메뉴 건너뛰기




Volumn 18, Issue 11, 1998, Pages 1223-1232

In vivo injection of [1-13C]glucose and [1,2-13C]acetate combined with ex vivo 13C nuclear magnetic resonance spectroscopy: A novel approach to the study of middle cerebral artery occlusion in the rat

Author keywords

13C nuclear magnetic resonance spectroscopy; Aminobutyric acid; Glutamate; Glutamine; Middle cerebral artery occlusion; Neuronal astrocytic interaction

Indexed keywords

4 AMINOBUTYRIC ACID; ACETIC ACID; CARBON 13; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; PYRUVATE CARBOXYLASE; PYRUVATE DEHYDROGENASE; TRICARBOXYLIC ACID;

EID: 0345055847     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199811000-00008     Document Type: Article
Times cited : (68)

References (35)
  • 1
    • 0025181507 scopus 로고
    • 13C NMR spectroscopy: A technique for investigating metabolic compartmentation in the brain
    • 13C NMR spectroscopy: a technique for investigating metabolic compartmentation in the brain. Biochem J 266:133-139
    • (1990) Biochem J , vol.266 , pp. 133-139
    • Badar-Goffer, R.S.1    Bachelard, H.S.2    Morris, P.G.3
  • 2
    • 0029993974 scopus 로고    scopus 로고
    • Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke
    • Castillo J, Dávalos A, Naveiro J, Noya M (1996) Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke. Stroke 27:1060-1065
    • (1996) Stroke , vol.27 , pp. 1060-1065
    • Castillo, J.1    Dávalos, A.2    Naveiro, J.3    Noya, M.4
  • 4
    • 0023153702 scopus 로고
    • Regional cerebral glucose utilization during hyperglycemia
    • Duckrow RB, Bryan RM Jr (1987) Regional cerebral glucose utilization during hyperglycemia. J Neurochem 48:989-993
    • (1987) J Neurochem , vol.48 , pp. 989-993
    • Duckrow, R.B.1    Bryan R.M., Jr.2
  • 5
    • 0023543626 scopus 로고
    • The neurotransmitter amino acid transport systems: A fresh outlook on an old problem
    • Erecinska M (1987) The neurotransmitter amino acid transport systems: a fresh outlook on an old problem. Biochem Pharmacol 36:3547-3555
    • (1987) Biochem Pharmacol , vol.36 , pp. 3547-3555
    • Erecinska, M.1
  • 6
    • 0021266528 scopus 로고
    • Neurotransmitter amino acids in the CNS. I. Regional changes in amino acid levels in rat brain during ischemia and reperfusion
    • Erecinska M, Nelson D, Wilson DF, Silver IA (1984) Neurotransmitter amino acids in the CNS. I. Regional changes in amino acid levels in rat brain during ischemia and reperfusion. Brain Res 304:9-22
    • (1984) Brain Res , vol.304 , pp. 9-22
    • Erecinska, M.1    Nelson, D.2    Wilson, D.F.3    Silver, I.A.4
  • 7
    • 0029067088 scopus 로고
    • N-Tert-butyl-α-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia
    • Folbergrová J, Zhao Q, Katsura K-I, Siesjö BK (1995) N-Tert-butyl-α-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia. Proc Natl Acad Sci USA 92: 5057-5061
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5057-5061
    • Folbergrová, J.1    Zhao, Q.2    Katsura, K.-I.3    Siesjö, B.K.4
  • 8
    • 0017715649 scopus 로고
    • Cellular events during partial cerebral ischemia. I. Electron microscopy of feline cerebral cortex after middle-cerebral-artery occlusion
    • Garcia JH, Kalimo H, Kamijyo Y, Trump BF (1977) Cellular events during partial cerebral ischemia. I. Electron microscopy of feline cerebral cortex after middle-cerebral-artery occlusion. Virchows Arch B Cell Pathol 25:191-206
    • (1977) Virchows Arch B Cell Pathol , vol.25 , pp. 191-206
    • Garcia, J.H.1    Kalimo, H.2    Kamijyo, Y.3    Trump, B.F.4
  • 9
    • 0026503709 scopus 로고
    • Relative sparing of GAB-Aergic interneurons in the striatum of gerbils with ischemia induced lesions
    • Gonzales C, Lin RC, Chesselet MF (1992) Relative sparing of GAB-Aergic interneurons in the striatum of gerbils with ischemia induced lesions. Neurosci Lett 135:53-58
    • (1992) Neurosci Lett , vol.135 , pp. 53-58
    • Gonzales, C.1    Lin, R.C.2    Chesselet, M.F.3
  • 11
    • 0030612955 scopus 로고    scopus 로고
    • Trafficking of amino acids between neurons and glia in vivo: Effects of inhibition of glial metabolism by fluoroacetate
    • Hassel B, Bachelard H, Fonnum F, Sonnewald U (1997) Trafficking of amino acids between neurons and glia in vivo: effects of inhibition of glial metabolism by fluoroacetate. J Cereb Blood Flow Metab 16:1230-1238
    • (1997) J Cereb Blood Flow Metab , vol.16 , pp. 1230-1238
    • Hassel, B.1    Bachelard, H.2    Fonnum, F.3    Sonnewald, U.4
  • 12
    • 0018670663 scopus 로고
    • Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters
    • Hertz L (1979) Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters. Prog Neurobiol 13:277-323
    • (1979) Prog Neurobiol , vol.13 , pp. 277-323
    • Hertz, L.1
  • 16
    • 0029880586 scopus 로고
    • The effect of depressed glial function in the rat brain in situ on ion homeostasis, synaptic transmission, and neuronal survival
    • Largo C, Cuevas P, Somjen GG, del Río RM, Herreras O (1995) The effect of depressed glial function in the rat brain in situ on ion homeostasis, synaptic transmission, and neuronal survival. J Neurosci 16:1219-1229
    • (1995) J Neurosci , vol.16 , pp. 1219-1229
    • Largo, C.1    Cuevas, P.2    Somjen, G.G.3    Del Río, R.M.4    Herreras, O.5
  • 17
    • 0030061356 scopus 로고    scopus 로고
    • Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes
    • McKenna MC, Sonnewald U, Huang X, Stevenson J, Zielke HR (1996) Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes. J Neurochem 66:386-393
    • (1996) J Neurochem , vol.66 , pp. 386-393
    • McKenna, M.C.1    Sonnewald, U.2    Huang, X.3    Stevenson, J.4    Zielke, H.R.5
  • 19
    • 0023837596 scopus 로고
    • Autoradiographic determination of cerebral glucose content, blood flow, and glucose utilization in focal ischemia in the rat brain: Influence of the plasma glucose concentration
    • Nedergaard M, Jakobsen J, Diemer NH (1988) Autoradiographic determination of cerebral glucose content, blood flow, and glucose utilization in focal ischemia in the rat brain: influence of the plasma glucose concentration. J Cereb Blood Flow Metab 8:100-108
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 100-108
    • Nedergaard, M.1    Jakobsen, J.2    Diemer, N.H.3
  • 20
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • Norenberg MD, Martinez-Hernandez A (1979) Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res 161:303-310
    • (1979) Brain Res , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 21
    • 0021020420 scopus 로고
    • Brain metabolism: A perspective from the blood-brain barrier
    • Pardridge WM (1983) Brain metabolism: a perspective from the blood-brain barrier. Physiol Rev 63:1481-1535
    • (1983) Physiol Rev , vol.63 , pp. 1481-1535
    • Pardridge, W.M.1
  • 22
    • 0016137008 scopus 로고
    • 2-fixing enzymes in the metabolism of rat brain
    • 2-fixing enzymes in the metabolism of rat brain. J Neurochem 22:717-724
    • (1974) J Neurochem , vol.22 , pp. 717-724
    • Patel, M.S.1
  • 23
    • 0026598727 scopus 로고
    • Brain glutamine synthetase increases following cerebral ischemia in the rat
    • Petito CK, Chung MC, Verkhovsky LM, Cooper AJ (1992) Brain glutamine synthetase increases following cerebral ischemia in the rat. Brain Res 569:275-280
    • (1992) Brain Res , vol.569 , pp. 275-280
    • Petito, C.K.1    Chung, M.C.2    Verkhovsky, L.M.3    Cooper, A.J.4
  • 24
    • 0021988603 scopus 로고
    • Pyruvate carboxylase: An astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools
    • Shank RP, Bennett GS, Freytag SO, Campell GL (1985) Pyruvate carboxylase: an astrocyte-specific enzyme implicated in the replenishment of amino acid neurotransmitter pools. Brain Res 329:364-367
    • (1985) Brain Res , vol.329 , pp. 364-367
    • Shank, R.P.1    Bennett, G.S.2    Freytag, S.O.3    Campell, G.L.4
  • 26
  • 29
    • 0028243279 scopus 로고
    • NMR spectroscopic study of cell cultures of astrocytes and neurons exposed to hypoxia: Compartmentation of astrocyte metabolism
    • Sonnewald U, Müller TB, Westergaard N, Unsgård G, Petersen SB, Schousboe A (1994) NMR spectroscopic study of cell cultures of astrocytes and neurons exposed to hypoxia: compartmentation of astrocyte metabolism. Neurochem Int 24:473-483
    • (1994) Neurochem Int , vol.24 , pp. 473-483
    • Sonnewald, U.1    Müller, T.B.2    Westergaard, N.3    Unsgård, G.4    Petersen, S.B.5    Schousboe, A.6
  • 30
    • 0025958468 scopus 로고
    • Glutamine synthetase in oligodendrocytes and astrocytes: New biochemical and immunocytochemical evidence
    • Tansey FA, Farooq M, Cammer W (1991) Glutamine synthetase in oligodendrocytes and astrocytes: new biochemical and immunocytochemical evidence. J Neurochem 56:266-272
    • (1991) J Neurochem , vol.56 , pp. 266-272
    • Tansey, F.A.1    Farooq, M.2    Cammer, W.3
  • 32
    • 0025761431 scopus 로고
    • Cellular and subcellular redistribution of glutamate-, glutamine- and taurine-like immunoreactivities during forebrain ischemia: A semiquantitative electron microscopic study in rat hippocampus
    • Torp R, Andiné P, Hagberg H, Karagülle T, Blackstad TW, Ottersen OP (1991) Cellular and subcellular redistribution of glutamate-, glutamine- and taurine-like immunoreactivities during forebrain ischemia: a semiquantitative electron microscopic study in rat hippocampus. Neuroscience 41:443-447
    • (1991) Neuroscience , vol.41 , pp. 443-447
    • Torp, R.1    Andiné, P.2    Hagberg, H.3    Karagülle, T.4    Blackstad, T.W.5    Ottersen, O.P.6
  • 33
    • 0026633564 scopus 로고
    • Specific expression of N-acetylaspartate in neurons, oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro
    • Urenjak J, Williams SR, Gadian DG, Noblel M (1992) Specific expression of N-acetylaspartate in neurons, oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro. J Neurochem 59:55-61
    • (1992) J Neurochem , vol.59 , pp. 55-61
    • Urenjak, J.1    Williams, S.R.2    Gadian, D.G.3    Noblel, M.4
  • 34
    • 0000765337 scopus 로고
    • A model of compartmentation in the mouse brain based on glucose and acetate metabolism
    • Balazs R and Cremer JE, eds, London, Maximilian Press
    • Van den Berg CJ (1973) A model of compartmentation in the mouse brain based on glucose and acetate metabolism. In: Metabolic Compartmentation in the Brain (Balazs R and Cremer JE, eds), London, Maximilian Press, pp 137-166
    • (1973) Metabolic Compartmentation in the Brain , pp. 137-166
    • Van Den Berg, C.J.1
  • 35


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.