Retinal pigment epithelium culture; a potential source of retinal stem cells

Journal of Ophthalmic and Vision Research

Volumn 4, Issue 3, 2009, Pages 134-141

  Akrami, Hassan ^a   Soheili, Zahra Soheila ^b   Khalooghi, Keynoush ^b,c   Ahmadieh, Hamid ^d   Rezaie Kanavi, Mojgan ^d   Samiei, Shahram ^e   Davari, Malihe ^b   Ghaderi, Shima ^b   Sanie Jahromi, Fatemeh ^b  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

^c KHARAZMI UNIVERSITY   (Iran)

^d SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e IRANIAN BLOOD TRANSFUSION ORGANIZATION   (Iran)

Author keywords

Retinal pigment epithelium; Stem cells

Indexed keywords

EID: 84897586019     PISSN: 20082010     EISSN: 2008322X     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Lotery A, Trump D. Progress in defining the molecular biology of age related macular degeneration. Hum Genet 2007;122:219-236.
2. Wang AL, Lukas TJ, Yuan M, Neufeld AH. Increased mitochondrial DNA damage and downregulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid. Mol Vis 2008;14:644-651.
3. Lanzetta. New treatments for CNV secondary to AMD: what evidence exists to support a treatment recommendation? Graefe's Arch Clin Exp Ophthalmol 2002;240:885-888.
4. Singh CN, Saperstein DA. Combination treatment with reduced-fluence photodynamic therapy and intravitreal injection of triamcinolone for subfoveal choroidal neovascularization in macular degeneration. Retina 2008;28:789-793.
5. Pieramici DJ, Rabena MD. Anti-VEGF therapy: comparison of current and future agents. Eye 2008;22:1330-1336.
6. Spaide R. New treatments for AMD. Ophthalmology 2006;113:160-161.
7. Binder S, Stanzel B, Krebs I, Glittenberg C. Transplantation of the RPE in AMD. Prog Retin Eye Res 2007;26:516-554.
8. Petrukhin K. New therapeutic targets in atrophic age-related macular degeneration. Expert Opin Ther Targets 2007;11:625-639.
9. Carr AJ, Vugler A, Lawrence J, Chen LL, Ahmado A, Chen FK, et al. Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay. Mol Vis 2009;15:283-295.
10. Hirami Y, Osakada F, Takahashi K, Okita K, Yamanaka S, Ikeda H, et al. Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett 2009 Apr 18 [Epub ahead of print].
11. Sheridan CM, Mason S, Pattwell DM, Kent D, Grierson I, Williams R. Replacement of the RPE monolayer. Eye 2009 Jan 23 [Epub ahead of print].
12. Nadri S, Soleimani M, Kiani J, Atashi A, Izadpanah R. Multipotent mesenchymal stem cells from adult human eye conjunctiva stromal cells. Differentiation 2008;76:223-231.
13. Tropepe V, Coles BLK, Chiasson BJ, Horsford DJ, Elia AJ, McInnes RR, et al. Retinal stem cells in the adult mammalian eye. Science 2000;287:2032-2036.
14. Maclaren RE, Uppal GS, Balaggan KS, Tufail A, Munro PMG, Milliken AB, et al. Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular agerelated macular degeneration. Ophthalmology 2007;114:561-570.
15. Limb GA, Daniels JT. Ocular regeneration by stem cells: present status and future prospects. Br Med Bull 2008;85:47-61.
16. Vugler A, Lawrence J, Walsh J, Carr A, Gias C, Semo M, et al. Embryonic stem cells and retinal repair. Mech Dev 2007;124:807-829.
17. Smukler SR, Runciman SB, Xu S, van der Kooy D. Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences. J Cell Biol 2006;172:79-80.
18. Atmaca-Sonmez P, Li Y, Yamauchi Y, Schanie CL, Ildstad ST, Kaplan HJ, et al. Systemically transferred hematopoietic stem cells home to the subretinal space and express RPE-65 in a mouse model of retinal pigment epithelium damage. Exp Eye Res 2006;83:1295-1302.
19. Lamba DA, Karl ME, Ware CB, Reh TA. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci U S A 2006;103:12769-12774.
20. Fischer A J, Reh TA. Trans-differentiation of pigmented epithelial cells: a source of retinal stem cells. Dev Neurosci 2001;23:268-276.
21. Liang L, Yan RT, Ma W, Zhang H, Wang SZ. Exploring RPE as a source of photoreceptors: differentiation and integration of transdifferentiating cells grafted into embryonic chick eyes. Invest Ophthalmol Vis Sci 2006;47:5066-5074.
22. Kholodenko IV, Buzdin AA, Kholodenko RV, Baibikova JA. Mouse retinal progenitor cell (RPC) cocultivation with retinal pigment epithelial cell culture affects features of RPC differentiation. J Biochem 2006;71:767-774.
23. Mannagh J, Arya DV, Irvine AR. Tissue culture of human retinal pigment epithelium. Invest Ophthalmol Vis Sci 1973;12:52-64.
24. Flood MT, Gouras P, Kjeldbye H. Growth characteristics and ultrastructure of human retinal pigment epithelium in vitro. Invest Ophtalmol Vis Sci 1980;19:1309-1320.
25. Kim SY, Mocanu C, Mcleod DS, Bhutto I A, Merges C, Eid M, et al. Expression of pigment epitheliumderived factor (PEDF) and vascular endothelial growth factor (VEGF) in sickle cell retina and choroid. Exp Eye Res 2003;77:433-445.
26. Chen HF, Kuo HC, Chien CL, Shun CT, Yao YL, Ip PL, et al. Derivation, characterization and differentiation of human embryonic stem cells: comparing serum-containing versus serum-free media and evidence of germ cell differentiation. Hum Reprod 2007;22:567-577.
27. Mannello F, Tonti G A. Concise review: no breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serumfree, serum replacement nonconditioned medium, or Ad hoc formula? All that glitters is not gold! Stem Cells 2007;25:1603-1609.
28. Berger MG, Veyrat-Masson R, Rapatel C, Descamps S, Chassagne J, Boiret-Dupre N. Cell culture medium composition and translational adult bone marrow-derived stem cell research. Stem Cells 2006;24:2888-2890.
29. Sotiropoulou PA, Perez SA, Salagianni M, Baxevanis CN, Papamichail M. Cell culture medium composition and translational adult bone marrowderived stem cell research. Stem Cells 2006;24:1409-1410.
30. Kume T, Taguchi R, Katsuki H, Akao M, Sugimoto H, Kaneko S, et al. Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibit mitochondrial depolarization and caspase-3 activation. Eur J Pharmacol 2006;542:69-76.
31. Bernardo ME, Avanzini MA, Perotti C, Cometa AM, Moretta A, Lenta E, et al. Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for cell therapy approaches: further insight in the search for a fetal calf serum substitute. J Cell Physiol 2007;211:121-130.