SIRT1 inhibition by sirtinol aggravates brain edema after experimental subarachnoid hemorrhage

Journal of Neuroscience Research

Volumn 92, Issue 6, 2014, Pages 714-722

  Zhou, Xiao Ming ^a   Zhang, Xin ^a,b   Zhang, Xiang Sheng ^a   Zhuang, Zong ^b   Li, Wei ^b   Sun, Qing ^b   Li, Tao ^b   Wang, Chun Xi ^b   Zhu, Lin ^b   Shi, Ji Xin ^b   Zhou, Meng Liang ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Cerebral microvasculature; Early brain injury; Edema; MMP 9; P53; SIRT1; Subarachnoid hemorrhage

Indexed keywords

CASPASE 3; GELATINASE B; PROTEIN P53; SIRTINOL; SIRTUIN 1; BENZAMIDE DERIVATIVE; NAPHTHOL DERIVATIVE; SIRT1 PROTEIN, RAT;

ACETYLATION; ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN FUNCTION; BRAIN LEVEL; BRAIN WATER; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTAL SUBARACHNOID HEMORRHAGE; IMMUNOHISTOCHEMISTRY; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; SUBARACHNOID HEMORRHAGE; ANIMAL; CAPILLARY PERMEABILITY; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; METABOLISM;

ANIMALS; APOPTOSIS; BENZAMIDES; BLOOD-BRAIN BARRIER; BRAIN EDEMA; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; MALE; NAPHTHOLS; RATS; RATS, SPRAGUE-DAWLEY; SIRTUIN 1; SUBARACHNOID HEMORRHAGE;

EID: 84897570385     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23359     Document Type: Article

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