Cardiovascular morbidity and mortality in surgically treated hyperthyroidism - A nation-wide cohort study with a long-term follow-up

Clinical Endocrinology

Volumn 80, Issue 5, 2014, Pages 743-750

  Ryödi, Essi ^a,b   Salmi, Jorma ^a   Jaatinen, Pia ^a,b   Huhtala, Heini ^b   Saaristo, Rauni ^a   Välimäki, Matti ^c   Auvinen, Anssi ^b   Metso, Saara ^a,b  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE HEART INFARCTION; ADULT; ARTERY DISEASE; ARTICLE; CARDIOMYOPATHY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CEREBROVASCULAR DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; FOLLOW UP; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART FAILURE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; HYPERTENSION; HYPERTHYROIDISM; ISCHEMIC HEART DISEASE; LUNG CIRCULATION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; OPERATION DURATION; PRIORITY JOURNAL; PULMONARY VASCULAR DISEASE; RISK ASSESSMENT; SUBCLINICAL HYPERTHYROIDISM; SUBTOTAL THYROIDECTOMY; THYROIDECTOMY; VALVULAR HEART DISEASE; VEIN DISEASE; CARDIOVASCULAR DISEASES; COMPLICATION; FINLAND; MIDDLE AGED; MORTALITY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; REFERENCE VALUE; REGISTER; RISK FACTOR; TREATMENT OUTCOME;

ADULT; CARDIOVASCULAR DISEASES; COHORT STUDIES; FEMALE; FINLAND; FOLLOW-UP STUDIES; HOSPITALIZATION; HUMANS; HYPERTHYROIDISM; MALE; MIDDLE AGED; PATIENT ADMISSION; PROPORTIONAL HAZARDS MODELS; REFERENCE VALUES; REGISTRIES; RISK FACTORS; THYROIDECTOMY; TREATMENT OUTCOME;

EID: 84898539443     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12359     Document Type: Article

References (35)

1. Bjoro, T., Holmen, J., Kruger, O., et al,. (2000) Prevalence of thyroid disease, thyroid dysfunction and thyroid peroxidase antibodies in a large, unselected population. The Health Study of Nord-Trondelag (HUNT). European Journal of Endocrinology, 143, 639-647.
2. Cooper, D.S., (2003) Hyperthyroidism. Lancet, 362, 459-468.
3. Klementschitsch, P., Shen, K.L., &, Kaplan, E.L., (1979) Reemergence of thyroidectomy as treatment for Graves' disease. Surgical Clinics of North America, 59, 35-44.
4. Weber, K.J., Solorzano, C.C., Lee, J.K., et al,. (2006) Thyroidectomy remains an effective treatment option for Graves' disease. The American Journal of Surgery, 191, 400-405.
5. Winsa, B., Rastad, J., Akerstrom, G., et al,. (1995) Retrospective evaluation of subtotal and total thyroidectomy in Graves' disease with and without endocrine ophthalmopathy. European Journal of Endocrinology, 132, 406-412.
6. Sosa, J.A., Bowman, H.M., Tielsch, J.M., et al,. (1998) The importance of surgeon experience for clinical and economic outcomes from thyroidectomy. Annals of Surgery, 228, 320-330.
7. Gaujoux, S., Leenhardt, L., Tresallet, C., et al,. (2006) Extensive thyroidectomy in Graves' disease. Journal of the American Collegues of Surgeons, 202, 868-873.
8. Metso, S., Auvinen, A., Salmi, J., et al,. (2008) Increased long-term cardiovascular morbidity among patients treated with radioactive iodine for hyperthyroidism. Clinical Endocrinology, 68, 450-457.
9. Franklyn, J.A., Maisonneuve, P., Sheppard, M.C., et al,. (1998) Mortality after the treatment of hyperthyroidism with radioactive iodine. The New England Journal of Medicine, 338, 712-718.
10. Franklyn, J.A., Sheppard, M.C., &, Maisonneuve, P., (2005) Thyroid function and mortality in patients treated for hyperthyroidism. The Journal of American Medical Association, 294, 71-80.
11. Hall, P., Lundell, G., &, Holm, L.E., (1993) Mortality in patients treated for hyperthyroidism with iodine-131. Acta Endocrinologica, 128, 230-234.
12. Metso, S., Jaatinen, P., Huhtala, H., et al,. (2007) Increased cardiovascular and cancer mortality after radioiodine treatment for hyperthyroidism. The Journal of Clinical Endocrinology and Metabolism, 92, 2190-2196.
13. Osman, F., Franklyn, J.A., Holder, R.L., et al,. (2007) Cardiovascular manifestations of hyperthyroidism before and after antithyroid therapy: a matched case-control study. Journal of the American College of Cardiology, 49, 71-81.
14. Boelaert, K., Maisonneuve, P., Torlinska, B., et al,. (2013) Comparison of mortality in hyperthyroidism during periods of treatment with thionamides and after radioiodine. The Journal of Clinical Endocrinology & Metabolism, 98, 1869-1882.
15. Sund, R., (2012) Quality of the Finnish Hospital Discharge Register: a systematic review. Scandinavian Journal of Public Health, 40, 505-515.
16. Holm, L.E., Hall, P., Wiklund, K.l., et al,. (1991) Cancer risk after iodine-131 therapy for hyperthyroidism. Journal of National Cancer Institute, 83, 1072-1077.
17. Franklyn, J.A., Daykin, J., Drolc, Z., et al,. (1991) Long-term follow-up of treatment of thyrotoxicosis by three different methods. Clinical Endocrinology, 34, 71-76.
18. Palit, T.K., Miller, C.C. 3rd, &, Miltenburg, D.M., (2000) The efficacy of thyroidectomy for Graves' disease: a meta-analysis. Journal of Surgical Research, 90, 161-165.
19. Brandt, F., Green, A., Hegedus, L., et al,. (2011) A critical review and meta-analysis of the association between overt hyperthyroidism and mortality. European Journal of Endocrinology, 165, 491-497.
20. Klein, I., (1988) Thyroxine-induced cardiac hypertrophy: time course of development and inhibition by propranolol. Endocrinology, 123, 203-210.
21. Levy, D., Garrison, R.J., Savage, D.D., et al,. (1990) Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. The New England Journal of Medicine, 322, 1561-1566.
22. Klein, I., &, Ojamaa, K., (2001) Thyroid hormone and the cardiovascular system. The New England Journal of Medicine, 344, 501-509.
23. Cai, Y., Ren, Y., &, Shi, J., (2011) Blood pressure levels in patients with subclinical thyroid dysfunction: a meta-analysis of cross-sectional data. Hypertension Research, 34, 1098-1105.
24. Flynn, R.W., Macdonald, T.M., Jung, R.T., et al,. (2006) Mortality and vascular outcomes in patients treated for thyroid dysfunction. The Journal of Clinical Endocrinology and Metabolism, 91, 2159-2164.
25. Selmer, C., Olesen, J.B., Hansen, M.L., et al,. (2012) The spectrum of thyroid disease and risk of new onset atrial fibrillation: a large population cohort study. British Medical Journal, 345, e7895.
26. Komiya, N., Isomoto, S., Nakao, K., et al,. (2002) Electrophysiological abnormalities of the atrial muscle in patients with paroxysmal atrial fibrillation associated with hyperthyroidism. Clinical Endocrinology, 56, 39-44.
27. Wustmann, K., Kucera, J.P., Zanchi, A., et al,. (2008) Activation of electrical triggers of atrial fibrillation in hyperthyroidism. The Journal of Clinical Endocrinology and Metabolism, 93, 2104-2108.
28. Wijffels, M.C., Kirchhof, C.J., Dorland, R., et al,. (1995) Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats. Circulation, 92, 1954-1968.
29. Sparks, P.B., Mond, H.G., Vohra, J.K., et al,. (1999) Mechanical remodeling of the left atrium after loss of atrioventricular synchrony. A long-term study in humans. Circulation, 100, 1714-1721.
30. Burstein, B., &, Nattel, S., (2008) Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation. Journal of the American College of Cardiology, 51, 802-809.
31. Nattel, S., Li, D., &, Yue, L., (2000) Basic mechanisms of atrial fibrillation-very new insights into very old ideas. Annual Review of Physiology, 62, 51-77.
32. Heliovaara, M., Reunanen, A., Aromaa, A., et al,. (1984) Validity of hospital discharge data in a prospective epidemiological study on stroke and myocardial infarction. Acta Medica Scandinavica, 216, 309-315.
33. Rapola, J.M., Virtamo, J., Korhonen, P., et al,. (1997) Validity of diagnoses of major coronary events in national registers of hospital diagnoses and deaths in Finland. European Journal of Epidemiology, 13, 133-138.
34. Vestergaard, P., (2002) Smoking and thyroid disorders -a meta-analysis. European Journal of Endocrinology, 146, 153-161.
35. Brandt, F., Almind, D., Christensen, K., et al,. (2012) Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons. The Journal of Clinical Endocrinology and Metabolism, 97, 4123-4129.