HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation

Oncotarget

Volumn 5, Issue 4, 2014, Pages 1091-1100

  Cobbs, Charles ^a,b   Khan, Sabeena ^a   Matlaf, Lisa ^a   McAllister, Sean ^a   Zider, Alex ^a   Yount, Garret ^a   Rahlin, Kenneth ^a   Harkins, Lualhati ^c   Bezrookove, Vladimir ^a   Singer, Eric ^a   Soroceanu, Liliana ^a  

^a CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^b SWEDISH MEDICAL CENTER   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Glioblastoma; Human cytomegalovirus glycoprotein B; Platelet derived growth factor receptor alfa; Slice invasion assay; Time lapse videomicroscopy; Tumor invasiveness

Indexed keywords

GLYCOPROTEIN B; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN; GLYCOPROTEIN B, SIMPLEXVIRUS; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE PROGRESSION; CONTROLLED STUDY; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; HUMAN TISSUE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TUMOR INVASION; VIRUS ENTRY; ANIMAL; BIOSYNTHESIS; BRAIN TUMOR; CELL MOTION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; FEMALE; METABOLISM; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VIROLOGY; XENOGRAFT;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; GLIOBLASTOMA; HETEROGRAFTS; HUMANS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SIGNAL TRANSDUCTION; VIRAL ENVELOPE PROTEINS;

EID: 84897382737     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1787     Document Type: Article

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