메뉴 건너뛰기




Volumn 33, Issue 12, 2013, Pages 1308-1321

Reducing the risk of obesity: Defining the role of weight loss drugs

Author keywords

bariatric surgery; diet; exercise; obesity; weight loss drugs

Indexed keywords

AMFEBUTAMONE PLUS NALTREXONE; AMFEPRAMONE; ANTIOBESITY AGENT; BENZPHETAMINE; DEXFENFLURAMINE; FENFLURAMINE; GLUCOSE; INSULIN; LORCASERIN; PHENDIMETRAZINE; PHENTERMINE; PHENTERMINE PLUS TOPIRAMATE; PLACEBO; RIMONABANT; SIBUTRAMINE; TETRAHYDROLIPSTATIN;

EID: 84897500490     PISSN: 02770008     EISSN: 18759114     Source Type: Journal    
DOI: 10.1002/phar.1277     Document Type: Review
Times cited : (17)

References (77)
  • 1
    • 4444228888 scopus 로고    scopus 로고
    • World Health Organization Accessed October 18
    • World Health Organization. Obesity and overweight. Available from http://www.who.int/mediacnetre/factsheets/fs311/index.html. Accessed October 18, 2012.
    • (2012) Obesity and Overweight
  • 2
    • 84856487711 scopus 로고    scopus 로고
    • Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
    • Flegal KM, Carroll MD, Kit BK, Ogden CL,. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 2012; 307 (5): 491-7.
    • (2012) JAMA , vol.307 , Issue.5 , pp. 491-497
    • Flegal, K.M.1    Carroll, M.D.2    Kit, B.K.3    Ogden, C.L.4
  • 3
    • 84856433589 scopus 로고    scopus 로고
    • Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010
    • Ogden CL, Carroll MD, Kit BK, Flegal KM,. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012; 307 (5): 483-90.
    • (2012) JAMA , vol.307 , Issue.5 , pp. 483-490
    • Ogden, C.L.1    Carroll, M.D.2    Kit, B.K.3    Flegal, K.M.4
  • 4
    • 33748931457 scopus 로고    scopus 로고
    • Central nervous system control of food intake and body weight
    • Morton G, Cummings D, Baskin D, Barsh G, Schwartz M,. Central nervous system control of food intake and body weight. Nature 2006; 443 (7109): 289-95.
    • (2006) Nature , vol.443 , Issue.7109 , pp. 289-295
    • Morton, G.1    Cummings, D.2    Baskin, D.3    Barsh, G.4    Schwartz, M.5
  • 5
    • 77954738662 scopus 로고    scopus 로고
    • Genetic studies of common types of obesity: A critique of the current use of phenotypes
    • Müller M, Bosy-Westphal A, Krawczak M,. Genetic studies of common types of obesity: a critique of the current use of phenotypes. Obes Rev 2010; 11 (8): 612-8.
    • (2010) Obes Rev , vol.11 , Issue.8 , pp. 612-618
    • Müller, M.1    Bosy-Westphal, A.2    Krawczak, M.3
  • 6
    • 56849126500 scopus 로고    scopus 로고
    • Epidemiological study designs to investigate gene-behavior interactions in the context of human obesity
    • Wareham NJ, Young EH, Loos RJF,. Epidemiological study designs to investigate gene-behavior interactions in the context of human obesity. Obesity 2012; 16 (S3): S66-71.
    • (2012) Obesity , vol.16 , Issue.3
    • Wareham, N.J.1    Young, E.H.2    Loos, R.J.F.3
  • 7
    • 74249088988 scopus 로고    scopus 로고
    • The genetic and environmental influences on childhood obesity: A systematic review of twin and adoption studies
    • Silventoinen K, Rokholm B, Kaprio J, Sørensen T,. The genetic and environmental influences on childhood obesity: a systematic review of twin and adoption studies. Int J Obes 2009; 34 (1): 29-40.
    • (2009) Int J Obes , vol.34 , Issue.1 , pp. 29-40
    • Silventoinen, K.1    Rokholm, B.2    Kaprio, J.3    Sørensen, T.4
  • 8
    • 77649217019 scopus 로고    scopus 로고
    • Overweight, obesity, and depression: A systematic review and meta-analysis of longitudinal studies
    • Luppino FS, De Wit LM, Bouvy PF, et al. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry 2010; 67 (3): 220-9.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.3 , pp. 220-229
    • Luppino, F.S.1    De Wit, L.M.2    Bouvy, P.F.3
  • 9
    • 84863676425 scopus 로고    scopus 로고
    • Obesity and mental health-a complicated and complex relation
    • Sharma AM,. Obesity and mental health-a complicated and complex relation. Can J Psychiatry 2012; 57 (1): 3-4.
    • (2012) Can J Psychiatry , vol.57 , Issue.1 , pp. 3-4
    • Sharma, A.M.1
  • 10
    • 77949539959 scopus 로고    scopus 로고
    • The association between obesity and anxiety disorders in the population: A systematic review and meta-analysis
    • Gariepy G, Nitka D, Schmitz N,. The association between obesity and anxiety disorders in the population: a systematic review and meta-analysis. Int J Obes 2010; 34 (3): 407-19.
    • (2010) Int J Obes , vol.34 , Issue.3 , pp. 407-419
    • Gariepy, G.1    Nitka, D.2    Schmitz, N.3
  • 11
    • 0034630441 scopus 로고    scopus 로고
    • Overweight obesity health risk
    • National Task Force on the Prevention and Treatment of Obesity.
    • National Task Force on the Prevention and Treatment of Obesity. Overweight obesity health risk. Arch Intern Med 2000; 160 (3): 898-904.
    • (2000) Arch Intern Med , vol.160 , Issue.3 , pp. 898-904
  • 15
    • 0032040382 scopus 로고    scopus 로고
    • What is the economic case for treating obesity?
    • Wolf AM,. What is the economic case for treating obesity? Obes Res 2012; 6 (Suppl 1): 2S-7S.
    • (2012) Obes Res , vol.6 , Issue.SUPPL. 1
    • Wolf, A.M.1
  • 16
    • 0032162184 scopus 로고    scopus 로고
    • Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report
    • National Institutes of Health.
    • National Institutes of Health. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report. Obes Res 1998; 6 (Suppl 2): 51S-209S.
    • (1998) Obes Res , vol.6 , Issue.SUPPL. 2
  • 18
    • 0035212146 scopus 로고    scopus 로고
    • American College of Sports Medicine position stand. Appropriate intervention strategies for weight loss and prevention of weight regain for adults
    • Jakicic JM, Clark K, Coleman E, et al. American College of Sports Medicine position stand. Appropriate intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc 2001; 33 (12): 2145.
    • (2001) Med Sci Sports Exerc , vol.33 , Issue.12 , pp. 2145
    • Jakicic, J.M.1    Clark, K.2    Coleman, E.3
  • 19
    • 0003772710 scopus 로고    scopus 로고
    • US Department of Health and Human Services. Sudbury, MA: Jones & Bartlett Learning
    • US Department of Health and Human Services. Physical activity and health: a report of the Surgeon General. Sudbury, MA: Jones & Bartlett Learning 1996; 278 pp.
    • (1996) Physical Activity and Health: A Report of the Surgeon General , pp. 278
  • 20
    • 58149380069 scopus 로고    scopus 로고
    • US Department of Health and Human Services Be active, healthy, and happy (2008)
    • US Department of Health and Human Services. 2008 physical activity guidelines for Americans. Be active, healthy, and happy (2008). Available from http://www.health.gov/paguidelines/guidelines/default.aspx.
    • (2008) Physical Activity Guidelines for Americans
  • 21
    • 80051735396 scopus 로고    scopus 로고
    • Medications for weight reduction
    • Bray GA,. Medications for weight reduction. Med Clin North Am 2011; 95 (5): 989-1008.
    • (2011) Med Clin North Am , vol.95 , Issue.5 , pp. 989-1008
    • Bray, G.A.1
  • 22
    • 84859294995 scopus 로고    scopus 로고
    • Medical therapy for the patient with obesity
    • Bray GA, Ryan DH,. Medical therapy for the patient with obesity. Circulation 2012; 125 (13): 1695-703.
    • (2012) Circulation , vol.125 , Issue.13 , pp. 1695-1703
    • Bray, G.A.1    Ryan, D.H.2
  • 23
    • 84860330219 scopus 로고    scopus 로고
    • Food and Drug Administration's Obesity Drug Guidance Document: A short history
    • Colman E,. Food and Drug Administration's Obesity Drug Guidance Document: a short history. Circulation 2012; 125 (17): 2156-64.
    • (2012) Circulation , vol.125 , Issue.17 , pp. 2156-2164
    • Colman, E.1
  • 25
    • 67649379367 scopus 로고    scopus 로고
    • Serotonergic drugs and valvular heart disease
    • Rothman RB, Baumann MH,. Serotonergic drugs and valvular heart disease. Expert Opin Drug Saf 2009; 8 (3): 317-29.
    • (2009) Expert Opin Drug Saf , vol.8 , Issue.3 , pp. 317-329
    • Rothman, R.B.1    Baumann, M.H.2
  • 27
    • 0030876952 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Connolly HM, Crary JL, McGoon MD, et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 1997; 337 (9): 581-8.
    • (1997) N Engl J Med , vol.337 , Issue.9 , pp. 581-588
    • Connolly, H.M.1    Crary, J.L.2    McGoon, M.D.3
  • 28
    • 9444287592 scopus 로고    scopus 로고
    • Appetite-suppressant drugs and the risk of primary pulmonary hypertension
    • Abenhaim L, Moride Y, Brenot F, et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med 1996; 335 (9): 609-16.
    • (1996) N Engl J Med , vol.335 , Issue.9 , pp. 609-616
    • Abenhaim, L.1    Moride, Y.2    Brenot, F.3
  • 29
    • 84900844745 scopus 로고    scopus 로고
    • Fenfluramine-induced gene dysregulation in human pulmonary artery smooth muscle and endothelial cells
    • Yao W, Mu W, Zeifman A, et al. Fenfluramine-induced gene dysregulation in human pulmonary artery smooth muscle and endothelial cells. Pulm Circ 2011; 1 (3): 405-18.
    • (2011) Pulm Circ , vol.1 , Issue.3 , pp. 405-418
    • Yao, W.1    Mu, W.2    Zeifman, A.3
  • 30
    • 0032434821 scopus 로고    scopus 로고
    • Sibutramine. A review of its contribution to the management of obesity
    • McNeely W, Goa KL,. Sibutramine. A review of its contribution to the management of obesity. Drugs 1998; 56 (6): 1093-124.
    • (1998) Drugs , vol.56 , Issue.6 , pp. 1093-1124
    • McNeely, W.1    Goa, K.L.2
  • 31
    • 77956284607 scopus 로고    scopus 로고
    • Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
    • James WP, Caterson ID, Coutinho W, et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med 2010; 363 (10): 905-17.
    • (2010) N Engl J Med , vol.363 , Issue.10 , pp. 905-917
    • James, W.P.1    Caterson, I.D.2    Coutinho, W.3
  • 32
    • 18444376760 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
    • Howlett AC, Barth F, Bonner TI, et al. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 2002; 54 (2): 161-202.
    • (2002) Pharmacol Rev , vol.54 , Issue.2 , pp. 161-202
    • Howlett, A.C.1    Barth, F.2    Bonner, T.I.3
  • 33
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Group RI-ES.
    • Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rossner S, Group RI-ES. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005; 365 (9468): 1389-97.
    • (2005) Lancet , vol.365 , Issue.9468 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 34
    • 0032543870 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group
    • Sjöström L, Rissanen A, Andersen T, et al. Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group. Lancet 1998; 352 (9123): 167.
    • (1998) Lancet , vol.352 , Issue.9123 , pp. 167
    • Sjöström, L.1    Rissanen, A.2    Andersen, T.3
  • 35
    • 1042303480 scopus 로고    scopus 로고
    • XENical in the prevention of diabetes in obese subjects (XENDOS) study: A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
    • Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L,. XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 2004; 27 (1): 155-61.
    • (2004) Diabetes Care , vol.27 , Issue.1 , pp. 155-161
    • Torgerson, J.S.1    Hauptman, J.2    Boldrin, M.N.3    Sjostrom, L.4
  • 36
    • 20444446770 scopus 로고    scopus 로고
    • Effect of orlistat on weight and body composition in obese adolescents: A randomized controlled trial
    • Chanoine JP, Hampl S, Jensen C, Boldrin M, Hauptman J,. Effect of orlistat on weight and body composition in obese adolescents: a randomized controlled trial. JAMA 2005; 293 (23): 2873-83.
    • (2005) JAMA , vol.293 , Issue.23 , pp. 2873-2883
    • Chanoine, J.P.1    Hampl, S.2    Jensen, C.3    Boldrin, M.4    Hauptman, J.5
  • 37
    • 0031904104 scopus 로고    scopus 로고
    • Role of orlistat in the treatment of obese patients with type 2 diabetes. A 1-year randomized double-blind study
    • Hollander PA, Elbein SC, Hirsch IB, et al. Role of orlistat in the treatment of obese patients with type 2 diabetes. A 1-year randomized double-blind study. Diabetes Care 1998; 21 (8): 1288-94.
    • (1998) Diabetes Care , vol.21 , Issue.8 , pp. 1288-1294
    • Hollander, P.A.1    Elbein, S.C.2    Hirsch, I.B.3
  • 38
    • 0036598137 scopus 로고    scopus 로고
    • Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial
    • Kelley DE, Bray GA, Pi-Sunyer FX, et al. Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: a 1-year randomized controlled trial. Diabetes Care 2002; 25 (6): 1033-41.
    • (2002) Diabetes Care , vol.25 , Issue.6 , pp. 1033-1041
    • Kelley, D.E.1    Bray, G.A.2    Pi-Sunyer, F.X.3
  • 39
    • 0036634125 scopus 로고    scopus 로고
    • Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin
    • Miles JM, Leiter L, Hollander P, et al. Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin. Diabetes Care 2002; 25 (7): 1123-8.
    • (2002) Diabetes Care , vol.25 , Issue.7 , pp. 1123-1128
    • Miles, J.M.1    Leiter, L.2    Hollander, P.3
  • 40
    • 0034621494 scopus 로고    scopus 로고
    • Effects of weight loss with orlistat on glucose tolerance and progression to type 2 diabetes in obese adults
    • Heymsfield SB, Segal KR, Hauptman J, et al. Effects of weight loss with orlistat on glucose tolerance and progression to type 2 diabetes in obese adults. Arch Intern Med 2000; 160 (9): 1321-6.
    • (2000) Arch Intern Med , vol.160 , Issue.9 , pp. 1321-1326
    • Heymsfield, S.B.1    Segal, K.R.2    Hauptman, J.3
  • 41
    • 0032924255 scopus 로고    scopus 로고
    • Long-term systemic exposure of orlistat, a lipase inhibitor, and its metabolites in obese patients
    • Zhi J, Mulligan TE, Hauptman JB,. Long-term systemic exposure of orlistat, a lipase inhibitor, and its metabolites in obese patients. J Clin Pharmacol 1999; 39 (1): 41-6.
    • (1999) J Clin Pharmacol , vol.39 , Issue.1 , pp. 41-46
    • Zhi, J.1    Mulligan, T.E.2    Hauptman, J.B.3
  • 42
    • 37249083878 scopus 로고    scopus 로고
    • Long term pharmacotherapy for obesity and overweight: Updated meta-analysis
    • Rucker D, Padwal R, Li SK, Curioni C, Lau DC,. Long term pharmacotherapy for obesity and overweight: updated meta-analysis. BMJ 2007; 335 (7631): 1194-9.
    • (2007) BMJ , vol.335 , Issue.7631 , pp. 1194-1199
    • Rucker, D.1    Padwal, R.2    Li, S.K.3    Curioni, C.4    Lau, D.C.5
  • 43
    • 80455173623 scopus 로고    scopus 로고
    • Lorcaserin: An investigational serotonin 2C agonist for weight loss
    • Hurren KM, Berlie HD,. Lorcaserin: an investigational serotonin 2C agonist for weight loss. Am J Health Syst Pharm 2011; 68 (21): 2029-37.
    • (2011) Am J Health Syst Pharm , vol.68 , Issue.21 , pp. 2029-2037
    • Hurren, K.M.1    Berlie, H.D.2
  • 44
    • 77954635020 scopus 로고    scopus 로고
    • Multicenter, placebo-controlled trial of lorcaserin for weight management
    • Smith SR, Weissman NJ, Anderson CM, et al. Multicenter, placebo-controlled trial of lorcaserin for weight management. N Engl J Med 2010; 363 (3): 245-56.
    • (2010) N Engl J Med , vol.363 , Issue.3 , pp. 245-256
    • Smith, S.R.1    Weissman, N.J.2    Anderson, C.M.3
  • 45
    • 80053539943 scopus 로고    scopus 로고
    • A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: The BLOSSOM trial
    • Fidler MC, Sanchez M, Raether B, et al. A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab 2011; 96 (10): 3067-77.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.10 , pp. 3067-3077
    • Fidler, M.C.1    Sanchez, M.2    Raether, B.3
  • 46
    • 84862869642 scopus 로고    scopus 로고
    • Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: The BLOOM-DM Study
    • O'Neil PM, Smith SR, Weissman NJ, et al. Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM Study. Obesity (Silver Spring) 2012; 20 (7): 1426-36.
    • (2012) Obesity (Silver Spring) , vol.20 , Issue.7 , pp. 1426-1436
    • O'Neil, P.M.1    Smith, S.R.2    Weissman, N.J.3
  • 51
    • 84856246606 scopus 로고    scopus 로고
    • Controlled-release phentermine/topiramate in severely obese adults: A randomized controlled trial (EQUIP)
    • Allison DB, Gadde KM, Garvey WT, et al. Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring) 2012; 20 (2): 330-42.
    • (2012) Obesity (Silver Spring) , vol.20 , Issue.2 , pp. 330-342
    • Allison, D.B.1    Gadde, K.M.2    Garvey, W.T.3
  • 52
    • 79954561234 scopus 로고    scopus 로고
    • Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): A randomised, placebo-controlled, phase 3 trial
    • Gadde KM, Allison DB, Ryan DH, et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet 2011; 377 (9774): 1341-52.
    • (2011) Lancet , vol.377 , Issue.9774 , pp. 1341-1352
    • Gadde, K.M.1    Allison, D.B.2    Ryan, D.H.3
  • 53
    • 84856388467 scopus 로고    scopus 로고
    • Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study
    • Garvey WT, Ryan DH, Look M, et al. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr 2012; 95 (2): 297-308.
    • (2012) Am J Clin Nutr , vol.95 , Issue.2 , pp. 297-308
    • Garvey, W.T.1    Ryan, D.H.2    Look, M.3
  • 55
    • 84886674345 scopus 로고    scopus 로고
    • FDA.gov Accessed August 1
    • FDA.gov. FDA approves weight-management drug Qsymia. Avaialble from http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm312468.htm. Accessed August 1, 2012.
    • (2012) FDA Approves Weight-management Drug Qsymia
  • 56
    • 77956057548 scopus 로고    scopus 로고
    • Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): A multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
    • Greenway FL, Fujioka K, Plodkowski RA, et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 2010; 376 (9741): 595-605.
    • (2010) Lancet , vol.376 , Issue.9741 , pp. 595-605
    • Greenway, F.L.1    Fujioka, K.2    Plodkowski, R.A.3
  • 57
    • 77956904326 scopus 로고    scopus 로고
    • Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial
    • Wadden TA, Foreyt JP, Foster GD, et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring) 2011; 19 (1): 110-20.
    • (2011) Obesity (Silver Spring) , vol.19 , Issue.1 , pp. 110-120
    • Wadden, T.A.1    Foreyt, J.P.2    Foster, G.D.3
  • 60
    • 78149304467 scopus 로고    scopus 로고
    • Bristol-Myers Squibb Company. Princeton, NJ: Bristol-Myers Squibb Company.
    • ® (metformin hydrochloride) package insert. Princeton, NJ: Bristol-Myers Squibb Company; 2009.
    • (2009) ® (Metformin Hydrochloride) Package Insert
  • 61
    • 70449517253 scopus 로고    scopus 로고
    • Ten-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study
    • Diabetes Prevention Program Research Group, et al.
    • Diabetes Prevention Program Research Group, Knowler WC, Fowler SE, et al. Ten-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet 2009; 374 (9702): 1677-86.
    • (2009) Lancet , vol.374 , Issue.9702 , pp. 1677-1686
    • Knowler, W.C.1    Fowler, S.E.2
  • 62
    • 84859372038 scopus 로고    scopus 로고
    • Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study
    • Diabetes Prevention Program Research Group.
    • Diabetes Prevention Program Research Group. Long-term safety, tolerability, and weight loss associated with metformin in the Diabetes Prevention Program Outcomes Study. Diabetes Care 2012; 35 (4): 731-7.
    • (2012) Diabetes Care , vol.35 , Issue.4 , pp. 731-737
  • 63
    • 84872617193 scopus 로고    scopus 로고
    • Effectiveness of metformin on weight loss in non-diabetic individuals with obesity
    • Seifarth C, Schehler B, Schneider HJ,. Effectiveness of metformin on weight loss in non-diabetic individuals with obesity. Exp Clin Endocrinol Diabetes 2013; 121 (01): 27-31.
    • (2013) Exp Clin Endocrinol Diabetes , vol.121 , Issue.1 , pp. 27-31
    • Seifarth, C.1    Schehler, B.2    Schneider, H.J.3
  • 64
    • 70449526185 scopus 로고    scopus 로고
    • Effects of 1-year treatment with metformin on metabolic and cardiovascular risk factors in non-diabetic upper-body obese subjects with mild glucose anomalies: A post-hoc analysis of the BIGPRO1 trial
    • Fontbonne A, Diouf I, Baccara-Dinet M, Eschwege E, Charles MA,. Effects of 1-year treatment with metformin on metabolic and cardiovascular risk factors in non-diabetic upper-body obese subjects with mild glucose anomalies: a post-hoc analysis of the BIGPRO1 trial. Diabetes Metab 2009; 35 (5): 385-91.
    • (2009) Diabetes Metab , vol.35 , Issue.5 , pp. 385-391
    • Fontbonne, A.1    Diouf, I.2    Baccara-Dinet, M.3    Eschwege, E.4    Charles, M.A.5
  • 66
    • 0038516857 scopus 로고    scopus 로고
    • Zonisamide for weight loss in obese adults: A randomized controlled trial
    • Gadde KM, Franciscy DM, Wagner HR 2nd, Krishnan KR,. Zonisamide for weight loss in obese adults: a randomized controlled trial. JAMA 2003; 289 (14): 1820-5.
    • (2003) JAMA , vol.289 , Issue.14 , pp. 1820-1825
    • Gadde, K.M.1    Franciscy, D.M.2    Wagner II, H.R.3    Krishnan, K.R.4
  • 67
  • 68
    • 17144371646 scopus 로고    scopus 로고
    • Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
    • Kendall DM, Riddle MC, Rosenstock J, et al. Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 2005; 28 (5): 1083-91.
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1083-1091
    • Kendall, D.M.1    Riddle, M.C.2    Rosenstock, J.3
  • 69
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Buse JB, Henry RR, Han J, et al. Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004; 27 (11): 2628-35.
    • (2004) Diabetes Care , vol.27 , Issue.11 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3
  • 70
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (Exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • DeFronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, Baron AD,. Effects of exenatide (Exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005; 28 (5): 1092-100.
    • (2005) Diabetes Care , vol.28 , Issue.5 , pp. 1092-1100
    • Defronzo, R.A.1    Ratner, R.E.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 71
    • 33947156808 scopus 로고    scopus 로고
    • Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: An interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials
    • Buse JB, Klonoff DC, Nielsen LL, et al. Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials. Clin Ther 2007; 29 (1): 139-53.
    • (2007) Clin Ther , vol.29 , Issue.1 , pp. 139-153
    • Buse, J.B.1    Klonoff, D.C.2    Nielsen, L.L.3
  • 72
    • 77956090389 scopus 로고    scopus 로고
    • Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes
    • Rosenstock J, Klaff LJ, Schwartz S, et al. Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes. Diabetes Care 2010; 33 (6): 1173-5.
    • (2010) Diabetes Care , vol.33 , Issue.6 , pp. 1173-1175
    • Rosenstock, J.1    Klaff, L.J.2    Schwartz, S.3
  • 73
    • 0026353971 scopus 로고
    • Gastrointestinal surgery for severe obesity. Consensus Development Conference Panel
    • NIH Conference.
    • NIH Conference. Gastrointestinal surgery for severe obesity. Consensus Development Conference Panel. Ann Intern Med 1991; 115 (12): 956-61.
    • (1991) Ann Intern Med , vol.115 , Issue.12 , pp. 956-961
  • 74
    • 80051768496 scopus 로고    scopus 로고
    • Surgical approaches to the treatment of obesity: Bariatric surgery
    • Smith BR, Schauer P, Nguyen NT,. Surgical approaches to the treatment of obesity: bariatric surgery. Med Clin North Am 2011; 95 (5): 1009-30.
    • (2011) Med Clin North Am , vol.95 , Issue.5 , pp. 1009-1030
    • Smith, B.R.1    Schauer, P.2    Nguyen, N.T.3
  • 75
    • 28444474250 scopus 로고    scopus 로고
    • Effect of bariatric surgery on long-term mortality
    • Christou NV, MacLean LD,. Effect of bariatric surgery on long-term mortality. Adv Surg 2005; 39: 165-79.
    • (2005) Adv Surg , vol.39 , pp. 165-179
    • Christou, N.V.1    Maclean, L.D.2
  • 76
    • 34548090763 scopus 로고    scopus 로고
    • Effects of bariatric surgery on mortality in Swedish obese subjects
    • Sjostrom L, Narbro K, Sjostrom CD, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 2007; 357 (8): 741-52.
    • (2007) N Engl J Med , vol.357 , Issue.8 , pp. 741-752
    • Sjostrom, L.1    Narbro, K.2    Sjostrom, C.D.3
  • 77
    • 5044242948 scopus 로고    scopus 로고
    • Bariatric surgery: A systematic review and meta-analysis
    • Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 2004; 292 (14): 1724-37.
    • (2004) JAMA , vol.292 , Issue.14 , pp. 1724-1737
    • Buchwald, H.1    Avidor, Y.2    Braunwald, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.