The university of new mexico center for molecular discovery

Combinatorial Chemistry and High Throughput Screening

Volumn 17, Issue 3, 2014, Pages 256-265

  Edwards, Bruce S ^a   Gouveia, Kristine ^a   Oprea, Tudor I ^a   Sklar, Larry A ^a  

^a UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

1536 well format; Drug discovery; Drug repurposing; Efflux pumps; GTPases; High throughput flow cytometry; Hypercyt; NMMLSC; Personalized medicine; Phenotypic screening

Indexed keywords

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; BACTERIAL VIRULENCE; CANCER CHEMOTHERAPY; CELL ADHESION; CELL DIFFERENTIATION; CELL POPULATION; CELL SCREENING; CELL SUBPOPULATION; CLINICAL RESEARCH; DRUG REPOSITIONING; DRUG SCREENING; DRUG TARGETING; DRUG TRANSPORT; FLOW CYTOMETER; FLOW CYTOMETRY; FLUORESCENCE; GENE EXPRESSION; HIGH THROUGHPUT FLOW CYTOMETRY; HIGH THROUGHPUT SCREENING; HUMAN; MEDICAL EDUCATION; MEDICAL RESEARCH; NONHUMAN; PERSONALIZED MEDICINE; PRION DISEASE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANSLATIONAL RESEARCH; COMMUNICABLE DISEASES; COMPUTER INTERFACE; DEVICES; DRUG DEVELOPMENT; IMMUNOLOGY; NEOPLASMS; ORGANIZATION AND MANAGEMENT; PROCEDURES; UNITED STATES; UNIVERSITY; WORKFLOW;

ALLERGY AND IMMUNOLOGY; COMMUNICABLE DISEASES; DRUG DISCOVERY; DRUG REPOSITIONING; FLOW CYTOMETRY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INDIVIDUALIZED MEDICINE; NEOPLASMS; NEW MEXICO; TRANSLATIONAL MEDICAL RESEARCH; UNIVERSITIES; USER-COMPUTER INTERFACE; WORKFLOW;

EID: 84898009775     PISSN: 13862073     EISSN: 18755402     Source Type: Journal    
DOI: 10.2174/1386207317666140109123908     Document Type: Article

References (8)

1. Sklar, L.A.; Carter, M.B.; Edwards, B.S. Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening. Curr. Opin. Pharmacol., 2007, 7, 527-534.
2. Edwards, B.S.; Zhu, J.; Chen, J.; Carter, M.B.; Thal, D.M,; Tesmer, J.J.; Graves, S.W.; Sklar, L.A. Cluster cytometry for high-capacity bioanalysis. Cytometry A, 2012, 81, 419-429.
3. Pinilla, C.; Edwards, B.S.; Appel, J.R.; Yates-Gibbins, T.; Giulianotti, M.A.; Medina-Franco, J.L.; Young, S.M.; Santos, R.G.; Sklar, L.A.; Houghten, R.A. Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries. Mol. Pharmacol., 2013, 84, 314-324.
4. Chen, J.; Young, S.M.; Allen, C.; Seeber, A.; Peli-Gulli, M.P.; Panchaud, N.; Waller, A.; Ursu, O.; Yao, T.; Golden, J.E.; Strouse, J.J.; Carter, M.B.; Kang, H.; Bologa, C.G.; Foutz, T.D.; Edwards, B.S.; Peterson, B.R.; Aube, J.; Werner-Washburne, M.; Loewith, R.J.; De Virgilio, C.; Sklar, L.A. Identification of a Small Molecule Yeast TORC1 Inhibitor with a Multiplex Screen Based on Flow Cytometry. ACS Chem. Biol., 2012, 7, 715-722.
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