Autophagy-targeted vaccine of LC3-LpqH DNA and its protective immunity in a murine model of tuberculosis

Vaccine

Volumn 32, Issue 20, 2014, Pages 2308-2314

  Hu, Dong ^a   Wu, Jing ^a   Zhang, Rongbo ^a   Chen, Liping ^a   Chen, Zhaoquan ^a   Wang, Xuefeng ^a   Xu, Lifa ^a   Xiao, Jian ^b   Hu, Fengyu ^c   Wu, Changyou ^c  

^a ANHUI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Ag85B; Autophagy; LC3; LpqH; Mycobacterium tuberculosis; Protective immunity

Indexed keywords

BACTERIAL PROTEIN; BCG VACCINE; DNA VACCINE; GAMMA INTERFERON; HYBRID PROTEIN; IMMUNOGLOBULIN G2A; INTERLEUKIN 2; LC3 LPQH FUSED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; RAPAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BACTERIAL LOAD; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GENETIC TRANSFECTION; IMMUNE RESPONSE; LUNG; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; SPLEEN; SPLEEN CELL; TUBERCULOSIS; WESTERN BLOTTING;

AG85B; AUTOPHAGY; LC3; LPQH; MYCOBACTERIUM TUBERCULOSIS; PROTECTIVE IMMUNITY;

ANIMALS; ANTIBODIES, BACTERIAL; AUTOPHAGY; BACTERIAL LOAD; BACTERIAL PROTEINS; CELL LINE; CYTOKINES; FEMALE; LIPOPROTEINS; LUNG; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; PHAGOSOMES; RECOMBINANT FUSION PROTEINS; SPLEEN; TUBERCULOSIS; TUBERCULOSIS VACCINES; VACCINES, DNA;

EID: 84897481849     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.02.069     Document Type: Article

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