Systemically transferred hematopoietic stem cells home to the subretinal space and express RPE-65 in a mouse model of retinal pigment epithelium damage

Experimental Eye Research

Volumn 83, Issue 5, 2006, Pages 1295-1302

  Atmaca Sonmez, Pelin ^a   Li, Yang ^a   Yamauchi, Yasuyuki ^a,c   Schanie, Carrie L ^b   Ildstad, Suzanne T ^b   Kaplan, Henry J ^a   Enzmann, Volker ^a,d  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c TOKYO MEDICAL UNIVERSITY HOSPITAL   (Japan)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

hematopoietic stem cells; homing; RPE degeneration; RPE 65 expression; sodium iodate; stem cells; transplantation

Indexed keywords

ANTIBODY; ATAXIN 1; CD45 ANTIGEN; CELL MARKER; GREEN FLUORESCENT PROTEIN; RETINAL PIGMENT EPITHELIUM 65; SODIUM IODATE; STEM CELL FACTOR; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; BONE MARROW; CELL COUNT; CELL LINEAGE; CELL LOSS; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOCYTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA INJURY;

ANIMALS; APOPTOSIS; CELL LINEAGE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GREEN FLUORESCENT PROTEINS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; IMMUNOHISTOCHEMISTRY; IODATES; LUMINESCENT AGENTS; MALE; MICE; MICE, INBRED C57BL; PIGMENT EPITHELIUM OF EYE; PLURIPOTENT STEM CELLS; RETINAL DEGENERATION;

EID: 33748693311     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2006.07.013     Document Type: Article

References (34)

1. Aliotta J.M., Passero M., Meharg J., Klinger J., Dooner M.S., Pimentel J., and Quesenberry P.J. Stem cells and pulmonary metamorphosis: new concepts in repair and regeneration. J. Cell. Physiol. 204 (2005) 725-741
2. Alvarez-Dolado M., Pardal R., Garcia-Verdugo J.M., Fike J.R., Lee H.O., Pfeffer K., Lois C., Morrison S.J., and Alvarez-Buylla A. Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425 (2003) 968-973
3. Baich A., and Ziegler M. The effect of sodium iodate and melanin on the formation of glyoxylate. Pigment Cell Res. 5 (1992) 394-395
4. Bonner-Weir S., and Weir G.C. New sources of pancreatic beta-cells. Nat. Biotechnol. 23 (2005) 857-861
5. Crane I.J., Wallace C.A., McKillop-Smith S., and Forrester J.V. CXCR4 receptor expression on human retinal pigment epithelial cells from the blood-retina barrier leads to chemokine secretion and migration in response to stromal cell-derived factor 1 alpha. J. Immunol. 165 (2000) 4372-4378
6. De Bari C., Dell'Accio F., Vandenabeele F., Vermeesch J.R., Raymackers J.M., and Luyten F.P. Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane. J. Cell Biol. 160 (2003) 909-918
7. Enzmann V., Row B.R., Yamauchi Y., Kheirandish L., Gozal D., Kaplan H.K., and McCall M.A. Behavioral, electrophysiological and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration. Exp. Eye Res. 82 (2006) 441-448
8. Fugier-Vivier I.J., Rezzoug F., Huang Y., Graul-Layman A.J., Schanie C.L., Xu H., Chilton P.M., and Ildstad S.T. Plasmacytoid precursor dendritic cells facilitate allogeneic hematopoietic stem cell engraftment. J. Exp. Med. 201 (2005) 373-383
9. Goldman S. Stem and progenitor cell-based therapy of the human central nervous system. Nat. Biotechnol. 23 (2005) 862-871
10. Grimes H.L., Schanie C.L., Huang Y., Cramer D., Rezzoug F., Fugier-Vivier I., and Ildstad S.T. Graft facilitating cells are derived from hematopoietic stem cells and functionally require CD3, but are distinct from T lymphocytes. Exp. Hematol. 32 (2004) 946-954
11. Guo X., Wang C., Zhang Y., Xia R., Hu M., Duan C., Zhao Q., Dong L., Lu J., and Qing Song Y. Repair of large articular cartilage defects with implants of autologous mesenchymal stem cells seeded into beta-tricalcium phosphate in a sheep model. Tissue Eng. 10 (2004) 1818-1829
12. Hamel C.P., Tsilou E., Harris E., Pfeffer B.A., Hooks J.J., Detrick B., and Redmond T.M. A developmentally regulated microsomal protein specific for the pigment epithelium of the vertebrate retina. J. Neurosci. Res. 34 (1993) 414-425
13. Haruta M., Sasai Y., Kawasaki H., Amemiya K., Ooto S., Kitada M., Suemori H., Nakatsuji N., Ide C., Honda Y., and Takahashi M. In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells. Invest. Ophthalmol. Vis. Sci. 45 (2004) 1020-1025
14. Hatch H.M., Zheng D., Jorgensen M.L., and Petersen B.E. SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. Cloning Stem Cells 4 (2002) 339-351
15. Hattori K., Heissig B., and Rafii S. The regulation of hematopoietic stem cell and progenitor mobilization by chemokine SDF-1. Leuk. Lymphoma 44 (2003) 575-582
16. Hayasaka S., Noda S., and Setogawa T. Effect of drugs in vitro on lysosomal enzyme activities in bovine retinal pigment epithelial cells. Jpn. J. Ophthalmol. 32 (1988) 316-321
17. Jiang Y., Jahagirdar B.N., Reinhardt R.L., Schwartz R.E., Keene C.D., Ortiz-Gonzalez X.R., Reyes M., Lenvik T., Lund T., Blackstad M., Du J., Aldrich S., Lisberg A., Low W.C., Largaespada D.A., and Verfaillie C.M. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418 (2002) 41-49
18. Kaufman C.L., Colson Y.L., Wren S.M., Watkins S., Simmons R.L., and Ildstad S.T. Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells. Blood 84 (1994) 2436-2446
19. Kicic A., Shen W.Y., Wilson A.S., Constable I.J., Robertson T., and Rakoczy P.E. Differentiation of marrow stromal cells into photoreceptors in the rat eye. J. Neurosci. 23 (2003) 7742-7749
20. Konda B.R., Pararajasegaram G., Wu G.S., Stanforth D., and Rao N.A. Role of retinal pigment epithelium in the development of experimental autoimmune uveitis. Invest. Ophthalmol. Vis. Sci. 35 (1994) 40-47
21. Kucia M., Ratajczak J., Reca R., Janowska-Wieczorek A., and Ratajczak M.Z. Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury. Blood Cells Mol. Dis. 32 (2004) 52-57
22. Kucia M., Ratajczak J., and Ratajczak M.Z. Bone marrow as a source of circulating CXCR4+ tissue-committed stem cells. Biol. Cell 97 (2005) 133-146
23. Laflamme M.A., and Murry C.E. Regenerating the heart. Nat. Biotechnol. 23 (2005) 845-856
24. Lemoli R.M., Bertolini F., Cancedda R., De Luca M., Del Santo A., Ferrari G., Ferrari S., Martino G., Mavilio F., and Tura S. Stem cell plasticity: time for a reappraisal?. Haematologica 90 (2005) 360-381
25. Li X.C., and Strom T.B. A rare find - cells that improve bone marrow transplantation. Nat. Med. 6 (2000) 866-867
26. Li Y., Reca R., Atmaca-Sonmez P., Ratajzcak M.Z., Ildstad S.T., Kaplan H.J., and Enzmann V. Retinal pigment epithelium damage enhances expression of chemoattractants and migration of bone marrow-derived stem cells. Invest. Ophthalmol. Vis. Sci. 47 (2006) 1646-1652
27. Neipp M., Zorina T., Domenick M.A., Exner B.G., and Ildstad S.T. Effect of FLT3 ligand and granulocyte colony-stimulating factor on expansion and mobilization of facilitating cells and hematopoietic stem cells in mice: Kinetics and repopulating potential. Blood 92 (1998) 3177-3188
28. Otani A., Dorrell M.I., Kinder K., Moreno S.K., Nusinowitz S., Banin E., Heckenlively J., and Friedlander M. Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells. J. Clin. Invest. 114 (2004) 765-774
29. Tezel T.H., Kaplan H.J., and Del Priore L.V. Fate of human retinal pigment epithelial cells seeded onto layers of human Bruch's membrane. Invest. Ophthalmol. Vis. Sci. 40 (1999) 467-476
30. Tomita M., Adachi Y., Yamada H., Takahashi K., Kiuchi K., Oyaizu H., Ikebukuro K., Kaneda H., Matsumura M., and Ikehara S. Bone marrow-derived stem cells can differentiate into retinal cells in injured rat retina. Stem Cells 20 (2002) 279-283
31. Uchida N., Aguila H.L., Fleming W.H., Jerabek L., and Weissman I.L. Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.1lo Lin-Sca-1+ hematopoietic stem cells. Blood 83 (1994) 3758-3779
32. Wang X., Ge S., McNamara G., Hao Q.L., Crooks G.M., and Nolta J.A. Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells. Blood 101 (2003) 4201-4208
33. Wollert K.C., Meyer G.P., Lotz J., Ringes-Lichtenberg S., Lippolt P., Breidenbach C., Fichtner S., Korte T., Hornig B., Messinger D., Arseniev L., Hertenstein B., Ganser A., and Drexler H. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomized controlled clinical trial. Lancet 364 (2004) 141-148
34. Zarbin M.A. Current concepts in the pathogenesis of age-related macular degeneration. Arch. Ophthalmol 122 (2004) 598-614