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Volumn 24, Issue 3, 2014, Pages 303-310

Genomic analysis in active surveillance: Predicting high-risk disease using tissue biomarkers

Author keywords

active surveillance; biomarkers; liquid biopsy; systems pathology

Indexed keywords

ANDROGEN RECEPTOR; BIOLOGICAL MARKER; HISTONE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN P53; TMPRSS2 PROTEIN; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR EZH2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; TUMOR MARKER;

EID: 84898549199     PISSN: 09630643     EISSN: 14736586     Source Type: Journal    
DOI: 10.1097/MOU.0000000000000051     Document Type: Review
Times cited : (6)

References (62)
  • 1
    • 84890798275 scopus 로고    scopus 로고
    • The prostate cancer genome: Perspectives and potential
    • Barbieri CE, Tomlins SA. The prostate cancer genome: perspectives and potential. Urol Oncol 2014; 32:53e15-53e22.
    • (2014) Urol Oncol , vol.32
    • Barbieri, C.E.1    Tomlins, S.A.2
  • 2
    • 67649935641 scopus 로고    scopus 로고
    • Genomic approaches to outcome prediction in prostate cancer
    • Febbo PG. Genomic approaches to outcome prediction in prostate cancer. Cancer 2009; 115:3046-3057.
    • (2009) Cancer , vol.115 , pp. 3046-3057
    • Febbo, P.G.1
  • 3
    • 84873696198 scopus 로고    scopus 로고
    • The genomic landscape of prostate cancer
    • Baca SC, Garraway L. The genomic landscape of prostate cancer. Front Endocrinol 2012; 3:1-9.
    • (2012) Front Endocrinol , vol.3 , pp. 1-9
    • Baca, S.C.1    Garraway, L.2
  • 4
    • 84887429673 scopus 로고    scopus 로고
    • Tracking the clonal origin of lethal prostate cancer
    • Haffner MC, Mosbruger T, Esopi D, Fedor H, et al. Tracking the clonal origin of lethal prostate cancer. J Clin Invest 2013; 123:4918-4922.
    • (2013) J Clin Invest , vol.123 , pp. 4918-4922
    • Haffner, M.C.1    Mosbruger, T.2    Esopi, D.3    Fedor, H.4
  • 5
    • 0024779260 scopus 로고
    • Latent prostatic carcinoma: Pathological and epidemiological aspects
    • Yatani R, Kusano I, Shiraishi T, et al. Latent prostatic carcinoma: pathological and epidemiological aspects. Jpn J Clin Oncol 1989; 19:319-326.
    • (1989) Jpn J Clin Oncol , vol.19 , pp. 319-326
    • Yatani, R.1    Kusano, I.2    Shiraishi, T.3
  • 6
    • 47749087500 scopus 로고    scopus 로고
    • Integrating differentiation and cancer: The Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis
    • Abate-Shen C, SHen MM, Gelmann E. Integrating differentiation and cancer: the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis. Differentiation 2008; 76:717-727.
    • (2008) Differentiation , vol.76 , pp. 717-727
    • Abate-Shen, C.1    Shen, M.M.2    Gelmann, E.3
  • 7
    • 84876418408 scopus 로고    scopus 로고
    • Stabilization of the prostatespecific tumor suppressor NKX3.1 by the oncogenic protein kinase Pim-1 in prostate cancer cells
    • Padmanabhan A, Gosc EB, Bieberich CJ. Stabilization of the prostatespecific tumor suppressor NKX3.1 by the oncogenic protein kinase Pim-1 in prostate cancer cells. Hum Mol Genet 2013; 22:408-415.
    • (2013) Hum Mol Genet , vol.22 , pp. 408-415
    • Padmanabhan, A.1    Gosc, E.B.2    Bieberich, C.J.3
  • 8
    • 33646342738 scopus 로고    scopus 로고
    • NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss
    • Lei Q, Jiao J, Xin L, et al. NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. Cancer Cell 2006; 9:367-378.
    • (2006) Cancer Cell , vol.9 , pp. 367-378
    • Lei, Q.1    Jiao, J.2    Xin, L.3
  • 9
    • 71249101060 scopus 로고    scopus 로고
    • Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
    • Lin C, Yang L, Tanasa B, et al. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell 2009; 139:1069-1083.
    • (2009) Cell , vol.139 , pp. 1069-1083
    • Lin, C.1    Yang, L.2    Tanasa, B.3
  • 10
    • 77951981568 scopus 로고    scopus 로고
    • Theranostic and prognostic biomarkers: Genomic applications in urological malignancies
    • Netto GJ, Epstein JI. Theranostic and prognostic biomarkers: genomic applications in urological malignancies. Pathology 2010; 42:384-394.
    • (2010) Pathology , vol.42 , pp. 384-394
    • Netto, G.J.1    Epstein, J.I.2
  • 11
    • 79951512852 scopus 로고    scopus 로고
    • SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
    • Ding Z, Wu C-J, Chu GC, et al. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature 2011; 470:269-273.
    • (2011) Nature , vol.470 , pp. 269-273
    • Ding, Z.1    Wu, C.-J.2    Chu, G.C.3
  • 12
    • 84872161627 scopus 로고    scopus 로고
    • COUP-TFII inhibits TGF-binduced growth barrier to promote prostate tumorigenesis
    • Qin J, San-Pin Wu. Creighton C, Dai F, et al. COUP-TFII inhibits TGF-binduced growth barrier to promote prostate tumorigenesis. Nature 2013; 493:236-240.
    • (2013) Nature , vol.493 , pp. 236-240
    • Qin, J.1    Wu, S.2    Creighton, C.3    Dai, F.4
  • 13
    • 80052260149 scopus 로고    scopus 로고
    • Epigenetics in prostate cancer: Biologic and clinical relevance
    • Jeronimo C, Bastian P, Bjartell A, Carbone G, et al. Epigenetics in prostate cancer: biologic and clinical relevance. Eur Urol 2011; 60:753-766.
    • (2011) Eur Urol , vol.60 , pp. 753-766
    • Jeronimo, C.1    Bastian, P.2    Bjartell, A.3    Carbone, G.4
  • 14
    • 84879436659 scopus 로고    scopus 로고
    • Molecular diagnosis of prostate cancer: Are we up to age?
    • Bhavsar T, McCue P, Birbe R. Molecular diagnosis of prostate cancer: are we up to age? Semin Oncol 2013; 40:259-275.
    • (2013) Semin Oncol , vol.40 , pp. 259-275
    • Bhavsar, T.1    McCue, P.2    Birbe, R.3
  • 15
    • 0037474235 scopus 로고    scopus 로고
    • Epigenetic regulation of a novel tumor suppressor gene (DAB2IP) in prostate cancer cell lines
    • Chen H, Toyooka S, Gazdar AF, et al. Epigenetic regulation of a novel tumor suppressor gene (DAB2IP) in prostate cancer cell lines. J Biol Chem 2003; 278:3121-3130.
    • (2003) J Biol Chem , vol.278 , pp. 3121-3130
    • Chen, H.1    Toyooka, S.2    Gazdar, A.F.3
  • 16
    • 77749297990 scopus 로고    scopus 로고
    • An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB
    • Min J, Zaslavsky A, Fedele G, et al. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB. Nat Med 2010; 16:286-294.
    • (2010) Nat Med , vol.16 , pp. 286-294
    • Min, J.1    Zaslavsky, A.2    Fedele, G.3
  • 17
    • 84883476051 scopus 로고    scopus 로고
    • The mechanism of DAB2IP in chemoresistance of prostate cancer cells
    • Wu K, Xie D, Zou Y, Zhang T, et al. The mechanism of DAB2IP in chemoresistance of prostate cancer cells. Clin Cancer Res 2013; 19:4740- 4749.
    • (2013) Clin Cancer Res , vol.19 , pp. 4740-4749
    • Wu, K.1    Xie, D.2    Zou, Y.3    Zhang, T.4
  • 18
    • 51649109226 scopus 로고    scopus 로고
    • Comparison of nomograms and other methods for predicting outcomes in prostate cancer: A critical analysis of the literature
    • Shariat SF, Karakiewicz PI, Suardi N, et al. Comparison of nomograms and other methods for predicting outcomes in prostate cancer: a critical analysis of the literature. Clin Cancer Res 2008; 14:4400-4407.
    • (2008) Clin Cancer Res , vol.14 , pp. 4400-4407
    • Shariat, S.F.1    Karakiewicz, P.I.2    Suardi, N.3
  • 19
    • 60049096847 scopus 로고    scopus 로고
    • Prostate cancer: The new landscape
    • Moul JW, Mouraviev V, Sun L, et al. Prostate cancer: the new landscape. Curr Opin Urol 2009; 19:154-160.
    • (2009) Curr Opin Urol , vol.19 , pp. 154-160
    • Moul, J.W.1    Mouraviev, V.2    Sun, L.3
  • 20
    • 67649713132 scopus 로고    scopus 로고
    • Management of localized prostate cancer in men over 65 years
    • Cooperberg MR, Konety BR. Management of localized prostate cancer in men over 65 years. Curr Opin Urol 2009; 19:309-314.
    • (2009) Curr Opin Urol , vol.19 , pp. 309-314
    • Cooperberg, M.R.1    Konety, B.R.2
  • 21
    • 63249122661 scopus 로고    scopus 로고
    • Mortality results from a randomized prostate-cancer screening trial
    • Andriole GL, Crawford ED, Grubb RL, et al. Mortality results from a randomized prostate-cancer screening trial. N Engl J Med 2009; 360:1310- 1319.
    • (2009) N Engl J Med , vol.360 , pp. 1310-1319
    • Andriole, G.L.1    Crawford, E.D.2    Grubb, R.L.3
  • 22
    • 63249118690 scopus 로고    scopus 로고
    • Screening and prostate-cancer mortality in a randomized European study
    • Schroder FH, Hugosson J, Roobol MJ, et al. Screening and prostate-cancer mortality in a randomized European study. N Engl J Med 2009; 360:1320- 1328.
    • (2009) N Engl J Med , vol.360 , pp. 1320-1328
    • Schroder, F.H.1    Hugosson, J.2    Roobol, M.J.3
  • 23
    • 84876410479 scopus 로고    scopus 로고
    • A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and nonaggressive disease
    • Amin A-O, Kote-Jarai Z, Schumacher FR, Wiklund F. A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and nonaggressive disease. Expert Opin Ther Targets 2012; 16:121-130.
    • (2012) Expert Opin Ther Targets , vol.16 , pp. 121-130
    • Amin, A.-O.1    Kote-Jarai, Z.2    Schumacher, F.R.3    Wiklund, F.4
  • 24
    • 84899529644 scopus 로고    scopus 로고
    • Prostate cancer (PCa) risk variants and risk of fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    • [Epub 7ahead of print].in press
    • Shui I, Lindstrom S, Kibel A, Berndt S, et al. Prostate cancer (PCa) risk variants and risk of fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Eur Urol 2014. [Epub 7ahead of print].in press, http://dx.doi.org/10.1016/j.eururo.2013.12.058.
    • (2014) Eur Urol
    • Shui, I.1    Lindstrom, S.2    Kibel, A.3    Berndt, S.4
  • 25
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005; 310:644- 648.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 26
    • 34447342868 scopus 로고    scopus 로고
    • TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion
    • Perner S, Mosquera J-M, Demichelis F, et al. TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. Am J Surg Pathol 2007; 31:882-888.
    • (2007) Am J Surg Pathol , vol.31 , pp. 882-888
    • Perner, S.1    Mosquera, J.-M.2    Demichelis, F.3
  • 27
    • 34247363715 scopus 로고    scopus 로고
    • Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer
    • Mehra R, Tomlins SA, Shen R, et al. Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer. Mod Pathol 2007; 20:538-544.
    • (2007) Mod Pathol , vol.20 , pp. 538-544
    • Mehra, R.1    Tomlins, S.A.2    Shen, R.3
  • 28
    • 66749188650 scopus 로고    scopus 로고
    • Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
    • Carver BS, Tran J, Gopalan A, Chen Z, et al. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat Genet 2009; 41:619-624.
    • (2009) Nat Genet , vol.41 , pp. 619-624
    • Carver, B.S.1    Tran, J.2    Gopalan, A.3    Chen, Z.4
  • 30
    • 76949106361 scopus 로고    scopus 로고
    • Molecular characterization of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
    • Reid AH, Attard G, Ambroisine L, Fisher G, et al. Molecular characterization of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. Br J Cancer 2010; 102:678-684.
    • (2010) Br J Cancer , vol.102 , pp. 678-684
    • Reid, A.H.1    Attard, G.2    Ambroisine, L.3    Fisher, G.4
  • 31
    • 68249083702 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression
    • Han B, Mehra R, Lonigro RJ, Wang L, et al. Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression. Mod Pathol 2009; 22:1083-1093.
    • (2009) Mod Pathol , vol.22 , pp. 1083-1093
    • Han, B.1    Mehra, R.2    Lonigro, R.J.3    Wang, L.4
  • 32
    • 38049123346 scopus 로고    scopus 로고
    • Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
    • Attard G, Clark J, Ambroisine L, et al. Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene 2009; 27:253-263.
    • (2009) Oncogene , vol.27 , pp. 253-263
    • Attard, G.1    Clark, J.2    Ambroisine, L.3
  • 33
    • 70350109641 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer
    • Clark JP, Cooper CS. ETS gene fusions in prostate cancer. Nat Rev Urol 2009; 6:429-439.
    • (2009) Nat Rev Urol , vol.6 , pp. 429-439
    • Clark, J.P.1    Cooper, C.S.2
  • 34
    • 60549107254 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    • Gopalan A, Leversha MA, Satagopan JM, Zhou Q, et al. TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res 2009; 69:1400-1406.
    • (2009) Cancer Res , vol.69 , pp. 1400-1406
    • Gopalan, A.1    Leversha, M.A.2    Satagopan, J.M.3    Zhou, Q.4
  • 35
    • 84866172302 scopus 로고    scopus 로고
    • The TMPRSS2:ERG rearrangement, ERG expression and prostate cancer outcomes: A cohort study and metaanalysis
    • Pettersson A, Graff RE, Bauer SR, et al. The TMPRSS2:ERG rearrangement, ERG expression and prostate cancer outcomes: a cohort study and metaanalysis. Cancer Epidemiol Biomarkers Prev 2012; 21:1497-1509.
    • (2012) Cancer Epidemiol Biomarkers Prev , vol.21 , pp. 1497-1509
    • Pettersson, A.1    Graff, R.E.2    Bauer, S.R.3
  • 36
    • 84877097685 scopus 로고    scopus 로고
    • Urinary TMPRSS2:ERGand PCA3 in an active surveillance cohort: Results from a baseline analysis in the Canary Prostate Active Surveillance Study
    • Lin DW, Newcomb LF, Brown EC, et al. Urinary TMPRSS2:ERGand PCA3 in an active surveillance cohort: results from a baseline analysis in the Canary Prostate Active Surveillance Study. Clin Cancer Res 2013; 19:2442- 2450.
    • (2013) Clin Cancer Res , vol.19 , pp. 2442-2450
    • Lin, D.W.1    Newcomb, L.F.2    Brown, E.C.3
  • 37
    • 34548863661 scopus 로고    scopus 로고
    • Detection of TMPRSS2- ERG transcripts and prostate cancer antigen 3 in urinary sediments
    • may improve the diagnosis of prostate cancer
    • Hessles D, Smit FP, Verhaegh GW, Witjes JA, et al. Detection of TMPRSS2- ERG transcripts and prostate cancer antigen 3 in urinary sediments may improve the diagnosis of prostate cancer. Clin Cancer Res 2007; 13:5103- 5108.
    • (2007) Clin Cancer Res , vol.13 , pp. 5103-5108
    • Hessles, D.1    Smit, F.P.2    Verhaegh, G.W.3    Witjes, J.A.4
  • 38
    • 84875333536 scopus 로고    scopus 로고
    • ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients
    • Baena E, Shao Z, Linn DE, Glass K. ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. Genes Dev 2013; 27:683-698.
    • (2013) Genes Dev , vol.27 , pp. 683-698
    • Baena, E.1    Shao, Z.2    Linn, D.E.3    Glass, K.4
  • 39
    • 79955968629 scopus 로고    scopus 로고
    • Mechanistic rationale for inhibition of Poly(ADP-Ribose) polymerase in ETS gene fusion-positive cancer
    • Brenner JC, Ateeq B, Li Y, Yocum A, et al. Mechanistic rationale for inhibition of Poly(ADP-Ribose) polymerase in ETS gene fusion-positive cancer. Cancer Cell 2012; 19:664-678.
    • (2012) Cancer Cell , vol.19 , pp. 664-678
    • Brenner, J.C.1    Ateeq, B.2    Li, Y.3    Yocum, A.4
  • 41
    • 77956584765 scopus 로고    scopus 로고
    • Array CGH as a potential predictor of radiocurability in intermediate risk prostate cancer
    • Ishkanian AS, Zafarana G, Thomas J, et al. Array CGH as a potential predictor of radiocurability in intermediate risk prostate cancer. Acta Oncol 2010; 49:888-894.
    • (2010) Acta Oncol , vol.49 , pp. 888-894
    • Ishkanian, A.S.1    Zafarana, G.2    Thomas, J.3
  • 42
    • 79951497419 scopus 로고    scopus 로고
    • The genomic complexity of primary human prostate cancer
    • Berger MF, Lawrence MS, Demichelis F, et al. The genomic complexity of primary human prostate cancer. Nature 2011; 470:214-220.
    • (2011) Nature , vol.470 , pp. 214-220
    • Berger, M.F.1    Lawrence, M.S.2    Demichelis, F.3
  • 44
    • 77954255681 scopus 로고    scopus 로고
    • Integrative genomic proofing of human prostate cancer
    • Taylor BS, Schulta N, Hieronymus H, et al. Integrative genomic proofing of human prostate cancer. Cancer Cell 2010; 18:11-22.
    • (2010) Cancer Cell , vol.18 , pp. 11-22
    • Taylor, B.S.1    Schulta, N.2    Hieronymus, H.3
  • 45
    • 84898541341 scopus 로고    scopus 로고
    • Molecular classification of prostate cancer using curated expression signatures
    • Markert EK, Mizuno H, Vazques A, Levine AJ. Molecular classification of prostate cancer using curated expression signatures. Cancer Cell 2012; 22:373-388.
    • (2012) Cancer Cell , vol.22 , pp. 373-388
    • Markert, E.K.1    Mizuno, H.2    Vazques, A.3    Levine, A.J.4
  • 46
    • 33846049942 scopus 로고    scopus 로고
    • Technology insight: Will systems pathology replace the pathologist?
    • Saidi O, Cordon-Cardo C, Costa J. Technology insight: will systems pathology replace the pathologist? Nat Clin Pract Urol 2007; 4:39-45.
    • (2007) Nat Clin Pract Urol , vol.4 , pp. 39-45
    • Saidi, O.1    Cordon-Cardo, C.2    Costa, J.3
  • 47
    • 43049136191 scopus 로고    scopus 로고
    • Is clinical systems pathology the future of pathology?
    • Costa J. Is clinical systems pathology the future of pathology? Arch Pathol Lab Med 2008; 132:774-776.
    • (2008) Arch Pathol Lab Med , vol.132 , pp. 774-776
    • Costa, J.1
  • 48
    • 34447123124 scopus 로고    scopus 로고
    • Improved prediction of prostate cancer recurrence through systems pathology
    • Cordon-Cardo C, Kotsianti A, Verbel D, et al. Improved prediction of prostate cancer recurrence through systems pathology. J Clin Invest 2007; 117:1876- 1883.
    • (2007) J Clin Invest , vol.117 , pp. 1876-1883
    • Cordon-Cardo, C.1    Kotsianti, A.2    Verbel, D.3
  • 49
    • 67649935640 scopus 로고    scopus 로고
    • Systems pathology: A paradigm shift in the practice of diagnostic and predictive pathology
    • Donovan MJ, Costa J, Cordon-Cardo C. Systems pathology: a paradigm shift in the practice of diagnostic and predictive pathology. Cancer 2009; 115:3078-3084.
    • (2009) Cancer , vol.115 , pp. 3078-3084
    • Donovan, M.J.1    Costa, J.2    Cordon-Cardo, C.3
  • 50
    • 67349084186 scopus 로고    scopus 로고
    • Personalized prediction of tumor response and cancer progression on prostate needle biopsy
    • Donovan MJ, Khan FH, Fernandez G, et al. Personalized prediction of tumor response and cancer progression on prostate needle biopsy. J Urol 2009; 1:125-132.
    • (2009) J Urol , vol.1 , pp. 125-132
    • Donovan, M.J.1    Khan, F.H.2    Fernandez, G.3
  • 51
    • 50549102746 scopus 로고    scopus 로고
    • Systems pathology approach for the prediction of prostate cancer progression after radical prostatectomy
    • Donovan MJ, Hamann S, Clayton M, et al. Systems pathology approach for the prediction of prostate cancer progression after radical prostatectomy. J Clin Oncol 2008; 26:3923-3929.
    • (2008) J Clin Oncol , vol.26 , pp. 3923-3929
    • Donovan, M.J.1    Hamann, S.2    Clayton, M.3
  • 52
    • 84876412076 scopus 로고    scopus 로고
    • Previously developed systems-based model (Prostate PxBE;) identifies favorable-risk prostate cancer for men enrolled in active surveillance program
    • Donovan MJ, Khan FH, Powell D, et al. Previously developed systems-based model (Prostate PxBE;) identifies favorable-risk prostate cancer for men enrolled in active surveillance program. J Urol 2011; 185:e517-e518.
    • (2011) J Urol , vol.185
    • Donovan, M.J.1    Khan, F.H.2    Powell, D.3
  • 53
    • 84866021276 scopus 로고    scopus 로고
    • Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch and hedgehog-dependent tumor-initiating cells
    • Domingo-Domenech J, Vidal SJ, Rodriguez-Bravo V, et al. Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch and hedgehog-dependent tumor-initiating cells. Cancer Cell 2012; 22:373- 388.
    • (2012) Cancer Cell , vol.22 , pp. 373-388
    • Domingo-Domenech, J.1    Vidal, S.J.2    Rodriguez-Bravo, V.3
  • 54
    • 77958086765 scopus 로고    scopus 로고
    • Exosomal membrane molecules are potent immune response modulators
    • Anand PK. Exosomal membrane molecules are potent immune response modulators. Commun Integr Biol 2010; 3:405-408.
    • (2010) Commun Integr Biol , vol.3 , pp. 405-408
    • Anand, P.K.1
  • 55
    • 75749091133 scopus 로고    scopus 로고
    • Microfluidic isolation and transcriptome analysis of serum microvesicles
    • Chen C, Skog J, Hsu CH, et al. Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip 2010; 10:505-511.
    • (2010) Lab Chip , vol.10 , pp. 505-511
    • Chen, C.1    Skog, J.2    Hsu, C.H.3
  • 56
    • 84887122461 scopus 로고    scopus 로고
    • The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF comples
    • Prenser JR, Iyer MK, Sahu A, et al. The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF comples. Nat Genet 2013; 45:1392-1398.
    • (2013) Nat Genet , vol.45 , pp. 1392-1398
    • Prenser, J.R.1    Iyer, M.K.2    Sahu, A.3
  • 57
    • 84896524997 scopus 로고    scopus 로고
    • PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer
    • in press
    • Prensner JR, Chen W, Iyer MK, et al. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. Cancer Res 2014; in press.
    • (2014) Cancer Res
    • Prensner, J.R.1    Chen, W.2    Iyer, M.K.3
  • 58
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a prometastatic phenotype through MET
    • Peinado H, Aleckovic M, Lavotshkin S, et al. Melanoma exosomes educate bone marrow progenitor cells toward a prometastatic phenotype through MET. Nat Med 2012; 18:883-891.
    • (2012) Nat Med , vol.18 , pp. 883-891
    • Peinado, H.1    Aleckovic, M.2    Lavotshkin, S.3
  • 59
    • 67349142591 scopus 로고    scopus 로고
    • Prostate cancer-derived urine exosomes: A novel approach to biomarkers for prostate cancer
    • Nilsson J, Skog J, Nordstrand A, et al. Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer. Br J Cancer 2009; 100:1603-1607.
    • (2009) Br J Cancer , vol.100 , pp. 1603-1607
    • Nilsson, J.1    Skog, J.2    Nordstrand, A.3
  • 60
    • 58149165081 scopus 로고    scopus 로고
    • Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer
    • De Bono JS, Scher HI, Montgomery RB, et al. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res 2008; 14:6302-6309.
    • (2008) Clin Cancer Res , vol.14 , pp. 6302-6309
    • De Bono, J.S.1    Scher, H.I.2    Montgomery, R.B.3
  • 61
    • 84874578095 scopus 로고    scopus 로고
    • Isolation and characterization of circulating tumor cells in prostate cancer
    • Diamond E, Lee GY, Akhtar NH, et al. Isolation and characterization of circulating tumor cells in prostate cancer. Front Oncol 2012; 2: 131.
    • (2012) Front Oncol , vol.2 , pp. 131
    • Diamond, E.1    Lee, G.Y.2    Akhtar, N.H.3
  • 62
    • 84889762593 scopus 로고    scopus 로고
    • Circulating tumor cells in prostate cancer
    • Hu B, Rochefort H, Goldkorn A. Circulating tumor cells in prostate cancer. Cancer 2013; 5:1676-1690.
    • (2013) Cancer , vol.5 , pp. 1676-1690
    • Hu, B.1    Rochefort, H.2    Goldkorn, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.