUMAN; MALE; MEMORY; METABOLITE; NORMAL HUMAN; POSTERIOR CINGULATE; PRECUNEUS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SEMANTICS; STRUCTURAL EQUATION MODELING; GENETICS; MENTAL FUNCTION; METABOLISM; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY; PROCEDURES; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AGING; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BRAIN; CHOLINE; CREATINE; FEMALE; GENOTYPE; HUMANS; INOSITOL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MENTAL PROCESSES; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PROTONS;

EID: 84898625633     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.05.022     Document Type: Article

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