메뉴 건너뛰기




Volumn 34, Issue 4, 2014, Pages 724-734

The pentose phosphate pathway and pyruvate carboxylation after neonatal hypoxic-ischemic brain injury

Author keywords

Astrocytes; Brain development; Brain ischemia; Energy metabolism; Magnetic resonance

Indexed keywords

CARBON 13; GLUCOSE; PYRUVATE DEHYDROGENASE; PYRUVIC ACID;

EID: 84897572413     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.8     Document Type: Article
Times cited : (42)

References (40)
  • 1
    • 79251563456 scopus 로고    scopus 로고
    • Perinatal hypoxic-ischemic encephalopathy
    • Lai MC, Yang SN. Perinatal hypoxic-ischemic encephalopathy. J Biomed Biotechnol 2011; 2011: 609813.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 609813
    • Lai, M.C.1    Yang, S.N.2
  • 2
    • 0035028936 scopus 로고    scopus 로고
    • Early neurodegeneration after hypoxia-ischemia in neonatal rat is necrosis while delayed neuronal death is apoptosis
    • Northington FJ, Ferriero DM, Graham EM, Traystman RJ, Martin LJ. Early neurodegeneration after hypoxia-ischemia in neonatal rat is necrosis while delayed neuronal death is apoptosis. Neurobiol Dis 2001; 8: 207-219.
    • (2001) Neurobiol Dis , vol.8 , pp. 207-219
    • Northington, F.J.1    Ferriero, D.M.2    Graham, E.M.3    Traystman, R.J.4    Martin, L.J.5
  • 3
    • 0014469422 scopus 로고
    • Effect of ischemia on metabolism of the brain of the newborn mouse
    • Thurston JH, McDougal Jr. DB. Effect of ischemia on metabolism of the brain of the newborn mouse. Am J Physiol 1969; 216: 348-352.
    • (1969) Am J Physiol , vol.216 , pp. 348-352
    • Thurston, J.H.1    McDougal Jr., D.B.2
  • 4
    • 0015020675 scopus 로고
    • Ketone-body utilization by adult and suckling rat brain in vivo
    • Hawkins RA, Williamson DH, Krebs HA. Ketone-body utilization by adult and suckling rat brain in vivo. Biochem J 1971; 122: 13-18.
    • (1971) Biochem J , vol.122 , pp. 13-18
    • Hawkins, R.A.1    Williamson, D.H.2    Krebs, H.A.3
  • 5
    • 0028144565 scopus 로고
    • Cerebral glucose and energy utilization during the evolution of hypoxic-ischemic brain damage in the immature rat
    • Vannucci RC, Yager JY, Vannucci SJ. Cerebral glucose and energy utilization during the evolution of hypoxic-ischemic brain damage in the immature rat. J Cereb Blood Flow Metab 1994; 14: 279-288.
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 279-288
    • Vannucci, R.C.1    Yager, J.Y.2    Vannucci, S.J.3
  • 6
    • 84896719920 scopus 로고    scopus 로고
    • Neuronastrocyte interactions, pyruvate carboxylation and the pentose phosphate pathway in the neonatal rat brain
    • doi:10.1007/s11064-013-1014-3 (e-pub ahead of print)
    • Morken TS, Brekke E, Haberg A, Wideroe M, Brubakk AM, Sonnewald U. Neuronastrocyte interactions, pyruvate carboxylation and the pentose phosphate pathway in the neonatal rat brain. Neurochem Res 2013; doi:10.1007/s11064-013- 1014-3 (e-pub ahead of print).
    • (2013) Neurochem Res
    • Morken, T.S.1    Brekke, E.2    Haberg, A.3    Wideroe, M.4    Brubakk, A.M.5    Sonnewald, U.6
  • 7
    • 23244434256 scopus 로고    scopus 로고
    • Perinatal hypoxic-ischemic brain damage: Evolution of an animal model
    • Vannucci RC, Vannucci SJ. Perinatal hypoxic-ischemic brain damage: evolution of an animal model. Dev Neurosci 2005; 27: 81-86.
    • (2005) Dev Neurosci , vol.27 , pp. 81-86
    • Vannucci, R.C.1    Vannucci, S.J.2
  • 8
    • 0029800421 scopus 로고    scopus 로고
    • Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity
    • Ben-Yoseph O, Boxer PA, Ross BD. Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity. Neurochem Res 1996; 21: 1005-1012.
    • (1996) Neurochem Res , vol.21 , pp. 1005-1012
    • Ben-Yoseph, O.1    Boxer, P.A.2    Ross, B.D.3
  • 11
    • 0035071603 scopus 로고    scopus 로고
    • Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates
    • Vento M, Asensi M, Sastre J, Garcia-Sala F, Pallardo FV, Vina J. Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates. Pediatrics 2001; 107: 642-647.
    • (2001) Pediatrics , vol.107 , pp. 642-647
    • Vento, M.1    Asensi, M.2    Sastre, J.3    Garcia-Sala, F.4    Pallardo, F.V.5    Vina, J.6
  • 12
    • 27444445186 scopus 로고    scopus 로고
    • Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury
    • Bartnik BL, Sutton RL, Fukushima M, Harris NG, Hovda DA, Lee SM. Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury. J Neurotrauma 2005; 22: 1052-1065.
    • (2005) J Neurotrauma , vol.22 , pp. 1052-1065
    • Bartnik, B.L.1    Sutton, R.L.2    Fukushima, M.3    Harris, N.G.4    Hovda, D.A.5    Lee, S.M.6
  • 13
    • 0023912479 scopus 로고
    • Hexose monophosphate pathway activity in normal and hypoxic rat brain
    • Domanska-Janik K. Hexose monophosphate pathway activity in normal and hypoxic rat brain. Resuscitation 1988; 16: 79-90.
    • (1988) Resuscitation , vol.16 , pp. 79-90
    • Domanska-Janik, K.1
  • 15
    • 0021988603 scopus 로고
    • Pyruvate carboxylase: An astrocyte- specific enzyme implicated in the replenishment of amino acid neurotransmitter pools
    • Shank RP, Bennett GS, Freytag SO, Campbell GL. Pyruvate carboxylase: an astrocyte- specific enzyme implicated in the replenishment of amino acid neurotransmitter pools. Brain Res 1985; 329: 364-367.
    • (1985) Brain Res , vol.329 , pp. 364-367
    • Shank, R.P.1    Bennett, G.S.2    Freytag, S.O.3    Campbell, G.L.4
  • 16
    • 0029091514 scopus 로고
    • Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: Immunogold evidence from hippocampal slice cultures
    • Laake JH, Slyngstad TA, Haug FM, Ottersen OP. Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice cultures. J Neurochem 1995; 65: 871-881.
    • (1995) J Neurochem , vol.65 , pp. 871-881
    • Laake, J.H.1    Slyngstad, T.A.2    Haug, F.M.3    Ottersen, O.P.4
  • 17
    • 0016191888 scopus 로고
    • Development of mitochondrial pyruvate metabolism in rat brain
    • Wilbur DO, Patel MS. Development of mitochondrial pyruvate metabolism in rat brain. J Neurochem 1974; 22: 709-715.
    • (1974) J Neurochem , vol.22 , pp. 709-715
    • Wilbur, D.O.1    Patel, M.S.2
  • 18
    • 0345055847 scopus 로고    scopus 로고
    • In vivo injection of [1-13C]glucose and [1, 2-13C]acetate combined with ex vivo 13C nuclear magnetic resonance spectroscopy: A novel approach to the study of middle cerebral artery occlusion in the rat
    • Haberg A, Qu H, Haraldseth O, Unsgard G, Sonnewald U. In vivo injection of [1-13C]glucose and [1, 2-13C]acetate combined with ex vivo 13C nuclear magnetic resonance spectroscopy: a novel approach to the study of middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 1998; 18: 1223-1232.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1223-1232
    • Haberg, A.1    Qu, H.2    Haraldseth, O.3    Unsgard, G.4    Sonnewald, U.5
  • 19
    • 33645857684 scopus 로고    scopus 로고
    • Glutamate and GABA metabolism in transient and permanent middle cerebral artery occlusion in rat: Importance of astrocytes for neuronal survival
    • Haberg A, Qu H, Sonnewald U. Glutamate and GABA metabolism in transient and permanent middle cerebral artery occlusion in rat: importance of astrocytes for neuronal survival. Neurochem Int 2006; 48: 531-540.
    • (2006) Neurochem Int , vol.48 , pp. 531-540
    • Haberg, A.1    Qu, H.2    Sonnewald, U.3
  • 20
    • 0019366919 scopus 로고
    • The influence of immaturity on hypoxicischemic brain damage in the rat
    • Rice 3rd JE, Vannucci RC, Brierley JB. The influence of immaturity on hypoxicischemic brain damage in the rat. Ann Neurol 1981; 9: 131-141.
    • (1981) Ann Neurol , vol.9 , pp. 131-141
    • Rice III, J.E.1    Vannucci, R.C.2    Brierley, J.B.3
  • 21
    • 0025349945 scopus 로고
    • Cerebral blood flow and edema in perinatal hypoxic-ischemic brain damage
    • Mujsce DJ, Christensen MA, Vannucci RC. Cerebral blood flow and edema in perinatal hypoxic-ischemic brain damage. Pediatr Res 1990; 27: 450-453.
    • (1990) Pediatr Res , vol.27 , pp. 450-453
    • Mujsce, D.J.1    Christensen, M.A.2    Vannucci, R.C.3
  • 22
    • 0036949526 scopus 로고    scopus 로고
    • Hypoxic preconditioning increases brain glycogen and delays energy depletion from hypoxia-ischemia in the immature rat
    • Brucklacher RM, Vannucci RC, Vannucci SJ. Hypoxic preconditioning increases brain glycogen and delays energy depletion from hypoxia-ischemia in the immature rat. Dev Neurosci 2002; 24: 411-417.
    • (2002) Dev Neurosci , vol.24 , pp. 411-417
    • Brucklacher, R.M.1    Vannucci, R.C.2    Vannucci, S.J.3
  • 23
    • 0025944058 scopus 로고
    • Cerebral oxidative metabolism and redox state during hypoxia-ischemia and early recovery in immature rats
    • Yager JY, Brucklacher RM, Vannucci RC. Cerebral oxidative metabolism and redox state during hypoxia-ischemia and early recovery in immature rats. Am J Physiol 1991; 26: H1102-H1108.
    • (1991) Am J Physiol , vol.26
    • Yager, J.Y.1    Brucklacher, R.M.2    Vannucci, R.C.3
  • 24
    • 0029067088 scopus 로고
    • N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia
    • Folbergrova J, Zhao Q, Katsura K, Siesjo BK. N-tert-butyl-alpha- phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia. Proc Natl Acad Sci USA 1995; 92: 5057-5061.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5057-5061
    • Folbergrova, J.1    Zhao, Q.2    Katsura, K.3    Siesjo, B.K.4
  • 25
    • 0024376664 scopus 로고
    • Lactate, 3-hydroxybutyrate, and glucose as substrates for the early postnatal rat brain
    • Dombrowski Jr. GJ, Swiatek KR, Chao KL. Lactate, 3-hydroxybutyrate, and glucose as substrates for the early postnatal rat brain. Neurochem Res 1989; 14: 667-675.
    • (1989) Neurochem Res , vol.14 , pp. 667-675
    • Dombrowski Jr., G.J.1    Swiatek, K.R.2    Chao, K.L.3
  • 26
    • 0142084655 scopus 로고    scopus 로고
    • Developmental switch in brain nutrient transporter expression in the rat
    • Vannucci SJ, Simpson IA. Developmental switch in brain nutrient transporter expression in the rat. Am J Physiol Endocrinol Metab 2003; 285: E1127-E1134.
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Vannucci, S.J.1    Simpson, I.A.2
  • 27
    • 0026563804 scopus 로고
    • Cerebral energy metabolism during hypoxia-ischemia and early recovery in immature rats
    • Yager JY, Brucklacher RM, Vannucci RC. Cerebral energy metabolism during hypoxia-ischemia and early recovery in immature rats. Am J Physiol 1992; 262: H672-H677.
    • (1992) Am J Physiol , vol.262
    • Yager, J.Y.1    Brucklacher, R.M.2    Vannucci, R.C.3
  • 28
    • 0031661220 scopus 로고    scopus 로고
    • Copper/ zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia
    • Fullerton HJ, Ditelberg JS, Chen SF, Sarco DP, Chan PH, Epstein CJ et al. Copper/ zinc superoxide dismutase transgenic brain accumulates hydrogen peroxide after perinatal hypoxia ischemia. Ann Neurol 1998; 44: 357-364.
    • (1998) Ann Neurol , vol.44 , pp. 357-364
    • Fullerton, H.J.1    Ditelberg, J.S.2    Chen, S.F.3    Sarco, D.P.4    Chan, P.H.5    Epstein, C.J.6
  • 30
    • 0034731337 scopus 로고    scopus 로고
    • Alterations in glutathione and amino acid concentrations after hypoxia-ischemia in the immature rat brain
    • Wallin C, Puka-Sundvall M, Hagberg H, Weber SG, Sandberg M. Alterations in glutathione and amino acid concentrations after hypoxia-ischemia in the immature rat brain. Brain Res Dev Brain Res 2000; 125: 51-60.
    • (2000) Brain Res Dev Brain Res , vol.125 , pp. 51-60
    • Wallin, C.1    Puka-Sundvall, M.2    Hagberg, H.3    Weber, S.G.4    Sandberg, M.5
  • 31
    • 67349249403 scopus 로고    scopus 로고
    • The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
    • Herrero-Mendez A, Almeida A, Fernandez E, Maestre C, Moncada S, Bolanos JP. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1. Nat Cell Biol 2009; 11: 747-752.
    • (2009) Nat Cell Biol , vol.11 , pp. 747-752
    • Herrero-Mendez, A.1    Almeida, A.2    Fernandez, E.3    Maestre, C.4    Moncada, S.5    Bolanos, J.P.6
  • 32
    • 84866079656 scopus 로고    scopus 로고
    • Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration
    • Rodriguez-Rodriguez P, Fernandez E, Almeida A, Bolanos JP. Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration. Cell Death Differ 2012; 19: 1582-1589.
    • (2012) Cell Death Differ , vol.19 , pp. 1582-1589
    • Rodriguez-Rodriguez, P.1    Fernandez, E.2    Almeida, A.3    Bolanos, J.P.4
  • 33
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • Norenberg MD, Martinez-Hernandez A. Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res 1979; 161: 303-310.
    • (1979) Brain Res , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 35
    • 0031044515 scopus 로고    scopus 로고
    • Brain injury after hypoxia-ischemia in newborn rats: Relationship to extracellular levels of excitatory amino acids and cysteine
    • Puka-Sundvall M, Sandberg M, Hagberg H. Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine. Brain Res 1997; 750: 325-328.
    • (1997) Brain Res , vol.750 , pp. 325-328
    • Puka-Sundvall, M.1    Sandberg, M.2    Hagberg, H.3
  • 37
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt NC. Glutamate uptake. Prog Neurobiol 2001; 65: 1-105.
    • (2001) Prog Neurobiol , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 38
    • 84876191209 scopus 로고    scopus 로고
    • Hypoxia-ischemia alters nucleotide and nucleoside catabolism and Na+, K+-ATPase activity in the cerebral cortex of newborn rats
    • Pimentel VC, Zanini D, Cardoso AM, Schmatz R, Bagatini MD, Gutierres JM et al. Hypoxia-ischemia alters nucleotide and nucleoside catabolism and Na+, K+-ATPase activity in the cerebral cortex of newborn rats. Neurochem Res 2013; 38: 886-894.
    • (2013) Neurochem Res , vol.38 , pp. 886-894
    • Pimentel, V.C.1    Zanini, D.2    Cardoso, A.M.3    Schmatz, R.4    Bagatini, M.D.5    Gutierres, J.M.6
  • 39
    • 0035018620 scopus 로고    scopus 로고
    • Maturational aspects of epilepsy mechanisms and consequences for the immature brain
    • Sanchez RM, Jensen FE. Maturational aspects of epilepsy mechanisms and consequences for the immature brain. Epilepsia 2001; 42: 577-585.
    • (2001) Epilepsia , vol.42 , pp. 577-585
    • Sanchez, R.M.1    Jensen, F.E.2
  • 40
    • 0036719162 scopus 로고    scopus 로고
    • Excitatory actions of GABA during development: The nature of the nurture
    • Ben-Ari Y. Excitatory actions of GABA during development: the nature of the nurture. Nat Rev Neurosci 2002; 3: 728-739.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 728-739
    • Ben-Ari, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.