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Volumn 30, Issue 6, 2014, Pages 748-752

Inferring therapeutic targets from heterogeneous data: HKDC1 is a novel potential therapeutic target for cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HEXOKINASE; HK1 PROTEIN, HUMAN;

EID: 84897895149     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btt606     Document Type: Article
Times cited : (39)

References (23)
  • 1
    • 77953143235 scopus 로고    scopus 로고
    • Targeted cancer therapies
    • Aggarwal, S. (2010) Targeted cancer therapies. Nat. Rev. Drug Discov., 9, 427-428.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 427-428
    • Aggarwal, S.1
  • 2
    • 40849147041 scopus 로고    scopus 로고
    • Drug therapy: EGFR antagonists in cancer treatment
    • Ciardiello, F. and Tortora, G. (2008) Drug therapy: EGFR antagonists in cancer treatment. N. Eng. J. Med., 358, 1160-1174.
    • (2008) N. Eng. J. Med. , vol.358 , pp. 1160-1174
    • Ciardiello, F.1    Tortora, G.2
  • 3
    • 84862192766 scopus 로고    scopus 로고
    • ChEMBL: A large-scale bioactivity database for drug discovery
    • Gaulton, A. et al. (2012) ChEMBL: a large-scale bioactivity database for drug discovery. Nucleic Acids Res., 40, D1100-D1107.
    • (2012) Nucleic Acids Res. , vol.40
    • Gaulton, A.1
  • 4
    • 84871990400 scopus 로고    scopus 로고
    • Targeting the hallmarks of cancer: Towards a rational approach to next-generation cancer therapy., Cur
    • Hainaut, P. and Plymoth, A. (2013) Targeting the hallmarks of cancer: towards a rational approach to next-generation cancer therapy., Cur. Opin. Oncol., 25, 50-51.
    • (2013) Opin. Oncol. , vol.25 , pp. 50-51
    • Hainaut, P.1    Plymoth, A.2
  • 5
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. and Weinberg, R.A. (2011) Hallmarks of cancer: the next generation. Cell, 144, 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang, D.W. et al. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc., 4, 44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang, D.W.1
  • 7
    • 84859740873 scopus 로고    scopus 로고
    • RNA-Seq Atlas-A reference database for gene expression profiling in normal tissue by next-generation sequencing
    • Krupp, M. et al. (2012) RNA-Seq Atlas-a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics, 28, 1184-1185.
    • (2012) Bioinformatics , vol.28 , pp. 1184-1185
    • Krupp, M.1
  • 8
    • 84870857540 scopus 로고    scopus 로고
    • CDRUG: A web server for predicting anticancer activity of chemical compounds
    • Li, G.H. and Huang, J.F. (2012) CDRUG: a web server for predicting anticancer activity of chemical compounds. Bioinformatics, 28, 3334-3335.
    • (2012) Bioinformatics , vol.28 , pp. 3334-3335
    • Li, G.H.1    Huang, J.F.2
  • 9
    • 46249106990 scopus 로고    scopus 로고
    • Mapping and quantifying mammalian transcriptomes by RNA-Seq
    • Mortazavi, A. et al. (2008) Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat. Methods, 5, 621-628.
    • (2008) Nat. Methods , vol.5 , pp. 621-628
    • Mortazavi, A.1
  • 10
    • 33645306041 scopus 로고    scopus 로고
    • A loss-of-function RNA interference screen for molecular targets in cancer
    • Ngo, V.N. et al. (2006) A loss-of-function RNA interference screen for molecular targets in cancer. Nature, 441, 106-110.
    • (2006) Nature , vol.441 , pp. 106-110
    • Ngo, V.N.1
  • 11
    • 84863910171 scopus 로고    scopus 로고
    • CellMiner: A web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set
    • Reinhold, W.C. et al. (2012) CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set. Cancer Res., 72, 3499-3511.
    • (2012) Cancer Res. , vol.72 , pp. 3499-3511
    • Reinhold, W.C.1
  • 12
    • 0029891049 scopus 로고    scopus 로고
    • Glucose catabolism in cancer cells: Amplification of the gene encoding type II hexokinase
    • Rempel, A. et al. (1996) Glucose catabolism in cancer cells: amplification of the gene encoding type II hexokinase. Cancer Res., 56, 2468-2471.
    • (1996) Cancer Res. , vol.56 , pp. 2468-2471
    • Rempel, A.1
  • 13
    • 9244222261 scopus 로고    scopus 로고
    • Targeted cancer therapy
    • Sawyers, C. (2004) Targeted cancer therapy. Nature, 432, 294-297.
    • (2004) Nature , vol.432 , pp. 294-297
    • Sawyers, C.1
  • 14
    • 84868309107 scopus 로고    scopus 로고
    • The transcriptional landscape and mutational profile of lung adenocarcinoma
    • Seo, J.S. et al. (2012) The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res., 22, 2109-2119.
    • (2012) Genome Res. , vol.22 , pp. 2109-2119
    • Seo, J.S.1
  • 15
    • 84867315140 scopus 로고    scopus 로고
    • An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer
    • Sethi, G. et al. (2012) An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer. PLoS One, 7, e47086B.
    • (2012) PLoS One , vol.7
    • Sethi, G.1
  • 16
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumour cell line anticancer drug screen
    • Shoemaker, R.H. (2006) The NCI60 human tumour cell line anticancer drug screen. Nat. Rev. Cancer, 6, 813-823.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 813-823
    • Shoemaker, R.H.1
  • 17
    • 33746207761 scopus 로고    scopus 로고
    • Sequence biases in large scale gene expression profiling data
    • Siddiqui, A.S. et al. (2006) Sequence biases in large scale gene expression profiling data. Nucleic Acids Res., 34, e83.
    • (2006) Nucleic Acids Res. , vol.34
    • Siddiqui, A.S.1
  • 18
    • 84855792427 scopus 로고    scopus 로고
    • Cancer statistics, 2012
    • Siegel, R. et al. (2012) Cancer statistics, 2012. CA Cancer J. Clin., 62, 10-29.
    • (2012) CA Cancer J. Clin. , vol.62 , pp. 10-29
    • Siegel, R.1
  • 19
    • 77949967131 scopus 로고    scopus 로고
    • Targeting metabolic transformation for cancer therapy
    • Tennant, D.A. et al. (2010) Targeting metabolic transformation for cancer therapy. Nat. Rev. Cancer, 10, 267-277.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 267-277
    • Tennant, D.A.1
  • 20
    • 84863012484 scopus 로고    scopus 로고
    • Identification of molecular vulnerabilities in human multiple myeloma cells by RNA interference lethality screening of the druggable genome
    • Tiedemann, R.E. et al. (2012) Identification of molecular vulnerabilities in human multiple myeloma cells by RNA interference lethality screening of the druggable genome. Cancer Res., 72, 757-768.
    • (2012) Cancer Res. , vol.72 , pp. 757-768
    • Tiedemann, R.E.1
  • 21
    • 79957925832 scopus 로고    scopus 로고
    • Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer
    • Tugues, S. et al. (2011) Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer. Mol. Aspects Med., 32, 88-111.
    • (2011) Mol. Aspects Med. , vol.32 , pp. 88-111
    • Tugues, S.1
  • 22
    • 0038714272 scopus 로고    scopus 로고
    • Isozymes of mammalian hexokinase: Structure, subcellular localization and metabolic function
    • Wilson, J.E. (2003) Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function. J. Exp. Biol., 206, 2049-2057.
    • (2003) J. Exp. Biol. , vol.206 , pp. 2049-2057
    • Wilson, J.E.1
  • 23
    • 79951699777 scopus 로고    scopus 로고
    • Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme
    • Wolf, A. et al. (2011) Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme. J. Exp. Med., 208, 313-326.
    • (2011) J. Exp. Med. , vol.208 , pp. 313-326
    • Wolf, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.