Mice with targeted inactivation of Ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 4, 2014, Pages 837-845

  Panchatcharam, Manikandan ^a   Salous, Abdel K ^a   Brandon, Jason ^a   Miriyala, Sumitra ^a   Wheeler, Jessica ^a   Patil, Pooja ^a   Sunkara, Manjula ^a   Morris, Andrew J ^a,c   Escalante Alcalde, Diana ^b   Smyth, Susan S ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c LEXINGTON VA MEDICAL CENTER   (United States)

Author keywords

autotaxin protein; capillary permeability; endothelial cells; hematopoietic stem cells; human; lysophosphatidic acid

Indexed keywords

AUTOTAXIN; CRE RECOMBINASE; ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; HYBRID PROTEIN; LIPID PHOSPHATE PHOSPHATASE 3; LYSOPHOSPHOLIPASE; PHOSPHATASE; PROTEIN TYROSINE KINASE; TAMOXIFEN; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL FUNCTION; CONTROLLED STUDY; EMBRYO; EMBRYONIC LETHALITY; ENDOTHELIUM CELL; ENZYME DEFICIENCY; FEMALE; GENE; GENE DELETION; GENE INACTIVATION; GENE TARGETING; HEMATOPOIETIC CELL; IMMUNOHISTOCHEMISTRY; INDEL MUTATION; INFLAMMATION; INFLAMMATORY CELL; LETHALITY; MALE; MOUSE; NONHUMAN; NULL ALLELE; PPAP2B GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; TRANSGENE; VASCULAR DISEASE; VASCULAR LEAK; VASCULITIS;

AUTOTAXIN PROTEIN, HUMAN; CAPILLARY PERMEABILITY; ENDOTHELIAL CELLS; HEMATOPOIETIC STEM CELLS; LYSOPHOSPHATIDIC ACID;

ANIMALS; CAPILLARY PERMEABILITY; CYTOKINES; ENDOTHELIAL CELLS; GENOTYPE; HEMATOPOIETIC STEM CELLS; INFLAMMATION; INFLAMMATION MEDIATORS; INTEGRASES; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; PHOSPHATIDATE PHOSPHATASE; PHOSPHORIC DIESTER HYDROLASES; PROMOTER REGIONS, GENETIC; RECEPTOR, TIE-2; RECEPTORS, LYSOPHOSPHATIDIC ACID; SIGNAL TRANSDUCTION; TRANSGENES;

EID: 84897457308     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.113.302335     Document Type: Article

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