메뉴 건너뛰기




Volumn 10, Issue 3, 2014, Pages

RON5 Is Critical for Organization and Function of the Toxoplasma Moving Junction Complex

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MEMBRANE PROTEIN; RHOPTRY NECK PROTEIN RON2; RHOPTRY NECK PROTEIN RON4; RHOPTRY NECK PROTEIN RON5; RHOPTRY NECK PROTEIN RON8; UNCLASSIFIED DRUG;

EID: 84897442989     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004025     Document Type: Article
Times cited : (50)

References (63)
  • 2
    • 0023734723 scopus 로고
    • Progress in taxonomy of the Apicomplexan protozoa
    • Levine ND, (1988) Progress in taxonomy of the Apicomplexan protozoa. J Protozool 35: 518-520.
    • (1988) J Protozool , vol.35 , pp. 518-520
    • Levine, N.D.1
  • 3
    • 26044470703 scopus 로고    scopus 로고
    • Biology and epidemiology of Toxoplasma gondii in man and animals
    • Hill DE, Chirukandoth S, Dubey JP, (2005) Biology and epidemiology of Toxoplasma gondii in man and animals. Anim Health Res Rev 6: 41-61.
    • (2005) Anim Health Res Rev , vol.6 , pp. 41-61
    • Hill, D.E.1    Chirukandoth, S.2    Dubey, J.P.3
  • 4
    • 7444266246 scopus 로고    scopus 로고
    • Clinical features and pathogenesis of severe malaria
    • Mackintosh CL, Beeson JG, Marsh K, (2004) Clinical features and pathogenesis of severe malaria. Trends Parasitol 20: 597-603.
    • (2004) Trends Parasitol , vol.20 , pp. 597-603
    • Mackintosh, C.L.1    Beeson, J.G.2    Marsh, K.3
  • 6
    • 0030956863 scopus 로고    scopus 로고
    • Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts
    • Carruthers VB, Sibley LD, (1997) Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts. Eur J Cell Biol 73: 114-123.
    • (1997) Eur J Cell Biol , vol.73 , pp. 114-123
    • Carruthers, V.B.1    Sibley, L.D.2
  • 7
  • 8
    • 77957371578 scopus 로고    scopus 로고
    • How apicomplexan parasites move in and out of cells
    • Sibley LD, (2010) How apicomplexan parasites move in and out of cells. Curr Opin Biotechnol 21: 592-598.
    • (2010) Curr Opin Biotechnol , vol.21 , pp. 592-598
    • Sibley, L.D.1
  • 9
    • 84873406471 scopus 로고    scopus 로고
    • Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms
    • Andenmatten N, Egarter S, Jackson AJ, Jullien N, Herman JP, et al. (2013) Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms. Nat Methods 10: 125-127.
    • (2013) Nat Methods , vol.10 , pp. 125-127
    • Andenmatten, N.1    Egarter, S.2    Jackson, A.J.3    Jullien, N.4    Herman, J.P.5
  • 10
    • 33846860640 scopus 로고    scopus 로고
    • Pulling together: an integrated model of Toxoplasma cell invasion
    • Carruthers V, Boothroyd JC, (2007) Pulling together: an integrated model of Toxoplasma cell invasion. Curr Opin Microbiol 10: 83-89.
    • (2007) Curr Opin Microbiol , vol.10 , pp. 83-89
    • Carruthers, V.1    Boothroyd, J.C.2
  • 11
    • 77951026559 scopus 로고    scopus 로고
    • Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles
    • Alexander DL, Mital J, Ward GE, Bradley P, Boothroyd JC, (2005) Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles. PLoS Pathog 1: e17.
    • (2005) PLoS Pathog , vol.1
    • Alexander, D.L.1    Mital, J.2    Ward, G.E.3    Bradley, P.4    Boothroyd, J.C.5
  • 12
    • 28044454537 scopus 로고    scopus 로고
    • The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion
    • Lebrun M, Michelin A, El Hajj H, Poncet J, Bradley PJ, et al. (2005) The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion. Cell Microbiol 7: 1823-1833.
    • (2005) Cell Microbiol , vol.7 , pp. 1823-1833
    • Lebrun, M.1    Michelin, A.2    El Hajj, H.3    Poncet, J.4    Bradley, P.J.5
  • 13
    • 62149116563 scopus 로고    scopus 로고
    • Novel components of the Apicomplexan moving junction reveal conserved and coccidia-restricted elements
    • Straub KW, Cheng SJ, Sohn CS, Bradley PJ, (2009) Novel components of the Apicomplexan moving junction reveal conserved and coccidia-restricted elements. Cell Microbiol 11: 590-603.
    • (2009) Cell Microbiol , vol.11 , pp. 590-603
    • Straub, K.W.1    Cheng, S.J.2    Sohn, C.S.3    Bradley, P.J.4
  • 14
    • 60349121591 scopus 로고    scopus 로고
    • Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion
    • Besteiro S, Michelin A, Poncet J, Dubremetz JF, Lebrun M, (2009) Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion. PLoS Pathog 5: e1000309.
    • (2009) PLoS Pathog , vol.5
    • Besteiro, S.1    Michelin, A.2    Poncet, J.3    Dubremetz, J.F.4    Lebrun, M.5
  • 15
    • 61849132162 scopus 로고    scopus 로고
    • Host cell entry by apicomplexa parasites requires actin polymerization in the host cell
    • Gonzalez V, Combe A, David V, Malmquist NA, Delorme V, et al. (2009) Host cell entry by apicomplexa parasites requires actin polymerization in the host cell. Cell Host Microbe 5: 259-272.
    • (2009) Cell Host Microbe , vol.5 , pp. 259-272
    • Gonzalez, V.1    Combe, A.2    David, V.3    Malmquist, N.A.4    Delorme, V.5
  • 16
    • 0033397899 scopus 로고    scopus 로고
    • Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring
    • Mordue DG, Desai N, Dustin M, Sibley LD, (1999) Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring. J Exp Med 190: 1783-1792.
    • (1999) J Exp Med , vol.190 , pp. 1783-1792
    • Mordue, D.G.1    Desai, N.2    Dustin, M.3    Sibley, L.D.4
  • 17
    • 33746267433 scopus 로고    scopus 로고
    • Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii
    • Alexander DL, Arastu-Kapur S, Dubremetz JF, Boothroyd JC, (2006) Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii. Eukaryot Cell 5: 1169-1173.
    • (2006) Eukaryot Cell , vol.5 , pp. 1169-1173
    • Alexander, D.L.1    Arastu-Kapur, S.2    Dubremetz, J.F.3    Boothroyd, J.C.4
  • 18
    • 79952231758 scopus 로고    scopus 로고
    • The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites
    • Lamarque M, Besteiro S, Papoin J, Roques M, Vulliez-Le Normand B, et al. (2011) The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites. PLoS Pathog 7: e1001276.
    • (2011) PLoS Pathog , vol.7
    • Lamarque, M.1    Besteiro, S.2    Papoin, J.3    Roques, M.4    Vulliez-Le Normand, B.5
  • 19
    • 79952234824 scopus 로고    scopus 로고
    • The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex
    • Tyler JS, Boothroyd JC, (2011) The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex. PLoS Pathog 7: e1001282.
    • (2011) PLoS Pathog , vol.7
    • Tyler, J.S.1    Boothroyd, J.C.2
  • 20
    • 79960668340 scopus 로고    scopus 로고
    • Host cell invasion by apicomplexan parasites: insights from the co-structure of AMA1 with a RON2 peptide
    • Tonkin ML, Roques M, Lamarque MH, Pugniere M, Douguet D, et al. (2011) Host cell invasion by apicomplexan parasites: insights from the co-structure of AMA1 with a RON2 peptide. Science 333: 463-467.
    • (2011) Science , vol.333 , pp. 463-467
    • Tonkin, M.L.1    Roques, M.2    Lamarque, M.H.3    Pugniere, M.4    Douguet, D.5
  • 21
    • 80051964398 scopus 로고    scopus 로고
    • Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion
    • Srinivasan P, Beatty WL, Diouf A, Herrera R, Ambroggio X, et al. (2011) Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion. Proc Natl Acad Sci U S A 108: 13275-13280.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13275-13280
    • Srinivasan, P.1    Beatty, W.L.2    Diouf, A.3    Herrera, R.4    Ambroggio, X.5
  • 23
    • 83655164555 scopus 로고    scopus 로고
    • Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa
    • Giovannini D, Spath S, Lacroix C, Perazzi A, Bargieri D, et al. (2011) Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa. Cell Host Microbe 10: 591-602.
    • (2011) Cell Host Microbe , vol.10 , pp. 591-602
    • Giovannini, D.1    Spath, S.2    Lacroix, C.3    Perazzi, A.4    Bargieri, D.5
  • 24
    • 84892638781 scopus 로고    scopus 로고
    • Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion
    • Bargieri DY, Andenmatten N, Lagal V, Thiberge S, Whitelaw JA, et al. (2013) Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion. Nat Commun 4: 2552.
    • (2013) Nat Commun , vol.4 , pp. 2552
    • Bargieri, D.Y.1    Andenmatten, N.2    Lagal, V.3    Thiberge, S.4    Whitelaw, J.A.5
  • 25
    • 79953287282 scopus 로고    scopus 로고
    • The moving junction protein RON8 facilitates firm attachment and host cell invasion in Toxoplasma gondii
    • Straub KW, Peng ED, Hajagos BE, Tyler JS, Bradley PJ, (2011) The moving junction protein RON8 facilitates firm attachment and host cell invasion in Toxoplasma gondii. PLoS Pathog 7: e1002007.
    • (2011) PLoS Pathog , vol.7
    • Straub, K.W.1    Peng, E.D.2    Hajagos, B.E.3    Tyler, J.S.4    Bradley, P.J.5
  • 26
    • 0034881397 scopus 로고    scopus 로고
    • The pro region of Toxoplasma ROP1 is a rhoptry-targeting signal
    • Bradley PJ, Boothroyd JC, (2001) The pro region of Toxoplasma ROP1 is a rhoptry-targeting signal. Int J Parasitol 31: 1177-1186.
    • (2001) Int J Parasitol , vol.31 , pp. 1177-1186
    • Bradley, P.J.1    Boothroyd, J.C.2
  • 28
    • 84855964433 scopus 로고    scopus 로고
    • Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1
    • Hajagos BE, Turetzky JM, Peng ED, Cheng SJ, Ryan CM, et al. (2012) Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1. Traffic 13: 292-304.
    • (2012) Traffic , vol.13 , pp. 292-304
    • Hajagos, B.E.1    Turetzky, J.M.2    Peng, E.D.3    Cheng, S.J.4    Ryan, C.M.5
  • 29
    • 79251579940 scopus 로고    scopus 로고
    • Microbiology. A tail of division
    • Cowman AF, Tonkin CJ, (2011) Microbiology. A tail of division. Science 331: 409-410.
    • (2011) Science , vol.331 , pp. 409-410
    • Cowman, A.F.1    Tonkin, C.J.2
  • 30
    • 6344294832 scopus 로고    scopus 로고
    • The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells
    • Carey KL, Jongco AM, Kim K, Ward GE, (2004) The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells. Eukaryot Cell 3: 1320-1330.
    • (2004) Eukaryot Cell , vol.3 , pp. 1320-1330
    • Carey, K.L.1    Jongco, A.M.2    Kim, K.3    Ward, G.E.4
  • 31
    • 79955948463 scopus 로고    scopus 로고
    • The moving junction of apicomplexan parasites: a key structure for invasion
    • Besteiro S, Dubremetz JF, Lebrun M, (2011) The moving junction of apicomplexan parasites: a key structure for invasion. Cell Microbiol 13: 797-805.
    • (2011) Cell Microbiol , vol.13 , pp. 797-805
    • Besteiro, S.1    Dubremetz, J.F.2    Lebrun, M.3
  • 32
    • 77957874167 scopus 로고    scopus 로고
    • Coordinated progression through two subtranscriptomes underlies the tachyzoite cycle of Toxoplasma gondii
    • Behnke MS, Wootton JC, Lehmann MM, Radke JB, Lucas O, et al. (2010) Coordinated progression through two subtranscriptomes underlies the tachyzoite cycle of Toxoplasma gondii. PLoS One 5: e12354.
    • (2010) PLoS One , vol.5
    • Behnke, M.S.1    Wootton, J.C.2    Lehmann, M.M.3    Radke, J.B.4    Lucas, O.5
  • 33
    • 84874775116 scopus 로고    scopus 로고
    • A Toxoplasma Palmitoyl Acyl Transferase and the Palmitoylated Armadillo Repeat Protein TgARO Govern Apical Rhoptry Tethering and Reveal a Critical Role for the Rhoptries in Host Cell Invasion but Not Egress
    • Beck JR, Fung C, Straub KW, Coppens I, Vashisht AA, et al. (2013) A Toxoplasma Palmitoyl Acyl Transferase and the Palmitoylated Armadillo Repeat Protein TgARO Govern Apical Rhoptry Tethering and Reveal a Critical Role for the Rhoptries in Host Cell Invasion but Not Egress. PLoS Pathog 9: e1003162.
    • (2013) PLoS Pathog , vol.9
    • Beck, J.R.1    Fung, C.2    Straub, K.W.3    Coppens, I.4    Vashisht, A.A.5
  • 34
    • 0029869791 scopus 로고    scopus 로고
    • Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite
    • Dobrowolski JM, Sibley LD, (1996) Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite. Cell 84: 933-939.
    • (1996) Cell , vol.84 , pp. 933-939
    • Dobrowolski, J.M.1    Sibley, L.D.2
  • 35
    • 84867751254 scopus 로고    scopus 로고
    • Modulation of innate immunity by Toxoplasma gondii virulence effectors
    • Hunter CA, Sibley LD, (2012) Modulation of innate immunity by Toxoplasma gondii virulence effectors. Nat Rev Microbiol 10: 766-778.
    • (2012) Nat Rev Microbiol , vol.10 , pp. 766-778
    • Hunter, C.A.1    Sibley, L.D.2
  • 36
    • 0035875917 scopus 로고    scopus 로고
    • Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole
    • Hakansson S, Charron AJ, Sibley LD, (2001) Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole. Embo J 20: 3132-3144.
    • (2001) Embo J , vol.20 , pp. 3132-3144
    • Hakansson, S.1    Charron, A.J.2    Sibley, L.D.3
  • 37
    • 0036606239 scopus 로고    scopus 로고
    • Is Toxoplasma egress the first step in invasion?
    • Hoff EF, Carruthers VB, (2002) Is Toxoplasma egress the first step in invasion? Trends Parasitol 18: 251-255.
    • (2002) Trends Parasitol , vol.18 , pp. 251-255
    • Hoff, E.F.1    Carruthers, V.B.2
  • 38
    • 84875179761 scopus 로고    scopus 로고
    • The Toxoplasma protein ARO mediates the apical positioning of rhoptry organelles, a prerequisite for host cell invasion
    • Mueller C, Klages N, Jacot D, Santos JM, Cabrera A, et al. (2013) The Toxoplasma protein ARO mediates the apical positioning of rhoptry organelles, a prerequisite for host cell invasion. Cell Host Microbe 13: 289-301.
    • (2013) Cell Host Microbe , vol.13 , pp. 289-301
    • Mueller, C.1    Klages, N.2    Jacot, D.3    Santos, J.M.4    Cabrera, A.5
  • 39
    • 0036861640 scopus 로고    scopus 로고
    • Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole
    • Bradley PJ, Hsieh CL, Boothroyd JC, (2002) Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole. Mol Biochem Parasitol 125: 189-193.
    • (2002) Mol Biochem Parasitol , vol.125 , pp. 189-193
    • Bradley, P.J.1    Hsieh, C.L.2    Boothroyd, J.C.3
  • 40
    • 84858057938 scopus 로고    scopus 로고
    • Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii
    • Lamarque MH, Papoin J, Finizio AL, Lentini G, Pfaff AW, et al. (2012) Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii. PLoS One 7: e32457.
    • (2012) PLoS One , vol.7
    • Lamarque, M.H.1    Papoin, J.2    Finizio, A.L.3    Lentini, G.4    Pfaff, A.W.5
  • 41
    • 0017879439 scopus 로고
    • Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite
    • Aikawa M, Miller LH, Johnson J, Rabbege J, (1978) Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite. J Cell Biol 77: 72-82.
    • (1978) J Cell Biol , vol.77 , pp. 72-82
    • Aikawa, M.1    Miller, L.H.2    Johnson, J.3    Rabbege, J.4
  • 42
    • 56749176947 scopus 로고    scopus 로고
    • One step at a time: endoplasmic reticulum-associated degradation
    • Vembar SS, Brodsky JL, (2008) One step at a time: endoplasmic reticulum-associated degradation. Nat Rev Mol Cell Biol 9: 944-957.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 944-957
    • Vembar, S.S.1    Brodsky, J.L.2
  • 43
    • 70450251981 scopus 로고    scopus 로고
    • Genetic evidence that an endosymbiont-derived endoplasmic reticulum-associated protein degradation (ERAD) system functions in import of apicoplast proteins
    • Agrawal S, van Dooren GG, Beatty WL, Striepen B, (2009) Genetic evidence that an endosymbiont-derived endoplasmic reticulum-associated protein degradation (ERAD) system functions in import of apicoplast proteins. J Biol Chem 284: 33683-33691.
    • (2009) J Biol Chem , vol.284 , pp. 33683-33691
    • Agrawal, S.1    van Dooren, G.G.2    Beatty, W.L.3    Striepen, B.4
  • 44
    • 63449134429 scopus 로고    scopus 로고
    • Identification of rhoptry trafficking determinants and evidence for a novel sorting mechanism in the malaria parasite Plasmodium falciparum
    • Richard D, Kats LM, Langer C, Black CG, Mitri K, et al. (2009) Identification of rhoptry trafficking determinants and evidence for a novel sorting mechanism in the malaria parasite Plasmodium falciparum. PLoS Pathog 5: e1000328.
    • (2009) PLoS Pathog , vol.5
    • Richard, D.1    Kats, L.M.2    Langer, C.3    Black, C.G.4    Mitri, K.5
  • 45
    • 0035809213 scopus 로고    scopus 로고
    • Identification and characterization of an escorter for two secretory adhesins in Toxoplasma gondii
    • Reiss M, Viebig N, Brecht S, Fourmaux MN, Soete M, et al. (2001) Identification and characterization of an escorter for two secretory adhesins in Toxoplasma gondii. J Cell Biol 152: 563-578.
    • (2001) J Cell Biol , vol.152 , pp. 563-578
    • Reiss, M.1    Viebig, N.2    Brecht, S.3    Fourmaux, M.N.4    Soete, M.5
  • 46
    • 33748066307 scopus 로고    scopus 로고
    • Toxoplasma MIC2 is a major determinant of invasion and virulence
    • Huynh MH, Carruthers VB, (2006) Toxoplasma MIC2 is a major determinant of invasion and virulence. PLoS Pathog 2: e84.
    • (2006) PLoS Pathog , vol.2
    • Huynh, M.H.1    Carruthers, V.B.2
  • 47
  • 48
    • 0029895115 scopus 로고    scopus 로고
    • Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation
    • Donald RG, Carter D, Ullman B, Roos DS, (1996) Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation. J Biol Chem 271: 14010-14019.
    • (1996) J Biol Chem , vol.271 , pp. 14010-14019
    • Donald, R.G.1    Carter, D.2    Ullman, B.3    Roos, D.S.4
  • 49
    • 0026033705 scopus 로고
    • Characterization of the protein contents of rhoptries and dense granules of Toxoplasma gondii tachyzoites by subcellular fractionation and monoclonal antibodies
    • Leriche MA, Dubremetz JF, (1991) Characterization of the protein contents of rhoptries and dense granules of Toxoplasma gondii tachyzoites by subcellular fractionation and monoclonal antibodies. Mol Biochem Parasitol 45: 249-259.
    • (1991) Mol Biochem Parasitol , vol.45 , pp. 249-259
    • Leriche, M.A.1    Dubremetz, J.F.2
  • 50
    • 77953915276 scopus 로고    scopus 로고
    • Processing and secretion of ROP13: A unique Toxoplasma effector protein
    • Turetzky JM, Chu DK, Hajagos BE, Bradley PJ, (2010) Processing and secretion of ROP13: A unique Toxoplasma effector protein. Int J Parasitol 40: 1037-1044.
    • (2010) Int J Parasitol , vol.40 , pp. 1037-1044
    • Turetzky, J.M.1    Chu, D.K.2    Hajagos, B.E.3    Bradley, P.J.4
  • 51
    • 0023737790 scopus 로고
    • Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii
    • Burg JL, Perelman D, Kasper LH, Ware PL, Boothroyd JC, (1988) Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. J Immunol 141: 3584-3591.
    • (1988) J Immunol , vol.141 , pp. 3584-3591
    • Burg, J.L.1    Perelman, D.2    Kasper, L.H.3    Ware, P.L.4    Boothroyd, J.C.5
  • 52
    • 78149330647 scopus 로고    scopus 로고
    • A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division
    • Beck JR, Rodriguez-Fernandez IA, Cruz de Leon J, Huynh MH, Carruthers VB, et al. (2010) A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division. PLoS Pathog 6: e1001094.
    • (2010) PLoS Pathog , vol.6
    • Beck, J.R.1    Rodriguez-Fernandez, I.A.2    Cruz de Leon, J.3    Huynh, M.H.4    Carruthers, V.B.5
  • 53
    • 26644451857 scopus 로고    scopus 로고
    • Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii
    • Bradley PJ, Ward C, Cheng SJ, Alexander DL, Coller S, et al. (2005) Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. J Biol Chem 280: 34245-34258.
    • (2005) J Biol Chem , vol.280 , pp. 34245-34258
    • Bradley, P.J.1    Ward, C.2    Cheng, S.J.3    Alexander, D.L.4    Coller, S.5
  • 54
    • 80055104493 scopus 로고    scopus 로고
    • A GCN2-like eukaryotic initiation factor 2 kinase increases the viability of extracellular Toxoplasma gondii parasites
    • Konrad C, Wek RC, Sullivan WJ Jr, (2011) A GCN2-like eukaryotic initiation factor 2 kinase increases the viability of extracellular Toxoplasma gondii parasites. Eukaryot Cell 10: 1403-1412.
    • (2011) Eukaryot Cell , vol.10 , pp. 1403-1412
    • Konrad, C.1    Wek, R.C.2    Sullivan Jr., W.J.3
  • 55
    • 64749102772 scopus 로고    scopus 로고
    • Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80
    • Huynh MH, Carruthers VB, (2009) Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80. Eukaryot Cell 8: 530-539.
    • (2009) Eukaryot Cell , vol.8 , pp. 530-539
    • Huynh, M.H.1    Carruthers, V.B.2
  • 56
    • 84855323196 scopus 로고    scopus 로고
    • A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor
    • Sheiner L, Demerly JL, Poulsen N, Beatty WL, Lucas O, et al. (2011) A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor. PLoS Pathog 7: e1002392.
    • (2011) PLoS Pathog , vol.7
    • Sheiner, L.1    Demerly, J.L.2    Poulsen, N.3    Beatty, W.L.4    Lucas, O.5
  • 58
    • 0029050555 scopus 로고
    • Insertional mutagenesis and marker rescue in a protozoan parasite: cloning of the uracil phosphoribosyltransferase locus from Toxoplasma gondii
    • Donald RG, Roos DS, (1995) Insertional mutagenesis and marker rescue in a protozoan parasite: cloning of the uracil phosphoribosyltransferase locus from Toxoplasma gondii. Proc Natl Acad Sci U S A 92: 5749-5753.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5749-5753
    • Donald, R.G.1    Roos, D.S.2
  • 59
    • 0038558167 scopus 로고    scopus 로고
    • Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex
    • Huynh MH, Rabenau KE, Harper JM, Beatty WL, Sibley LD, et al. (2003) Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex. Embo J 22: 2082-2090.
    • (2003) Embo J , vol.22 , pp. 2082-2090
    • Huynh, M.H.1    Rabenau, K.E.2    Harper, J.M.3    Beatty, W.L.4    Sibley, L.D.5
  • 61
    • 24344439282 scopus 로고    scopus 로고
    • Conditional expression of Toxoplasma gondii apical membrane antigen-1 (TgAMA1) demonstrates that TgAMA1 plays a critical role in host cell invasion
    • Mital J, Meissner M, Soldati D, Ward GE, (2005) Conditional expression of Toxoplasma gondii apical membrane antigen-1 (TgAMA1) demonstrates that TgAMA1 plays a critical role in host cell invasion. Mol Biol Cell 16: 4341-4349.
    • (2005) Mol Biol Cell , vol.16 , pp. 4341-4349
    • Mital, J.1    Meissner, M.2    Soldati, D.3    Ward, G.E.4
  • 62
    • 0034458967 scopus 로고    scopus 로고
    • Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress
    • Black MW, Arrizabalaga G, Boothroyd JC, (2000) Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress. Mol Cell Biol 20: 9399-9408.
    • (2000) Mol Cell Biol , vol.20 , pp. 9399-9408
    • Black, M.W.1    Arrizabalaga, G.2    Boothroyd, J.C.3
  • 63
    • 84856697951 scopus 로고    scopus 로고
    • MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy
    • Liu PT, Wheelwright M, Teles R, Komisopoulou E, Edfeldt K, et al. (2012) MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nat Med 18: 267-273.
    • (2012) Nat Med , vol.18 , pp. 267-273
    • Liu, P.T.1    Wheelwright, M.2    Teles, R.3    Komisopoulou, E.4    Edfeldt, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.