Plasmid transferability of KPC into a virulent K2 serotype Klebsiella pneumoniae

BMC Infectious Diseases

Volumn 14, Issue 1, 2014, Pages

  Siu, Leung Kei K ^a,b   Huang, David B ^c   Chiang, Tom ^c,d  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Klebsiella pneumoniae; Plasmid mediated resistance; Virulence

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZTREONAM; CARBAPENEM; CEFAZOLIN; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; DORIPENEM; ERTAPENEM; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; TIGECYCLINE; ANTIINFECTIVE AGENT; BETA LACTAMASE; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CONJUGATION; CONTROLLED STUDY; KLEBSIELLA PNEUMONIAE; LETHALITY; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PLASMID; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; GENETICS; KLEBSIELLA INFECTION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; VIRULENCE;

ANIMALS; ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CONJUGATION, GENETIC; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; PLASMIDS; VIRULENCE; VIRULENCE FACTORS;

EID: 84897551881     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-14-176     Document Type: Article

References (23)

1. Cheng DL, Liu YC, Yen MY, Liu CY, Wang RS. Septic metastatic lesions of pyogenic liver abscess. Their association with Klebsiella pneumoniae bacteremia in diabetic patients. Arch Intern Med 1991, 151(8):1557-1559. 10.1001/archinte.1991.00400080059010, 1872659.
2. Liu YC, Cheng DL, Lin CL. Klebsiella pneumoniae liver abscess associated with septic endophthalmitis. Arch Intern Med 1986, 146(10):1913-1916. 10.1001/archinte.1986.00360220057011, 3532983.
3. Wang JH, Liu YC, Lee SS, Yen MY, Chen YS, Wann SR, Lin HH. Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clin Infect Dis 1998, 26(6):1434-1438. 10.1086/516369, 9636876.
4. Rivero A, Gomez E, Alland D, Huang DB, Chiang T. K2 serotype Klebsiella pneumoniae causing a liver abscess associated with infective endocarditis. J Clin Microbiol 2010, 48(2):639-641. 10.1128/JCM.01779-09, 2815605, 20007381.
5. Ambrozic J, Ostroversnik A, Starcic M, Kuhar I, Grabnar M, Zgur-Bertok D. Escherichia coli CoIV plasmid pRK100: genetic organization, stability and conjugal transfer. Microbiology 1998, 144(Pt 2):343-352.
6. D'Agata EM, Gerrits MM, Tang YW, Samore M, Kusters JG. Comparison of pulsed-field gel electrophoresis and amplified fragment-length polymorphism for epidemiological investigations of common nosocomial pathogens. Infect Control Hosp Epidemiol 2001, 22(9):550-554. 10.1086/501950, 11732783.
7. McDougal LK, Steward CD, Killgore GE, Chaitram JM, McAllister SK, Tenover FC. Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database. J Clin Microbiol 2003, 41(11):5113-5120. 10.1128/JCM.41.11.5113-5120.2003, 262524, 14605147.
8. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995, 33(9):2233-2239. 228385, 7494007.
9. Bradford PA, Bratu S, Urban C, Visalli M, Mariano N, Landman D, Rahal JJ, Brooks S, Cebular S, Quale J. Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 beta-lactamases in New York City. Clin Infect Dis 2004, 39(1):55-60. 10.1086/421495, 15206053.
10. Sanger F, Air GM, Barrell BG, Brown NL, Coulson AR, Fiddes CA, Hutchison CA, Slocombe PM, Smith M. Nucleotide sequence of bacteriophage phi X174 DNA. Nature 1977, 265(5596):687-695. 10.1038/265687a0, 870828.
11. Tsai YK, Fung CP, Lin JC, Chen JH, Chang FY, Chen TL, Siu LK. Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence. Antimicrob Agents Chemother 2011, 55(4):1485-1493. 10.1128/AAC.01275-10, 3067157, 21282452.
12. Siu LK, Ho PL, Yuen KY, Wong SS, Chau PY. Transferable hyperproduction of TEM-1 beta-lactamase in Shigella flexneri due to a point mutation in the pribnow box. Antimicrob Agents Chemother 1997, 41(2):468-470. 163732, 9021210.
13. Wang M, Tran JH, Jacoby GA, Zhang Y, Wang F, Hooper DC. Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China. Antimicrob Agents Chemother 2003, 47(7):2242-2248. 10.1128/AAC.47.7.2242-2248.2003, 161834, 12821475.
14. Yeh KM, Lin JC, Yin FY, Fung CP, Hung HC, Siu LK, Chang FY. Revisiting the importance of virulence determinant magA and its surrounding genes in Klebsiella pneumoniae causing pyogenic liver abscesses: exact role in serotype K1 capsule formation. J Infect Dis 2010, 201(8):1259-1267. 10.1086/606010, 19785524.
15. Turton JF, Baklan H, Siu LK, Kaufmann ME, Pitt TL. Evaluation of a multiplex PCR for detection of serotypes K1, K2 and K5 in Klebsiella sp. and comparison of isolates within these serotypes. FEMS Microbiol Lett 2008, 284(2):247-252. 10.1111/j.1574-6968.2008.01208.x, 18507682.
16. Chiu SK, Wu TL, Chuang YC, Lin JC, Fung CP, Lu PL, Wang JT, Wang LS, Siu LK, Yeh KM. National surveillance study on carbapenem non-susceptible Klebsiella pneumoniae in Taiwan: the emergence and rapid dissemination of KPC-2 carbapenemase. PLoS One 2013, 8(7):e69428. 10.1371/journal.pone.0069428, 3722148, 23894478.
17. Siu LK, Fung CP, Chang FY, Lee N, Yeh KM, Koh TH, Ip M. Molecular typing and virulence analysis of serotype K1 Klebsiella pneumoniae strains isolated from liver abscess patients and stool samples from noninfectious subjects in Hong Kong, Singapore, and Taiwan. J Clin Microbiol 2011, 49(11):3761-3765. 10.1128/JCM.00977-11, 3209116, 21900521.
18. Turton JF, Englender H, Gabriel SN, Turton SE, Kaufmann ME, Pitt TL. Genetically similar isolates of Klebsiella pneumoniae serotype K1 causing liver abscesses in three continents. J Med Microbiol 2007, 56(Pt 5):593-597.
19. Lin JC, Chang FY, Fung CP, Xu JZ, Cheng HP, Wang JJ, Huang LY, Siu LK. High prevalence of phagocytic-resistant capsular serotypes of Klebsiella pneumoniae in liver abscess. Microbes Infect 2004, 6(13):1191-1198. 10.1016/j.micinf.2004.06.003, 15488738.
20. Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, Alberti S, Bush K, Tenover FC. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother 2001, 45(4):1151-1161. 10.1128/AAC.45.4.1151-1161.2001, 90438, 11257029.
21. Pournaras S, Zarkotou O, Poulou A, Kristo I, Vrioni G, Themeli-Digalaki K, Tsakris A. A combined disk test for direct differentiation of carbapenemase-producing enterobacteriaceae in surveillance rectal swabs. J Clin Microbiol 2013, 51(9):2986-2990. 10.1128/JCM.00901-13, 3754636, 23843486.
22. Siu LK, Yeh KM, Lin JC, Fung CP, Chang FY. Klebsiella pneumoniae liver abscess: a new invasive syndrome. Lancet Infect Dis 2012, 12(11):881-887. 10.1016/S1473-3099(12)70205-0, 23099082.
23. Li W, Sun G, Yu Y, Li N, Chen M, Jin R, Jiao Y, Wu H. Increasing occurrence of antimicrobial-resistant hypervirulent (hypermucoviscous) Klebsiella pneumoniae isolates in China. Clin Infect Dis 2014, 58(2):225-232. 10.1093/cid/cit675, 24099919.