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Volumn 233, Issue 1, 2014, Pages 74-88

Glioblastoma-associated stromal cells (GASCs) from histologically normal surgical margins have a myofibroblast phenotype and angiogenic properties

Author keywords

cancer associated fibroblasts; glioblastoma; peritumoural brain zone; proteomic; target; translational study

Indexed keywords

CYTOKINE; SCATTER FACTOR; STROMAL CELL DERIVED FACTOR 1;

EID: 84898600179     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4332     Document Type: Article
Times cited : (65)

References (52)
  • 2
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, et al., Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009; 10: 459-466.
    • (2009) Lancet Oncol , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 3
    • 84870508654 scopus 로고    scopus 로고
    • The influence of surgery on recurrence pattern of glioblastoma
    • De Bonis P, Anile C, Pompucci A, et al., The influence of surgery on recurrence pattern of glioblastoma. Clin Neurol Neurosurg 2013; 115: 37-43.
    • (2013) Clin Neurol Neurosurg , vol.115 , pp. 37-43
    • De Bonis, P.1    Anile, C.2    Pompucci, A.3
  • 4
    • 84871799914 scopus 로고    scopus 로고
    • Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma
    • Petrecca K, Guiot M-C, Panet-Raymond V, et al., Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma. J Neurooncol 2013; 111: 19-23.
    • (2013) J Neurooncol , vol.111 , pp. 19-23
    • Petrecca, K.1    Guiot, M.-C.2    Panet-Raymond, V.3
  • 5
    • 84857047902 scopus 로고    scopus 로고
    • Isolation of a new cell population in the glioblastoma microenvironment
    • Clavreul A, Etcheverry A, Chassevent A, et al., Isolation of a new cell population in the glioblastoma microenvironment. J Neurooncol 2011; 106: 493-504.
    • (2011) J Neurooncol , vol.106 , pp. 493-504
    • Clavreul, A.1    Etcheverry, A.2    Chassevent, A.3
  • 6
    • 84881030156 scopus 로고    scopus 로고
    • 'Cancer associated fibroblasts' - More than meets the eye
    • Madar S, Goldstein I, Rotter V,. 'Cancer associated fibroblasts'-more than meets the eye. Trends Mol Med 2013; 19: 447-453.
    • (2013) Trends Mol Med , vol.19 , pp. 447-453
    • Madar, S.1    Goldstein, I.2    Rotter, V.3
  • 7
    • 84876721085 scopus 로고    scopus 로고
    • Carcinoma-associated fibroblasts: Non-neoplastic tumour-promoting mesenchymal cells
    • Polanska UM, Orimo A,. Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells. J Cell Physiol 2013; 228: 1651-1657.
    • (2013) J Cell Physiol , vol.228 , pp. 1651-1657
    • Polanska, U.M.1    Orimo, A.2
  • 8
    • 84871080983 scopus 로고    scopus 로고
    • From sentinel cells to inflammatory culprits: Cancer-associated fibroblasts in tumour-related inflammation
    • Servais C, Erez N,. From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation. J Pathol 2013; 229: 198-207.
    • (2013) J Pathol , vol.229 , pp. 198-207
    • Servais, C.1    Erez, N.2
  • 9
    • 84887557103 scopus 로고    scopus 로고
    • Breast stromal fibroblasts from histologically normal surgical margins are pro-carcinogenic
    • Al-Rakan MA, Colak D, Hendrayani S-F, et al., Breast stromal fibroblasts from histologically normal surgical margins are pro-carcinogenic. J Pathol 2013; 231: 457-465.
    • (2013) J Pathol , vol.231 , pp. 457-465
    • Al-Rakan, M.A.1    Colak, D.2    Hendrayani, S.-F.3
  • 11
    • 0020530724 scopus 로고
    • A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
    • Vindelov LL, Christensen IJ, Nissen NI,. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 1983; 3: 323-327. (Pubitemid 13087609)
    • (1983) Cytometry , vol.3 , Issue.5 , pp. 323-327
    • Vindelov, L.L.1    Christensen, I.J.2    Nissen, N.I.3
  • 12
    • 55049110246 scopus 로고    scopus 로고
    • Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation
    • Ernoult E, Gamelin E, Guette C,. Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation. Proteome Sci 2008; 6: 27.
    • (2008) Proteome Sci , vol.6 , pp. 27
    • Ernoult, E.1    Gamelin, E.2    Guette, C.3
  • 13
    • 23044478689 scopus 로고    scopus 로고
    • High-throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of common variable immune deficiency (CVID)
    • Zeeberg BR, Qin H, Narasimhan S, et al., High-throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of common variable immune deficiency (CVID). BMC Bioinform 2005; 6: 168.
    • (2005) BMC Bioinform , vol.6 , pp. 168
    • Zeeberg, B.R.1    Qin, H.2    Narasimhan, S.3
  • 14
    • 77956182174 scopus 로고    scopus 로고
    • Mesenchymal stem cells as cellular vehicles for delivery of nanoparticles to brain tumors
    • Roger M, Clavreul A, Venier-Julienne MC, et al., Mesenchymal stem cells as cellular vehicles for delivery of nanoparticles to brain tumors. Biomaterials 2010; 31: 8393-8401.
    • (2010) Biomaterials , vol.31 , pp. 8393-8401
    • Roger, M.1    Clavreul, A.2    Venier-Julienne, M.C.3
  • 15
    • 84873720325 scopus 로고    scopus 로고
    • In vitro studies of actin filament and network dynamics
    • Mullins RD, Hansen SD,. In vitro studies of actin filament and network dynamics. Curr Opin Cell Biol 2013; 25: 6-13.
    • (2013) Curr Opin Cell Biol , vol.25 , pp. 6-13
    • Mullins, R.D.1    Hansen, S.D.2
  • 16
    • 70849098888 scopus 로고    scopus 로고
    • Actin, a central player in cell shape and movement
    • Pollard TD, Cooper JA,. Actin, a central player in cell shape and movement. Science 2009; 326: 1208-1212.
    • (2009) Science , vol.326 , pp. 1208-1212
    • Pollard, T.D.1    Cooper, J.A.2
  • 18
    • 0031574279 scopus 로고    scopus 로고
    • Annexins II and V inhibit cell migration
    • DOI 10.1006/excr.1997.3817
    • Balch C, Dedman JR,. Annexins II and V inhibit cell migration. Exp Cell Res 1997; 237: 259-263. (Pubitemid 28027920)
    • (1997) Experimental Cell Research , vol.237 , Issue.2 , pp. 259-263
    • Balch, C.1    Dedman, J.R.2
  • 19
    • 41349121374 scopus 로고    scopus 로고
    • αb-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis
    • Dimberg A, Rylova S, Dieterich LC, et al., αB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis. Blood 2008; 111: 2015-2203.
    • (2008) Blood , vol.111 , pp. 2015-2203
    • Dimberg, A.1    Rylova, S.2    Dieterich, L.C.3
  • 20
    • 84055216939 scopus 로고    scopus 로고
    • B-Crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells
    • Ruan Q, Han S, Jiang WG, Boulton ME, et al., B-Crystallin, an effector of unfolded protein response, confers anti-VEGF resistance to breast cancer via maintenance of intracrine VEGF in endothelial cells. Mol Cancer Res 2011; 9: 1632-1643.
    • (2011) Mol Cancer Res , vol.9 , pp. 1632-1643
    • Ruan, Q.1    Han, S.2    Jiang, W.G.3    Boulton, M.E.4
  • 21
    • 34147161571 scopus 로고    scopus 로고
    • Loss of smooth muscle calponin results in impaired blood vessel maturation in the tumor-host microenvironment
    • DOI 10.1111/j.1349-7006.2007.00452.x
    • Yamamura H, Hirano N, Koyama H, et al., Loss of smooth muscle calponin results in impaired blood vessel maturation in the tumor-host microenvironment. Cancer Sci 2007; 98: 757-763. (Pubitemid 46563455)
    • (2007) Cancer Science , vol.98 , Issue.5 , pp. 757-763
    • Yamamura, H.1    Hirano, N.2    Koyama, H.3    Nishizawa, Y.4    Takahashi, K.5
  • 22
    • 58449122746 scopus 로고    scopus 로고
    • A crucial role of caldesmon in vascular development in vivo
    • Zheng P-P, Severijnen L-A, Van Der Weiden M, et al., A crucial role of caldesmon in vascular development in vivo. Cardiovasc Res 2009; 81: 362-369.
    • (2009) Cardiovasc Res , vol.81 , pp. 362-369
    • Zheng, P.-P.1    Severijnen, L.-A.2    Van Der Weiden, M.3
  • 23
    • 0035117624 scopus 로고    scopus 로고
    • Expression of thrombospondin-1 in pancreatic carcinoma: Correlation with microvessel density
    • DOI 10.1007/s004280000302
    • Kasper HU, Ebert M, Malfertheiner P, et al., Expression of thrombospondin-1 in pancreatic carcinoma: correlation with microvessel density. Virchows Archiv 2001; 438: 116-120. (Pubitemid 32186578)
    • (2001) Virchows Archiv , vol.438 , Issue.2 , pp. 116-120
    • Kasper, H.1    Ebert, M.2    Malfertheiner, P.3    Roessner, A.4    Kirkpatrick, C.5    Wolf, H.6
  • 24
    • 84862786502 scopus 로고    scopus 로고
    • Overexpression of thrombospondin-1 in stromal myofibroblasts is associated with tumor growth and nodal metastasis in gastric carcinoma
    • Lin X-D, Chen S-Q, Qi Y-L, et al., Overexpression of thrombospondin-1 in stromal myofibroblasts is associated with tumor growth and nodal metastasis in gastric carcinoma. J Surg Oncol 2012; 106: 94-100.
    • (2012) J Surg Oncol , vol.106 , pp. 94-100
    • Lin, X.-D.1    Chen, S.-Q.2    Qi, Y.-L.3
  • 25
    • 74549175673 scopus 로고    scopus 로고
    • High-mobility group box 1 and cancer
    • Tang D, Kang R, Zeh HJ, et al., High-mobility group box 1 and cancer. Biochim Biophys Acta 2010; 1799: 131-140.
    • (2010) Biochim Biophys Acta , vol.1799 , pp. 131-140
    • Tang, D.1    Kang, R.2    Zeh, H.J.3
  • 26
    • 84872615463 scopus 로고    scopus 로고
    • Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1
    • Van Beijnum JR, Nowak-Sliwinska P, Van Den Boezem E, et al., Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1. Oncogene 2013; 32: 363-374.
    • (2013) Oncogene , vol.32 , pp. 363-374
    • Van Beijnum, J.R.1    Nowak-Sliwinska, P.2    Van Den Boezem, E.3
  • 27
    • 84872712322 scopus 로고    scopus 로고
    • Overexpression of high mobility group box 1 and 2 is associated with the progression and angiogenesis of human bladder carcinoma
    • Wang W, Jiang H, Zhu H, et al., Overexpression of high mobility group box 1 and 2 is associated with the progression and angiogenesis of human bladder carcinoma. Oncol Lett 2013; 5: 884-888.
    • (2013) Oncol Lett , vol.5 , pp. 884-888
    • Wang, W.1    Jiang, H.2    Zhu, H.3
  • 28
    • 84862005373 scopus 로고    scopus 로고
    • ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1
    • Avraham-Davidi I, Ely Y, Pham VN, et al., ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nat Med 2012; 18: 967-973.
    • (2012) Nat Med , vol.18 , pp. 967-973
    • Avraham-Davidi, I.1    Ely, Y.2    Pham, V.N.3
  • 29
    • 79960930688 scopus 로고    scopus 로고
    • Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma
    • Wang J, Svendsen A, Kmiecik J, et al., Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma. PLoS One 2011; 6: 14.
    • (2011) PLoS One , vol.6 , pp. 14
    • Wang, J.1    Svendsen, A.2    Kmiecik, J.3
  • 30
    • 84871567949 scopus 로고    scopus 로고
    • Anti-S100A4 antibody suppresses metastasis formation by blocking stroma cell invasion
    • Klingelhöfer J, Grum-Schwensen B, Beck MK, et al., Anti-S100A4 antibody suppresses metastasis formation by blocking stroma cell invasion. Neoplasia 2012; 14: 1260-1268.
    • (2012) Neoplasia , vol.14 , pp. 1260-1268
    • Klingelhöfer, J.1    Grum-Schwensen, B.2    Beck, M.K.3
  • 31
    • 77951448229 scopus 로고    scopus 로고
    • αb-crystallin regulation of angiogenesis by modulation of VEGF
    • Kase S, He S, Sonoda S, et al., αB-crystallin regulation of angiogenesis by modulation of VEGF. Blood 2010; 115: 3398-3406.
    • (2010) Blood , vol.115 , pp. 3398-3406
    • Kase, S.1    He, S.2    Sonoda, S.3
  • 32
    • 77957356733 scopus 로고    scopus 로고
    • Focal adhesion assembly in myofibroblasts fosters a microenvironment that promotes tumor growth
    • Kang N, Yaqoob U, Geng Z, et al., Focal adhesion assembly in myofibroblasts fosters a microenvironment that promotes tumor growth. Am J Pathol 2010; 177: 1888-1900.
    • (2010) Am J Pathol , vol.177 , pp. 1888-1900
    • Kang, N.1    Yaqoob, U.2    Geng, Z.3
  • 33
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • Orimo A, Gupta PB, Sgroi DC, et al., Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005; 121: 335-348. (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 34
    • 35148873112 scopus 로고    scopus 로고
    • In vivo imaging of the systemic recruitment of fibroblasts to the angiogenic rim of ovarian carcinoma tumors
    • DOI 10.1158/0008-5472.CAN-07-0684
    • Granot D, Addadi Y, Kalchenko V, et al., In vivo imaging of the systemic recruitment of fibroblasts to the angiogenic rim of ovarian carcinoma tumors. Cancer Res 2007; 67: 9180-9189. (Pubitemid 47535904)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 9180-9189
    • Granot, D.1    Addadi, Y.2    Kalchenko, V.3    Harmelin, A.4    Kunz-Schughart, L.A.5    Neeman, M.6
  • 35
    • 28544451204 scopus 로고    scopus 로고
    • Orthotopic growth of human glioma cells quantitatively and qualitatively influences radiation-induced changes in gene expression
    • DOI 10.1158/0008-5472.CAN-05-1904
    • Camphausen K, Purow B, Sproull M, et al., Orthotopic growth of human glioma cells quantitatively and qualitatively influences radiation-induced changes in gene expression. Cancer Res 2005; 65: 10389-10393. (Pubitemid 41743732)
    • (2005) Cancer Research , vol.65 , Issue.22 , pp. 10389-10393
    • Camphausen, K.1    Purow, B.2    Sproull, M.3    Scott, T.4    Ozawa, T.5    Deen, D.F.6    Tofilon, P.J.7
  • 36
    • 84860130221 scopus 로고    scopus 로고
    • Anti-VEGF/VEGFR therapy for cancer: Reassessing the target
    • Sitohy B, Nagy JA, Dvorak HF,. Anti-VEGF/VEGFR therapy for cancer: reassessing the target. Cancer Res 2012; 72: 1909-1914.
    • (2012) Cancer Res , vol.72 , pp. 1909-1914
    • Sitohy, B.1    Nagy, J.A.2    Dvorak, H.F.3
  • 37
    • 84878991085 scopus 로고    scopus 로고
    • Bevacizumab for the treatment of glioblastoma
    • Gil-Gil MJ, Mesia C, Rey M, et al., Bevacizumab for the treatment of glioblastoma. Clin Med Insights Oncol 2013; 7: 123-135.
    • (2013) Clin Med Insights Oncol , vol.7 , pp. 123-135
    • Gil-Gil, M.J.1    Mesia, C.2    Rey, M.3
  • 38
    • 62649101158 scopus 로고    scopus 로고
    • Cancer: The nuances of therapy
    • Ellis LM, Reardon DA,. Cancer: the nuances of therapy. Nature 2009; 458: 290-292.
    • (2009) Nature , vol.458 , pp. 290-292
    • Ellis, L.M.1    Reardon, D.A.2
  • 39
    • 84862766496 scopus 로고    scopus 로고
    • Glioblastoma angiogenesis: VEGF resistance solutions and new strategies based on molecular mechanisms of tumor vessel formation
    • Takano S., Glioblastoma angiogenesis: VEGF resistance solutions and new strategies based on molecular mechanisms of tumor vessel formation. Brain Tumor Pathol 2012; 29: 73-86.
    • (2012) Brain Tumor Pathol , vol.29 , pp. 73-86
    • Takano, S.1
  • 40
    • 84877098516 scopus 로고    scopus 로고
    • Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance
    • Jahangiri A, De Lay M, Miller LM, et al., Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance. Clin Cancer Res 2013; 19: 1773-1783.
    • (2013) Clin Cancer Res , vol.19 , pp. 1773-1783
    • Jahangiri, A.1    De Lay, M.2    Miller, L.M.3
  • 41
    • 84896739683 scopus 로고    scopus 로고
    • Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma
    • Lu KV, Bergers G,. Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma. CNS Oncol 2013; 2: 49-65.
    • (2013) CNS Oncol , vol.2 , pp. 49-65
    • Lu, K.V.1    Bergers, G.2
  • 42
    • 84877087466 scopus 로고    scopus 로고
    • Glioblastoma resistance to anti-VEGF therapy: Has the challenge been MET?
    • McCarty JH,. Glioblastoma resistance to anti-VEGF therapy: has the challenge been MET? Clin Cancer Res 2013; 19: 1631-1633.
    • (2013) Clin Cancer Res , vol.19 , pp. 1631-1633
    • McCarty, J.H.1
  • 43
    • 84863754907 scopus 로고    scopus 로고
    • VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
    • Lu KV, Chang JP, Parachoniak CA, et al., VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell 2012; 22: 21-35.
    • (2012) Cancer Cell , vol.22 , pp. 21-35
    • Lu, K.V.1    Chang, J.P.2    Parachoniak, C.A.3
  • 44
    • 79952740612 scopus 로고    scopus 로고
    • Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
    • Keunen O, Johansson M, Oudin A, et al., Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc Natl Acad Sci USA 2011; 108: 3749-3754.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3749-3754
    • Keunen, O.1    Johansson, M.2    Oudin, A.3
  • 45
    • 84874593624 scopus 로고    scopus 로고
    • Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2
    • Navis AC, Bourgonje A, Wesseling P, et al., Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2. PLoS One 2013; 8: e58262.
    • (2013) PLoS One , vol.8
    • Navis, A.C.1    Bourgonje, A.2    Wesseling, P.3
  • 46
    • 78651408563 scopus 로고    scopus 로고
    • Glioblastoma recurrence after cediranib therapy in patients: Lack of 'rebound' revascularization as mode of escape
    • Di Tomaso E, Snuderl M, Kamoun WS, et al., Glioblastoma recurrence after cediranib therapy in patients: lack of 'rebound' revascularization as mode of escape. Cancer Res 2011; 71: 19-28.
    • (2011) Cancer Res , vol.71 , pp. 19-28
    • Di Tomaso, E.1    Snuderl, M.2    Kamoun, W.S.3
  • 47
    • 84860801440 scopus 로고    scopus 로고
    • Galectin-1, a gene preferentially expressed at the tumor margin, promotes glioblastoma cell invasion
    • Toussaint LG, Nilson AE, Goble JM, et al., Galectin-1, a gene preferentially expressed at the tumor margin, promotes glioblastoma cell invasion. Mol Cancer 2012; 11: 32.
    • (2012) Mol Cancer , vol.11 , pp. 32
    • Toussaint, L.G.1    Nilson, A.E.2    Goble, J.M.3
  • 48
    • 77956920108 scopus 로고    scopus 로고
    • Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis
    • Brunckhorst MK, Wang H, Lu R, et al., Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis. Cancer Res 2010; 70: 7283-7293.
    • (2010) Cancer Res , vol.70 , pp. 7283-7293
    • Brunckhorst, M.K.1    Wang, H.2    Lu, R.3
  • 49
    • 76249133170 scopus 로고    scopus 로고
    • Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma
    • Huang D, Ding Y, Zhou M, et al., Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Res 2010; 70: 1063-1071.
    • (2010) Cancer Res , vol.70 , pp. 1063-1071
    • Huang, D.1    Ding, Y.2    Zhou, M.3
  • 50
    • 84887419886 scopus 로고    scopus 로고
    • Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation
    • Batchelor TT, Gerstner ER, Emblem KE, et al., Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation. Proc Natl Acad Sci USA 2013; 110: 19059-19064.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 19059-19064
    • Batchelor, T.T.1    Gerstner, E.R.2    Emblem, K.E.3
  • 51
    • 79952538238 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib
    • Welti JC, Gourlaouen M, Powles T, et al., Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib. Oncogene 2011; 30: 1183-1193.
    • (2011) Oncogene , vol.30 , pp. 1183-1193
    • Welti, J.C.1    Gourlaouen, M.2    Powles, T.3
  • 52
    • 57349160348 scopus 로고    scopus 로고
    • Exploring multi-targeting strategies for the treatment of gliomas
    • Omuro AM,. Exploring multi-targeting strategies for the treatment of gliomas. Curr Opin Invest Drugs 2008; 9: 1287-1295.
    • (2008) Curr Opin Invest Drugs , vol.9 , pp. 1287-1295
    • Omuro, A.M.1


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