The spectrum of thyroid disease and risk of new onset atrial fibrillation: A large population cohort study

BMJ (Online)

Volumn 345, Issue 7885, 2012, Pages

  Selmer, Christian ^a   Olesen, Jonas Bjerring ^a   Hansen, Morten Lock ^a   Lindhardsen, Jesper ^a   Olsen, Anne Marie Schjerning ^a   Madsen, Jesper Clausager ^b   Faber, Jens ^a,c   Hansen, Peter Riis ^a   Pedersen, Ole Dyg ^d   Torp Pedersen, Christian ^a,c   Gislason, Gunnar Hilmar ^a  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b Copenhagen General Practitioners Laboratory ^*  (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d ROSKILDE HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

THYROTROPIN; THYROXINE;

ADULT; AGE; ARTICLE; ATTRIBUTABLE RISK; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; DENMARK; DISEASE ASSOCIATION; DISEASE REGISTRY; EUTHYROIDISM; FEMALE; GENERAL PRACTICE; GENERAL PRACTITIONER; HEART ATRIUM FIBRILLATION; HUMAN; HYPERTHYROIDISM; HYPOTHYROIDISM; INCIDENCE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; REGRESSION ANALYSIS; RISK ASSESSMENT; SEX RATIO; THYROID FUNCTION TEST;

ATRIAL FIBRILLATION; DENMARK; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; POPULATION SURVEILLANCE; REGISTRIES; RETROSPECTIVE STUDIES; RISK FACTORS; THYROID DISEASES;

EID: 84870487294     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.e7895     Document Type: Article

References (40)

1. Biondi B, Palmieri EA, Fazio S, Cosco C, Nocera M, Saccà L, et al. Endogenous subclinical hyperthyroidism affects quality of life and cardiac morphology and function in young and middle-aged patients. J Clin Endocrinol Metab 2000;85:4701-05. (Pubitemid 32157655)
2. Faber J, Wiinberg N, Schifter S, Mehlsen J. Haemodynamic changes following treatment of subclinical and overt hyperthyroidism. Eur J Endocrinol 2001;145:391-6. (Pubitemid 32927063)
3. Collet TH, Gussekloo J, Bauer DC, den Elzen WP, Cappola AR, Balmer P, et al. Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med 2012;172:799-809.
4. Gammage MD, Parle JV, Holder RL, Roberts LM, Hobbs FD, Wilson S, et al. Association between serum free thyroxine concentration and atrial fibrillation. Arch Intern Med 2007;167:928-34. (Pubitemid 46762755)
5. Heeringa J, Hoogendoorn EH, van der Deure WM, Hofman A, Peeters RP, Hop WC, et al. High-normal thyroid function and risk of atrial fibrillation: the Rotterdam study. Arch Intern Med 2008;168:2219-24.
6. Sawin CT, Geller A, Wolf PA, Belanger AJ, Baker E, Bacharach P, et al. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med 1994;331:1249-52. (Pubitemid 24333188)
7. Cappola AR, Fried LP, Arnold AM, Danese MD, Kuller LH, Burke GL, et al. Thyroid status, cardiovascular risk, and mortality in older adults. JAMA 2006;295:1033-41.
8. Parle JV, Franklyn JA, Cross KW, Jones SC, Sheppard MC. Prevalence and follow-up of abnormal thyrotrophin (TSH) concentrations in the elderly in the United Kingdom. Clin Endocrinol 1991;34:77-83.
9. Klein I, Ojamaa K. Thyroid hormone and the cardiovascular system. N Engl J Med 2001;344:501-9. (Pubitemid 32164903)
10. Kahaly GJ. Cardiovascular and atherogenic aspects of subclinical hypothyroidism. Thyroid 2000;10:665-79.
11. Fazio S, Biondi B, Carella C, Sabatini D, Cittadini A, Panza N, et al. Diastolic dysfunction in patients on thyroid-stimulating hormone suppressive therapy with levothyroxine: beneficial effect of beta-blockade. J Clin Endocrinol Metab 1995;80:2222-6.
12. Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA, et al. Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 2002;87:489-99. (Pubitemid 34158210)
13. Pedersen CB. The Danish Civil Registration System. Scand J Public Health 2011;39(7 suppl):22-5.
14. Lynge E, Sandegaard JL, Rebolj M. The Danish National Patient Register. Scand J Public Health 2011;39(7 suppl):30-3.
15. WHO Collaborating Centre for Drug Statistics Methodology. Guidelines for ATC classification and DDD assignment, 2012 . www.whocc.no/atc-ddd-publications/ guidelines/.
16. Kildemoes HW, Sørensen HT, Hallas J. The Danish National Prescription Registry. Scand J Public Health 2011;39(7 suppl):38-41.
17. Helweg-Larsen K. The Danish Register of Causes of Death. Scand J Public Health 2011;39(7 suppl):26-9.
18. Baadsgaard M, Quitzau J. Danish registers on personal income and transfer payments. Scand J Public Health 2011;39(7 suppl):103-5.
19. Madsen M, Davidsen M, Rasmussen S, Abildstrom SZ, Osler M. The validity of the diagnosis of acute myocardial infarction in routine statistics: a comparison of mortality and hospital discharge data with the Danish MONICA registry. J Clin Epidemiol 2003;56:124-30. (Pubitemid 36315938)
20. Krarup LH, Boysen G, Janjua H, Prescott E, Truelsen T. Validity of stroke diagnoses in a National Register of Patients. Neuroepidemiology 2007;28:150-4. (Pubitemid 47344336)
21. Nuttall M, van der Meulen J, Emberton M. Charlson scores based on ICD-10 administrative data were valid in assessing comorbidity in patients undergoing urological cancer surgery. J Clin Epidemiol 2006;59:265-73. (Pubitemid 43243652)
22. Thygesen SK, Christiansen CF, Christensen S, Lash TL, Sørensen HT. The predictive value of ICD-10 diagnostic coding used to assess Charlson comorbidity index conditions in the population-based Danish National Registry of Patients. BMC Med Res Methodol 2011;11:83.
23. Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 1999
24. Satagopan JM, Ben-Porat L, Berwick M, Robson M, Kutler D, Auerbach AD. A note on competing risks in survival data analysis. Br J Cancer 2004;91:1229-35. (Pubitemid 39424779)
25. Benjamin EJ, Levy D, Vaziri SM, D'Agostino RB, Belanger AJ, Wolf PA. Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study. JAMA 1994;271:840-4.
26. Ladenson PW, Kristensen JD, Ridgway EC, Olsson AG, Carlsson B, Klein I, et al. Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia. N Engl J Med 2010;362:906-16.
27. Collet TH, Gussekloo J, Bauer DC, den Elzen WP, Cappola AR, Balmer P, et al. Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med 2012;172:799-809.
28. Asvold BO, Vatten LJ, Midthjell K, Bjøro T. Serum TSH within the reference range as a predictor of future hypothyroidism and hyperthyroidism: 11-year follow-up of the HUNT Study in Norway. J Clin Endocrinol Metab 2012;97:93-9.
29. Goichot B, Sapin R, Schlienger JL. Subclinical hyperthyroidism: considerations in defining the lower limit of the thyrotropin reference interval. Clin Chem 2009;55:420-4.
30. Buffenstein R, Pinto M. Endocrine function in naturally long-living small mammals. Mol Cell Endocrinol 2009;299:101-11.
31. Atzmon G, Barzilai N, Hollowell JG, Surks MI, Gabriely I. Extreme longevity is associated with increased serum thyrotropin. J Clin Endocrinol Metab 2009;94:1251-4.
32. Jensen MT, Marott JL, Allin KH, Nordestgaard BG, Jensen GB. Resting heart rate is associated with cardiovascular and all-cause mortality after adjusting for inflammatory markers: the Copenhagen City Heart Study. Eur J Prev Cardiol 2012;19:102-8.
33. Biondi B, Palmieri EA, Lombardi G, Fazio S. Effects of subclinical thyroid dysfunction on the heart. Ann Intern Med 2002;137:904-14. (Pubitemid 35416626)
34. Sgarbi JA, Villaça FG, Garbeline B, Villar HE, Romaldini JH. The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities. J Clin Endocrinol Metab 2003;88:1672-7. (Pubitemid 36623386)
35. Zhou Z-H, Ma L-L, Wang L-X. Risk factors for persistent atrial fibrillation following successful hyperthyroidism treatment with radioiodine therapy. Intern Med 2011;50:2947-51.
36. Cooper DS. Clinical practice. Subclinical hypothyroidism. N Engl J Med 2001;345:260-5.
37. Biondi B, Kahaly GJ. Cardiovascular involvement in patients with different causes of hyperthyroidism. Nat Rev Endocrinol 2010;6:431-43.
38. Frost L, Andersen LV, Vestergaard P, Husted S, Mortensen LS. Trend in mortality after stroke with atrial fibrillation. Am J Med 2007;120:47-53. (Pubitemid 46026972)
39. Mukamal KJ, Tolstrup JS, Friberg J, Jensen G, Grønbaek M. Alcohol consumption and risk of atrial fibrillation in men and women: the Copenhagen City Heart Study. Circulation 2005;112:1736-42. (Pubitemid 41368149)
40. Frost L, Vestergaard P. Alcohol and risk of atrial fibrillation or flutter: a cohort study. Arch Intern Med 2004;164:1993-8. (Pubitemid 39390555)