메뉴 건너뛰기




Volumn 16, Issue 1, 2014, Pages

A review of Vilazodone, Serotonin, and Major Depressive Disorder

Author keywords

[No Author keywords available]

Indexed keywords

BUSPIRONE; CITALOPRAM; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; PAROXETINE; PINDOLOL; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN 2B RECEPTOR; SERTRALINE; VILAZODONE; ZIMELDINE;

EID: 84897953381     PISSN: 15235998     EISSN: 1555211X     Source Type: Journal    
DOI: 10.4088/PCC.13r01554     Document Type: Review
Times cited : (24)

References (82)
  • 1
    • 76649119764 scopus 로고    scopus 로고
    • Age differences in major depression: Results from the National Comorbidity Survey Replication (NCS-R)
    • PubMed doi:10.1017/S0033291709990213
    • Kessler RC, Birnbaum H, Bromet E, et al. Age differences in major depression: results from the National Comorbidity Survey Replication (NCS-R). Psychol Med. 2010;40(2):225-237. PubMed doi:10.1017/S0033291709990213.
    • (2010) Psychol Med , vol.40 , Issue.2 , pp. 225-237
    • Kessler, R.C.1    Birnbaum, H.2    Bromet, E.3
  • 2
    • 84864852608 scopus 로고    scopus 로고
    • The epidemiology of depression and the evolution of treatment
    • PubMed doi:10.4088/JCP.11096su1c.01
    • Hirschfeld RM. The epidemiology of depression and the evolution of treatment. J Clin Psychiatry. 2012;73(suppl 1):5-9. PubMed doi:10.4088/JCP.11096su1c.01.
    • (2012) J Clin Psychiatry , vol.73 , Issue.SUPPL. 1 , pp. 5-9
    • Hirschfeld, R.M.1
  • 3
    • 84871051576 scopus 로고    scopus 로고
    • Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
    • PubMed doi:10.1016/S0140-6736(12)61729-2
    • Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2163-2196. PubMed doi:10.1016/S0140-6736(12)61729-2.
    • (2012) Lancet , vol.380 , Issue.9859 , pp. 2163-2196
    • Vos, T.1    Flaxman, A.D.2    Naghavi, M.3
  • 4
    • 0042812502 scopus 로고    scopus 로고
    • National patterns of depression treatment in primary care
    • PubMed doi:10.4088/PCC.v02n0603
    • Stafford RS, Ausiello JC, Misra B, et al. National patterns of depression treatment in primary care. Prim Care Companion J Clin Psychiatry. 2000;2(6):211-216. PubMed doi:10.4088/PCC.v02n0603.
    • (2000) Prim Care Companion J Clin Psychiatry , vol.2 , Issue.6 , pp. 211-216
    • Stafford, R.S.1    Ausiello, J.C.2    Misra, B.3
  • 5
    • 84861171954 scopus 로고    scopus 로고
    • Strategies to improve the management of depression in primary care
    • PubMed doi:10.1016/j.pop.2012.03.010
    • Unützer J, Park M. Strategies to improve the management of depression in primary care. Prim Care. 2012;39(2):415-431. PubMed doi:10.1016/j.pop.2012.03.010.
    • (2012) Prim Care , vol.39 , Issue.2 , pp. 415-431
    • Unützer, J.1    Park, M.2
  • 6
    • 85047697923 scopus 로고    scopus 로고
    • Changing profiles of service sectors used for mental health care in the United States
    • PubMed doi:10.1176/appi.ajp.163.7.1187
    • Wang PS, Demler O, Olfson M, et al. Changing profiles of service sectors used for mental health care in the United States. Am J Psychiatry. 2006;163(7):1187-1198. PubMed doi:10.1176/appi.ajp.163.7.1187.
    • (2006) Am J Psychiatry , vol.163 , Issue.7 , pp. 1187-1198
    • Wang, P.S.1    Demler, O.2    Olfson, M.3
  • 7
    • 18144432661 scopus 로고    scopus 로고
    • The National Depressive and Manic-Depressive Association consensus statement on the undertreatment of depression
    • PubMed doi:10.1001/jama.1997.03540280071036
    • Hirschfeld RM, Keller MB, Panico S, et al. The National Depressive and Manic-Depressive Association consensus statement on the undertreatment of depression. JAMA. 1997;277(4):333-340. PubMed doi:10.1001/jama.1997.03540280071036.
    • (1997) JAMA , vol.277 , Issue.4 , pp. 333-340
    • Hirschfeld, R.M.1    Keller, M.B.2    Panico, S.3
  • 8
    • 0011145384 scopus 로고    scopus 로고
    • SSRI antidepressant medications: Adverse effects and tolerability
    • PubMed doi:10.4088/PCC.v03n0105
    • Ferguson JM. SSRI antidepressant medications: adverse effects and tolerability. Prim Care Companion J Clin Psychiatry. 2001;3(1):22-27. PubMed doi:10.4088/PCC.v03n0105.
    • (2001) Prim Care Companion J Clin Psychiatry , vol.3 , Issue.1 , pp. 22-27
    • Ferguson, J.M.1
  • 9
    • 0024407290 scopus 로고
    • Common side effects associated with monoamine oxidase inhibitors
    • PubMed doi:10.1016/0278-5846(89)90137-1
    • Remick RA, Froese C, Keller FD. Common side effects associated with monoamine oxidase inhibitors. Prog Neuropsychopharmacol Biol Psychiatry. 1989;13(3-4):497-504. PubMed doi:10.1016/0278-5846(89)90137-1.
    • (1989) Prog Neuropsychopharmacol Biol Psychiatry , vol.13 , Issue.3-4 , pp. 497-504
    • Remick, R.A.1    Froese, C.2    Keller, F.D.3
  • 10
    • 78650364351 scopus 로고    scopus 로고
    • MAO inhibitors: Risks, benefits, and lore
    • PubMed doi:10.3949/ccjm.77a.09103
    • Wimbiscus M, Kostenko O, Malone D. MAO inhibitors: risks, benefits, and lore. Cleve Clin J Med. 2010;77(12):859-882. PubMed doi:10.3949/ccjm.77a.09103.
    • (2010) Cleve Clin J Med , vol.77 , Issue.12 , pp. 859-882
    • Wimbiscus, M.1    Kostenko, O.2    Malone, D.3
  • 11
    • 84864856634 scopus 로고    scopus 로고
    • Dietary restrictions and drug interactions with monoamine oxidase inhibitors: An update
    • PubMed doi:10.4088/JCP.11096su1c.03
    • Flockhart DA. Dietary restrictions and drug interactions with monoamine oxidase inhibitors: an update. J Clin Psychiatry. 2012;73(suppl 1):17-24. PubMed doi:10.4088/JCP.11096su1c.03.
    • (2012) J Clin Psychiatry , vol.73 , Issue.SUPPL. 1 , pp. 17-24
    • Flockhart, D.A.1
  • 12
    • 69949096626 scopus 로고    scopus 로고
    • Datapoints: Psychotropic drug prescriptions by medical specialty
    • PubMed doi:10.1176/appi.ps.60.9.1167
    • Mark TL, Levit KR, Buck JA. Datapoints: psychotropic drug prescriptions by medical specialty. Psychiatr Serv. 2009;60(9):1167. PubMed doi:10.1176/appi.ps.60.9.1167.
    • (2009) Psychiatr Serv , vol.60 , Issue.9 , pp. 1167
    • Mark, T.L.1    Levit, K.R.2    Buck, J.A.3
  • 13
    • 33846330588 scopus 로고    scopus 로고
    • Effects of different doses of venlafaxine on serotonin and norepinephrine reuptake in healthy volunteers
    • PubMed doi:10.1017/S1461145705006395
    • Blier P, Saint-André E, Hébert C, et al. Effects of different doses of venlafaxine on serotonin and norepinephrine reuptake in healthy volunteers. Int J Neuropsychopharmacol. 2007;10(1):41-50. PubMed doi:10.1017/S1461145705006395.
    • (2007) Int J Neuropsychopharmacol , vol.10 , Issue.1 , pp. 41-50
    • Blier, P.1    Saint-André, E.2    Hébert, C.3
  • 14
    • 26644462876 scopus 로고    scopus 로고
    • SNRIs: Their pharmacology, clinical efficacy, and tolerability in comparison with other classes of antidepressants
    • PubMed
    • Stahl SM, Grady MM, Moret C, et al. SNRIs: their pharmacology, clinical efficacy, and tolerability in comparison with other classes of antidepressants. CNS Spectr. 2005;10(9):732-747. PubMed.
    • (2005) CNS Spectr , vol.10 , Issue.9 , pp. 732-747
    • Stahl, S.M.1    Grady, M.M.2    Moret, C.3
  • 15
    • 70449702726 scopus 로고    scopus 로고
    • Are SNRIs more effective than SSRIs? a review of the current state of the controversy
    • PubMed
    • Thase ME. Are SNRIs more effective than SSRIs? a review of the current state of the controversy. Psychopharmacol Bull. 2008;41(2):58-85. PubMed.
    • (2008) Psychopharmacol Bull , vol.41 , Issue.2 , pp. 58-85
    • Thase, M.E.1
  • 16
    • 56549125124 scopus 로고    scopus 로고
    • Comparative benefits and harms of second-generation antidepressants: Background paper for the American College of Physicians
    • PubMed doi:10.7326/0003-4819-149-10-200811180-00008
    • Gartlehner G, Gaynes BN, Hansen RA, et al. Comparative benefits and harms of second-generation antidepressants: background paper for the American College of Physicians. Ann Intern Med. 2008;149(10):734-750. PubMed doi:10.7326/0003-4819-149-10-200811180-00008.
    • (2008) Ann Intern Med , vol.149 , Issue.10 , pp. 734-750
    • Gartlehner, G.1    Gaynes, B.N.2    Hansen, R.A.3
  • 17
    • 84855343817 scopus 로고    scopus 로고
    • Treating depression after initial treatment failure: Directly comparing switch and augmenting strategies in STAR*D
    • PubMed doi:10.1097/JCP.0b013e31823f705d
    • Gaynes BN, Dusetzina SB, Ellis AR, et al. Treating depression after initial treatment failure: directly comparing switch and augmenting strategies in STAR*D. J Clin Psychopharmacol. 2012;32(1):114-119. PubMed doi:10.1097/JCP.0b013e31823f705d.
    • (2012) J Clin Psychopharmacol , vol.32 , Issue.1 , pp. 114-119
    • Gaynes, B.N.1    Dusetzina, S.B.2    Ellis, A.R.3
  • 18
    • 70149093628 scopus 로고    scopus 로고
    • Escitalopram versus SNRI antidepressants in the acute treatment of major depressive disorder: Integrative analysis of four double-blind, randomized clinical trials
    • PubMed
    • Kornstein SG, Li D, Mao Y, et al. Escitalopram versus SNRI antidepressants in the acute treatment of major depressive disorder: integrative analysis of four double-blind, randomized clinical trials. CNS Spectr. 2009;14(6):326-333. PubMed.
    • (2009) CNS Spectr , vol.14 , Issue.6 , pp. 326-333
    • Kornstein, S.G.1    Li, D.2    Mao, Y.3
  • 19
    • 64249171983 scopus 로고    scopus 로고
    • Escitalopram in the treatment of major depressive disorder: A meta-analysis
    • PubMed doi:10.1185/03007990802622726
    • Kennedy SH, Andersen HF, Thase ME. Escitalopram in the treatment of major depressive disorder: a meta-analysis. Curr Med Res Opin. 2009;25(1):161-175. PubMed doi:10.1185/03007990802622726.
    • (2009) Curr Med Res Opin , vol.25 , Issue.1 , pp. 161-175
    • Kennedy, S.H.1    Andersen, H.F.2    Thase, M.E.3
  • 20
    • 79959572227 scopus 로고    scopus 로고
    • Vilazodone: In major depressive disorder
    • PubMed doi:10.2165/11207550-000000000-00000
    • Frampton JE. Vilazodone: in major depressive disorder. CNS Drugs. 2011;25(7):615-627. PubMed doi:10.2165/11207550-000000000-00000.
    • (2011) CNS Drugs , vol.25 , Issue.7 , pp. 615-627
    • Frampton, J.E.1
  • 21
    • 0014150508 scopus 로고
    • The biochemistry of affective disorders
    • PubMed doi:10.1192/bjp.113.504.1237
    • Coppen A. The biochemistry of affective disorders. Br J Psychiatry. 1967;113(504):1237-1264. PubMed doi:10.1192/bjp.113.504.1237.
    • (1967) Br J Psychiatry , vol.113 , Issue.504 , pp. 1237-1264
    • Coppen, A.1
  • 22
    • 0001139535 scopus 로고
    • Tryptamine metabolism in depression
    • PubMed doi:10.1192/bjp.111.479.993
    • Coppen A, Shaw DM, Malleson A, et al. Tryptamine metabolism in depression. Br J Psychiatry. 1965;111(479):993-998. PubMed doi:10.1192/bjp.111.479.993.
    • (1965) Br J Psychiatry , vol.111 , Issue.479 , pp. 993-998
    • Coppen, A.1    Shaw, D.M.2    Malleson, A.3
  • 23
    • 0000076710 scopus 로고
    • The pharmacology and biochemistry of depression
    • PubMed
    • Prange AJ Jr. The pharmacology and biochemistry of depression. Dis Nerv Syst. 1964;25:217-221. PubMed.
    • (1964) Dis Nerv Syst , vol.25 , pp. 217-221
    • Prange Jr., A.J.1
  • 24
    • 2142822259 scopus 로고    scopus 로고
    • Selectivity of antidepressants: From the monoamine hypothesis of depression to the SSRI revolution and beyond
    • PubMed
    • Owens MJ. Selectivity of antidepressants: from the monoamine hypothesis of depression to the SSRI revolution and beyond. J Clin Psychiatry. 2004;65(suppl 4):5-10. PubMed.
    • (2004) J Clin Psychiatry , vol.65 , Issue.SUPPL. 4 , pp. 5-10
    • Owens, M.J.1
  • 25
    • 0032440963 scopus 로고    scopus 로고
    • Mechanism of action of serotonin selective reuptake inhibitors: Serotonin receptors and pathways mediate therapeutic effects and side effects
    • PubMed doi:10.1016/S0165-0327(98)00221-3
    • Stahl SM. Mechanism of action of serotonin selective reuptake inhibitors: serotonin receptors and pathways mediate therapeutic effects and side effects. J Affect Disord. 1998;51(3):215-235. PubMed doi:10.1016/S0165-0327(98)00221-3.
    • (1998) J Affect Disord , vol.51 , Issue.3 , pp. 215-235
    • Stahl, S.M.1
  • 26
    • 64549158645 scopus 로고    scopus 로고
    • The expanded biology of serotonin
    • PubMed doi:10.1146/annurev.med.60.042307.110802
    • Berger M, Gray JA, Roth BL. The expanded biology of serotonin. Annu Rev Med. 2009;60(1):355-366. PubMed doi:10.1146/annurev.med.60.042307.110802.
    • (2009) Annu Rev Med , vol.60 , Issue.1 , pp. 355-366
    • Berger, M.1    Gray, J.A.2    Roth, B.L.3
  • 27
    • 84867213664 scopus 로고    scopus 로고
    • Depression and hippocampal neurogenesis: A road to remission?
    • PubMed doi:10.1126/science.1222941
    • Eisch AJ, Petrik D. Depression and hippocampal neurogenesis: a road to remission? Science. 2012;338(6103):72-75. PubMed doi:10.1126/science.1222941.
    • (2012) Science , vol.338 , Issue.6103 , pp. 72-75
    • Eisch, A.J.1    Petrik, D.2
  • 28
    • 79952489189 scopus 로고    scopus 로고
    • The role of serotonin receptor subtypes in treating depression: A review of animal studies
    • PubMed doi:10.1007/s00213-010-2097-z
    • Carr GV, Lucki I. The role of serotonin receptor subtypes in treating depression: a review of animal studies. Psychopharmacology (Berl). 2011;213(2-3):265-287. PubMed doi:10.1007/s00213-010-2097-z.
    • (2011) Psychopharmacology (Berl) , vol.213 , Issue.2-3 , pp. 265-287
    • Carr, G.V.1    Lucki, I.2
  • 29
    • 79955860754 scopus 로고    scopus 로고
    • Serotonin receptors-from molecular biology to clinical applications
    • PubMed
    • Pytliak M, Vargová V, Mechírová V, et al. Serotonin receptors-from molecular biology to clinical applications. Physiol Res. 2011;60(1):15-25. PubMed.
    • (2011) Physiol Res , vol.60 , Issue.1 , pp. 15-25
    • Pytliak, M.1    Vargová, V.2    Mechírová, V.3
  • 30
    • 79960087286 scopus 로고    scopus 로고
    • Regulation of dorsal raphe nucleus function by serotonin autoreceptors: A behavioral perspective
    • PubMed doi:10.1016/j.jchemneu.2011.05.001
    • McDevitt RA, Neumaier JF. Regulation of dorsal raphe nucleus function by serotonin autoreceptors: a behavioral perspective. J Chem Neuroanat. 2011;41(4):234-246. PubMed doi:10.1016/j.jchemneu.2011.05.001.
    • (2011) J Chem Neuroanat , vol.41 , Issue.4 , pp. 234-246
    • McDevitt, R.A.1    Neumaier, J.F.2
  • 31
    • 65049083026 scopus 로고    scopus 로고
    • 5-HT(1A) receptor function in major depressive disorder
    • PubMed doi:10.1016/j.pneurobio.2009.01.009
    • Savitz J, Lucki I, Drevets WC. 5-HT(1A) receptor function in major depressive disorder. Prog Neurobiol. 2009;88(1):17-31. PubMed doi:10.1016/j.pneurobio.2009.01.009.
    • (2009) Prog Neurobiol , vol.88 , Issue.1 , pp. 17-31
    • Savitz, J.1    Lucki, I.2    Drevets, W.C.3
  • 32
    • 34848912806 scopus 로고    scopus 로고
    • Serotonin-1A receptor imaging in recurrent depression: Replication and literature review
    • PubMed doi:10.1016/j.nucmedbio.2007.06.008
    • Drevets WC, Thase ME, Moses-Kolko EL, et al. Serotonin-1A receptor imaging in recurrent depression: replication and literature review. Nucl Med Biol. 2007;34(7):865-877. PubMed doi:10.1016/j.nucmedbio.2007.06.008.
    • (2007) Nucl Med Biol , vol.34 , Issue.7 , pp. 865-877
    • Drevets, W.C.1    Thase, M.E.2    Moses-Kolko, E.L.3
  • 33
    • 0033621542 scopus 로고    scopus 로고
    • Brain serotonin 1A receptor binding measured by positron emission tomography with [11C]WAY-100635: Effects of depression and antidepressant treatment
    • PubMed doi:10.1001/archpsyc.57.2.174
    • Sargent PA, Kjaer KH, Bench CJ, et al. Brain serotonin 1A receptor binding measured by positron emission tomography with [11C]WAY-100635: effects of depression and antidepressant treatment. Arch Gen Psychiatry. 2000;57(2):174-180. PubMed doi:10.1001/archpsyc.57.2.174.
    • (2000) Arch Gen Psychiatry , vol.57 , Issue.2 , pp. 174-180
    • Sargent, P.A.1    Kjaer, K.H.2    Bench, C.J.3
  • 34
    • 0028102141 scopus 로고
    • 5-HT1A receptors and pharmacotherapy: Is serotonin receptor down-regulation linked to the mechanism of action of antidepressant drugs?
    • PubMed
    • Stahl S. 5-HT1A receptors and pharmacotherapy: is serotonin receptor down-regulation linked to the mechanism of action of antidepressant drugs? Psychopharmacol Bull. 1994;30(1):39-43. PubMed.
    • (1994) Psychopharmacol Bull , vol.30 , Issue.1 , pp. 39-43
    • Stahl, S.1
  • 35
    • 0037304917 scopus 로고    scopus 로고
    • Is there a role for 5-HT1A agonists in the treatment of depression?
    • PubMed doi:10.1016/S0006-3223(02)01643-8
    • Blier P, Ward NM. Is there a role for 5-HT1A agonists in the treatment of depression? Biol Psychiatry. 2003;53(3):193-203. PubMed doi:10.1016/S0006-3223(02)01643-8.
    • (2003) Biol Psychiatry , vol.53 , Issue.3 , pp. 193-203
    • Blier, P.1    Ward, N.M.2
  • 36
    • 0031685344 scopus 로고    scopus 로고
    • Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive-compulsive disorder responses
    • PubMed doi:10.1016/S0006-3223(98)00114-0
    • Blier P, de Montigny C. Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive-compulsive disorder responses. Biol Psychiatry. 1998;44(5):313-323. PubMed doi:10.1016/S0006-3223(98)00114-0.
    • (1998) Biol Psychiatry , vol.44 , Issue.5 , pp. 313-323
    • Blier, P.1    de Montigny, C.2
  • 37
    • 4444260616 scopus 로고    scopus 로고
    • The therapeutic role of 5-HT1A and 5-HT2A receptors in depression
    • PubMed
    • Celada P, Puig M, Amargós-Bosch M, et al. The therapeutic role of 5-HT1A and 5-HT2A receptors in depression. J Psychiatry Neurosci. 2004;29(4):252-265. PubMed.
    • (2004) J Psychiatry Neurosci , vol.29 , Issue.4 , pp. 252-265
    • Celada, P.1    Puig, M.2    Amargós-Bosch, M.3
  • 38
    • 0034959682 scopus 로고    scopus 로고
    • Pharmacology of rapid-onset antidepressant treatment strategies
    • PubMed
    • Blier P. Pharmacology of rapid-onset antidepressant treatment strategies. J Clin Psychiatry. 2001;62(suppl 15):12-17. PubMed.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 15 , pp. 12-17
    • Blier, P.1
  • 39
    • 33644854626 scopus 로고    scopus 로고
    • Pindolol augmentation of antidepressant response
    • PubMed doi:10.2174/138945006775515446
    • Artigas F, Adell A, Celada P. Pindolol augmentation of antidepressant response. Curr Drug Targets. 2006;7(2):139-147. PubMed doi:10.2174/138945006775515446.
    • (2006) Curr Drug Targets , vol.7 , Issue.2 , pp. 139-147
    • Artigas, F.1    Adell, A.2    Celada, P.3
  • 40
    • 84862082116 scopus 로고    scopus 로고
    • A short-term double-blind randomized controlled pilot trial with active or placebo pindolol in patients treated with venlafaxine for major depression
    • PubMed doi:10.3109/08039488.2012.674553
    • Martiny K, Lunde M, Bech P, et al. A short-term double-blind randomized controlled pilot trial with active or placebo pindolol in patients treated with venlafaxine for major depression. Nord J Psychiatry. 2012;66(3):147-154. PubMed doi:10.3109/08039488.2012.674553.
    • (2012) Nord J Psychiatry , vol.66 , Issue.3 , pp. 147-154
    • Martiny, K.1    Lunde, M.2    Bech, P.3
  • 41
    • 79955487404 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, 8-week study of vilazodone, a serotonergic agent for the treatment of major depressive disorder
    • PubMed doi:10.4088/JCP.10m06596
    • Khan A, Cutler AJ, Kajdasz DK, et al. A randomized, double-blind, placebo-controlled, 8-week study of vilazodone, a serotonergic agent for the treatment of major depressive disorder. J Clin Psychiatry. 2011;72(4):441-447. PubMed doi:10.4088/JCP.10m06596.
    • (2011) J Clin Psychiatry , vol.72 , Issue.4 , pp. 441-447
    • Khan, A.1    Cutler, A.J.2    Kajdasz, D.K.3
  • 42
    • 33645099460 scopus 로고    scopus 로고
    • STAR*D Study Team. Medication augmentation after the failure of SSRIs for depression
    • PubMed doi:10.1056/NEJMoa052964
    • Trivedi MH, Fava M, Wisniewski SR, et al; STAR*D Study Team. Medication augmentation after the failure of SSRIs for depression. N Engl J Med. 2006;354(12):1243-1252. PubMed doi:10.1056/NEJMoa052964.
    • (2006) N Engl J Med , vol.354 , Issue.12 , pp. 1243-1252
    • Trivedi, M.H.1    Fava, M.2    Wisniewski, S.R.3
  • 44
    • 0031113488 scopus 로고    scopus 로고
    • Buspirone is an effective augmenting agent of serotonin selective reuptake inhibitors in severe treatment-refractory depression
    • PubMed
    • Bouwer C, Stein DJ. Buspirone is an effective augmenting agent of serotonin selective reuptake inhibitors in severe treatment-refractory depression. S Afr Med J. 1997;87(suppl):534-537, 540. PubMed.
    • (1997) S Afr Med J , vol.87 , Issue.SUPPL.
    • Bouwer, C.1    Stein, D.J.2
  • 45
    • 0025794099 scopus 로고
    • Possible augmentation of antidepressant response by buspirone
    • PubMed
    • Jacobsen FM. Possible augmentation of antidepressant response by buspirone. J Clin Psychiatry. 1991;52(5):217-220. PubMed.
    • (1991) J Clin Psychiatry , vol.52 , Issue.5 , pp. 217-220
    • Jacobsen, F.M.1
  • 46
    • 0027293819 scopus 로고
    • An open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression
    • PubMed
    • Joffe RT, Schuller DR. An open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression. J Clin Psychiatry. 1993;54(7):269-271. PubMed.
    • (1993) J Clin Psychiatry , vol.54 , Issue.7 , pp. 269-271
    • Joffe, R.T.1    Schuller, D.R.2
  • 47
    • 0034899926 scopus 로고    scopus 로고
    • Patients with severe depression may benefit from buspirone augmentation of selective serotonin reuptake inhibitors: Results from a placebo-controlled, randomized, double-blind, placebo wash-in study
    • PubMed doi:10.4088/JCP.v62n0608
    • Appelberg BG, Syvälahti EK, Koskinen TE, et al. Patients with severe depression may benefit from buspirone augmentation of selective serotonin reuptake inhibitors: results from a placebo-controlled, randomized, double-blind, placebo wash-in study. J Clin Psychiatry. 2001;62(6):448-452. PubMed doi:10.4088/JCP.v62n0608.
    • (2001) J Clin Psychiatry , vol.62 , Issue.6 , pp. 448-452
    • Appelberg, B.G.1    Syvälahti, E.K.2    Koskinen, T.E.3
  • 48
    • 0041508892 scopus 로고    scopus 로고
    • Faster response in depressive patients treated with fluoxetine alone than in combination with buspirone
    • PubMed doi:10.1016/S0165-0327(02)00090-3
    • Onder E, Tural U. Faster response in depressive patients treated with fluoxetine alone than in combination with buspirone. J Affect Disord. 2003;76(1-3):223-227. PubMed doi:10.1016/S0165-0327(02)00090-3.
    • (2003) J Affect Disord , vol.76 , Issue.1-3 , pp. 223-227
    • Onder, E.1    Tural, U.2
  • 49
    • 10744220820 scopus 로고    scopus 로고
    • STAR*D Investigators Group. Sequenced Treatment Alternatives to Relieve Depression (STAR*D): Rationale and design
    • PubMed doi:10.1016/S0197-2456(03)00112-0
    • Rush AJ, Fava M, Wisniewski SR, et al; STAR*D Investigators Group. Sequenced Treatment Alternatives to Relieve Depression (STAR*D): rationale and design. Control Clin Trials. 2004;25(1):119-142. PubMed doi:10.1016/S0197-2456(03)00112-0.
    • (2004) Control Clin Trials , vol.25 , Issue.1 , pp. 119-142
    • Rush, A.J.1    Fava, M.2    Wisniewski, S.R.3
  • 50
    • 79960706921 scopus 로고    scopus 로고
    • Can we really accelerate and enhance the selective serotonin reuptake inhibitor antidepressant effect? a randomized clinical trial and a meta-analysis of pindolol in nonresistant depression
    • PubMed doi:10.4088/JCP.09m05827blu
    • Portella MJ, de Diego-Adeliño J, Ballesteros J, et al. Can we really accelerate and enhance the selective serotonin reuptake inhibitor antidepressant effect? a randomized clinical trial and a meta-analysis of pindolol in nonresistant depression. J Clin Psychiatry. 2011;72(7):962-969. PubMed doi:10.4088/JCP.09m05827blu.
    • (2011) J Clin Psychiatry , vol.72 , Issue.7 , pp. 962-969
    • Portella, M.J.1    de Diego-Adeliño, J.2    Ballesteros, J.3
  • 51
    • 0031396455 scopus 로고    scopus 로고
    • How long should pindolol be associated with paroxetine to improve the antidepressant response?
    • PubMed doi:10.1097/00004714-199712000-00002
    • Zanardi R, Artigas F, Franchini L, et al. How long should pindolol be associated with paroxetine to improve the antidepressant response? J Clin Psychopharmacol. 1997;17(6):446-450. PubMed doi:10.1097/00004714-199712000-00002.
    • (1997) J Clin Psychopharmacol , vol.17 , Issue.6 , pp. 446-450
    • Zanardi, R.1    Artigas, F.2    Franchini, L.3
  • 52
    • 0031710996 scopus 로고    scopus 로고
    • Effect of pindolol on onset of action of paroxetine in the treatment of major depression: Intermediate analysis of a double-blind, placebo-controlled trial: Réseau de Recherche et d'Expérimentation Psychopharmacologique
    • PubMed
    • Bordet R, Thomas P, Dupuis B. Effect of pindolol on onset of action of paroxetine in the treatment of major depression: intermediate analysis of a double-blind, placebo-controlled trial: Réseau de Recherche et d'Expérimentation Psychopharmacologique. Am J Psychiatry. 1998;155(10):1346-1351. PubMed.
    • (1998) Am J Psychiatry , vol.155 , Issue.10 , pp. 1346-1351
    • Bordet, R.1    Thomas, P.2    Dupuis, B.3
  • 53
    • 0032905345 scopus 로고    scopus 로고
    • Pindolol and mianserin augment the antidepressant activity of fluoxetine in hospitalized major depressed patients, including those with treatment resistance
    • PubMed doi:10.1097/00004714-199904000-00014
    • Maes M, Libbrecht I, van Hunsel F, et al. Pindolol and mianserin augment the antidepressant activity of fluoxetine in hospitalized major depressed patients, including those with treatment resistance. J Clin Psychopharmacol. 1999;19(2):177-182. PubMed doi:10.1097/00004714-199904000-00014.
    • (1999) J Clin Psychopharmacol , vol.19 , Issue.2 , pp. 177-182
    • Maes, M.1    Libbrecht, I.2    van Hunsel, F.3
  • 54
    • 37349087861 scopus 로고    scopus 로고
    • Paroxetine with pindolol augmentation: A double-blind, randomized, placebo-controlled study in depressed in-patients
    • PubMed doi:10.1016/j.euroneuro.2007.09.002
    • Geretsegger C, Bitterlich W, Stelzig R, et al. Paroxetine with pindolol augmentation: a double-blind, randomized, placebo-controlled study in depressed in-patients. Eur Neuropsychopharmacol. 2008;18(2):141-146. PubMed doi:10.1016/j.euroneuro.2007.09.002.
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.2 , pp. 141-146
    • Geretsegger, C.1    Bitterlich, W.2    Stelzig, R.3
  • 55
    • 0342894667 scopus 로고    scopus 로고
    • Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment
    • PubMed doi:10.1016/S0140-6736(96)08007-5
    • Pérez V, Gilaberte I, Faries D, et al. Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment. Lancet. 1997;349(9065):1594-1597. PubMed doi:10.1016/S0140-6736(96)08007-5.
    • (1997) Lancet , vol.349 , Issue.9065 , pp. 1594-1597
    • Pérez, V.1    Gilaberte, I.2    Faries, D.3
  • 56
    • 67349194332 scopus 로고    scopus 로고
    • Pindolol augmentation enhances response outcomes in first depressive episodes
    • PubMed doi:10.1016/j.euroneuro.2009.04.004
    • Portella MJ, de Diego-Adeliño J, Puigdemont D, et al. Pindolol augmentation enhances response outcomes in first depressive episodes. Eur Neuropsychopharmacol. 2009;19(7):516-519. PubMed doi:10.1016/j.euroneuro.2009.04.004.
    • (2009) Eur Neuropsychopharmacol , vol.19 , Issue.7 , pp. 516-519
    • Portella, M.J.1    de Diego-Adeliño, J.2    Puigdemont, D.3
  • 57
    • 0033135316 scopus 로고    scopus 로고
    • The use of pindolol with fluoxetine in the treatment of major depression: Final results from a double-blind, placebo-controlled trial
    • PubMed doi:10.1016/S0006-3223(98)00383-7
    • Berman RM, Anand A, Cappiello A, et al. The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial. Biol Psychiatry. 1999;45(9):1170-1177. PubMed doi:10.1016/S0006-3223(98)00383-7.
    • (1999) Biol Psychiatry , vol.45 , Issue.9 , pp. 1170-1177
    • Berman, R.M.1    Anand, A.2    Cappiello, A.3
  • 58
    • 0031022587 scopus 로고    scopus 로고
    • Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: A double-blind, placebo-controlled trial
    • PubMed
    • Berman RM, Darnell AM, Miller HL, et al. Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial. Am J Psychiatry. 1997;154(1):37-43. PubMed.
    • (1997) Am J Psychiatry , vol.154 , Issue.1 , pp. 37-43
    • Berman, R.M.1    Darnell, A.M.2    Miller, H.L.3
  • 59
    • 0344889217 scopus 로고    scopus 로고
    • A double-blind, randomized, placebo-controlled trial of pindolol augmentation in depressive patients resistant to serotonin reuptake inhibitors: Grup de Recerca en Trastorns Afectius
    • PubMed doi:10.1001/archpsyc.56.4.375
    • Pérez V, Soler J, Puigdemont D, et al. A double-blind, randomized, placebo-controlled trial of pindolol augmentation in depressive patients resistant to serotonin reuptake inhibitors: Grup de Recerca en Trastorns Afectius. Arch Gen Psychiatry. 1999;56(4):375-379. PubMed doi:10.1001/archpsyc.56.4.375.
    • (1999) Arch Gen Psychiatry , vol.56 , Issue.4 , pp. 375-379
    • Pérez, V.1    Soler, J.2    Puigdemont, D.3
  • 60
    • 1842844954 scopus 로고    scopus 로고
    • Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: A double-blind, randomized, controlled trial
    • PubMed doi:10.4088/JCP.v65n0215
    • Perry EB, Berman RM, Sanacora G, et al. Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial. J Clin Psychiatry. 2004;65(2):238-243. PubMed doi:10.4088/JCP.v65n0215.
    • (2004) J Clin Psychiatry , vol.65 , Issue.2 , pp. 238-243
    • Perry, E.B.1    Berman, R.M.2    Sanacora, G.3
  • 61
    • 17644399822 scopus 로고    scopus 로고
    • Pindolol augmentation of selective serotonin reuptake inhibitors: Accounting for the variability of results of placebo-controlled double-blind studies in patients with major depression
    • PubMed doi:10.1002/hup.672
    • Segrave R, Nathan PJ. Pindolol augmentation of selective serotonin reuptake inhibitors: accounting for the variability of results of placebo-controlled double-blind studies in patients with major depression. Hum Psychopharmacol. 2005;20(3):163-174. PubMed doi:10.1002/hup.672.
    • (2005) Hum Psychopharmacol , vol.20 , Issue.3 , pp. 163-174
    • Segrave, R.1    Nathan, P.J.2
  • 62
    • 1542404781 scopus 로고    scopus 로고
    • Effectiveness of pindolol plus serotonin uptake inhibitors in depression: A meta-analysis of early and late outcomes from randomised controlled trials
    • PubMed doi:10.1016/S0165-0327(02)00404-4
    • Ballesteros J, Callado LF. Effectiveness of pindolol plus serotonin uptake inhibitors in depression: a meta-analysis of early and late outcomes from randomised controlled trials. J Affect Disord. 2004;79(1-3):137-147. PubMed doi:10.1016/S0165-0327(02)00404-4.
    • (2004) J Affect Disord , vol.79 , Issue.1-3 , pp. 137-147
    • Ballesteros, J.1    Callado, L.F.2
  • 63
    • 77950419702 scopus 로고    scopus 로고
    • Pindolol augmentation of serotonin reuptake inhibitors for the treatment of depressive disorder: A systematic review
    • PubMed doi:10.1177/0269881108097714
    • Whale R, Terao T, Cowen P, et al. Pindolol augmentation of serotonin reuptake inhibitors for the treatment of depressive disorder: a systematic review. J Psychopharmacol. 2010;24(4):513-520. PubMed doi:10.1177/0269881108097714.
    • (2010) J Psychopharmacol , vol.24 , Issue.4 , pp. 513-520
    • Whale, R.1    Terao, T.2    Cowen, P.3
  • 64
    • 84897952581 scopus 로고    scopus 로고
    • St Louis
    • Viibryd [package insert]
    • Viibryd [package insert]. St Louis, MO: Forest Pharmaceuticals Inc; 2012.
    • (2012) MO: Forest Pharmaceuticals Inc
  • 65
    • 84885480792 scopus 로고    scopus 로고
    • Electrophysiological evidence for rapid 5-HT1A autoreceptor inhibition by vilazodone, a 5-HT1A receptor partial agonist and 5-HT reuptake inhibitor
    • PubMed doi:10.1016/j.ejphar.2013.07.014
    • Ashby CR Jr, Kehne JH, Bartoszyk GD, et al. Electrophysiological evidence for rapid 5-HT1A autoreceptor inhibition by vilazodone, a 5-HT1A receptor partial agonist and 5-HT reuptake inhibitor. Eur J Pharmacol. 2013;714(1-3):359-365. PubMed doi:10.1016/j.ejphar.2013.07.014.
    • (2013) Eur J Pharmacol , vol.714 , Issue.1-3 , pp. 359-365
    • Ashby Jr., C.R.1    Kehne, J.H.2    Bartoszyk, G.D.3
  • 66
    • 0036720479 scopus 로고    scopus 로고
    • Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): A combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist
    • PubMed doi:10.1124/jpet.102.034280
    • Page ME, Cryan JF, Sullivan A, et al. Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist. J Pharmacol Exp Ther. 2002;302(3):1220-1227. PubMed doi:10.1124/jpet.102.034280.
    • (2002) J Pharmacol Exp Ther , vol.302 , Issue.3 , pp. 1220-1227
    • Page, M.E.1    Cryan, J.F.2    Sullivan, A.3
  • 67
    • 14644439152 scopus 로고    scopus 로고
    • Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone
    • PubMed doi:10.1016/j.ejphar.2005.01.018
    • Hughes ZA, Starr KR, Langmead CJ, et al. Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone. Eur J Pharmacol. 2005;510(1-2):49-57. PubMed doi:10.1016/j.ejphar.2005.01.018.
    • (2005) Eur J Pharmacol , vol.510 , Issue.1-2 , pp. 49-57
    • Hughes, Z.A.1    Starr, K.R.2    Langmead, C.J.3
  • 68
    • 64149093513 scopus 로고    scopus 로고
    • Evidence for efficacy and tolerability of vilazodone in the treatment of major depressive disorder: A randomized, double-blind, placebo-controlled trial
    • PubMed doi:10.4088/JCP.08m04637
    • Rickels K, Athanasiou M, Robinson DS, et al. Evidence for efficacy and tolerability of vilazodone in the treatment of major depressive disorder: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2009;70(3):326-333. PubMed doi:10.4088/JCP.08m04637.
    • (2009) J Clin Psychiatry , vol.70 , Issue.3 , pp. 326-333
    • Rickels, K.1    Athanasiou, M.2    Robinson, D.S.3
  • 69
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 70
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • PubMed doi:10.1192/bjp.134.4.382
    • Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979;134(4):382-389. PubMed doi:10.1192/bjp.134.4.382.
    • (1979) Br J Psychiatry , vol.134 , Issue.4 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 71
    • 72949151592 scopus 로고
    • A rating scale for depression
    • PubMed doi:10.1136/jnnp.23.1.56
    • Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry. 1960;23(1):56-62. PubMed doi:10.1136/jnnp.23.1.56.
    • (1960) J Neurol Neurosurg Psychiatry , vol.23 , Issue.1 , pp. 56-62
    • Hamilton, M.1
  • 72
    • 84893272144 scopus 로고    scopus 로고
    • Early and sustained improvement with vilazodone in adult patients with major depressive disorder: post hoc analyses of two phase III trials [published online ahead of print October 31, 2013], PubMed doi:10.1185/03007995.2013.855188
    • Jain R, Chen D, Edwards J, et al. Early and sustained improvement with vilazodone in adult patients with major depressive disorder: post hoc analyses of two phase III trials [published online ahead of print October 31, 2013]. Curr Med Res Opin. PubMed doi:10.1185/03007995.2013.855188.
    • Curr Med Res Opin
    • Jain, R.1    Chen, D.2    Edwards, J.3
  • 73
    • 84859110061 scopus 로고    scopus 로고
    • Vilazodone for major depressive disorder: A systematic review of the efficacy and safety profile for this newly approved antidepressant: What is the number needed to treat, number needed to harm and likelihood to be helped or harmed?
    • PubMed doi:10.1111/j.1742-1241.2011.02885.x
    • Citrome L. Vilazodone for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antidepressant: what is the number needed to treat, number needed to harm and likelihood to be helped or harmed? Int J Clin Pract. 2012;66(4):356-368. PubMed doi:10.1111/j.1742-1241.2011.02885.x.
    • (2012) Int J Clin Pract , vol.66 , Issue.4 , pp. 356-368
    • Citrome, L.1
  • 74
    • 0036232572 scopus 로고    scopus 로고
    • Prevalence of sexual dysfunction among newer antidepressants
    • PubMed doi:10.4088/JCP.v63n0414
    • Clayton AH, Pradko JF, Croft HA, et al. Prevalence of sexual dysfunction among newer antidepressants. J Clin Psychiatry. 2002;63(4):357-366. PubMed doi:10.4088/JCP.v63n0414.
    • (2002) J Clin Psychiatry , vol.63 , Issue.4 , pp. 357-366
    • Clayton, A.H.1    Pradko, J.F.2    Croft, H.A.3
  • 75
    • 34447508258 scopus 로고    scopus 로고
    • Changes in sexual functioning associated with duloxetine, escitalopram, and placebo in the treatment of patients with major depressive disorder
    • PubMed doi:10.1111/j.1743-6109.2007.00520.x
    • Clayton A, Kornstein S, Prakash A, et al. Changes in sexual functioning associated with duloxetine, escitalopram, and placebo in the treatment of patients with major depressive disorder. J Sex Med. 2007;4(4, pt 1):917-929. PubMed doi:10.1111/j.1743-6109.2007.00520.x.
    • (2007) J Sex Med , vol.4 , Issue.4 PART 1 , pp. 917-929
    • Clayton, A.1    Kornstein, S.2    Prakash, A.3
  • 76
    • 84885928296 scopus 로고    scopus 로고
    • The effect of vilazodone on sexual function during the treatment of major depressive disorder
    • PubMed doi: 10.1111/jsm.12004
    • Clayton AH, Kennedy SH, Edwards JB, et al. The effect of vilazodone on sexual function during the treatment of major depressive disorder. J Sex Med. 2013 Oct;10(10):2465-2476. PubMed doi: 10.1111/jsm.12004.
    • (2013) J Sex Med , vol.10 , Issue.10 , pp. 2465-2476
    • Clayton, A.H.1    Kennedy, S.H.2    Edwards, J.B.3
  • 77
    • 0028566898 scopus 로고
    • Buspirone treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors
    • doi:10.1002/depr.3050020208
    • Norden M. Buspirone treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors. Depression. 1994;2(2):109-112. doi:10.1002/depr.3050020208
    • (1994) Depression , vol.2 , Issue.2 , pp. 109-112
    • Norden, M.1
  • 78
    • 0032925471 scopus 로고    scopus 로고
    • Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors
    • PubMed doi:10.1097/00004714-199906000-00012
    • Landén M, Eriksson E, Agren H, et al. Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors. J Clin Psychopharmacol. 1999;19(3):268-271. PubMed doi:10.1097/00004714-199906000-00012.
    • (1999) J Clin Psychopharmacol , vol.19 , Issue.3 , pp. 268-271
    • Landén, M.1    Eriksson, E.2    Agren, H.3
  • 79
    • 0033964945 scopus 로고    scopus 로고
    • Female sexual dysfunction associated with antidepressant administration: A randomized, placebo-controlled study of pharmacologic intervention
    • PubMed doi:10.1176/appi.ajp.157.2.239
    • Michelson D, Bancroft J, Targum S, et al. Female sexual dysfunction associated with antidepressant administration: a randomized, placebo-controlled study of pharmacologic intervention. Am J Psychiatry. 2000;157(2):239-243. PubMed doi:10.1176/appi.ajp.157.2.239.
    • (2000) Am J Psychiatry , vol.157 , Issue.2 , pp. 239-243
    • Michelson, D.1    Bancroft, J.2    Targum, S.3
  • 80
    • 0023222901 scopus 로고
    • Effect of buspirone on sexual dysfunction in patients with generalized anxiety disorder
    • PubMed
    • Othmer E, Othmer SC. Effect of buspirone on sexual dysfunction in patients with generalized anxiety disorder. J Clin Psychiatry. 1987;48(5):201-203. PubMed.
    • (1987) J Clin Psychiatry , vol.48 , Issue.5 , pp. 201-203
    • Othmer, E.1    Othmer, S.C.2
  • 81
    • 80052999964 scopus 로고    scopus 로고
    • Vilazodone: Clinical basis for the US Food and Drug Administration's approval of a new antidepressant
    • PubMed doi:10.4088/JCP.11r06984
    • Laughren TP, Gobburu J, Temple RJ, et al. Vilazodone: clinical basis for the US Food and Drug Administration's approval of a new antidepressant. J Clin Psychiatry. 2011;72(9):1166-1173. PubMed doi:10.4088/JCP.11r06984.
    • (2011) J Clin Psychiatry , vol.72 , Issue.9 , pp. 1166-1173
    • Laughren, T.P.1    Gobburu, J.2    Temple, R.J.3
  • 82
    • 42449118921 scopus 로고    scopus 로고
    • Difference in treatment outcome in outpatients with anxious versus nonanxious depression: A STAR*D report
    • PubMed doi:10.1176/appi.ajp.2007.06111868
    • Fava M, Rush AJ, Alpert JE, et al. Difference in treatment outcome in outpatients with anxious versus nonanxious depression: a STAR*D report. Am J Psychiatry. 2008;165(3):342-351. PubMed doi:10.1176/appi.ajp.2007.06111868.
    • (2008) Am J Psychiatry , vol.165 , Issue.3 , pp. 342-351
    • Fava, M.1    Rush, A.J.2    Alpert, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.