-
1
-
-
80054865852
-
TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses
-
doi: 10.1111/j.1600-065X.2011.01054.x
-
Burkly LC, Michaelson JS, Zheng TS. TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses. Immunol Rev (2011) 244:99-114. doi: 10.1111/j.1600-065X.2011.01054.x.
-
(2011)
Immunol Rev
, vol.244
, pp. 99-114
-
-
Burkly, L.C.1
Michaelson, J.S.2
Zheng, T.S.3
-
2
-
-
84885115695
-
The TWEAK-Fn14 system as a potential drug target
-
doi:10.1111/bph.12337
-
Wajant H. The TWEAK-Fn14 system as a potential drug target. Br J Pharmacol (2013) 170:748-64. doi:10.1111/bph.12337.
-
(2013)
Br J Pharmacol
, vol.170
, pp. 748-764
-
-
Wajant, H.1
-
3
-
-
0141815764
-
TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation
-
doi:10.1074/jbc.M304266200
-
Saitoh T, Nakayama M, Nakano H, Yagita H, Yamamoto N, Yamaoka S. TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. J Biol Chem (2003) 278:36005-12. doi:10.1074/jbc.M304266200.
-
(2003)
J Biol Chem
, vol.278
, pp. 36005-36012
-
-
Saitoh, T.1
Nakayama, M.2
Nakano, H.3
Yagita, H.4
Yamamoto, N.5
Yamaoka, S.6
-
4
-
-
84858627919
-
Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors
-
doi:10.1126/scisignal.2001878
-
Varfolomeev E, Goncharov T, Maecker H, Zobel K, Kömüves LG, Deshayes K, et al. Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors. Sci Signal (2012) 5(216):ra22. doi:10.1126/scisignal.2001878.
-
(2012)
Sci Signal
, vol.5
, Issue.216
-
-
Varfolomeev, E.1
Goncharov, T.2
Maecker, H.3
Zobel, K.4
Kömüves, L.G.5
Deshayes, K.6
-
5
-
-
18244380611
-
A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis
-
doi:10.1016/S1074-7613(01)00232-1
-
Wiley SR, Cassiano L, Lofton T, Davis-Smith T, Winkles JA, Lindner V, et al. A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity (2001) 15:837-46. doi:10.1016/S1074-7613(01)00232-1.
-
(2001)
Immunity
, vol.15
, pp. 837-846
-
-
Wiley, S.R.1
Cassiano, L.2
Lofton, T.3
Davis-Smith, T.4
Winkles, J.A.5
Lindner, V.6
-
6
-
-
0038242506
-
TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors
-
doi:10.1016/S0006-291X(03)00852-0
-
Han S, Yoon K, Lee K, Kim K, Jang H, Lee NK, et al. TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors. Biochem Biophys Res Commun (2003) 305:789-96. doi:10.1016/S0006-291X(03)00852-0.
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 789-796
-
-
Han, S.1
Yoon, K.2
Lee, K.3
Kim, K.4
Jang, H.5
Lee, N.K.6
-
7
-
-
0038708366
-
The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation
-
doi:10.1042/BJ20021730
-
Brown SA, Richards CM, Hanscom HN, Feng SL, Winkles JA. The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. Biochem J (2003) 371:395-403. doi:10.1042/BJ20021730.
-
(2003)
Biochem J
, vol.371
, pp. 395-403
-
-
Brown, S.A.1
Richards, C.M.2
Hanscom, H.N.3
Feng, S.L.4
Winkles, J.A.5
-
8
-
-
61449148439
-
TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta-activated kinase 1
-
doi:10.4049/jimmunol.0803357
-
Kumar M, Makonchuk DY, Li H, Mittal A, Kumar A. TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta-activated kinase 1. J Immunol (2009) 182:2439-48. doi:10.4049/jimmunol.0803357.
-
(2009)
J Immunol
, vol.182
, pp. 2439-2448
-
-
Kumar, M.1
Makonchuk, D.Y.2
Li, H.3
Mittal, A.4
Kumar, A.5
-
9
-
-
84881249513
-
The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasion via tumor necrosis factor receptor-associated factor 2
-
doi:10.1074/jbc.M113.468686
-
Fortin Ensign SP, Mathews IT, Eschbacher JM, Loftus JC, Symons MH, Tran NL. The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasion via tumor necrosis factor receptor-associated factor 2. J Biol Chem (2013) 288:21887-2897. doi:10.1074/jbc.M113.468686.
-
(2013)
J Biol Chem
, vol.288
, pp. 21887-22897
-
-
Fortin Ensign, S.P.1
Mathews, I.T.2
Eschbacher, J.M.3
Loftus, J.C.4
Symons, M.H.5
Tran, N.L.6
-
10
-
-
33750300516
-
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome
-
doi:10.1158/0008-5472.CAN-06-0418
-
Tran NL, Mcdonough WS, Savitch BA, Fortin SP, Winkles JA, Symons M, et al. Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome. Cancer Res (2006) 66:9535-42. doi:10.1158/0008-5472.CAN-06-0418.
-
(2006)
Cancer Res
, vol.66
, pp. 9535-9542
-
-
Tran, N.L.1
Mcdonough, W.S.2
Savitch, B.A.3
Fortin, S.P.4
Winkles, J.A.5
Symons, M.6
-
11
-
-
84864011846
-
Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells
-
doi:10.1158/1541-7786.MCR-11-0616
-
Fortin SP, Ennis MJ, Schumacher CA, Zylstra-Diegel CR, Williams BO, Ross JT, et al. Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells. Mol Cancer Res (2012) 10:958-68. doi:10.1158/1541-7786.MCR-11-0616.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 958-968
-
-
Fortin, S.P.1
Ennis, M.J.2
Schumacher, C.A.3
Zylstra-Diegel, C.R.4
Williams, B.O.5
Ross, J.T.6
-
12
-
-
0031465594
-
TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis
-
doi:10.1074/jbc.272.51.32401
-
Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, et al. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J Biol Chem (1997) 272:32401-10. doi:10.1074/jbc.272.51.32401.
-
(1997)
J Biol Chem
, vol.272
, pp. 32401-32410
-
-
Chicheportiche, Y.1
Bourdon, P.R.2
Xu, H.3
Hsu, Y.M.4
Scott, H.5
Hession, C.6
-
13
-
-
0034613732
-
Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity
-
doi:10.1084/jem.192.9.1373
-
Nakayama M, Kayagaki N, Yamaguchi N, Okumura K, Yagita H. Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity. J Exp Med (2000) 192:1373-80. doi:10.1084/jem.192.9.1373.
-
(2000)
J Exp Med
, vol.192
, pp. 1373-1380
-
-
Nakayama, M.1
Kayagaki, N.2
Yamaguchi, N.3
Okumura, K.4
Yagita, H.5
-
14
-
-
77952892382
-
Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway
-
doi:10.1074/jbc.M110.131979
-
Brown SA, Ghosh A, Winkles JA. Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway. J Biol Chem (2010) 285:17432-41. doi:10.1074/jbc.M110.131979.
-
(2010)
J Biol Chem
, vol.285
, pp. 17432-17441
-
-
Brown, S.A.1
Ghosh, A.2
Winkles, J.A.3
-
15
-
-
77956406117
-
Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway
-
doi:10.4049/jimmunol.0903555
-
Roos C, Wicovsky A, Müller N, Salzmann S, Rosenthal T, Kalthoff H, et al. Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway. J Immunol (2010) 185:1593-605. doi:10.4049/jimmunol.0903555.
-
(2010)
J Immunol
, vol.185
, pp. 1593-1605
-
-
Roos, C.1
Wicovsky, A.2
Müller, N.3
Salzmann, S.4
Rosenthal, T.5
Kalthoff, H.6
-
16
-
-
47549097367
-
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFα
-
doi:10.1083/jcb.200801010
-
Vince JE, Chau D, Callus B, Wong WWL, Hawkins CJ, Schneider P, et al. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFα. J Cell Biol (2008) 182:171-84. doi:10.1083/jcb.200801010.
-
(2008)
J Cell Biol
, vol.182
, pp. 171-184
-
-
Vince, J.E.1
Chau, D.2
Callus, B.3
Wong, W.W.L.4
Hawkins, C.J.5
Schneider, P.6
-
17
-
-
70350007940
-
TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling
-
doi:10.1038/cdd.2009.80)
-
Wicovsky A, Salzmann S, Roos C, Ehrenschwender M, Rosenthal T, Siegmund D, et al. TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling. Cell Death Differ (2009) 16:1445-59. doi:10.1038/cdd.2009.80).
-
(2009)
Cell Death Differ
, vol.16
, pp. 1445-1459
-
-
Wicovsky, A.1
Salzmann, S.2
Roos, C.3
Ehrenschwender, M.4
Rosenthal, T.5
Siegmund, D.6
-
18
-
-
83955161650
-
Inhibition of TNF-induced IL-6 by the TWEAK-Fn14 interaction in rheumatoid arthritis fibroblast like synoviocytes
-
doi:10.1016/j.cellimm.2011.09.004
-
Yamana J, Morand EF, Manabu T, Sunahori K, Takasugi K, Makino H, et al. Inhibition of TNF-induced IL-6 by the TWEAK-Fn14 interaction in rheumatoid arthritis fibroblast like synoviocytes. Cell Immunol (2012) 272:293-8. doi:10.1016/j.cellimm.2011.09.004.
-
(2012)
Cell Immunol
, vol.272
, pp. 293-298
-
-
Yamana, J.1
Morand, E.F.2
Manabu, T.3
Sunahori, K.4
Takasugi, K.5
Makino, H.6
-
19
-
-
84881511197
-
The rise of soluble TWEAK levels in severely obese subjects after bariatric surgery may affect adipocyte-cytokine production induced by TNFα
-
doi:10.1210/jc.2012-4177
-
Maymó-Masip E, Fernández-Veledo S, Garcia España A, Vázquez-Carballo A, Tinahones FJ, et al. The rise of soluble TWEAK levels in severely obese subjects after bariatric surgery may affect adipocyte-cytokine production induced by TNFα. J Clin Endocrinol Metab (2013) 98:1323-33. doi:10.1210/jc.2012-4177.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 1323-1333
-
-
Maymó-Masip, E.1
Fernández-Veledo, S.2
Garcia España, A.3
Vázquez-Carballo, A.4
Tinahones, F.J.5
-
20
-
-
84883401846
-
TWEAK inhibits TRAF2-mediated CD40 signaling by destabilization of CD40 signaling complexes
-
doi:10.4049/jimmunol.1202899
-
Salzmann S, Lang I, Rosenthal A, Schäfer V, Weisenberger D, Carmona Arana JA, et al. TWEAK inhibits TRAF2-mediated CD40 signaling by destabilization of CD40 signaling complexes. J Immunol (2013) 191:2308-18. doi:10.4049/jimmunol.1202899.
-
(2013)
J Immunol
, vol.191
, pp. 2308-2318
-
-
Salzmann, S.1
Lang, I.2
Rosenthal, A.3
Schäfer, V.4
Weisenberger, D.5
Carmona Arana, J.A.6
-
21
-
-
77950352082
-
Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation
-
doi:10.1016/j.molcel.2010.03.009
-
Zheng C, Kabaleeswaran V, Wang Y, Cheng G, Wu H. Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation. Mol Cell (2010) 38:101-13. doi:10.1016/j.molcel.2010.03.009.
-
(2010)
Mol Cell
, vol.38
, pp. 101-113
-
-
Zheng, C.1
Kabaleeswaran, V.2
Wang, Y.3
Cheng, G.4
Wu, H.5
-
22
-
-
0345791504
-
Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation
-
doi:10.1074/jbc.M310969200
-
Fotin-Mleczek M, Henkler F, Hausser A, Glauner H, Samel D, Graness A, et al. Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation. J Biol Chem (2004) 279:677-85. doi:10.1074/jbc.M310969200.
-
(2004)
J Biol Chem
, vol.279
, pp. 677-685
-
-
Fotin-Mleczek, M.1
Henkler, F.2
Hausser, A.3
Glauner, H.4
Samel, D.5
Graness, A.6
-
23
-
-
80054854922
-
Non-canonical NF-κB signaling activation and regulation: principles and perspectives
-
doi:10.1111/j.1600-065X.2011.01059.x
-
Razani B, Reichardt AD, Cheng G. Non-canonical NF-κB signaling activation and regulation: principles and perspectives. Immunol Rev (2011) 244:44-54. doi:10.1111/j.1600-065X.2011.01059.x.
-
(2011)
Immunol Rev
, vol.244
, pp. 44-54
-
-
Razani, B.1
Reichardt, A.D.2
Cheng, G.3
-
24
-
-
0032508414
-
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
doi:10.1126/science.281.5383.1680
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science (1998) 281:1680-3. doi:10.1126/science.281.5383.1680.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
25
-
-
0032698901
-
TRAF1 is a TNF inducible regulator of NF-kappaB activation
-
doi:10.1016/S0014-5793(99)01356-3
-
Carpentier I, Beyaert R. TRAF1 is a TNF inducible regulator of NF-kappaB activation. FEBS Lett (1999) 460:246-50. doi:10.1016/S0014-5793(99)01356-3.
-
(1999)
FEBS Lett
, vol.460
, pp. 246-250
-
-
Carpentier, I.1
Beyaert, R.2
-
26
-
-
0033516570
-
The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase
-
doi:10.1074/jbc.274.27.19368
-
Schwenzer R, Siemienski K, Liptay S, Schubert G, Peters N, Scheurich P, et al. The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase. J Biol Chem (1999) 274:19368-74. doi:10.1074/jbc.274.27.19368.
-
(1999)
J Biol Chem
, vol.274
, pp. 19368-19374
-
-
Schwenzer, R.1
Siemienski, K.2
Liptay, S.3
Schubert, G.4
Peters, N.5
Scheurich, P.6
-
27
-
-
5644302162
-
Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase
-
doi:10.1016/j.immuni.2004.08.009
-
Ramakrishnan P, Wang W, Wallach D. Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity (2004) 21:477-89. doi:10.1016/j.immuni.2004.08.009.
-
(2004)
Immunity
, vol.21
, pp. 477-489
-
-
Ramakrishnan, P.1
Wang, W.2
Wallach, D.3
-
28
-
-
0033966264
-
Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis
-
doi:10.1016/S0014-5793(00)01206-0
-
Irmler M, Steiner V, Ruegg C, Wajant H, Tschopp J. Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis. FEBS Lett (2000) 468:129-33. doi:10.1016/S0014-5793(00)01206-0.
-
(2000)
FEBS Lett
, vol.468
, pp. 129-133
-
-
Irmler, M.1
Steiner, V.2
Ruegg, C.3
Wajant, H.4
Tschopp, J.5
-
29
-
-
0035896644
-
TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis
-
doi:10.1074/jbc.M009450200
-
Leo E, Deveraux QL, Buchholtz C, Welsh K, Matsuzawa S, Stennicke HR, et al. TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis. J Biol Chem (2001) 276:8087-93. doi:10.1074/jbc.M009450200.
-
(2001)
J Biol Chem
, vol.276
, pp. 8087-8093
-
-
Leo, E.1
Deveraux, Q.L.2
Buchholtz, C.3
Welsh, K.4
Matsuzawa, S.5
Stennicke, H.R.6
-
30
-
-
0034803045
-
Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death
-
doi:10.1006/bbrc.2001.4369
-
Jang HD, Chung YM, Baik JH, Choi YG, Park IS, Jung YK, et al. Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death. Biochem Biophys Res Commun (2001) 281:499-505. doi:10.1006/bbrc.2001.4369.
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 499-505
-
-
Jang, H.D.1
Chung, Y.M.2
Baik, J.H.3
Choi, Y.G.4
Park, I.S.5
Jung, Y.K.6
-
31
-
-
8744244173
-
Mass spectrometric analysis of tumor necrosis factor receptor-associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2
-
doi:10.1002/pmic.200401000
-
Lee JS, Hong US, Lee TH, Yoon SK, Yoon JB. Mass spectrometric analysis of tumor necrosis factor receptor-associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2. Proteomics (2004) 4:3376-82. doi:10.1002/pmic.200401000.
-
(2004)
Proteomics
, vol.4
, pp. 3376-3382
-
-
Lee, J.S.1
Hong, U.S.2
Lee, T.H.3
Yoon, S.K.4
Yoon, J.B.5
-
32
-
-
84855283949
-
Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) to fibroblast growth factor inducible 14 (Fn14)
-
doi:10.1074/jbc.M111.287656
-
Fick A, Lang I, Schäfer V, Seher A, Trebing J, Weisenberger D, et al. Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) to fibroblast growth factor inducible 14 (Fn14). J Biol Chem (2012) 287:484-95. doi:10.1074/jbc.M111.287656.
-
(2012)
J Biol Chem
, vol.287
, pp. 484-495
-
-
Fick, A.1
Lang, I.2
Schäfer, V.3
Seher, A.4
Trebing, J.5
Weisenberger, D.6
-
33
-
-
84875138229
-
The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors
-
doi:10.1371/journal.pone.0059292
-
Rauert-Wunderlich H, Siegmund D, Maier E, Giner T, Bargou RC, Wajant H, et al. The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors. PLoS One (2013) 8:e59292. doi:10.1371/journal.pone.0059292.
-
(2013)
PLoS One
, vol.8
-
-
Rauert-Wunderlich, H.1
Siegmund, D.2
Maier, E.3
Giner, T.4
Bargou, R.C.5
Wajant, H.6
-
34
-
-
64749098830
-
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
-
doi:10.1038/nature07884
-
Soucy TA, Smith PG, Milhollen MA, Berger AJ, Gavin JM, Adhikari S, et al. An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature (2009) 458:732-6. doi:10.1038/nature07884.
-
(2009)
Nature
, vol.458
, pp. 732-736
-
-
Soucy, T.A.1
Smith, P.G.2
Milhollen, M.A.3
Berger, A.J.4
Gavin, J.M.5
Adhikari, S.6
-
35
-
-
84856641109
-
NF-κB, the first quarter-century: remarkable progress and outstanding questions
-
doi:10.1101/gad.183434.111
-
Hayden MS, Ghosh S. NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev (2012) 26:203-34. doi:10.1101/gad.183434.111.
-
(2012)
Genes Dev
, vol.26
, pp. 203-234
-
-
Hayden, M.S.1
Ghosh, S.2
-
36
-
-
0032818286
-
Structure of the murine TRAF1 gene
-
doi:10.1016/S0161-5890(99)00075-9
-
Dunn IF, Geha RS, Tsitsikov EN. Structure of the murine TRAF1 gene. Mol Immunol (1999) 36:611-7. doi:10.1016/S0161-5890(99)00075-9.
-
(1999)
Mol Immunol
, vol.36
, pp. 611-617
-
-
Dunn, I.F.1
Geha, R.S.2
Tsitsikov, E.N.3
-
37
-
-
34547138171
-
NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis
-
doi:10.1182/blood-2006-11-058446
-
Zhang B, Wang Z, Li T, Tsitsikov EN, Ding HF. NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis. Blood (2007) 110:743-51. doi:10.1182/blood-2006-11-058446.
-
(2007)
Blood
, vol.110
, pp. 743-751
-
-
Zhang, B.1
Wang, Z.2
Li, T.3
Tsitsikov, E.N.4
Ding, H.F.5
-
38
-
-
33645785083
-
NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity
-
Sánchez-Valdepeñas C, Martín AG, Ramakrishnan P, Wallach D, Fresno M. NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. J Immunol (2006) 176:4666-74.
-
(2006)
J Immunol
, vol.176
, pp. 4666-4674
-
-
Sánchez-Valdepeñas, C.1
Martín, A.G.2
Ramakrishnan, P.3
Wallach, D.4
Fresno, M.5
-
39
-
-
0037497184
-
A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression
-
doi:10.1038/nature01648
-
Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature (2003) 423:659-63. doi:10.1038/nature01648.
-
(2003)
Nature
, vol.423
, pp. 659-663
-
-
Anest, V.1
Hanson, J.L.2
Cogswell, P.C.3
Steinbrecher, K.A.4
Strahl, B.D.5
Baldwin, A.S.6
-
40
-
-
0038511129
-
Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression
-
doi:10.1038/nature01576
-
Yamamoto Y, Verma UN, Prajapati S, Kwak YT, Gaynor RB. Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. Nature (2003) 423:655-9. doi:10.1038/nature01576.
-
(2003)
Nature
, vol.423
, pp. 655-659
-
-
Yamamoto, Y.1
Verma, U.N.2
Prajapati, S.3
Kwak, Y.T.4
Gaynor, R.B.5
-
41
-
-
33846323310
-
A fourth IkappaB protein within the NF-kappaB signaling module
-
doi:10.1016/j.cell.2006.12.033
-
Basak S, Kim H, Kearns JD, Tergaonkar V, O'Dea E, Werner SL, et al. A fourth IkappaB protein within the NF-kappaB signaling module. Cell (2007) 128:369-81. doi:10.1016/j.cell.2006.12.033.
-
(2007)
Cell
, vol.128
, pp. 369-381
-
-
Basak, S.1
Kim, H.2
Kearns, J.D.3
Tergaonkar, V.4
O'Dea, E.5
Werner, S.L.6
-
42
-
-
79952498248
-
TNFR1-induced activation of the classical NF-κB pathway
-
doi:10.1111/j.1742-4658.2011.08015.x
-
Wajant H, Scheurich P. TNFR1-induced activation of the classical NF-κB pathway. FEBS J (2011) 278:862-76. doi:10.1111/j.1742-4658.2011.08015.x.
-
(2011)
FEBS J
, vol.278
, pp. 862-876
-
-
Wajant, H.1
Scheurich, P.2
-
43
-
-
65049086930
-
Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation
-
doi:10.1038/onc.2009.29
-
Wicovsky A, Henkler F, Salzmann S, Scheurich P, Kneitz C, Wajant H. Tumor necrosis factor receptor-associated factor-1 enhances proinflammatory TNF receptor-2 signaling and modifies TNFR1-TNFR2 cooperation. Oncogene (2009) 28:1769-81. doi:10.1038/onc.2009.29.
-
(2009)
Oncogene
, vol.28
, pp. 1769-1781
-
-
Wicovsky, A.1
Henkler, F.2
Salzmann, S.3
Scheurich, P.4
Kneitz, C.5
Wajant, H.6
-
44
-
-
84858337114
-
Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL-and CD95-mediated apoptosis of glioblastoma cells
-
doi:10.1038/onc.2011.333
-
Jennewein C, Karl S, Baumann B, Micheau O, Debatin KM, Fulda S. Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL-and CD95-mediated apoptosis of glioblastoma cells. Oncogene (2012) 31:1468-74. doi:10.1038/onc.2011.333.
-
(2012)
Oncogene
, vol.31
, pp. 1468-1474
-
-
Jennewein, C.1
Karl, S.2
Baumann, B.3
Micheau, O.4
Debatin, K.M.5
Fulda, S.6
-
45
-
-
68149156979
-
Trimer stabilization, oligomerization, and antibody-mediated cell surface immobilization improve the activity of soluble trimers of CD27L, CD40L, 41BBL, and glucocorticoid-induced TNF receptor ligand
-
doi:10.4049/jimmunol.0802597
-
Wyzgol A, Müller N, Fick A, Munkel S, Grigoleit GU, Pfizenmaier K, et al. Trimer stabilization, oligomerization, and antibody-mediated cell surface immobilization improve the activity of soluble trimers of CD27L, CD40L, 41BBL, and glucocorticoid-induced TNF receptor ligand. J Immunol (2009) 183:1851-61. doi:10.4049/jimmunol.0802597.
-
(2009)
J Immunol
, vol.183
, pp. 1851-1861
-
-
Wyzgol, A.1
Müller, N.2
Fick, A.3
Munkel, S.4
Grigoleit, G.U.5
Pfizenmaier, K.6
|