-
1
-
-
80051580618
-
Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
10.3322/caac.20121, 21685461
-
Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011, 61:212-236. 10.3322/caac.20121, 21685461.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
Jemal, A.4
-
2
-
-
33745276511
-
Increased expression of pAKT is associated with radiation resistance in cervical cancer
-
2361323, 16721365
-
Kim TJ, Lee JW, Song SY, Choi JJ, Choi CH, Kim BG, Lee JH, Bae DS. Increased expression of pAKT is associated with radiation resistance in cervical cancer. Br J Cancer 2006, 94:1678-1682. 2361323, 16721365.
-
(2006)
Br J Cancer
, vol.94
, pp. 1678-1682
-
-
Kim, T.J.1
Lee, J.W.2
Song, S.Y.3
Choi, J.J.4
Choi, C.H.5
Kim, B.G.6
Lee, J.H.7
Bae, D.S.8
-
3
-
-
77949661216
-
Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation
-
10.1371/journal.pone.0009582, 2833198, 20221395
-
Wang J, Huang L, Li J, Fan Q, Long Y, Li Y, Zhou B. Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation. PLoS One 2010, 5:e9582. 10.1371/journal.pone.0009582, 2833198, 20221395.
-
(2010)
PLoS One
, vol.5
-
-
Wang, J.1
Huang, L.2
Li, J.3
Fan, Q.4
Long, Y.5
Li, Y.6
Zhou, B.7
-
4
-
-
40849097597
-
Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation
-
10.1016/j.ijpharm.2007.09.003, 17942255
-
Ase I, Lai H, Singh NP, Sasaki T. Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation. Int J Pharm 2008, 354:28-33. 10.1016/j.ijpharm.2007.09.003, 17942255.
-
(2008)
Int J Pharm
, vol.354
, pp. 28-33
-
-
Ase, I.1
Lai, H.2
Singh, N.P.3
Sasaki, T.4
-
5
-
-
51549118662
-
The antiviral activities of artemisinin and artesunate
-
Efferth T, Romero MR, Wolf DG, Stamminger T, Marin JJ, Marschall M. The antiviral activities of artemisinin and artesunate. Clin Infect Dis 2008, 47:804-811.
-
(2008)
Clin Infect Dis
, vol.47
, pp. 804-811
-
-
Efferth, T.1
Romero, M.R.2
Wolf, D.G.3
Stamminger, T.4
Marin, J.J.5
Marschall, M.6
-
6
-
-
84865427860
-
Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells
-
10.1002/jcp.24086, 22378505
-
Zhou C, Pan W, Wang XP, Chen TS. Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells. J Cell Physiol 2012, 227:3778-3786. 10.1002/jcp.24086, 22378505.
-
(2012)
J Cell Physiol
, vol.227
, pp. 3778-3786
-
-
Zhou, C.1
Pan, W.2
Wang, X.P.3
Chen, T.S.4
-
7
-
-
83355166871
-
Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells
-
10.1158/1535-7163.MCT-11-0534, 21998290
-
Berdelle N, Nikolova T, Quiros S, Efferth T, Kaina B. Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells. Mol Cancer Ther 2011, 10:2224-2233. 10.1158/1535-7163.MCT-11-0534, 21998290.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 2224-2233
-
-
Berdelle, N.1
Nikolova, T.2
Quiros, S.3
Efferth, T.4
Kaina, B.5
-
8
-
-
84862780354
-
Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells
-
10.1097/CAD.0b013e328350e8ac, 22421370
-
Jiang Z, Chai J, Chuang HH, Li S, Wang T, Cheng Y, Chen W, Zhou D. Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells. Anticancer Drugs 2012, 23:606-613. 10.1097/CAD.0b013e328350e8ac, 22421370.
-
(2012)
Anticancer Drugs
, vol.23
, pp. 606-613
-
-
Jiang, Z.1
Chai, J.2
Chuang, H.H.3
Li, S.4
Wang, T.5
Cheng, Y.6
Chen, W.7
Zhou, D.8
-
9
-
-
84863698278
-
Selective radiosensitization of human cervical cancer cells and normal cells by artemisinin through the abrogation of radiation-induced G2 block
-
10.1097/IGC.0b013e31824a67c9, 22552829
-
Gong XM, Zhang Q, Torossian A, Cao JP, Fu S. Selective radiosensitization of human cervical cancer cells and normal cells by artemisinin through the abrogation of radiation-induced G2 block. Int J Gynecol Cancer 2012, 22:718-724. 10.1097/IGC.0b013e31824a67c9, 22552829.
-
(2012)
Int J Gynecol Cancer
, vol.22
, pp. 718-724
-
-
Gong, X.M.1
Zhang, Q.2
Torossian, A.3
Cao, J.P.4
Fu, S.5
-
10
-
-
84875019567
-
Dihydroartemisinin induces radiosensitivity in cervical cancer cells by modulating cell cycle progression
-
Luo J, Chen X, Chen G, Zhou X, Lu X, Ling Y, Zhang S, Zhu W, Cao J. Dihydroartemisinin induces radiosensitivity in cervical cancer cells by modulating cell cycle progression. Saudi Med J 2009, 34:254-260.
-
(2009)
Saudi Med J
, vol.34
, pp. 254-260
-
-
Luo, J.1
Chen, X.2
Chen, G.3
Zhou, X.4
Lu, X.5
Ling, Y.6
Zhang, S.7
Zhu, W.8
Cao, J.9
-
11
-
-
84861797048
-
A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin
-
10.1016/j.radonc.2012.03.018, 22560712
-
Reichert S, Reinboldt V, Hehlgans S, Efferth T, Rodel C, Rodel F. A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin. Radiother Oncol 2012, 103:394-401. 10.1016/j.radonc.2012.03.018, 22560712.
-
(2012)
Radiother Oncol
, vol.103
, pp. 394-401
-
-
Reichert, S.1
Reinboldt, V.2
Hehlgans, S.3
Efferth, T.4
Rodel, C.5
Rodel, F.6
-
12
-
-
81855168327
-
Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase
-
10.1016/j.intimp.2011.08.017, 21907831
-
Zhao Y, Jiang W, Li B, Yao Q, Dong J, Cen Y, Pan X, Li J, Zheng J, Pang X. Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase. Int Immunopharmacol 2011, 11:2039-2046. 10.1016/j.intimp.2011.08.017, 21907831.
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 2039-2046
-
-
Zhao, Y.1
Jiang, W.2
Li, B.3
Yao, Q.4
Dong, J.5
Cen, Y.6
Pan, X.7
Li, J.8
Zheng, J.9
Pang, X.10
-
13
-
-
79956345262
-
VEGF-C promotes the development of esophageal cancer via regulating CNTN-1 expression
-
10.1016/j.cyto.2011.03.008, 21482472
-
Liu P, Zhou J, Zhu H, Xie L, Wang F, Liu B, Shen W, Ye W, Xiang B, Zhu X. VEGF-C promotes the development of esophageal cancer via regulating CNTN-1 expression. Cytokine 2011, 55:8-17. 10.1016/j.cyto.2011.03.008, 21482472.
-
(2011)
Cytokine
, vol.55
, pp. 8-17
-
-
Liu, P.1
Zhou, J.2
Zhu, H.3
Xie, L.4
Wang, F.5
Liu, B.6
Shen, W.7
Ye, W.8
Xiang, B.9
Zhu, X.10
-
14
-
-
72949123931
-
Control of the G2/M checkpoints after exposure to low doses of ionising radiation: implications for hyper-radiosensitivity
-
10.1016/j.dnarep.2009.10.006, 19926348
-
Fernet M, Megnin-Chanet F, Hall J, Favaudon V. Control of the G2/M checkpoints after exposure to low doses of ionising radiation: implications for hyper-radiosensitivity. DNA Repair (Amst) 2010, 9:48-57. 10.1016/j.dnarep.2009.10.006, 19926348.
-
(2010)
DNA Repair (Amst)
, vol.9
, pp. 48-57
-
-
Fernet, M.1
Megnin-Chanet, F.2
Hall, J.3
Favaudon, V.4
-
15
-
-
33344476097
-
DNA damage checkpoints in mammals
-
Niida H, Nakanishi M. DNA damage checkpoints in mammals. Mutagenesis 2006, 21:3-9.
-
(2006)
Mutagenesis
, vol.21
, pp. 3-9
-
-
Niida, H.1
Nakanishi, M.2
-
16
-
-
77956517283
-
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma
-
10.1016/j.ccr.2010.08.011, 3115571, 20832752
-
Mir SE, de Witt Hamer PC, Krawczyk PM, Balaj L, Claes A, Niers JM. In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell 2010, 18:244-257. 10.1016/j.ccr.2010.08.011, 3115571, 20832752.
-
(2010)
Cancer Cell
, vol.18
, pp. 244-257
-
-
Mir, S.E.1
de Witt Hamer, P.C.2
Krawczyk, P.M.3
Balaj, L.4
Claes, A.5
Niers, J.M.6
-
17
-
-
34249337705
-
Cdc25 and Wee1: analogous opposites?
-
10.1186/1747-1028-2-12, 1868713, 17480229
-
Perry JA, Kornbluth S. Cdc25 and Wee1: analogous opposites?. Cell Div 2007, 2:12. 10.1186/1747-1028-2-12, 1868713, 17480229.
-
(2007)
Cell Div
, vol.2
, pp. 12
-
-
Perry, J.A.1
Kornbluth, S.2
-
18
-
-
79551537504
-
Cell cycle control and DNA damage response of conditionally immortalized urothelial cells
-
10.1371/journal.pone.0016595, 3030598, 21305048
-
Dixon BP, Henry J, Siroky BJ, Chu A, Groen PA, Bissler JJ. Cell cycle control and DNA damage response of conditionally immortalized urothelial cells. PLoS One 2011, 6:e16595. 10.1371/journal.pone.0016595, 3030598, 21305048.
-
(2011)
PLoS One
, vol.6
-
-
Dixon, B.P.1
Henry, J.2
Siroky, B.J.3
Chu, A.4
Groen, P.A.5
Bissler, J.J.6
-
19
-
-
0033516474
-
Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite
-
10.1074/jbc.274.27.19383, 10383451
-
Pandey AV, Tekwani BL, Singh RL, Chauhan VS. Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite. J Biol Chem 1999, 274:19383-19388. 10.1074/jbc.274.27.19383, 10383451.
-
(1999)
J Biol Chem
, vol.274
, pp. 19383-19388
-
-
Pandey, A.V.1
Tekwani, B.L.2
Singh, R.L.3
Chauhan, V.S.4
-
20
-
-
33644980165
-
The reaction of artemisinins with hemoglobin: a unified picture
-
10.1016/j.bmc.2005.12.038, 16412643
-
Messori L, Gabbiani C, Casini A, Siragusa M, Vincieri FF, Bilia AR. The reaction of artemisinins with hemoglobin: a unified picture. Bioorg Med Chem 2006, 14:2972-2977. 10.1016/j.bmc.2005.12.038, 16412643.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 2972-2977
-
-
Messori, L.1
Gabbiani, C.2
Casini, A.3
Siragusa, M.4
Vincieri, F.F.5
Bilia, A.R.6
-
21
-
-
0035315838
-
The anti-malarial artesunate is also active against cancer
-
Efferth T, Dunstan H, Sauerbrey A, Miyachi H, Chitambar CR. The anti-malarial artesunate is also active against cancer. Int J Oncol 2001, 18:767-773.
-
(2001)
Int J Oncol
, vol.18
, pp. 767-773
-
-
Efferth, T.1
Dunstan, H.2
Sauerbrey, A.3
Miyachi, H.4
Chitambar, C.R.5
-
22
-
-
0042844638
-
Molecular modes of action of artesunate in tumor cell lines
-
10.1124/mol.64.2.382, 12869643
-
Efferth T, Sauerbrey A, Olbrich A, Gebhart E, Rauch P, Weber HO, Hengstler JG, Halatsch ME, Volm M, Tew KD. Molecular modes of action of artesunate in tumor cell lines. Mol Pharmacol 2003, 64:382-394. 10.1124/mol.64.2.382, 12869643.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 382-394
-
-
Efferth, T.1
Sauerbrey, A.2
Olbrich, A.3
Gebhart, E.4
Rauch, P.5
Weber, H.O.6
Hengstler, J.G.7
Halatsch, M.E.8
Volm, M.9
Tew, K.D.10
-
23
-
-
79953194472
-
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production
-
10.1074/jbc.M110.210047, 3057810, 21149439
-
Hamacher-Brady A, Stein HA, Turschner S, Toegel I, Mora R, Jennewein N, Efferth T, Eils R, Brady NR. Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production. J Biol Chem 2011, 286:6587-6601. 10.1074/jbc.M110.210047, 3057810, 21149439.
-
(2011)
J Biol Chem
, vol.286
, pp. 6587-6601
-
-
Hamacher-Brady, A.1
Stein, H.A.2
Turschner, S.3
Toegel, I.4
Mora, R.5
Jennewein, N.6
Efferth, T.7
Eils, R.8
Brady, N.R.9
-
24
-
-
1442269676
-
Role of p53 in G2/M cell cycle arrest and apoptosis in response to gamma-irradiation in ovarian carcinoma cell lines
-
Concin N, Stimpfl M, Zeillinger C, Wolff U, Hefler L, Sedlak J, Leodolter S, Zeillinger R. Role of p53 in G2/M cell cycle arrest and apoptosis in response to gamma-irradiation in ovarian carcinoma cell lines. Int J Oncol 2003, 22:51-57.
-
(2003)
Int J Oncol
, vol.22
, pp. 51-57
-
-
Concin, N.1
Stimpfl, M.2
Zeillinger, C.3
Wolff, U.4
Hefler, L.5
Sedlak, J.6
Leodolter, S.7
Zeillinger, R.8
-
25
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
10.1038/nrm2351, 18285803
-
Branzei D, Foiani M. Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 2008, 9:297-308. 10.1038/nrm2351, 18285803.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
26
-
-
4444344407
-
G2 checkpoint abrogators as anticancer drugs
-
Kawabe T. G2 checkpoint abrogators as anticancer drugs. Mol Cancer Ther 2004, 3:513-519.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 513-519
-
-
Kawabe, T.1
-
27
-
-
78649237831
-
Abrogation of the G2 checkpoint by inhibition of Wee-1 kinase results in sensitization of p53-deficient tumor cells to DNA-damaging agents
-
10.2174/157488410791498824, 20406171
-
Leijen S, Beijnen JH, Schellens JH. Abrogation of the G2 checkpoint by inhibition of Wee-1 kinase results in sensitization of p53-deficient tumor cells to DNA-damaging agents. Curr Clin Pharmacol 2010, 5:186-191. 10.2174/157488410791498824, 20406171.
-
(2010)
Curr Clin Pharmacol
, vol.5
, pp. 186-191
-
-
Leijen, S.1
Beijnen, J.H.2
Schellens, J.H.3
-
28
-
-
0028196623
-
In vitro studies of Taxol as a radiation sensitizer in human tumor cells
-
10.1093/jnci/86.6.441, 7907149
-
Liebmann J, Cook JA, Fisher J, Teague D, Mitchell JB. In vitro studies of Taxol as a radiation sensitizer in human tumor cells. J Natl Cancer Inst 1994, 86:441-446. 10.1093/jnci/86.6.441, 7907149.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 441-446
-
-
Liebmann, J.1
Cook, J.A.2
Fisher, J.3
Teague, D.4
Mitchell, J.B.5
-
29
-
-
79955402190
-
WEE1 inhibition sensitizes osteosarcoma to radiotherapy
-
10.1186/1471-2407-11-156, 3103478, 21529352
-
PosthumaDeBoer J, Wurdinger T, Graat HC, van Beusechem VW, Helder MN, van Royen BJ, Kaspers GJ. WEE1 inhibition sensitizes osteosarcoma to radiotherapy. BMC Cancer 2011, 11:156. 10.1186/1471-2407-11-156, 3103478, 21529352.
-
(2011)
BMC Cancer
, vol.11
, pp. 156
-
-
PosthumaDeBoer, J.1
Wurdinger, T.2
Graat, H.C.3
van Beusechem, V.W.4
Helder, M.N.5
van Royen, B.J.6
Kaspers, G.J.7
-
30
-
-
77949907684
-
Activation domain-dependent degradation of somatic Wee1 kinase
-
10.1074/jbc.M109.093237, 2825470, 20038582
-
Owens L, Simanski S, Squire C, Smith A, Cartzendafner J, Cavett V. Activation domain-dependent degradation of somatic Wee1 kinase. J Biol Chem 2010, 285:6761-6769. 10.1074/jbc.M109.093237, 2825470, 20038582.
-
(2010)
J Biol Chem
, vol.285
, pp. 6761-6769
-
-
Owens, L.1
Simanski, S.2
Squire, C.3
Smith, A.4
Cartzendafner, J.5
Cavett, V.6
-
31
-
-
67651160414
-
Temporal gradient in the clock gene and cell-cycle checkpoint kinase Wee1 expression along the gut
-
10.1080/07420520902924889, 19444744
-
Polidarova L, Sotak M, Sladek M, Pacha J, Sumova A. Temporal gradient in the clock gene and cell-cycle checkpoint kinase Wee1 expression along the gut. Chronobiol Int 2009, 26:607-620. 10.1080/07420520902924889, 19444744.
-
(2009)
Chronobiol Int
, vol.26
, pp. 607-620
-
-
Polidarova, L.1
Sotak, M.2
Sladek, M.3
Pacha, J.4
Sumova, A.5
-
32
-
-
79953779279
-
In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents
-
10.1007/s00280-010-1355-4, 20490800
-
Gravett AM, Liu WM, Krishna S, Chan WC, Haynes RK, Wilson NL, Dalgleish AG. In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents. Cancer Chemother Pharmacol 2011, 67:569-577. 10.1007/s00280-010-1355-4, 20490800.
-
(2011)
Cancer Chemother Pharmacol
, vol.67
, pp. 569-577
-
-
Gravett, A.M.1
Liu, W.M.2
Krishna, S.3
Chan, W.C.4
Haynes, R.K.5
Wilson, N.L.6
Dalgleish, A.G.7
-
33
-
-
0034125688
-
The G(2) DNA damage checkpoint targets both Wee1 and Cdc25
-
Raleigh JM, O'Connell MJ. The G(2) DNA damage checkpoint targets both Wee1 and Cdc25. J Cell Sci 2000, 113(Pt 10):1727-1736.
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 10
, pp. 1727-1736
-
-
Raleigh, J.M.1
O'Connell, M.J.2
-
34
-
-
34248185454
-
P53: guardian of the genome and policeman of the oncogenes
-
10.4161/cc.6.9.4211, 17457049
-
Efeyan A, Serrano M. p53: guardian of the genome and policeman of the oncogenes. Cell Cycle 2007, 6:1006-1010. 10.4161/cc.6.9.4211, 17457049.
-
(2007)
Cell Cycle
, vol.6
, pp. 1006-1010
-
-
Efeyan, A.1
Serrano, M.2
-
35
-
-
34247871501
-
P53: a two-faced cancer gene
-
10.1038/ncb0507-489, 17473858
-
Kastan MB, Berkovich E. p53: a two-faced cancer gene. Nat Cell Biol 2007, 9:489-491. 10.1038/ncb0507-489, 17473858.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 489-491
-
-
Kastan, M.B.1
Berkovich, E.2
-
36
-
-
77954641944
-
Radiation-induced cell death mechanisms
-
10.1007/s13277-010-0042-8, 20490962
-
Eriksson D, Stigbrand T. Radiation-induced cell death mechanisms. Tumour Biol 2010, 31:363-372. 10.1007/s13277-010-0042-8, 20490962.
-
(2010)
Tumour Biol
, vol.31
, pp. 363-372
-
-
Eriksson, D.1
Stigbrand, T.2
-
37
-
-
62449278758
-
Targeting p53 for enhanced radio- and chemo-sensitivity
-
10.1007/s10495-009-0330-1, 19259822
-
Lu C, El-Deiry WS. Targeting p53 for enhanced radio- and chemo-sensitivity. Apoptosis 2009, 14:597-606. 10.1007/s10495-009-0330-1, 19259822.
-
(2009)
Apoptosis
, vol.14
, pp. 597-606
-
-
Lu, C.1
El-Deiry, W.S.2
-
38
-
-
61749091373
-
Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis
-
10.1016/j.febslet.2009.02.028, 2666973, 19245811
-
Shi J, Hershey JW, Nelson MA. Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis. FEBS Lett 2009, 583:971-977. 10.1016/j.febslet.2009.02.028, 2666973, 19245811.
-
(2009)
FEBS Lett
, vol.583
, pp. 971-977
-
-
Shi, J.1
Hershey, J.W.2
Nelson, M.A.3
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