Overexpression of the NR2A subunit in the forebrain impairs long-term social recognition and non-social olfactory memory

Genes, Brain and Behavior

Volumn 13, Issue 4, 2014, Pages 376-384

  Jacobs, S A ^a   Tsien, J Z ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Long term memory; NMDA; NR2A; NR2B; Social recognition memory

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR2A NMDA RECEPTOR; NR2B NMDA RECEPTOR;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENTORHINAL CORTEX; FEMALE; FOREBRAIN; GENE OVEREXPRESSION; HABITUATION; HYPOTHESIS; LONG TERM MEMORY; LONG TERM POTENTIATION; MALE; NONHUMAN; OLFACTORY MEMORY; PRIORITY JOURNAL; RAT; RECOGNITION; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; GENETICS; METABOLISM; MOUSE; ODOR; PHYSIOLOGY; SEX DIFFERENCE; SOCIAL BEHAVIOR; SPECIES DIFFERENCE;

ANIMALIA; MUS; MUS MUSCULUS; RATTUS; RODENTIA;

ANIMALS; FEMALE; HABITUATION, PSYCHOPHYSIOLOGIC; MALE; MEMORY, LONG-TERM; MICE; MICE, INBRED C57BL; PROSENCEPHALON; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RECOGNITION (PSYCHOLOGY); SEX FACTORS; SMELL; SOCIAL BEHAVIOR; SPECIES SPECIFICITY;

EID: 84897960001     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/gbb.12123     Document Type: Article

References (57)

1. Adolphs, R. (2009) The social brain: neural basis of social knowledge. Annu Rev Psychol 60, 693-716.
2. Anderson, C.N. & Grether, G.F. (2010) Interspecific aggression and character displacement of competitor recognition in Hetaerina damselflies. Proc Biol Sci 277, 549-555.
3. Apfelbach, R., Blanchard, C.D., Blanchard, R.J., Hayes, R.A. & Mcgregor, I.S. (2005) The effects of predator odors in mammalian prey species: a review of field and laboratory studies. Neurosci Biobehav Rev 29, 1123-1144.
4. Boal, J.G. (2006) Social recognition: a top down view of cephalopod behaviour. Vie Milieu Life Environ 56, 69-79.
5. Cao, X., Cui, Z., Feng, R., Tang, Y.P., Qin, Z., Mei, B. & Tsien, J.Z. (2007) Maintenance of superior learning and memory function in NR2B transgenic mice during ageing. Eur J Neurosci 25, 1815-1822.
6. Cheetham, S.A., Thom, M.D., Jury, F., Ollier, W.E., Beynon, R.J. & Hurst, J.L. (2007) The genetic basis of individual-recognition signals in the mouse. Curr Biol 17, 1771-1777.
7. Cui, Z., Feng, R., Jacobs, S., Duan, Y., Wang, H., Cao, X. & Tsien, J.Z. (2013) Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory. Sci Rep 3, 1036.
8. Dahanukar, A. & Ray, A. (2011) Courtship, aggression and avoidance: pheromones, receptors and neurons for social behaviors in Drosophila. Fly (Austin) 5, 58-63.
9. Dantzer, R., Bluthe, R.M., Koob, G.F. & Le Moal, M. (1987) Modulation of social memory in male rats by neurohypophyseal peptides. Psychopharmacology (Berl) 91, 363-368.
10. Dielenberg, R.A. & Mcgregor, I.S. (1999) Habituation of the hiding response to cat odor in rats (Rattus norvegicus). J Comp Psychol 113, 376-387.
11. Dielenberg, R.A. & Mcgregor, I.S. (2001) Defensive behavior in rats towards predatory odors: a review. Neurosci Biobehav Rev 25, 597-609.
12. Dielenberg, R.A., Hunt, G.E. & Mcgregor, I.S. (2001) "When a rat smells a cat": the distribution of Fos immunoreactivity in rat brain following exposure to a predatory odor. Neuroscience 104, 1085-1097.
13. Farine, J.P., Ferveur, J.F. & Everaerts, C. (2012) Volatile Drosophila cuticular pheromones are affected by social but not sexual experience. PLoS One 7, e40396.
14. Ferguson, J.N., Young, L.J. & Insel, T.R. (2002) The neuroendocrine basis of social recognition. Front Neuroendocrinol 23, 200-224.
15. Fett, A.K., Shergill, S.S., Joyce, D.W., Riedl, A., Strobel, M., Gromann, P.M. & Krabbendam, L. (2012) To trust or not to trust: the dynamics of social interaction in psychosis. Brain 135, 976-984.
16. Gabor, C.S., Phan, A., Clipperton-Allen, A.E., Kavaliers, M. & Choleris, E. (2012) Interplay of oxytocin, vasopressin, and sex hormones in the regulation of social recognition. Behav Neurosci 126, 97-109.
17. Gao, X.M., Elmer, G.I., Adams-Huet, B. & Tamminga, C.A. (2009) Social memory in mice: disruption with an NMDA antagonist and attenuation with antipsychotic drugs. Pharmacol Biochem Behav 92, 236-242.
18. Gherardi, F., Aquiloni, L. & Tricarico, E. (2012) Revisiting social recognition systems in invertebrates. Anim Cogn 15, 745-762.
19. Groning, J. & Hochkirch, A. (2008) Reproductive interference between animal species. Q Rev Biol 83, 257-282.
20. Guan, X. & Dluzen, D.E. (1994) Age related changes of social memory/recognition in male Fischer 344 rats. Behav Brain Res 61, 87-90.
21. Hazlett, B.A. (1969) "Individual" recognition and agonistic behaviour in Pagurus bernhardus. Nature 222, 268-269.
22. Hlinak, Z. & Krejci, I. (1994) Effects of excitatory amino acid antagonists on social recognition of male rats. Behav Pharmacol 5, 239-244.
23. Hlinak, Z. & Krejci, I. (2002) N-methyl-D-aspartate improved social recognition potency in rats. Neurosci Lett 330, 227-230.
24. Hurst, J.L., Payne, C.E., Nevison, C.M., Marie, A.D., Humphries, R.E., Robertson, D.H., Cavaggioni, A. & Beynon, R.J. (2001) Individual recognition in mice mediated by major urinary proteins. Nature 414, 631-634.
25. Jacobs, S.A. & Tsien, J.Z. (2012) Genetic overexpression of NR2B subunit enhances social recognition memory for different strains and species. PLoS One 7, e36387.
26. Jiang, C.H., Tsien, J.Z., Schultz, P.G. & Hu, Y. (2001) The effects of aging on gene expression in the hypothalamus and cortex of mice. Proc Natl Acad Sci USA 98, 1930-1934.
27. Kogan, J.H., Frankland, P.W. & Silva, A.J. (2000) Long-term memory underlying hippocampus-dependent social recognition in mice. Hippocampus 10, 47-56.
28. Macbeth, A.H., Lee, H.J., Edds, J. & Young, W.S. 3rd (2009) Oxytocin and the oxytocin receptor underlie intrastrain, but not interstrain, social recognition. Genes Brain Behav 8, 558-567.
29. Marashi, V. & Rulicke, T. (2012) The Bruce effect in Norway rats. Biol Reprod 86, 1-5.
30. Menzel, F. & Schmitt, T. (2012) Tolerance requires the right smell: first evidence for interspecific selection on chemical recognition cues. Evolution 66, 896-904.
31. Mody, M., Cao, Y., Cui, Z., Tay, K.Y., Shyong, A., Shimizu, E., Pham, K., Schultz, P., Welsh, D. & Tsien, J.Z. (2001) Genome-wide gene expression profiles of the developing mouse hippocampus. Proc Natl Acad Sci USA 98, 8862-8867.
32. Nakayasu, C., Kanemura, F., Hirano, Y., Shimizu, Y. & Tonosaki, K. (2000) Sensitivity of the olfactory sense declines with the aging in senescence-accelerated mouse (SAM-P1). Physiol Behav 70, 135-139.
33. Noack, J., Richter, K., Laube, G., Haghgoo, H.A., Veh, R.W. & Engelmann, M. (2010) Different importance of the volatile and non-volatile fractions of an olfactory signature for individual social recognition in rats versus mice and short-term versus long-term memory. Neurobiol Learn Mem 94, 568-575.
34. Okamoto, K.W. & Grether, G.F. (2013) The evolution of species recognition in competitive and mating contexts: the relative efficacy of alternative mechanisms of character displacement. Ecol Lett 16, 670-678.
35. Ord, T.J. & Stamps, J.A. (2009) Species identity cues in animal communication. Am Nat 174, 585-593.
36. Petrulis, A., Alvarez, P. & Eichenbaum, H. (2005) Neural correlates of social odor recognition and the representation of individual distinctive social odors within entorhinal cortex and ventral subiculum. Neuroscience 130, 259-274.
37. Philpot, B.D., Weisberg, M.P., Ramos, M.S., Sawtell, N.B., Tang, Y.P., Tsien, J.Z. & Bear, M.F. (2001) Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex. Neuropharmacology 41, 762-770.
38. Prediger, R.D., Batista, L.C. & Takahashi, R.N. (2005) Caffeine reverses age-related deficits in olfactory discrimination and social recognition memory in rats. Involvement of adenosine A1 and A2A receptors. Neurobiol Aging 26, 957-964.
39. Prediger, R.D., De-Mello, N. & Takahashi, R.N. (2006) Pilocarpine improves olfactory discrimination and social recognition memory deficits in 24 month-old rats. Eur J Pharmacol 531, 176-182.
40. Rendall, D., Rodman, P.S. & Emond, R.E. (1996) Vocal recognition of individuals and kin in free-ranging rhesus monkeys. Anim Behav 51, 1007-1015.
41. Richter, K., Wolf, G. & Engelmann, M. (2005) Social recognition memory requires two stages of protein synthesis in mice. Learn Mem 12, 407-413.
42. Roberts, E.K., Lu, A., Bergman, T.J. & Beehner, J.C. (2012) A Bruce effect in wild geladas. Science 335, 1222-1225.
43. Rohrbach, C. (1982) Investigation of the Bruce effect in the Mongolian gerbil (Meriones unguiculatus). J Reprod Fertil 65, 411-417.
44. Sahu, S.C. & Dominic, C.J. (1985) Role of olfactory experience in pheromonal block to implantation (the Bruce effect) in laboratory mice. Indian J Exp Biol 23, 485-489.
45. Staples, L.G., Hunt, G.E., Van Nieuwenhuijzen, P.S. & Mcgregor, I.S. (2008) Rats discriminate individual cats by their odor: possible involvement of the accessory olfactory system. Neurosci Biobehav Rev 32, 1209-1217.
46. Takahashi, L.K., Hubbard, D.T., Lee, I., Dar, Y. & Sipes, S.M. (2007) Predator odor-induced conditioned fear involves the basolateral and medial amygdala. Behav Neurosci 121, 100-110.
47. Tang, Y.P., Shimizu, E., Dube, G.R., Rampon, C., Kerchner, G.A., Zhuo, M., Liu, G. & Tsien, J.Z. (1999) Genetic enhancement of learning and memory in mice. Nature 401, 63-69.
48. Terranova, J.P., Perio, A., Worms, P., Le Fur, G. & Soubrie, P. (1994) Social olfactory recognition in rodents: deterioration with age, cerebral ischaemia and septal lesion. Behav Pharmacol 5, 90-98.
49. Thor, D.H. & Holloway, W.R. (1982) Social Memory of the Male Laboratory Rat. J Comp Physiol Psychol 96, 1000-1006.
50. Tsien, J.Z., Chen, D.F., Gerber, D., Tom, C., Mercer, E.H., Anderson, D.J., Mayford, M., Kandel, E.R. & Tonegawa, S. (1996) Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87, 1317-1326.
51. Van der Staay, F.J., Rutten, K., Erb, C. & Blokland, A. (2011) Effects of the cognition impairer MK-801 on learning and memory in mice and rats. Behav Brain Res 220, 215-229.
52. Wang, D., Cui, Z., Zeng, Q., Kuang, H., Wang, L.P., Tsien, J.Z. & Cao, X. (2009) Genetic enhancement of memory and long-term potentiation but not CA1 long-term depression in NR2B transgenic rats. PLoS One 4, e7486.
53. Weldon, K.B., Taubert, J., Smith, C.L. & Parr, L.A. (2013) How the Thatcher illusion reveals evolutionary differences in the face processing of primates. Anim Cogn 16, 691-700.
54. White, T.L. & Youngentob, S.L. (2004) The effect of NMDA-NR2B receptor subunit over-expression on olfactory memory task performance in the mouse. Brain Res 1021, 1-7.
55. Winslow, J.T. (2003) Mouse social recognition and preference. In Crawley J.N. (ed), Current Protocols in Neuroscience. John Wiley and Sons, Inc. Bethesda, MD, Chapter 8, Unit 8 16.
56. Winslow, J.T. & Camacho, F. (1995) Cholinergic modulation of a decrement in social investigation following repeated contacts between mice. Psychopharmacology (Berl) 121, 164-172.
57. Young, B.J., Otto, T., Fox, G.D. & Eichenbaum, H. (1997) Memory representation within the parahippocampal region. J Neurosci 17, 5183-5195.