Acellular bi-layer silk fibroin scaffolds support tissue regeneration in a rabbit model of onlay urethroplasty

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Chung, Yeun Goo ^a   Tu, Duong ^a,b   Franck, Debra ^a   Gil, Eun Seok ^c   Algarrahi, Khalid ^a   Adam, Rosalyn M ^a,b   Kaplan, David L ^c   Estrada Jr , Carlos R ^a,b   Mauney, Joshua R ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Tufts University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACELLULAR BILAYER SILK FIBROIN SCAFFOLD; ALPHA SMOOTH MUSCLE ACTIN; CD31 ANTIGEN; CYTOKERATIN; SILK FIBROIN; SYNAPTOPHYSIN; TISSUE SCAFFOLD; TRANSGELIN; UNCLASSIFIED DRUG; BIOMATERIAL; FIBROIN; SILK;

ADULT; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; EOSINOPHIL; IMMUNOGENICITY; INNERVATION; MALE; MONONUCLEAR CELL; NERVE CELL; NONHUMAN; ONLAY URETHROPLASTY; RABBIT; SMALL INTESTINAL SUBMUCOSA IMPLANT; TISSUE REGENERATION; URETHROGRAPHY; URETHROPLASTY; URETHROTOMY; UROLOGICAL IMPLANT; ANIMAL; ANIMAL MODEL; CHEMISTRY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; PATHOLOGY; PLASTIC SURGERY; REGENERATION; SURGERY; TISSUE SCAFFOLD; URETHRA;

ANIMALS; BIOCOMPATIBLE MATERIALS; FIBROINS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MODELS, ANIMAL; RABBITS; RECONSTRUCTIVE SURGICAL PROCEDURES; REGENERATION; SILK; TISSUE SCAFFOLDS; URETHRA;

EID: 84898422244     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091592     Document Type: Article

References (42)

1. Olesen KP, Walter S, Frimodt-Moller C, Hebjorn S, Gammelgaard PA, et al. (1975) Morphology and function of the bladder and urethra in female urinary incontinence. Int Urol Nephrol 7: 303-13.
2. Mawhinney M, Mariotti A (2013) Physiology, pathology and pharmacology of the male reproductive system. Periodontol 2000 61: 232-51. doi: 10.1111/j.1600-0757.2011.00408.x.
3. Macedo A Jr, Rondon A, Ortiz V (2012) Hypospadias. Curr Opin Urol 22: 447-52. doi: 10.1097/MOU.0b013e328357bc62.
4. Lee YJ, Kim SW (2013) Current Management of Urethral Stricture. Korean J Urol 54: 561-9.
5. Bhatnagar A, Upadhyaya VD, Kumar B (2012) Congenital urethrocutaneous fistula: Case report with review of literature. Indian J Plast Surg 45: 563-5. doi:10.4103/0970-0358.105979.
6. Siosaki MD, Machado RD, Souza AT, Magnabosco WJ, Santos AC, et al. (2013) Primary proximal urethral adenocarcinoma: Case report and brief review. Can Urol Assoc J 7: E499-501. doi: 10.5489/cuaj.399.
7. Elgammal MA (2009) Straddle injuries to the bulbar urethra: management and outcome in 53 patients. Int Braz J Urol 35: 450-8.
8. Brandes S (2006) Initial management of anterior and posterior urethral injuries. Urol Clin North Am 33: 87-95, vii.
9. Zinman L (1997) Extragenital muscular myocutaneous and fasciocutaneous flaps in urethral reconstruction. Urol Clin North Am 24: 683-98.
10. Sugita Y, Tanikaze S, Yoshino K, Yamamichi F (2001) Severe hypospadias repair with meatal based paracoronal skin flap: the modified Koyanagi repair. J Urol 166: 1051-3. (Pubitemid 32751041)
11. Kozinn SI, Harty NJ, Zinman L, Buckley JC (2013) Management of Complex Anterior Urethral Strictures With Multistage Buccal Mucosa Graft Reconstruction. Urology 82: 718-23. doi: 10.1016/j.urology.2013.03.081.
12. Monfort G, Bretheau D, Di Benedetto V, Bankole R (1992) Urethral stricture in children: treatment by urethroplasty with bladder mucosa graft. J Urol 148: 1504-6.
13. Marzorati G, Ghinolfi G, Pachera F, Meazza A (2008) Bladder and buccal mucosa graft in urethral stricture reconstruction. Urologia 75: 177-9.
14. Kadian YS, Rattan KN, Singh J, Singh M, Kajal P, et al. (2011) Tunica vaginalis: an aid in hypospadias fistula repair: our experience of 14 cases. Afr J Paediatr Surg 8: 164-7. doi: 10.4103/0189-6725.86054.
15. Cimador M, Vallasciani S, Manzoni G, Rigamonti W, De Grazia E, et al. (2013) Castagnetti M. Failed hypospadias in paediatric patients. Nat Rev Urol [Epub ahead of print]. doi: 10.1038/nrurol.2013.164
16. Meeks JJ, Erickson BA, Granieri MA, Gonzalez CM (2009) Stricture recurrence after urethroplasty: a systematic review. J Urol 182: 1266-70. doi: 10.1016/j.juro.2009.06.027.
17. Finkelstein LH, Blatstein LM (1991) Epilation of hair-bearing urethral grafts using the neodymium:YAG surgical laser. J Urol 146: 840-2.
18. Xie L, Li S, Li Q (2013) Surgical Treatment and Prevention of Recurrence of Urethral Calculi Associated with Hairballs after Urethroplasty. Urol Int 91 [Epub ahead of print]. doi: 10.1159/000353101.
19. Chandrasekharam VV (2013) Single-stage repair of hypospadias using longitudinal dorsal island flap: Single-surgeon experience with 102 cases. Indian J Urol 29: 48-52. doi: 10.4103/0970-1591.109984.
20. Mellon MJ, Bihrle R (2013) Ventral onlay buccal mucosa urethroplasty: A 10-year experience. Int J Urol [Epub ahead of print]. doi: 10.1111/iju.12236.
21. Fu Q, Cao YL (2011) Tissue engineering and stem cell application of urethroplasty: from bench to bedside. Urology 79: 246-53. doi: 10.1016/j.urology.2011.08.043.
22. Palmer BW, Kropp BP (2013) Update on tissue engineering in pediatric urology. Curr Urol Rep 14: 327-32. doi: 10.1007/s11934-013-0329-6.
23. Kropp BP, Ludlow JK, Spicer D, Rippy MK, Badylak SF, et al. (1998) Rabbit urethral regeneration using small intestinal submucosa onlay grafts. Urology 52: 138-42. (Pubitemid 28317947)
24. Chen F, Yoo JJ, Atala A (1999) Acellular collagen matrix as a possible "off the shelf" biomaterial for urethral repair. Urology 54: 407-10. (Pubitemid 29407010)
25. Villoldo GM, Loresi M, Giudice C, Damia O, Moldes JM, et al. (2013) Histologic changes after urethroplasty using small intestinal submucosa unseeded with cells in rabbits with injured urethra. Urology 81: 1380.e1-5.
26. Atala A, Guzman L, Retik AB (1999) A novel inert collagen matrix for hypospadias repair. J Urol 162: 1148-51. (Pubitemid 29434692)
27. El-Kassaby AW, Retik AB, Yoo JJ, Atala A (2003) Urethral stricture repair with an off-the-shelf collagen matrix. J Urol 169: 170-3; discussion 173.
28. Palminteri E, Berdondini E, Colombo F, Austoni E (2007) Small intestinal submucosa (SIS) graft urethroplasty: short-term results. Eur Urol 51: 1695-701; discussion 1701.
29. Hauser S, Bastian PJ, Fechner G, Müller SC (2006) Small intestine submucosa in urethral stricture repair in a consecutive series. Urology 68: 263-6. (Pubitemid 44175529)
30. Palminteri E, Berdondini E, Fusco F, De Nunzio C, Salonia A (2012) Long-term results of small intestinal submucosa graft in bulbar urethral reconstruction. Urology 79: 695-701. doi: 10.1016/j.urology.2011.09.055.
31. Olsen L, Bowald S, Busch C, Carlsten J, Eriksson I (1992) Urethral reconstruction with a new synthetic absorbable device. An experimental study. Scand J Urol Nephrol 26: 323-6. (Pubitemid 23018673)
32. Cilento BG, Retik AB, Atala A (1995) Urethral reconstruction using a polymer mesh. J Urol 153: 371-4.
33. Raya-Rivera A, Esquiliano DR, Yoo JJ, Lopez-Bayghen E, Soker S, et al. (2011) Tissue-engineered autologous urethras for patients who need reconstruction: an observational study. Lancet 377: 1175-82. doi: 10.1016/S0140-6736(10)62354-9.
34. Ceonzo K, Gaynor A, Shaffer L, Kojima K, Vacanti CA, et al. (2006) Polyglycolic acid-induced inflammation: role of hydrolysis and resulting complement activation. Tissue Eng 12: 301-8.
35. Gomez P 3rd, Gil ES, Lovett ML, Rockwood DN, Di Vizio D, et al. (2011) The effect of manipulation of silk scaffold fabrication parameters on matrix performance in a murine model of bladder augmentation. Biomaterials 32: 7562-70. doi:10.1016/j.biomaterials.2011.06.067.
36. Kim UJ, Park J, Kim HJ, Wada M, Kaplan DL (2005) Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin. Biomaterials 26: 2775-85. (Pubitemid 39600730)
37. Rockwood DN, Preda RC, Yücel T, Wang X, Lovett ML, et al. (2011) Materials fabrication from Bombyx mori silk fibroin. Nat Protoc 6: 1612-31. doi: 10.1038/nprot.2011.379.
38. Wang Y, Rudym DD, Walsh A, Abrahamsen L, Kim HJ, et al. (2008) In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials 29: 3415-28. doi: 10.1016/j.biomaterials.2008.05.002.
39. Seth A, Chung YG, Gil ES, Tu D, Franck D, et al. (2013) The performance of silk scaffolds in a rat model of augmentation cystoplasty. Biomaterials 34: 4758-65. doi: 10.1016/j.biomaterials.2013.03.038.
40. Tu DD, Chung YG, Gil ES, Seth A, Franck D, et al. (2013) Bladder tissue regeneration using acellular bi-layer silk scaffolds in a large animal model of augmentation cystoplasty. Biomaterials 34: 8681-9. doi: 10.1016/j.biomaterials. 2013.08.001.
41. Mauney JR, Cannon GM, Lovett ML, Gong EM, Di Vizio D, et al. (2011) Evaluation of gel spun silk-based biomaterials in a murine model of bladder augmentation. Biomaterials 32: 808-18. doi: 10.1016/j.biomaterials.2010.09.051.
42. Sievert KD, Bakircioglu ME, Nunes L, Tu R, Dahiya R, et al. (2000) Homologous acellular matrix graft for urethral reconstruction in the rabbit: histological and functional evaluation. J Urol 163: 1958-65. (Pubitemid 30366794)