High-sensitivity cardiac troponin t predicts non-cardiac mortality in heart failure

Circulation Journal

Volumn 78, Issue 4, 2014, Pages 890-895

  Nakamura, Yuichi ^a   Yoshihisa, Akiomi ^a   Takiguchi, Mai ^a   Shimizu, Takeshi ^a   Yamauchi, Hiroyuki ^a   Iwaya, Shoji ^a   Owada, Takashi ^a   Miyata, Makiko ^a   Abe, Satoshi ^a   Sato, Takamasa ^a   Suzuki, Satoshi ^a   Oikawa, Masayoshi ^a   Kobayashi, Atsushi ^a   Yamaki, Takayoshi ^a   Sugimoto, Koichi ^a   Kunii, Hiroyuki ^a   Nakazato, Kazuhiko ^a   Suzuki, Hitoshi ^a   Saitoh, Shu Ichi ^a   Takeishi, Yasuchika ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Cardio renal function; High sensitivity troponin T; Non cardiac death; Prognosis

Indexed keywords

CYSTATIN C; HEMOGLOBIN; HIGH SENSITIVITY CARDIAC TROPONIN T; TROPONIN T; UNCLASSIFIED DRUG;

AGED; ANEMIA; ARTICLE; CARDIOVASCULAR MORTALITY; CHEMILUMINESCENCE IMMUNOASSAY; ECHOCARDIOGRAPHY; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HEART DEATH; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE VOLUME; HEART VENTRICLE HYPERTROPHY; HUMAN; IMMUNORADIOMETRIC ASSAY; KIDNEY DYSFUNCTION; LEFT VENTRICULAR SYSTOLIC DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; RETROSPECTIVE STUDY; RISK FACTOR;

AGED; AGED, 80 AND OVER; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; TROPONIN T;

EID: 84897855379     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-13-1372     Document Type: Article

References (38)

1. Thygesen K, Alpert JS, White HD, Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction, Jaffe AS, Apple FS, et al. Universal definition of myocardial infarction. Circulation 2007; 116: 2634-2653.
2. Mueller M, Vafaie M, Biener M, Giannitsis E, Katus HA. Cardiac troponin T: From diagnosis of myocardial infarction to cardiovascular risk prediction. Circ J 2013; 77: 1653-1661.
3. Peacock WF, De Marco T, Fonarow GC, Diercks D, Wynne J, Apple FS, et al. Cardiac troponin and outcome in acute heart failure. N Engl J Med 2008; 358: 2117-2126.
4. Arenja N, Reichlin T, Drexler B, Oshima S, Denhaerynck K, Haaf P, et al. Sensitive cardiac troponin in the diagnosis and risk stratifca-tion of acute heart failure. J Intern Med 2012; 271: 598-607.
5. Ather S, Hira RS, Shenoy M, Fatemi O, Deswal A, Aguilar D, et al. Recurrent low-level troponin I elevation is a worse prognostic indicator than occasional injury pattern in patients hospitalized with heart failure. Int J Cardiol 2013; 166: 394-398.
6. Latini R, Masson S, Anand IS, Missov E, Carlson M, Vago T, et al. Prognostic value of very low plasma concentrations of troponin T in patients with stable chronic heart failure. Circulation 2007; 116: 1242-1249.
7. Miller WL, Hartman KA, Burritt MF, Grill DE, Jaffe AS. Profiles of serial changes in cardiac troponin T concentrations and outcome in ambulatory patients with chronic heart failure. J Am Coll Cardiol 2009; 54: 1715-1721.
8. Masson S, Anand I, Favero C, Barlera S, Vago T, Bertocchi F, et al. Serial measurement of cardiac troponin T using a highly sensitive assay in patients with chronic heart failure: Data from 2 large randomized clinical trials. Circulation 2012; 125: 280-288.
9. Egstrup M, Schou M, Tuxen CD, Kistorp CN, Hildebrandt PR, Gustafsson F, et al. Prediction of outcome by highly sensitive tropo-nin T in outpatients with chronic systolic left ventricular heart failure. Am J Cardiol 2012; 110: 552-557.
10. de Antonio M, Lupon J, Galan A, Vila J, Urrutia A, Bayes-Genis A. Combined use of high-sensitivity cardiac troponin T and N-terminal pro-B type natriuretic peptide improves measurements of performance over established mortality risk factors in chronic heart failure. Am Heart J 2012; 163: 821-828.
11. Kelley WE, Januzzi JL, Christenson RH. Increases of cardiac troponin in conditions other than acute coronary syndrome and heart failure. Clin Chem 2009; 55: 2098-2112.
12. Agewall S, Giannitsis E, Jernberg T, Katus H. Troponin elevation in coronary vs. non-coronary disease. Eur Heart J 2011; 32: 404-411.
13. McKee PA, Castelli WP, McNamara PM, Kannel WB. The natural history of congestive heart failure: The Framingham study. N Engl J Med 1971; 285: 1441-1446.
14. Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, et al. Using standardized serum creatinine values in the modifcation of diet in renal disease study equation for estimating glomerular fltra-tion rate. Ann Intern Med 2006; 145: 247-254.
15. McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 2012; 14: 803-869.
16. National Institutes of Health, National Heart, Lung, and Blood Institute. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Workshop Report. 2013. http://goldcopd.org/Guidelines/guidelines-resources.html. (accessed October 10, 2013).
17. Celli BR, MacNee W, Force AET. Standards for the diagnosis and treatment of patients with COPD: A summary of the ATS/ERS position paper. Eur Respir J 2004; 23: 932-946.
18. Mingels A, Jacobs L, Michielsen E, Swaanenburg J, Wodzig W, van Dieijen-Visser M. Reference population and marathon runner sera assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and I assays. Clin Chem 2009; 55: 101-108.
19. Rudski LG, Lai WW, Aflalo J, Hua L, Handschumacher MD, Chandrasekaran K, et al. Guidelines for the echocardiographic assessment of the right heart in adults: A report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 2010; 23: 685-713.
20. de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA 2010; 304: 2503-2512.
21. deFilippi C, Seliger SL, Kelley W, Duh SH, Hise M, Christenson RH, et al. Interpreting cardiac troponin results from high-sensitivity assays in chronic kidney disease without acute coronary syndrome. Clin Chem 2012; 58: 1342-1351.
22. Mehta NJ, Khan IA, Gupta V, Jani K, Gowda RM, Smith PR. Cardiac troponin I predicts myocardial dysfunction and adverse outcome in septic shock. Int J Cardiol 2004; 95: 13-17.
23. Kerr G, Ray G, Wu O, Stott DJ, Langhorne P. Elevated troponin after stroke: A systematic review. Cerebrovasc Dis 2009; 28: 220-226.
24. Iser DM, Thompson AJ, Sia KK, Yeomans ND, Chen RY. Prospective study of cardiac troponin I release in patients with upper gastrointestinal bleeding. J Gastroenterol Hepatol 2008; 23: 938-942.
25. Neukamm AM, Hoiseth AD, Hagve TA, Soyseth V, Omland T. High-sensitivity cardiac troponin T levels are increased in stable COPD. Heart 2013; 99: 382-387.
26. Randby A, Namtvedt SK, Einvik G, Hrubos-Strom H, Hagve TA, Somers VK, et al. Obstructive sleep apnea is associated with increased high-sensitivity cardiac troponin T levels. Chest 2012; 142: 639-646.
27. Yoshihisa A, Suzuki S, Miyata M, Yamaki T, Sugimoto K, Kunii H, et al. 'A single night' benefcial effects of adaptive servo-ventilation on cardiac overload, sympathetic nervous activity, and myocardial damage in patients with chronic heart failure and sleep-disordered breathing. Circ J 2012; 76: 2153-2158.
28. Bajwa EK, Boyce PD, Januzzi JL, Gong MN, Thompson BT, Christiani DC. Biomarker evidence of myocardial cell injury is associated with mortality in acute respiratory distress syndrome. Crit Care Med 2007; 35: 2484-2490.
29. Pruszczyk P, Bochowicz A, Torbicki A, Szulc M, Kurzyna M, Fijalkowska A, et al. Cardiac troponin T monitoring identifies high-risk group of normotensive patients with acute pulmonary embolism. Chest 2003; 123: 1947-1952.
30. Kline JA, Hernandez-Nino J, Rose GA, Norton HJ, Camargo CA Jr. Surrogate markers for adverse outcomes in normotensive patients with pulmonary embolism. Crit Care Med 2006; 34: 2773-2780.
31. Iversen K, Kober L, Gotze JP, Dalsgaard M, Nielsen H, Boesgaard S, et al. Troponin T is a strong marker of mortality in hospitalized patients. Int J Cardiol 2013; 168: 818-824.
32. Sinden NJ, Stockley RA. Systemic infammation and comorbidity in COPD: A result of 'overspill' of inflammatory mediators from the lungs? Review of the evidence. Thorax 2010; 65: 930-936.
33. Biasucci LM, Porto I, Di Vito L, De Maria GL, Leone AM, Tinelli G, et al. Differences in microparticle release in patients with acute coronary syndrome and stable angina. Circ J 2012; 76: 2174-2182.
34. Saunders JT, Nambi V, de Lemos JA, Chambless LE, Virani SS, Boerwinkle E, et al. Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study. Circulation 2011; 123: 1367-1376.
35. White HD. Pathobiology of troponin elevations: Do elevations occur with myocardial ischemia as well as necrosis? J Am Coll Cardiol 2011; 57: 2406-2408.
36. Fromm RE Jr. Cardiac troponins in the intensive care unit: Common causes of increased levels and interpretation. Crit Care Med 2007; 35: 584-588.
37. Roongsritong C, Warraich I, Bradley C. Common causes of troponin elevations in the absence of acute myocardial infarction: Incidence and clinical significance. Chest 2004; 125: 1877-1884.
38. Jespersen CM, Fischer Hansen J. Myocardial stress in patients with acute cerebrovascular events. Cardiology 2008; 110: 123-128.