ATRX dysfunction induces replication defects in primary mouse cells

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Clynes, David ^a   Jelinska, Clare ^a   Xella, Barbara ^a   Ayyub, Helena ^a   Taylor, Stephen ^a   Mitson, Matthew ^a   Bachrati, Csanád Z ^b   Higgs, Douglas R ^a   Gibbons, Richard J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF LINCOLN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HYDROXYUREA; MRE11 PROTEIN; NIBRIN; PROTEIN ATRX; RAD50 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL SURVIVAL; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA METABOLISM; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; EMBRYO; EMBRYONIC STEM CELL; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; LOSS OF FUNCTION MUTATION; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN DEFECT; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REPLICATION FORK STALLING; SURVIVAL RATE; TELOMERE;

ANIMALS; CELL LINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA HELICASES; DNA REPLICATION; EMBRYONIC STEM CELLS; GENE KNOCKOUT TECHNIQUES; HUMANS; MICE; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; S PHASE; TELOMERE;

EID: 84898619104     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092915     Document Type: Article

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