Inactivation of mTor arrests bovine oocytes in the metaphase-I stage, despite reversible inhibition of 4E-BP1 phosphorylation

Molecular Reproduction and Development

Volumn 81, Issue 4, 2014, Pages 363-375

  Mayer, Sophia ^a   Wrenzycki, Christine ^b   Tomek, Wolfgang ^b,c  

^a BVN Neustadt/Aisch ^*  (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE; INITIATION FACTOR 4E BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4E BINDING PROTEIN 2; INITIATION FACTOR 4E BINDING PROTEIN 3; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN KINASE C; TORIN 2; UNCLASSIFIED DRUG; 9-(6-AMINOPYRIDIN-3-YL)-1-(3-(TRIFLUOROMETHYL)PHENYL)BENZO(H)(1,6)NAPHTHYRIDIN-2(1H)-ONE; CARRIER PROTEIN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; NAPHTHYRIDINE DERIVATIVE; PHOSPHOPROTEIN; PHOSPHOTHREONINE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; MEIOSIS; METAPHASE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; ANIMAL; ANTAGONISTS AND INHIBITORS; BOVINAE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENZYME ACTIVE SITE; ENZYMOLOGY; FEMALE; IN VITRO OOCYTE MATURATION; OOCYTE DEVELOPMENT; PHOSPHORYLATION; PHYSIOLOGY;

ATAXIA TELANGIECTASIA; BOVINAE; EUKARYOTA; MAMMALIA; SUS;

ANIMALS; CARRIER PROTEINS; CATALYTIC DOMAIN; CATTLE; CELLS, CULTURED; FEMALE; IN VITRO OOCYTE MATURATION TECHNIQUES; MEIOSIS; METAPHASE; MULTIPROTEIN COMPLEXES; NAPHTHYRIDINES; OOCYTES; OOGENESIS; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTHREONINE; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; TOR SERINE-THREONINE KINASES;

EID: 84898494025     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.22305     Document Type: Article

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