Infantile exposure to lead and late-age cognitive decline: Relevance to AD

Alzheimer's and Dementia

Volumn 10, Issue 2, 2014, Pages 187-195

  Bihaqi, Syed Waseem ^a   Bahmani, Azadeh ^a   Subaiea, Gehad M ^a   Zawia, Nasser H ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Aging; Alzheimer's disease; Cognition; Development; Lead; Life span

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; BIOLOGICAL MARKER; LEAD; MESSENGER RNA; TRANSCRIPTION FACTOR SP1;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; LIFESPAN; MAZE TEST; MOUSE; NONHUMAN; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

AGING; ALZHEIMER'S DISEASE; COGNITION; DEVELOPMENT; LEAD; LIFE SPAN;

AGING; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANIMALS, NEWBORN; ANTIMICROBIAL CATIONIC PEPTIDES; ASPARTIC ACID ENDOPEPTIDASES; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; LEAD; MALE; MAZE LEARNING; MICE; PEPTIDE FRAGMENTS; RNA, MESSENGER;

EID: 84897495382     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2013.02.012     Document Type: Article

References (27)

1. D.J. Selkoe Amyloid protein and Alzheimer's disease Sci Am 265 1991 68 71 74-6, 78
2. R.E. Tanzi, and L. Bertram Alzheimer's disease: the latest suspect Nature 454 2008 706 708
3. M.R. Basha, W. Wei, S.A. Bakheet, N. Benitez, H.K. Siddiqi, and Y.W. Ge et al. The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain J Neurosci 25 2005 823 829
4. J. Wu, M.R. Basha, B. Brock, D.P. Cox, F. Cardozo-Pelaez, and C.A. McPherson et al. Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD J Neurosci 28 2008 3 9
5. H. Alashwal, R. Dosunmu, and N.H. Zawia Integration of genome-wide expression and methylation data: relevance to aging and Alzheimer's disease Neurotoxicology 33 2012 1450 1453
6. R. Dosunmu, H. Alashwal, and N.H. Zawia Genome-wide expression and methylation profiling in the aged rodent brain due to early-life Pb exposure and its relevance to aging Mech Ageing Dev 133 2012 435 443
7. M. Payton, K.M. Riggs, A. Spiro 3rd, S.T. Weiss, and H. Hu Relations of bone and blood lead to cognitive function: the VA Normative Aging Study Neurotoxicol Teratol 20 1998 19 27
8. M.G. Weisskopf, R.O. Wright, J. Schwartz, A. Spiro 3rd, D. Sparrow, and A. Aro et al. Cumulative lead exposure and prospective change in cognition among elderly men: the VA Normative Aging Study Am J Epidemiol 160 2004 1184 1193
9. M.G. Weisskopf, S.P. Proctor, R.O. Wright, J. Schwartz, A. Spiro 3rd, and D. Sparrow et al. Cumulative lead exposure and cognitive performance among elderly men Epidemiology 18 2007 59 66
10. R.O. Wright, S.W. Tsaih, J. Schwartz, A. Spiro 3rd, K. McDonald, and S.T. Weiss et al. Lead exposure biomarkers and Mini-Mental Status Exam scores in older men Epidemiology 14 2003 713 718
11. J. Weuve, S.A. Korrick, M.G. Weisskopf, L.M. Ryan, J. Schwartz, and H. Nie et al. Cumulative exposure to lead in relation to cognitive function in older women Environ Health Perspect 117 2009 574 580
12. R. Dosunmu, J. Wu, L. Adwan, B. Maloney, M.R. Basha, and C.A. McPherson et al. Life span profiles of Alzheimer's disease-associated genes and products in monkeys and mice J Alzheimers Dis 18 2009 211 230
13. R.G. Morris, P. Garrud, J.N. Rawlins, and J. O'Keefe Place navigation impaired in rats with hippocampal lesions Nature 297 1982 681 683
14. M. Sarter, G. Bodewitz, and D.N. Stephens Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines Psychopharmacology (Berl) 94 1988 491 495
15. M. Morishima-Kawashima, N. Oshima, H. Ogata, H. Yamaguchi, M. Yoshimura, and S. Sugihara et al. Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain Am J Pathol 157 2000 2093 2099
16. M.R. Basha, M. Murali, H.K. Siddiqi, K. Ghosal, O.K. Siddiqi, and H.A. Lashuel et al. Lead (Pb) exposure and its effect on APP proteolysis and Abeta aggregation FASEB J 19 2005 2083 2084
17. S. Tong, Y.E. von Schirnding, and T. Prapamontol Environmental lead exposure: a public health problem of global dimensions Bull World Health Organ 78 2000 1068 1077
18. L. Patrick Lead toxicity, a review of the literature. Part 1: exposure, evaluation, and treatment Altern Med Rev 11 2006 2 22
19. R.L. Canfield, C.R. Henderson Jr., D.A. Cory-Slechta, C. Cox, T.A. Jusko, and B.P. Lanphear Intellectual impairment in children with blood lead concentrations below 10 μg per deciliter N Engl J Med 348 2003 1517 1526
20. H. Huang, S.W. Bihaqi, L. Cui, and N.H. Zawia In vitro Pb exposure disturbs the balance between Abeta production and elimination: the role of AbetaPP and neprilysin Neurotoxicology 32 2011 300 306
21. S.W. Bihaqi, and N.H. Zawia Alzheimer's disease biomarkers and epigenetic intermediates following exposure to Pb in vitro Curr Alzheimer Res 9 2012 555 562
22. F. Docagne, C. Gabriel, N. Lebeurrier, S. Lesne, Y. Hommet, and L. Plawinski et al. Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription Biochem J 383 2004 393 399
23. W.J. Lukiw, E.I. Rogaev, L. Wong, G. Vaula, D.R. McLachlan, and P. St. George Hyslop Protein-DNA interactions in the promoter region of the amyloid precursor protein (APP) gene in human neocortex Brain Res Mol Brain Res 22 1994 121 131
24. B. Brock, R. Basha, K. DiPalma, A. Anderson, G.J. Harry, and D.C. Rice et al. Co-localization and distribution of cerebral APP and SP1 and its relationship to amyloidogenesis J Alzheimers Dis 13 2008 71 80
25. P. Pollwein, C.L. Masters, and K. Beyreuther The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter Nucl Acids Res 20 1992 63 68
26. S.W. Bihaqi, H. Huang, J. Wu, and N.H. Zawia Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain: implications for Alzheimer's disease J Alzheimers Dis 27 2011 819 833
27. A.M. Oliveira, T.J. Hemstedt, and H. Bading Rescue of aging-associated decline in DNMT3a2 expression restores cognitive abilities Nat Neurosci 15 2012 1111 1113