Highly efficient expression of interleukin-2 under the control of rabbit β-globin intron ii gene enhances protective immune responses of porcine reproductive and respiratory syndrome (PRRS) DNA vaccine in pigs

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Du, Yijun ^a,b   Lu, Yu ^c   Wang, Xinglong ^d   Qi, Jing ^a,b   Liu, Jiyu ^b   Hu, Yue ^e   Li, Feng ^f   Wu, Jiaqiang ^b   Guo, Lihui ^b   Liu, Junzhen ^b   Tao, Haiying ^b   Sun, Wenbo ^b   Chen, Lei ^a,b   Cong, Xiaoyan ^a,b   Ren, Sufang ^b   Shi, Jianli ^b   Li, Jun ^b   Wang, Jinbao ^a,b,e   Huang, Baohua ^b   Wan, Renzhong ^e  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG PEANUT RESEARCH INSTITUTE   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d NORTHWEST A F UNIVERSITY   (China)

^e SHANDONG AGRICULTURAL UNIVERSITY   (China)

^f SOUTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; HYBRID PROTEIN; INTERLEUKIN 2; CYTOKINE; GLYCOPROTEIN; HEMOGLOBIN BETA CHAIN; VIRUS ANTIBODY; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTERIVIRUS; ARTERIVIRUS INFECTION; ARTICLE; BETA GLOBIN INTRON II GENE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EXPRESSION VECTOR; FEMALE; GENE; GENETIC TRANSFECTION; HUMORAL IMMUNITY; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; T LYMPHOCYTE; VACCINATION; VIRUS STRAIN; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BLOOD; CELL PROLIFERATION; GENE EXPRESSION; GENE VECTOR; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; INTRON; LYMPHOCYTE; METABOLISM; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; RABBIT; VIROLOGY;

ANIMALS; ANTIBODIES, VIRAL; BETA-GLOBINS; BLOTTING, WESTERN; CELL PROLIFERATION; CYTOKINES; FEMALE; GENE EXPRESSION; GENETIC VECTORS; GLYCOPROTEINS; HEK293 CELLS; HUMANS; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; INTERLEUKIN-2; INTRONS; LYMPHOCYTES; MICE, INBRED BALB C; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWINE; VACCINES, DNA; VIRAL PROTEINS;

EID: 84897458921     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090326     Document Type: Article

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