Noninvasive delivery of siRNA and plasmid DNA into skin by fractional ablation: Erbium:YAG laser versus CO2 laser

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 86, Issue 3, 2014, Pages 315-323

  Lee, Woan Ruoh ^a,b   Shen, Shing Chuan ^a   Chen, Wei Yu ^c,d   Aljuffali, Ibrahim A ^e   Suen, Shih Yun ^a,f   Fang, Jia You ^f,g,h  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e KING SAUD UNIVERSITY   (Saudi Arabia)

^f CHANG GUNG UNIVERSITY   (Taiwan)

^g CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^h CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Er:YAG laser; Fractional ablation; Plasmid DNA; siRNA; Skin

Indexed keywords

CLAUDIN 1; DEXTRAN; PLASMID DNA; SMALL INTERFERING RNA; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBON DIOXIDE LASER; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EPIDERMIS; ERBIUM YAG LASER; FEMALE; FLUORESCENCE MICROSCOPY; GENE TARGETING; HAIR FOLLICLE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LASER SURGERY; MACROMOLECULE; MOLECULAR SIZE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RNA TRANSPORT; SKIN ABSORPTION; SKIN PERMEABILITY; SKIN STRUCTURE; SKINFOLD THICKNESS; ADMINISTRATION AND DOSAGE; ANIMAL; COMPARATIVE STUDY; GAS LASER; GENE TRANSFER; LOW LEVEL LASER THERAPY; METABOLISM; NUDE MOUSE; PHYSIOLOGY; PLASMID; PROCEDURES; SOLID STATE LASER; STANDARDS;

ANIMALS; FEMALE; GENE TRANSFER TECHNIQUES; LASER THERAPY; LASERS, GAS; LASERS, SOLID-STATE; MICE; MICE, NUDE; PLASMIDS; RNA, SMALL INTERFERING; SKIN ABSORPTION;

EID: 84898427026     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.08.006     Document Type: Article

References (49)

1. E. Gonzalez-Gonzalez, H. Ra, R.P. Hickerson, Q. Wang, W. Piyawattanametha, M.J. Mandella, G.S. Kino, D. Leake, A.A. Avilion, O. Solgaard, T.C. Doyle, C.H. Contag, and R.L. Kaspar SiRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model Gene Ther. 16 2009 963 972
2. M.C. Yeh, C.C. Lin, Y.L. Chen, S.S. Huang, H.J. Yang, C.P. Chang, H.Y. Lei, and M.D. Lai A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA Clin. Cancer Res. 15 2009 641 649
3. G.B. Jacobson, E. Gonzalez-Gonzalez, R. Spitler, R. Shinde, D. Leake, R.L. Kaspar, C.H. Contag, and R.N. Zare Biodegradable nanoparticles with sustained release of functional siRNA in skin J. Pharm. Sci. 99 2010 4261 4266
4. B.G. Jung, S.J. Cho, J.H. Ko, and B.J. Lee Inhibitory effects of interleukin-10 plasmid DNA on the development of atopic dermatitis-like skin lesions in NC/Nga mice J. Vet. Sci. 11 2010 213 220
5. T. Hsu, and S. Mitragotri Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer Proc. Natl. Acad. Sci. USA 108 2011 15816 15821
6. W.R. Lee, S.C. Shen, C.J. Liu, C.L. Fang, C.H. Hu, and J.Y. Fang Erbium:YAG laser-mediated oligonucleotide and DNA delivery via the skin: an animal study J. Control. Release 115 2006 344 353
7. W.R. Lee, T.L. Pan, P.W. Wang, R.Z. Zhuo, C.M. Huang, and J.Y. Fang Erbium:YAG laser enhances transdermal peptide delivery and skin vaccination J. Control. Release 128 2008 200 208
8. S.C. Shen, W.R. Lee, Y.P. Fang, C.H. Hu, and J.Y. Fang In vitro percutaneous absorption and in vivo protoporphyrin IX accumulation in skin and tumors after topical 5-aminolevulinic acid application with enhancement using an erbium:YAG laser J. Pharm. Sci. 95 2006 929 938
9. W.R. Lee, S.C. Shen, M.H. Pai, H.H. Yang, C.Y. Yuan, and J.Y. Fang Fractional laser as a tool to enhance the skin permeation of 5-aminolevulinic acid with minimal skin disruption: a comparison with conventional erbium:YAG laser J. Control. Release 145 2010 124 133
10. W.R. Lee, S.C. Shen, S.A. Al-Suwayeh, H.H. Yang, Y.C. Li, and J.Y. Fang Skin permeation of small-molecule drugs, macromolecules, and nanoparticles mediated by a fractional carbon dioxide laser: the role of hair follicles Pharm. Res. 30 2013 792 802
11. 2 laser resurfacing: the best fluences through a clinical, histological, and ultrastructural evaluation J. Cosmet. Dermatol. 10 2011 210 216
12. S.G. Kim, E.Y. Kim, Y.J. Kim, and S.I. Lee The efficacy and safety of ablative fractional resurfacing using a 2940-nm Er:YAG laser for traumatic scars in the early posttraumatic period Arch. Plast. Surg. 39 2012 232 237
13. J.H. Ko, B.G. Jung, Y.S. Park, and B.J. Lee Inhibitory effects of interferon-gamma plasmid DNA on DMBA-TPA induced mouse skin carcinogenesis Cancer Gene Ther. 18 2011 646 654
14. W.R. Lee, S.C. Shen, R.Z. Zhuo, K.C. Wang, and J.Y. Fang Enhancement of topical small interfering RNA delivery and expression by low-fluence erbium:YAG laser pretreatment of skin Hum. Gene Ther. 20 2009 580 588
15. A. Teichmann, U. Jacobi, M. Ossadnik, H. Richter, S. Koch, W. Sterry, and J. Lademann Differential stripping: determination of the amount of topically applied substances penetrated into the hair follicles J. Invest. Dermatol. 125 2005 264 269
16. S.A. Leachman, R.P. Hickerson, P.R. Hull, F.J.D. Smith, L.M. Milstone, E.B. Lane, S.J. Bale, D.R. Roop, W.H.I. McLean, and R.L. Kaspar Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenital J. Dermatol. Sci. 51 2008 151 157
17. S.A. Leachman, R.P. Hickerson, M.E. Schwartz, E.E. Bullough, S.L. Hutcherson, K.M. Boucher, C.D. Hansen, M.J. Eliason, G.S. Srivatsa, D.J. Kornbrust, F.J.D. Smith, W.H.I. McLean, L.M. Milstone, and R.L. Kaspar First-in-human mutation-targeted siRNA phase 1b trial of an inherited skin disorder Mol. Ther. 18 2010 442 446
18. N. Yamashita, K. Tachibana, K. Ogawa, N. Tsujita, and A. Tomita Scanning electron microscopic evaluation of the skin surface after ultrasound exposure Anat. Rec. 247 1997 455 461
19. L.W. Zhang, S.A. Al-Suwayeh, P.W. Hsieh, and J.Y. Fang A comparison of skin delivery of ferulic acid and its derivatives: evaluation of their efficacy and safety Int. J. Pharm. 399 2010 44 51
20. K.B. Sloan, and S. Wasdo Designing for topical delivery: prodrugs can make the difference Med. Res. Rev. 23 2003 763 793
21. V.D. Thanik, M.R. Geives, O.Z. Lerman, N. Seiser, W. Dec, C.C. Chang, S.M. Warren, J.P. Levine, and P.B. Saadeh Topical matrix-based siRNA silences local gene expression in a murine wound model Gene Ther. 14 2007 1305 1308
22. Ritprajak, M. Hashiguchi, and M. Azuma Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells Mol. Ther. 16 2008 1323 1330
23. B. Markelc, E. Bellard, G. Sersa, S. Pelofy, J. Teissie, A. Coer, M. Golzio, and M. Cemazar In vivo molecular imaging and histological analysis of changes induced by electric pulses used for plasmid DNA electrotransfer to the skin: a study in a dorsal window chamber in mice J. Membr. Biol. 245 2012 545 554
24. E. Gonzalez-Gonzalez, T.J. Speaker, R.P. Hickerson, R. Spitler, M.A. Flores, D. Leake, C.H. Contag, and R.L. Kaspar Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD) Mol. Ther. 18 2010 1667 1674
25. A.G. Doukas, and N. Kollias Transdermal drug delivery with a pressure wave Adv. Drug Deliv. Rev. 56 2004 559 579
26. X. Chen, D. Shah, G. Kositratna, D. Manstein, R.R. Anderson, and M.X. Wu Facilitation of transcutaneous drug delivery and vaccine immunization by a safe laser technology J. Control. Release 159 2012 43 51
27. S. Lee, D.J. McAuliffe, T.J. Flotte, N. Kollias, and A.G. Doukas Photomechanical transdermal delivery: the effect of laser confinement Lasers Surg. Med. 28 2001 344 347
28. W.R. Lee, S.C. Shen, S.A. Al-Suwayeh, H.H. Yang, C.Y. Yuan, and J.Y. Fang Laser-assisted topical drug delivery by using a low-fluence fractional laser: imiquimod and macromolecules J. Control. Release 153 2011 240 248
29. 2 laser skin rejuvenation Dermatol. Ther. 24 2011 41 53
30. Y.G. Bachhav, S. Summer, A. Heinrich, T. Bragagna, C. Böhler, and Y.N. Kalia Effect of controlled laser microporation on drug transport kinetics into and across the skin J. Control. Release 146 2010 31 36
31. 2 laser-assisted drug delivery Lasers Surg. Med. 42 2010 113 122
32. G. Oni, S.A. Brown, and J.M. Kenkel Can fractional lasers enhance transdermal absorption of topical lidocaine in an in vivo animal model Lasers Surg. Med. 44 2012 168 174
33. Y.K. Lin, S.A. Al-Suwayeh, Y.L. Leu, F.M. Shen, and J.Y. Fang Squalene-containing nanostructured lipid carriers promote percutaneous absorption and hair follicle targeting of diphencyprone for treating alopecia areata Pharm. Res. 30 2013 435 446
34. N. Otberg, H. Richter, H. Schaefer, U. Blume-Peytavi, W. Sterry, and J. Lademann Variations of hair follicle size and distribution in different body sites J. Invest. Dermatol. 122 2004 14 19
35. J.Y. Fang, W.R. Lee, S.C. Shen, H.Y. Wang, C.L. Fang, and C.H. Hu Transdermal delivery of macromolecules by erbium:YAG laser J. Control. Release 100 2004 75 85
36. J. Shim, H.S. Kang, W.S. Park, S.H. Han, J. Kim, and I.S. Chang Transdermal delivery of minoxidil with block copolymer nanoparticles J. Control. Release 97 2004 477 484
37. S. Trauer, A. Patzelt, N. Otberg, F. Knorr, C. Rozycki, G. Balizs, R. Büttemeyer, M. Linscheid, M. Liebsch, and J. Lademann Permeation of topically applied caffeine through human skin - a comparison of in vivo and in vitro data Br. J. Clin. Pharmacol. 68 2009 181 186
38. S. Lee, D.J. McAuliffe, N. Kollias, T.J. Flotte, and A.G. Doukas Permeabilization and recovery of the stratum corneum in vivo: the synergy of photomechanical waves and sodium lauryl sulfate Lasers Surg. Med. 29 2001 145 150
39. M. Jiang, C.P. Rubbi, and J. Milner Gel-based application of siRNA to human epithelial cancer cells induces RNAi-dependent apoptosis Oligonucleotides 14 2004 239 248
40. B. Geusens, N. Sanders, T. Prow, M. Van Gele, and J. Lambert Cutaneous short-interferring RNA therapy Expert Opin. Drug Deliv. 6 2009 1333 1349
41. S. Sato, T. Ando, and M. Obara Optical fiber-based photomechanical gene transfer system for in vivo application Opt. Lett. 36 2011 4545 4547
42. C.M. Huang, C.C. Wang, M. Kawai, S. Barnes, and C.A. Elmets Surfactant sodium lauryl sulfate enhances skin vaccination Mol. Cell. Proteom. 5 2006 523 532
43. T. Yamamoto, M. Kurasawa, T. Hattori, T. Maeda, H. Nakano, and H. Sasaki Relationship between expression of tight junction-related molecules and perturbed epidermal barrier function in UVB-irradiated hairless mice Arch. Dermatol. Res. 300 2008 61 68
44. K.S. Liu, K.C. Sung, S.A. Al-Suwayeh, M.C. Ku, C.C. Chu, J.J. Wang, and J.Y. Fang Enhancement of transdermal apomorphine delivery with a diester prodrug strategy Eur. J. Pharm. Biopharm. 78 2011 422 431
45. C.M. Niessen Tight junctions/adherins junctions: basic structure and function J. Invest. Dermatol. 127 2007 2525 2532
46. J.M. Brandner, M. Haftek, and C.M. Niessen Adherens junctions, desmosomes and tight junctions in epidermal barrier function Open Dermatol. J. 4 2010 14 20
47. T. Maretzky, F. Scholz, B. Köten, E. Proksch, P. Saftig, and K. Reiss ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis J. Invest. Dermatol. 128 2008 1737 1746
48. R. Darlenski, J. Kazandjieva, and N. Tsankov Skin barrier function: morphological basis and regulatory mechanisms J. Clin. Med. 4 2011 36 45
49. Y.G. Bachhav, A. Heinrich, and Y.N. Kalia Using laser microporation to improve transdermal delivery of diclofenac: increasing bioavailability and the range of therapeutic applications Eur. J. Pharm. Biopharm. 78 2011 408 414