ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 13, 2014, Pages 5024-5029

  Quazi, Faraz ^a   Molday, Robert S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

ABC transporters; Photoreceptor degeneration; Retinal pigment epithelial cells; Retinoids; Stargardt disease

Indexed keywords

11 CIS RETINAL; ABC TRANSPORTER; ABCA4 PROTEIN; DOCOSAHEXAENOIC ACID; PHOSPHATIDYLETHANOLAMINE; RETINOL; RETINOL DEHYDROGENASE; SCHIFF BASE; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; CONJUGATE; ISOMERIZATION; NONHUMAN; PHOTORECEPTOR CELL; PHOTORECEPTOR MEMBRANE; PRIORITY JOURNAL; STARGARDT DISEASE; TRANS ISOMER;

ABC TRANSPORTERS; PHOTORECEPTOR DEGENERATION; RETINAL PIGMENT EPITHELIAL CELLS; RETINOIDS; STARGARDT DISEASE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CATTLE; CYTOPROTECTION; ISOMERISM; MICE; MODELS, BIOLOGICAL; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; PHOTORECEPTOR CELLS, VERTEBRATE; PROTEOLIPIDS; RETINOIDS; ROD CELL OUTER SEGMENT; SUS SCROFA; VITAMIN A;

EID: 84897542644     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1400780111     Document Type: Article

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