Zingerone regulates intestinal transit, attenuates behavioral and oxidative perturbations in irritable bowel disorder in rats

Phytomedicine

Volumn 21, Issue 4, 2014, Pages 423-429

  Banji, David ^a   Banji, Otilia J F ^a   Pavani, Bandlapalli ^a   Kranthi Kumar, Ch ^b   Annamalai, A R ^b  

^a Nalanda College of Pharmacy   (India)

^b ANNAMALAI UNIVERSITY   (India)

Author keywords

Colonic transit; Mast cells; Myeloperoxidase; Zingerone; Zingiber officinalis

Indexed keywords

CATALASE; CORTICOSTERONE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDE; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE; ZINGERONE; GUAIACOL; PLANT EXTRACT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; BEHAVIOR; BEHAVIOR CHANGE; CELL INFILTRATION; CHRONIC STRESS; COLON HOMOGENATE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; ENZYME ACTIVITY; FECES ANALYSIS; GASTROINTESTINAL TRANSIT; HOMOGENATE; IRRITABLE COLON; LIPID PEROXIDATION; MALE; MAST CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; WATER STRESS; WEIGHT CHANGE; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; BODY WEIGHT; COLON; DRUG EFFECTS; DRUG SCREENING; GINGER; IRRITABLE BOWEL SYNDROME; MAZE TEST; PHYTOTHERAPY; RANDOMIZATION; WISTAR RAT;

RATTUS; ZINGIBER;

ANIMALS; BODY WEIGHT; COLON; CORTICOSTERONE; DRUG EVALUATION, PRECLINICAL; GASTROINTESTINAL TRANSIT; GINGER; GUAIACOL; IRRITABLE BOWEL SYNDROME; MALE; MAZE LEARNING; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; RANDOM ALLOCATION; RATS, WISTAR;

EID: 84897445667     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.10.007     Document Type: Article

References (47)

1. H. Aebi Catalase in vitro Methods Enzymol. 105 1984 121 126
2. M. Afzal, A. Afzal, A. Jones, and D. Armstrong A rapid method for the quantification of GSH and GSSG in biological samples Methods Mol. Biol. 186 2002 117 122
3. H. Anisman, and R.M. Zacharko Multiple neurochemical and behavioral consequences of stressors: implication for depression Psychopharmacology of Anxiolytics and Antidepressants 1991 Pergamon Press New York 57 82
4. K.P. Bargava, and N. Singh Effect of Ocimum sanctum on noise induced changes in neutrophil functions Ind. J. Med. Res. 73 1981 143 151
5. P.P. Bradley, D.A. Priebat, R.D. Christensen, and G. Rothstein Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker J. Invest. Dermatol. 78 1982 206 209
6. M. Broccardo, G. Improta, and A. Tabacco Central effect of SNC80, a selective and systemically active delta-opioid receptor agonist, on gastrointestinal propulsion in the mouse Eur. J. Pharmacol. 342 1998 247 251
7. J.R. Caso, J.C. Leza, and L. Menchen The effects of physical and psychological stress on the gastrointestinal tract: lessons from animal models Curr. Mol. Med. 8 2008 299 312
8. G.P. Chrousos Stress and disorders of the stress system Nat. Rev. Endocrinol. 5 2009 374 381
9. G. Ellman Tissue sulfhydril groups Arch. Biochem. Biophys. 82 1959 70 77
10. L. Ferrier Significance of increased human colonic permeability in response to corticotrophin-releasing hormone (CRH) Gut 57 2008 7 9
11. A. Garakani, and T. Win et al. Comorbidity of irritable bowel syndrome in psychiatric patients: a review Am. J. Ther. 10 1 2003 61 67
12. E. Guthrie, F. Creed, and L. Fernandes et al. Cluster analysis of symptoms and health seeking behavior differentiates subgroups of patients with severe irritable bowel syndrome Gut 52 2003 1616 1622
13. M. Iwami, T. Shiina, H. Hirayama, T. Shima, T. Takewaki, and Y. Yasutake Shimizu Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats J. Nat. Med. 65 2011 89 94
14. M.P. Jones, J.B. Dilley, D. Drossman, and M.D. Crowell Brain-gut connections in functional GI disorders: anatomic and physiologic relationships Neurogastroenterol. Motil. 18 2006 91 103
15. H. Kabuto, M. Nishizawa, M. Tada, C. Higashio, T. Shishibori, and M. Kohno Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum Neurochem. Res. 30 2005 325 332
16. K. Karalis, H. Sano, J. Redwine, S. Listwak, R.L. Wilder, and G.P. Chrousos Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo Science 254 1991 421 423
17. K.M. Kim, S.W. Chung, and D.H. Kim et al. Modulation of age-related NF-jB activation by dietary zingerone via MAPK pathway Exp. Gerontol. 45 2010 419 426
18. L. Keefer, J.L. Kiebles, and T.H. Taft Psychological Co-Morbidities of Irritable Bowel Syndrome. Psychological Co-Morbidities of Physical Illness 2011 385 414
19. J.E. Krawisz, P. Sharon, and W.F. Stenson Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity: assessment of inflammation in the rat and hamster model Gastroenterology 87 1984 1344 1350
20. M. Larauche, G. Gourcerol, and L. Wang et al. Cortagine, a CRF1 agonist, induces stresslike alterations of colonic function and visceral hypersensitivity in rodents primarily through peripheral pathways Am. J. Physiol. Gastrointest. Liver Physiol. 297 2009 G215 G227
21. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J. Biol. Chem. 193 1951 265 275
22. P.S. Masand, N.J. Keuthen, S. Gupta, S. Virk, B. Yu-Siao, and D. Kaplan Prevalence of irritable bowel syndrome in obsessive-compulsive disorder CNS Spectr. 11 2006 21 25
23. D. Mattingly A simple fluorimetric method for the estimation of free 11-hydroxysteroids in human plasma J. Clin. Pathol. 15 1962 374 379
24. B.S. McEwen Stress, adaptation, and disease. Allostasis and allostatic load Ann. N.Y. Acad. Sci. 840 1998 33 44
25. B.S. McEwen, and E. Stellar Stress and the individual, mechanisms leading to disease Arch. Int. Med. 153 1993 2093 2101
26. M. Miampamba, C. Maillot, M. Million, and Y. Tache Peripheral CRF activates myenteric neurons in the proximal colon through CRF(1) receptor in conscious rats Am. J. Physiol. Gastrointest. Liver Physiol. 282 2002 G857 G865
27. V. Miller, L. Hopkins, and P.J. Whorwell Suicidal ideation in patients with irritable bowel syndrome Clin. Gastroenterol. Hepatol. 2 2004 1064 1068
28. H.P. Misra, and I. Fridovich The role of superoxide anion in the autooxidation of epinephrine and simple assay for superoxide dismutase J. Biol. Chem. 247 1972 3170 3175
29. H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358
30. D.E. Paglia, and W.N. Valentine Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J. Lab. Clin. Med. 70 1967 158 169
31. J.H. Park, P.L. Rhee, H.S. Kim, J.H. Lee, Y.H. Kim, J.J. Kim, and J.C. Rhee Mucosal mast cell counts correlate with visceral hypersensitivity in patient's with diarrhea predominant irritable bowel syndrome J. Gastroenterol. Hepatol. 21 2006 71 78
32. S. Pellow, P. Chopin, S.E. File, and M. Briley Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat J. Neurosci. Methods 14 3 1985 149 167
33. P. Pulbutr, K. Thunchomnang, K. Lawa, A. Mangkhalathon, and P. Saenubol Lipolytic effects of zingerone in adipocytes isolated from normal diet fed rats and high fat diet fed rats Int. J. Pharmacol. 7 2011 629 634
34. B.N. Rao, B.S. Rao, B.K. Aithal, and M.R. Kumar Radiomodifying and anticlastogenic effect of Zingerone on Swiss albino mice exposed to whole body gamma radiation Mutat. Res. 677 2009 33 41
35. B.N. Rao, P.R. Archana, B.K. Aithal, and B.S. Rao Protective effect of zingerone, a dietary compound against radiation induced genetic damage and apoptosis in human lymphocytes Eur. J. Pharmacol. 657 2011 59 66
36. E. Rey, and N.J. Talley Irritable bowel syndrome: novel views on the epidemiology and potential risk factors Dig. Liver Dis. 41 2009 772 780
37. S.G. Shin, J.Y. Kim, H.Y. Chung, and J.C. Jeong Zingerone as an antioxidant against peroxynitrite J. Agric. Food Chem. 53 2005 7617 7622
38. H. Shoji, and K. Mizoguchi Acute and repeated stress differentially regulates behavioral, endocrine, neural parameters relevant to emotional and stress response in young and aged rats Behav. Brain Res. 211 2010 169 177
39. F.A.M. Silva, F. Boryer, C. Guimaraes, J.L.F.C. Lima, C. Matos, and C. Reis Phenolic acids and derivatives: studies on the relationship among structure, radical scavenging activity and physicochemical parameters J. Agric. Food Chem. 48 2000 2122 2126
40. G. Singh, P. Marimuthu, C.S. de Heluani, and C. Catalan Antimicrobial and antioxidant potentials of essential oil and acetone extract of Myristica fragrans Houtt (Aril part) J. Food Sci. 70 2005 M141 M148
41. G. Singh, P. Marimuthu, H.S. Murali, and A.S. Bawa Antioxidative and antimicrobial potentials of essential oils and extracts isolated from various spice materials J. Food Saf. 25 2005 130 145
42. A. Stengel, and Y. Taché Corticotropin-releasing factor signaling and visceral response to stress Exp. Biol. Med. (Maywood) 235 2010 1168 1178
43. A. Subarnas, T. Tadano, N. Nakahata, Y. Arai, and H. Kinemuchi et al. A possible mechanism of antidepressant activity of beta-amyrin palmitate isolated from Lobelia inflata leaves in the forced swimming test Life Sci. 52 1993 289 296
44. N. Sudo, Y. Chida, Y. Aiba, J. Sonoda, N. Oyama, and X.N. Yu et al. Postnatal microbial colonisation programs the hypothalamic-pituitaryadrenal system for stress response in mice J. Physiol. 558 2004 263 275
45. Y. Taché, and B. Bonaz Corticotropin-releasing factor receptors and stress related alterations of gut motor function J. Clin. Invest. 117 2007 33 40
46. K. Venkova, A.C. Johnson, B. Myers, and M.B. Greenwood-Van Exposure of the amygdala to elevated levels of corticosterone alters colonic motility in response to acute psychological stress Neuropharmacology 58 2010 1161 1167
47. G.J. Wetscher, M. Bagchi, D. Bagchi, G. Perdikis, P.R. Hinder, K. Giaser, and R.A. Hinder Free radicals production in nicotine-treated pancreatic tissue Free Radic. Biol. Med. 18 1995 877 882