Critical models for the anemia of inflammation

Blood

Volumn 123, Issue 8, 2014, Pages 1124-1125

  Fraenkel, Paula G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANEMIA; DISEASE MODEL; HUMAN; INFLAMMATION; NONHUMAN; NOTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ANEMIA; ANIMALS; BRUCELLA ABORTUS; BRUCELLOSIS; FEMALE; HEPCIDINS; HUMANS; INFLAMMATION; INTERLEUKIN-6; MALE;

EID: 84897850976     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-01-546994     Document Type: Note

References (11)

1. Kim A, Fung E, Parikh SG, et al. A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin. Blood. 2014;123(8):1129-1136.
2. Gardenghi S, Renaud TM, Meloni A, et al. Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus. Blood. 2014;123(8):1137-1145.
3. van Iperen CE, Gaillard CA, Kraaijenhagen RJ, Braam BG, Marx JJ, van de Wiel A. Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients. Crit Care Med. 2000;28(8):2773-2778.
4. Corwin HL, Gettinger A, Pearl RG, et al. The CRIT Study: anemia and blood transfusion in the critically ill - current clinical practice in the United States. Crit Care Med. 2004;32(1):39-52. (Pubitemid 38125561)
5. Ganz T, Nemeth E. Hepcidin and iron homeostasis. Biochim Biophys Acta. 2012;1823(9):1434-1443.
6. Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113(9):1271-1276. (Pubitemid 39069926)
7. Wrighting DM, Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood. 2006;108(9):3204-3209.
8. Song SN, Tomosugi N, Kawabata H, Ishikawa T, Nishikawa T, Yoshizaki K. Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease. Blood. 2010;116(18):3627-3634.
9. Sasu BJ, Cooke KS, Arvedson TL, et al. Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of infl ammation-induced anemia. Blood. 2010;115(17):3616-3624.
10. Zhen AW, Nguyen NH, Gibert Y, et al. The small molecule, genistein, increases hepcidin expression in human hepatocytes. Hepatology. 2013;58(4):1315-1325.
11. Rivera S, Ganz T. Animal models of anemia of inflammation. Semin Hematol. 2009;46(4):351-357.