메뉴 건너뛰기




Volumn 50, Issue 7, 2014, Pages 1321-1329

Controversies in renal cell carcinoma: Treatment choice after progression on vascular endothelial growth factor-targeted therapy

Author keywords

Quality of life; Renal cell carcinoma; Second line; Sequencing; Treatment planning

Indexed keywords

AXITINIB; BEVACIZUMAB; EVEROLIMUS; INTERFERON; PAZOPANIB; PLACEBO; PROTEIN TYROSINE KINASE INHIBITOR; SORAFENIB; SUNITINIB; TEMSIROLIMUS; VASCULOTROPIN;

EID: 84897431648     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.02.007     Document Type: Review
Times cited : (30)

References (56)
  • 1
    • 68949145218 scopus 로고    scopus 로고
    • Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
    • R.J. Motzer, T.E. Hutson, P. Tomczak, M.D. Michaelson, R.M. Bukowski, and S. Oudard et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma J Clin Oncol 27 2009 3584 3590
    • (2009) J Clin Oncol , vol.27 , pp. 3584-3590
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3    Michaelson, M.D.4    Bukowski, R.M.5    Oudard, S.6
  • 2
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
    • C.N. Sternberg, I.D. Davis, J. Mardiak, C. Szczylik, E. Lee, and J. Wagstaff et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial J Clin Oncol 28 2010 1061 1068
    • (2010) J Clin Oncol , vol.28 , pp. 1061-1068
    • Sternberg, C.N.1    Davis, I.D.2    Mardiak, J.3    Szczylik, C.4    Lee, E.5    Wagstaff, J.6
  • 3
    • 56749161699 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206
    • B.I. Rini, S. Halabi, J.E. Rosenberg, W.M. Stadler, D.A. Vaena, and S.S. Ou et al. Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206 J Clin Oncol 26 2008 5422 5428
    • (2008) J Clin Oncol , vol.26 , pp. 5422-5428
    • Rini, B.I.1    Halabi, S.2    Rosenberg, J.E.3    Stadler, W.M.4    Vaena, D.A.5    Ou, S.S.6
  • 5
    • 84866594008 scopus 로고    scopus 로고
    • Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • B. Escudier, T. Eisen, C. Porta, J.J. Patard, V. Khoo, and F. Algaba et al. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Ann Oncol 23 Suppl. 7 2012 vii65 vii71
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 7
    • Escudier, B.1    Eisen, T.2    Porta, C.3    Patard, J.J.4    Khoo, V.5    Algaba, F.6
  • 7
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • G. Hudes, M. Carducci, P. Tomczak, J. Dutcher, R. Figlin, and A. Kapoor et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma N Engl J Med 356 2007 2271 2281
    • (2007) N Engl J Med , vol.356 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3    Dutcher, J.4    Figlin, R.5    Kapoor, A.6
  • 8
    • 84876685070 scopus 로고    scopus 로고
    • Second line treatment of metastatic renal cell carcinoma: The Institut Gustave Roussy experience with targeted therapies in 251 consecutive patients
    • A. Levy, J. Menard, L. Albiges, Y. Loriot, M. Di Palma, and K. Fizazi et al. Second line treatment of metastatic renal cell carcinoma: the Institut Gustave Roussy experience with targeted therapies in 251 consecutive patients Eur J Cancer 49 2013 1898 1904
    • (2013) Eur J Cancer , vol.49 , pp. 1898-1904
    • Levy, A.1    Menard, J.2    Albiges, L.3    Loriot, Y.4    Di Palma, M.5    Fizazi, K.6
  • 9
    • 77956227464 scopus 로고    scopus 로고
    • Phase 3 trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors
    • R.J. Motzer, B. Escudier, S. Oudard, T.E. Hutson, C. Porta, and S. Bracarda et al. Phase 3 trial of everolimus for metastatic renal cell carcinoma: final results and analysis of prognostic factors Cancer 116 2010 4256 4265
    • (2010) Cancer , vol.116 , pp. 4256-4265
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3    Hutson, T.E.4    Porta, C.5    Bracarda, S.6
  • 10
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
    • R.J. Motzer, B. Escudier, S. Oudard, T.E. Hutson, C. Porta, and S. Bracarda et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial Lancet 372 2008 449 456
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3    Hutson, T.E.4    Porta, C.5    Bracarda, S.6
  • 11
    • 82755183572 scopus 로고    scopus 로고
    • Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
    • B.I. Rini, B. Escudier, P. Tomczak, A. Kaprin, C. Szczylik, and T.E. Hutson et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial Lancet 378 2011 1931 1939
    • (2011) Lancet , vol.378 , pp. 1931-1939
    • Rini, B.I.1    Escudier, B.2    Tomczak, P.3    Kaprin, A.4    Szczylik, C.5    Hutson, T.E.6
  • 12
    • 84876974877 scopus 로고    scopus 로고
    • Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: Overall survival analysis and updated results from a randomised phase 3 trial
    • R.J. Motzer, B. Escudier, P. Tomczak, T.E. Hutson, M.D. Michaelson, and S. Negrier et al. Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial Lancet Oncol 14 2013 552 562
    • (2013) Lancet Oncol , vol.14 , pp. 552-562
    • Motzer, R.J.1    Escudier, B.2    Tomczak, P.3    Hutson, T.E.4    Michaelson, M.D.5    Negrier, S.6
  • 13
    • 84888004552 scopus 로고    scopus 로고
    • "real world" treatment of metastatic renal cell carcinoma in a joint community-academic cohort: Progression-free survival over three lines of therapy
    • M.R. Harrison, D.J. George, M.S. Walker, C. Chen, B. Korytowsky, and D.T. Kirkendall et al. "Real world" treatment of metastatic renal cell carcinoma in a joint community-academic cohort: progression-free survival over three lines of therapy Clin Genitourin Cancer 11 2013 441 450
    • (2013) Clin Genitourin Cancer , vol.11 , pp. 441-450
    • Harrison, M.R.1    George, D.J.2    Walker, M.S.3    Chen, C.4    Korytowsky, B.5    Kirkendall, D.T.6
  • 14
    • 84884902024 scopus 로고    scopus 로고
    • Outcomes of patients with metastatic clear-cell renal cell carcinoma treated with pazopanib after disease progression with other targeted therapies
    • M.R. Matrana, C. Duran, A. Shetty, L. Xiao, B.J. Atkinson, and P. Corn et al. Outcomes of patients with metastatic clear-cell renal cell carcinoma treated with pazopanib after disease progression with other targeted therapies Eur J Cancer 49 2013 3169 3175
    • (2013) Eur J Cancer , vol.49 , pp. 3169-3175
    • Matrana, M.R.1    Duran, C.2    Shetty, A.3    Xiao, L.4    Atkinson, B.J.5    Corn, P.6
  • 15
    • 84890905069 scopus 로고    scopus 로고
    • Pazopanib after sunitinib failure in patients with metastatic renal cell carcinoma
    • J. Rautiola, T. Utriainen, K. Peltola, H. Joensuu, and P. Bono Pazopanib after sunitinib failure in patients with metastatic renal cell carcinoma Acta Oncol 53 2014 113 118
    • (2014) Acta Oncol , vol.53 , pp. 113-118
    • Rautiola, J.1    Utriainen, T.2    Peltola, K.3    Joensuu, H.4    Bono, P.5
  • 16
    • 84883453765 scopus 로고    scopus 로고
    • Pazopanib as second-line treatment after sunitinib or bevacizumab in patients with advanced renal cell carcinoma: A Sarah Cannon Oncology Research Consortium Phase II trial
    • J.D. Hainsworth, M.S. Rubin, E.R. Arrowsmith, J. Khatcheressian, E.J. Crane, and L.A. Franco Pazopanib as second-line treatment after sunitinib or bevacizumab in patients with advanced renal cell carcinoma: A Sarah Cannon Oncology Research Consortium Phase II trial Clin Genitourin Cancer 11 2013 270 275
    • (2013) Clin Genitourin Cancer , vol.11 , pp. 270-275
    • Hainsworth, J.D.1    Rubin, M.S.2    Arrowsmith, E.R.3    Khatcheressian, J.4    Crane, E.J.5    Franco, L.A.6
  • 17
    • 84880267774 scopus 로고    scopus 로고
    • Comparative efficacy of vascular endothelial growth factor (VEGF) tyrosine kinase inhibitor (TKI) and mammalian target of rapamycin (mTOR) inhibitor as second-line therapy in patients with metastatic renal cell carcinoma after the failure of first-line VEGF TKI
    • K. Park, J.L. Lee, I. Park, S. Park, Y. Ahn, and J.H. Ahn et al. Comparative efficacy of vascular endothelial growth factor (VEGF) tyrosine kinase inhibitor (TKI) and mammalian target of rapamycin (mTOR) inhibitor as second-line therapy in patients with metastatic renal cell carcinoma after the failure of first-line VEGF TKI Med Oncol 29 2012 3291 3297
    • (2012) Med Oncol , vol.29 , pp. 3291-3297
    • Park, K.1    Lee, J.L.2    Park, I.3    Park, S.4    Ahn, Y.5    Ahn, J.H.6
  • 18
    • 84872811400 scopus 로고    scopus 로고
    • Sequential use of sorafenib and sunitinib in advanced renal cell carcinoma: Does the order of sequencing matter?
    • N. Calvani, F. Morelli, S. Leo, L. Orlando, L. Lombardi, and A. Gnoni et al. Sequential use of sorafenib and sunitinib in advanced renal cell carcinoma: does the order of sequencing matter? Med Oncol 29 2012 1908 1913
    • (2012) Med Oncol , vol.29 , pp. 1908-1913
    • Calvani, N.1    Morelli, F.2    Leo, S.3    Orlando, L.4    Lombardi, L.5    Gnoni, A.6
  • 19
    • 79959782949 scopus 로고    scopus 로고
    • Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): An Italian multicentre retrospective analysis of 189 patient cases
    • C. Porta, G. Procopio, G. Carteni, R. Sabbatini, A. Bearz, and I. Chiappino et al. Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): an Italian multicentre retrospective analysis of 189 patient cases BJU Int 108 2011 E250 E257
    • (2011) BJU Int , vol.108
    • Porta, C.1    Procopio, G.2    Carteni, G.3    Sabbatini, R.4    Bearz, A.5    Chiappino, I.6
  • 20
    • 73749087933 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with sunitinib-refractory metastatic renal cell cancer
    • G. Di Lorenzo, G. Carteni, R. Autorino, G. Bruni, M. Tudini, and M. Rizzo et al. Phase II study of sorafenib in patients with sunitinib-refractory metastatic renal cell cancer J Clin Oncol 27 2009 4469 4474
    • (2009) J Clin Oncol , vol.27 , pp. 4469-4474
    • Di Lorenzo, G.1    Carteni, G.2    Autorino, R.3    Bruni, G.4    Tudini, M.5    Rizzo, M.6
  • 21
    • 58949092548 scopus 로고    scopus 로고
    • Sequential therapy with sorafenib and sunitinib in renal cell carcinoma
    • A.Z. Dudek, J. Zolnierek, A. Dham, B.R. Lindgren, and C. Szczylik Sequential therapy with sorafenib and sunitinib in renal cell carcinoma Cancer 115 2009 61 67
    • (2009) Cancer , vol.115 , pp. 61-67
    • Dudek, A.Z.1    Zolnierek, J.2    Dham, A.3    Lindgren, B.R.4    Szczylik, C.5
  • 22
    • 80255141916 scopus 로고    scopus 로고
    • Sequence therapy in patients with metastatic renal cell carcinoma: Comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors
    • J. Busch, C. Seidel, C. Kempkensteffen, M. Johannsen, I. Wolff, and S. Hinz et al. Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors Eur Urol 60 2011 1163 1170
    • (2011) Eur Urol , vol.60 , pp. 1163-1170
    • Busch, J.1    Seidel, C.2    Kempkensteffen, C.3    Johannsen, M.4    Wolff, I.5    Hinz, S.6
  • 23
    • 77955895649 scopus 로고    scopus 로고
    • Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab
    • J.A. Garcia, T.E. Hutson, P. Elson, C.L. Cowey, T. Gilligan, and C. Nemec et al. Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab Cancer 116 2010 5383 5390
    • (2010) Cancer , vol.116 , pp. 5383-5390
    • Garcia, J.A.1    Hutson, T.E.2    Elson, P.3    Cowey, C.L.4    Gilligan, T.5    Nemec, C.6
  • 24
    • 84875126397 scopus 로고    scopus 로고
    • Everolimus in metastatic renal cell carcinoma after failure of initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor (VEGFr-TKI) therapy: Results of an interim analysis of a non-interventional study
    • L. Bergmann, P.J. Goebell, U. Kube, M. Kindler, E. Herrmann, and J. Janssen et al. Everolimus in metastatic renal cell carcinoma after failure of initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor (VEGFr-TKI) therapy: results of an interim analysis of a non-interventional study Onkologie 36 2013 95 100
    • (2013) Onkologie , vol.36 , pp. 95-100
    • Bergmann, L.1    Goebell, P.J.2    Kube, U.3    Kindler, M.4    Herrmann, E.5    Janssen, J.6
  • 25
    • 84868515033 scopus 로고    scopus 로고
    • Second-line treatment outcomes after first-line sunitinib therapy in metastatic renal cell carcinoma
    • C.C. Chen, G.P. Hess, Z. Liu, D.H. Gesme, S.S. Agarwala, and C.C. Garay et al. Second-line treatment outcomes after first-line sunitinib therapy in metastatic renal cell carcinoma Clin Genitourin Cancer 10 2012 256 261
    • (2012) Clin Genitourin Cancer , vol.10 , pp. 256-261
    • Chen, C.C.1    Hess, G.P.2    Liu, Z.3    Gesme, D.H.4    Agarwala, S.S.5    Garay, C.C.6
  • 26
    • 84877703634 scopus 로고    scopus 로고
    • Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort
    • Iacovelli R, Carteni G, Sternberg CN, Milella M, Santoni M, Di Lorenzo G, et al. Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort. Eur J Cancer 2013;49:2134-42.
    • (2013) Eur J Cancer , vol.49 , pp. 2134-2142
    • Iacovelli, R.1    Carteni, G.2    Sternberg, C.N.3    Milella, M.4    Santoni, M.5    Di Lorenzo, G.6
  • 27
    • 84892186780 scopus 로고    scopus 로고
    • Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after suninitib in patients with metastatic renal cell carcinoma
    • Dec 2. [Epub before print]
    • Hutson T, Escudier B, Esteban E, Bjarnason GA, Lim HY, Pittman K, et al. Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after suninitib in patients with metastatic renal cell carcinoma. J Clin Oncol 2013 Dec 2. [Epub before print].
    • (2013) J Clin Oncol
    • Hutson, T.1    Escudier, B.2    Esteban, E.3    Bjarnason, G.A.4    Lim, H.Y.5    Pittman, K.6
  • 28
    • 84856211584 scopus 로고    scopus 로고
    • Everolimus in metastatic renal cell carcinoma: Subgroup analysis of patients with 1 or 2 previous vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapies enrolled in the phase III RECORD-1 study
    • E. Calvo, B. Escudier, R.J. Motzer, S. Oudard, T.E. Hutson, and C. Porta et al. Everolimus in metastatic renal cell carcinoma: Subgroup analysis of patients with 1 or 2 previous vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapies enrolled in the phase III RECORD-1 study Eur J Cancer 48 2012 333 339
    • (2012) Eur J Cancer , vol.48 , pp. 333-339
    • Calvo, E.1    Escudier, B.2    Motzer, R.J.3    Oudard, S.4    Hutson, T.E.5    Porta, C.6
  • 29
    • 70449718833 scopus 로고    scopus 로고
    • Quality of life in patients with metastatic renal cell carcinoma: The importance of patient-reported outcomes
    • D. Cella Quality of life in patients with metastatic renal cell carcinoma: the importance of patient-reported outcomes Cancer Treat Rev 35 2009 733 737
    • (2009) Cancer Treat Rev , vol.35 , pp. 733-737
    • Cella, D.1
  • 30
    • 42649145828 scopus 로고    scopus 로고
    • Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): A literature review
    • K. Gupta, J.D. Miller, J.Z. Li, M.W. Russell, and C. Charbonneau Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review Cancer Treat Rev 34 2008 193 205
    • (2008) Cancer Treat Rev , vol.34 , pp. 193-205
    • Gupta, K.1    Miller, J.D.2    Li, J.Z.3    Russell, M.W.4    Charbonneau, C.5
  • 31
    • 36849029456 scopus 로고    scopus 로고
    • Patient-reported outcomes in phase II cancer clinical trials: Lessons learned and future directions
    • L.I. Wagner, L. Wenzel, E. Shaw, and D. Cella Patient-reported outcomes in phase II cancer clinical trials: lessons learned and future directions J Clin Oncol 25 2007 5058 5062
    • (2007) J Clin Oncol , vol.25 , pp. 5058-5062
    • Wagner, L.I.1    Wenzel, L.2    Shaw, E.3    Cella, D.4
  • 32
    • 84865506371 scopus 로고    scopus 로고
    • Patient preference between pazopanib (Paz) and sunitinib (Sun): Results of a randomized double-blind, placebo-controlled, cross-over study in patients with metastatic renal cell carcinoma (mRCC) - PISCES study, NCT 01064310
    • JUNE
    • B.J. Escudier, C. Porta, P. Bono, U. De Giorgi, O. Parikh, and R.E. Hawkins et al. Patient preference between pazopanib (Paz) and sunitinib (Sun): results of a randomized double-blind, placebo-controlled, cross-over study in patients with metastatic renal cell carcinoma (mRCC) - PISCES study, NCT 01064310 J Clin Oncol 30 June 20 Supplement 2012 CRA4502
    • (2012) J Clin Oncol , vol.30 , Issue.20 , pp. 4502
    • Escudier, B.J.1    Porta, C.2    Bono, P.3    De Giorgi, U.4    Parikh, O.5    Hawkins, R.E.6
  • 33
    • 84877010240 scopus 로고    scopus 로고
    • Patient-reported outcomes for axitinib vs sorafenib in metastatic renal cell carcinoma: Phase III (AXIS) trial
    • D. Cella, B. Escudier, B. Rini, C. Chen, H. Bhattacharyya, and J. Tarazi et al. Patient-reported outcomes for axitinib vs sorafenib in metastatic renal cell carcinoma: phase III (AXIS) trial Br J Cancer 108 2013 1571 1578
    • (2013) Br J Cancer , vol.108 , pp. 1571-1578
    • Cella, D.1    Escudier, B.2    Rini, B.3    Chen, C.4    Bhattacharyya, H.5    Tarazi, J.6
  • 34
    • 84897398568 scopus 로고    scopus 로고
    • Time to deterioration (TTD) in patient-reported outcomes in phase 3 AXIS trial of axitinib vs sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC)
    • Abstract 3006
    • D. Cella, B. Escudier, B. Rini, C. Chen, H. Bhattacharyya, and J. Tarazi et al. Time to deterioration (TTD) in patient-reported outcomes in phase 3 AXIS trial of axitinib vs sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC) Eur J Cancer 47 Suppl. 1 2011 Abstract 3006
    • (2011) Eur J Cancer , vol.47 , Issue.SUPPL. 1
    • Cella, D.1    Escudier, B.2    Rini, B.3    Chen, C.4    Bhattacharyya, H.5    Tarazi, J.6
  • 35
    • 84880157519 scopus 로고    scopus 로고
    • Axitinib in metastatic renal cell carcinoma: Results of a pharmacokinetic and pharmacodynamic analysis
    • B.I. Rini, M. Garrett, B. Poland, J.P. Dutcher, O. Rixe, and G. Wilding et al. Axitinib in metastatic renal cell carcinoma: results of a pharmacokinetic and pharmacodynamic analysis J Clin Pharmacol 53 2013 491 504
    • (2013) J Clin Pharmacol , vol.53 , pp. 491-504
    • Rini, B.I.1    Garrett, M.2    Poland, B.3    Dutcher, J.P.4    Rixe, O.5    Wilding, G.6
  • 37
    • 84884279729 scopus 로고    scopus 로고
    • The association of clinical outcome to first-line VEGF-targeted therapy with clinical outcome to second-line VEGF-targeted therapy in metastatic renal cell carcinoma patients
    • M.Y. Al-Marrawi, B.I. Rini, L.C. Harshman, G. Bjarnason, L. Wood, and U. Vaishampayan et al. The association of clinical outcome to first-line VEGF-targeted therapy with clinical outcome to second-line VEGF-targeted therapy in metastatic renal cell carcinoma patients Target Oncol 8 2013 203 209
    • (2013) Target Oncol , vol.8 , pp. 203-209
    • Al-Marrawi, M.Y.1    Rini, B.I.2    Harshman, L.C.3    Bjarnason, G.4    Wood, L.5    Vaishampayan, U.6
  • 38
    • 62849099971 scopus 로고    scopus 로고
    • Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib
    • K. Zimmermann, A. Schmittel, U. Steiner, A.M. Asemissen, M. Knoedler, and E. Thiel et al. Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib Oncology 76 2009 350 354
    • (2009) Oncology , vol.76 , pp. 350-354
    • Zimmermann, K.1    Schmittel, A.2    Steiner, U.3    Asemissen, A.M.4    Knoedler, M.5    Thiel, E.6
  • 39
    • 36749064602 scopus 로고    scopus 로고
    • Antitumor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy
    • I. Tamaskar, J.A. Garcia, P. Elson, L. Wood, T. Mekhail, and R. Dreicer et al. Antitumor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy J Urol 179 2008 81 86
    • (2008) J Urol , vol.179 , pp. 81-86
    • Tamaskar, I.1    Garcia, J.A.2    Elson, P.3    Wood, L.4    Mekhail, T.5    Dreicer, R.6
  • 40
    • 77951667987 scopus 로고    scopus 로고
    • Mechanisms of resistance to antiangiogenesis therapy
    • F. Azam, S. Mehta, and A.L. Harris Mechanisms of resistance to antiangiogenesis therapy Eur J Cancer 46 2010 1323 1332
    • (2010) Eur J Cancer , vol.46 , pp. 1323-1332
    • Azam, F.1    Mehta, S.2    Harris, A.L.3
  • 41
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • G. Bergers, and D. Hanahan Modes of resistance to anti-angiogenic therapy Nat Rev Cancer 8 2008 592 603
    • (2008) Nat Rev Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 42
    • 77649134498 scopus 로고    scopus 로고
    • New strategies in kidney cancer: Therapeutic advances through understanding the molecular basis of response and resistance
    • B.I. Rini New strategies in kidney cancer: therapeutic advances through understanding the molecular basis of response and resistance Clin Cancer Res 16 2010 1348 1354
    • (2010) Clin Cancer Res , vol.16 , pp. 1348-1354
    • Rini, B.I.1
  • 43
    • 84876982983 scopus 로고    scopus 로고
    • Are tyrosine kinase inhibitors still active in patients with metastatic renal cell carcinoma previously treated with a tyrosine kinase inhibitor and everolimus? Experience of 36 patients treated in France in the RECORD-1 Trial
    • A. Blesius, B. Beuselinck, C. Chevreau, A. Ravaud, F. Rolland, and S. Oudard et al. Are tyrosine kinase inhibitors still active in patients with metastatic renal cell carcinoma previously treated with a tyrosine kinase inhibitor and everolimus? Experience of 36 patients treated in France in the RECORD-1 Trial Clin Genitourin Cancer 11 2013 128 133
    • (2013) Clin Genitourin Cancer , vol.11 , pp. 128-133
    • Blesius, A.1    Beuselinck, B.2    Chevreau, C.3    Ravaud, A.4    Rolland, F.5    Oudard, S.6
  • 44
    • 78049463142 scopus 로고    scopus 로고
    • Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma
    • G. Di Lorenzo, C. Buonerba, P. Federico, P. Rescigno, M. Milella, and C. Ortega et al. Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma Eur Urol 58 2010 906 911
    • (2010) Eur Urol , vol.58 , pp. 906-911
    • Di Lorenzo, G.1    Buonerba, C.2    Federico, P.3    Rescigno, P.4    Milella, M.5    Ortega, C.6
  • 45
    • 81955164171 scopus 로고    scopus 로고
    • Treatment of everolimus-resistant metastatic renal cell carcinoma with VEGF-targeted therapies
    • V. Grunwald, C. Seidel, M. Fenner, A. Ganser, J. Busch, and S. Weikert Treatment of everolimus-resistant metastatic renal cell carcinoma with VEGF-targeted therapies Br J Cancer 105 2011 1635 1639
    • (2011) Br J Cancer , vol.105 , pp. 1635-1639
    • Grunwald, V.1    Seidel, C.2    Fenner, M.3    Ganser, A.4    Busch, J.5    Weikert, S.6
  • 46
    • 84897414661 scopus 로고    scopus 로고
    • Phase 3 trial of dovitinib vs sorafenib in patients with metastatic renal cell carcinoma after 1 prior VEGF pathway-targeted and 1 prior mTOR inhibitor therapy
    • Abstract LBA-34
    • Motzer R, Szczylik C, Vogelzang NJ, Sternberg CN, Porta C, Zolnierek J, et al. Phase 3 trial of dovitinib vs sorafenib in patients with metastatic renal cell carcinoma after 1 prior VEGF pathway-targeted and 1 prior mTOR inhibitor therapy. European Congress of, Cancer 2013:Abstract LBA-34.
    • (2013) European Congress Of, Cancer
    • Motzer, R.1    Szczylik, C.2    Vogelzang, N.J.3    Sternberg, C.N.4    Porta, C.5    Zolnierek, J.6
  • 47
    • 84879526008 scopus 로고    scopus 로고
    • RECORD-3: Phase II randomized trial comparing sequential first-line everolimus and second-line sunitinib versus first-line sunitinib and second-line everolimus in patients with metastatic renal cell carcinoma
    • Abstract 4504
    • R. Motzer, C. Barrios, T. Kim, S. Falcon, T. Cosgriff, and W. Harker et al. RECORD-3: phase II randomized trial comparing sequential first-line everolimus and second-line sunitinib versus first-line sunitinib and second-line everolimus in patients with metastatic renal cell carcinoma J Clin Oncol 31 2013 Abstract 4504
    • (2013) J Clin Oncol , vol.31
    • Motzer, R.1    Barrios, C.2    Kim, T.3    Falcon, S.4    Cosgriff, T.5    Harker, W.6
  • 48
    • 84881543064 scopus 로고    scopus 로고
    • Oral and intravenously administered mTOR inhibitors for metastatic renal cell carcinoma: Pharmacokinetic considerations and clinical implications
    • R. Danesi, J.P. Boni, and A. Ravaud Oral and intravenously administered mTOR inhibitors for metastatic renal cell carcinoma: pharmacokinetic considerations and clinical implications Cancer Treat Rev 39 2013 784 792
    • (2013) Cancer Treat Rev , vol.39 , pp. 784-792
    • Danesi, R.1    Boni, J.P.2    Ravaud, A.3
  • 49
    • 43249131245 scopus 로고    scopus 로고
    • Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: A phase i tumor pharmacodynamic study in patients with advanced solid tumors
    • J. Tabernero, F. Rojo, E. Calvo, H. Burris, I. Judson, and K. Hazell et al. Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors J Clin Oncol 26 2008 1603 1610
    • (2008) J Clin Oncol , vol.26 , pp. 1603-1610
    • Tabernero, J.1    Rojo, F.2    Calvo, E.3    Burris, H.4    Judson, I.5    Hazell, K.6
  • 50
    • 43249086546 scopus 로고    scopus 로고
    • Phase i pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors
    • A. O'Donnell, S. Faivre, H.A. Burris 3rd, D. Rea, V. Papadimitrakopoulou, and N. Shand et al. Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors J Clin Oncol 26 2008 1588 1595
    • (2008) J Clin Oncol , vol.26 , pp. 1588-1595
    • O'Donnell, A.1    Faivre, S.2    Burris III, H.A.3    Rea, D.4    Papadimitrakopoulou, V.5    Shand, N.6
  • 51
    • 2942735384 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer
    • E. Raymond, J. Alexandre, S. Faivre, K. Vera, E. Materman, and J. Boni et al. Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer J Clin Oncol 22 2004 2336 2347
    • (2004) J Clin Oncol , vol.22 , pp. 2336-2347
    • Raymond, E.1    Alexandre, J.2    Faivre, S.3    Vera, K.4    Materman, E.5    Boni, J.6
  • 52
    • 33750321673 scopus 로고    scopus 로고
    • A phase i and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer
    • M. Hidalgo, J.C. Buckner, C. Erlichman, M.S. Pollack, J.P. Boni, and G. Dukart et al. A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer Clin Cancer Res 12 2006 5755 5763
    • (2006) Clin Cancer Res , vol.12 , pp. 5755-5763
    • Hidalgo, M.1    Buckner, J.C.2    Erlichman, C.3    Pollack, M.S.4    Boni, J.P.5    Dukart, G.6
  • 53
    • 45149094232 scopus 로고    scopus 로고
    • Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data
    • C. Tanaka, T. O'Reilly, J.M. Kovarik, N. Shand, K. Hazell, and I. Judson et al. Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data J Clin Oncol 26 2008 1596 1602
    • (2008) J Clin Oncol , vol.26 , pp. 1596-1602
    • Tanaka, C.1    O'Reilly, T.2    Kovarik, J.M.3    Shand, N.4    Hazell, K.5    Judson, I.6
  • 54
    • 1542398693 scopus 로고    scopus 로고
    • Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • M.B. Atkins, M. Hidalgo, W.M. Stadler, T.F. Logan, J.P. Dutcher, and G.R. Hudes et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma J Clin Oncol 22 2004 909 918
    • (2004) J Clin Oncol , vol.22 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3    Logan, T.F.4    Dutcher, J.P.5    Hudes, G.R.6
  • 55
    • 84876988997 scopus 로고    scopus 로고
    • Everolimus vs temsirolimus for advanced renal cell carcinoma: Use and use of resources in the US Oncology Network
    • N.J. Vogelzang, M. Bhor, Z. Liu, R. Dhanda, and T.E. Hutson Everolimus vs. temsirolimus for advanced renal cell carcinoma: use and use of resources in the US Oncology Network Clin Genitourin Cancer 11 2013 115 120
    • (2013) Clin Genitourin Cancer , vol.11 , pp. 115-120
    • Vogelzang, N.J.1    Bhor, M.2    Liu, Z.3    Dhanda, R.4    Hutson, T.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.