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EMBO Molecular Medicine
Volumn 6, Issue 4, 2014, Pages 434-435
A magic bullet to specifically eliminate mutated mitochondrial genomes from patients' cells
Author keywords

[No Author keywords available]
Indexed keywords

MITOCHONDRIAL DNA; RESTRICTION ENDONUCLEASE; VIRUS VECTOR;
EID: 84898596309     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201303769     Document Type: Article
Times cited : (21)
References (9)
  • 1
    • 84869089115 scopus 로고    scopus 로고
    • Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease
    • Bacman SR, Williams SL, Duan D, Moraes CT (2012) Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease. Gene Ther 19: 1101-1106
    • (2012) Gene Ther , vol.19 , pp. 1101-1106
    • Bacman, S.R.1    Williams, S.L.2    Duan, D.3    Moraes, C.T.4
  • 2
    • 77953480318 scopus 로고    scopus 로고
    • Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease
    • Bacman SR, Williams SL, Garcia S, Moraes CT (2010) Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease. Gene Ther 17: 713-720
    • (2010) Gene Ther , vol.17 , pp. 713-720
    • Bacman, S.R.1    Williams, S.L.2    Garcia, S.3    Moraes, C.T.4
  • 3
    • 84883778302 scopus 로고    scopus 로고
    • Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs
    • Bacman SR, Williams SL, Pinto M, Peralta S, Moraes CT (2013) Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs. Nat Med 19: 1111-1113
    • (2013) Nat Med , vol.19 , pp. 1111-1113
    • Bacman, S.R.1    Williams, S.L.2    Pinto, M.3    Peralta, S.4    Moraes, C.T.5
  • 4
    • 79961211249 scopus 로고    scopus 로고
    • The implications of mitochondrial DNA copy number regulation during embryogenesis
    • Carling PJ, Cree LM, Chinnery PF (2011) The implications of mitochondrial DNA copy number regulation during embryogenesis. Mitochondrion 11: 686-692
    • (2011) Mitochondrion , vol.11 , pp. 686-692
    • Carling, P.J.1    Cree, L.M.2    Chinnery, P.F.3
  • 5
    • 84898602295 scopus 로고    scopus 로고
    • Mitochondrially-targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations
    • Gammage PA, Rorbacha J, Vincentb AI, Rebarb EJ, Minczuk M (2014) Mitochondrially-targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations. EMBO Mol Med 6: 458-466
    • (2014) EMBO Mol Med , vol.6 , pp. 458-466
    • Gammage, P.A.1    Rorbacha, J.2    Vincentb, A.I.3    Rebarb, E.J.4    Minczuk, M.5
  • 6
    • 79954622209 scopus 로고    scopus 로고
    • Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
    • Mingozzi F, High KA (2011) Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges. Nat Rev Genet 12: 341-355
    • (2011) Nat Rev Genet , vol.12 , pp. 341-355
    • Mingozzi, F.1    High, K.A.2
  • 7
    • 84873566329 scopus 로고    scopus 로고
    • Zinc finger nucleases: looking toward translation
    • Palpant NJ, Dudzinski D (2013) Zinc finger nucleases: looking toward translation. Gene Ther 20: 121-127
    • (2013) Gene Ther , vol.20 , pp. 121-127
    • Palpant, N.J.1    Dudzinski, D.2
  • 8
    • 84869397441 scopus 로고    scopus 로고
    • Human mitochondrial DNA: roles of inherited and somatic mutations
    • Schon EA, DiMauro S, Hirano M (2012) Human mitochondrial DNA: roles of inherited and somatic mutations. Nat Rev Genet 13: 878-890
    • (2012) Nat Rev Genet , vol.13 , pp. 878-890
    • Schon, E.A.1    DiMauro, S.2    Hirano, M.3
  • 9
    • 0028140454 scopus 로고
    • Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy
    • Sciacco M, Bonilla E, Schon EA, DiMauro S, Moraes CT (1994) Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy. Hum Mol Genet 3: 13-19
    • (1994) Hum Mol Genet , vol.3 , pp. 13-19
    • Sciacco, M.1    Bonilla, E.2    Schon, E.A.3    DiMauro, S.4    Moraes, C.T.5

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.