Acute lymphoblastic leukemia with low hypodiploid/near triploid karyotype is a specific clinical entity and exhibits a very high TP53 mutation frequency of 93%

Genes Chromosomes and Cancer

Volumn 53, Issue 6, 2014, Pages 524-536

  Mühlbacher, Verena ^a   Zenger, Melanie ^a   Schnittger, Susanne ^a   Weissmann, Sandra ^a   Kunze, Franziska ^a   Kohlmann, Alexander ^a   Bellos, Frauke ^a   Kern, Wolfgang ^a   Haferlach, Torsten ^a   Haferlach, Claudia ^a  

^a MLL MUNICH LEUKEMIA LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; FBXW7 PROTEIN; IKZFI PROTEIN; K RAS PROTEIN; NOTCH1 RECEPTOR; PROTEIN; PROTEIN P53; TRANSCRIPTION FACTOR ETV6; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CHROMOSOME 13; CHROMOSOME 15; CHROMOSOME 16; CHROMOSOME 17; CHROMOSOME 3; CHROMOSOME 7; CHROMOSOME BANDING PATTERN; CHROMOSOME LOSS; CHROMOSOME MUTATION; CHROMOSOME NUMBER; CLINICAL FEATURE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DIPLOIDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HYPODIPLOID KARYOTYPE; IMMUNOPHENOTYPING; INTERPHASE; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MUTATION RATE; MUTATIONAL ANALYSIS; OVERALL SURVIVAL; PRIORITY JOURNAL; SEX CHROMOSOME; TETRAPLOIDY; TRIPLOIDY; VERY ELDERLY; WORLD HEALTH ORGANIZATION;

ABNORMAL KARYOTYPE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; MALE; MIDDLE AGED; MUTATION RATE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TRIPLOIDY; TUMOR SUPPRESSOR PROTEIN P53; YOUNG ADULT;

EID: 84897504549     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.22163     Document Type: Article

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