-
1
-
-
77749338221
-
Recent advances in therapy for glioblastoma
-
Clarke J, Butowski N, Chang S. Recent advances in therapy for glioblastoma. Arch Neurol 2010;67:279-83.
-
(2010)
Arch Neurol
, vol.67
, pp. 279-283
-
-
Clarke, J.1
Butowski, N.2
Chang, S.3
-
2
-
-
84859557807
-
Consensus on the role of human cytomegalovirus in glioblastoma
-
Dziurzynski K, Chang SM, Heimberger AB, Kalejta RF, McGregor Dallas SR, Smit M, et al. Consensus on the role of human cytomegalovirus in glioblastoma. Neuro Oncol 2012;14:246-55.
-
(2012)
Neuro Oncol
, vol.14
, pp. 246-255
-
-
Dziurzynski, K.1
Chang, S.M.2
Heimberger, A.B.3
Kalejta, R.F.4
McGregor Dallas, S.R.5
Smit, M.6
-
3
-
-
80155131275
-
Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype
-
Soroceanu L, Matlaf L, Bezrookove V, Harkins L, Martinez R, Greene M, et al. Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype. Cancer Res 2011;71:6643-53.
-
(2011)
Cancer Res
, vol.71
, pp. 6643-6653
-
-
Soroceanu, L.1
Matlaf, L.2
Bezrookove, V.3
Harkins, L.4
Martinez, R.5
Greene, M.6
-
4
-
-
38849124313
-
Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicity
-
Cobbs CS, Soroceanu L, Denham S, Zhang W, Kraus MH. Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicity. Cancer Res 2008;68:724-30.
-
(2008)
Cancer Res
, vol.68
, pp. 724-730
-
-
Cobbs, C.S.1
Soroceanu, L.2
Denham, S.3
Zhang, W.4
Kraus, M.H.5
-
5
-
-
84872757069
-
Low levels of human cytomegalovirus infection in glioblastoma multiforme associates with patient survival; - A case-control study
-
Rahbar A, Stragliotto G, Orrego A, Peredo I, Taher C, Willems J, et al. Low levels of human cytomegalovirus infection in glioblastoma multiforme associates with patient survival; - a case-control study. Herpesviridae 2012;3:3.
-
(2012)
Herpesviridae
, vol.3
, pp. 3
-
-
Rahbar, A.1
Stragliotto, G.2
Orrego, A.3
Peredo, I.4
Taher, C.5
Willems, J.6
-
6
-
-
77956635499
-
HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis
-
Slinger E, Maussang D, Schreiber A, Siderius M, Rahbar A, Fraile-Ramos A, et al. HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis. Sci Signal 2010;3:ra58.
-
(2010)
Sci Signal
, vol.3
-
-
Slinger, E.1
Maussang, D.2
Schreiber, A.3
Siderius, M.4
Rahbar, A.5
Fraile-Ramos, A.6
-
7
-
-
63649124717
-
Activation of telomerase by human cytomegalovirus
-
Straat K, Liu C, Rahbar A, Zhu Q, Liu L, Wolmer-Solberg N, et al. Activation of telomerase by human cytomegalovirus. J Natl Cancer Inst 2009;101:488-97.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 488-497
-
-
Straat, K.1
Liu, C.2
Rahbar, A.3
Zhu, Q.4
Liu, L.5
Wolmer-Solberg, N.6
-
8
-
-
84879247198
-
Effects of valganciclovir as an add-on therapy in patients with cytomegalovirus-positive glioblastoma: A randomized, doubleblind, hypothesis-generating study
-
Stragliotto G, Rahbar A, Solberg NW, Lilja A, Taher C, Orrego A, et al. Effects of valganciclovir as an add-on therapy in patients with cytomegalovirus-positive glioblastoma: a randomized, doubleblind, hypothesis-generating study. Int J Cancer 2013;133:1204-13.
-
(2013)
Int J Cancer
, vol.133
, pp. 1204-1213
-
-
Stragliotto, G.1
Rahbar, A.2
Solberg, N.W.3
Lilja, A.4
Taher, C.5
Orrego, A.6
-
9
-
-
34247275133
-
The acyclic nucleoside phosphonates from inception to clinical use: Historical perspective
-
De Clercq E. The acyclic nucleoside phosphonates from inception to clinical use: historical perspective. Antiviral Res 2007;75:1-13.
-
(2007)
Antiviral Res
, vol.75
, pp. 1-13
-
-
De Clercq, E.1
-
10
-
-
0023763320
-
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine, a potent and selective inhibitor of human cytomegalovirus replication
-
Snoeck R, Sakuma T, De Clercq E, Rosenberg I, Holy A. (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine, a potent and selective inhibitor of human cytomegalovirus replication. Antimicrob Agents Chemother 1988;32:1839-44.
-
(1988)
Antimicrob Agents Chemother
, vol.32
, pp. 1839-1844
-
-
Snoeck, R.1
Sakuma, T.2
De Clercq, E.3
Rosenberg, I.4
Holy, A.5
-
11
-
-
0035967619
-
Successful treatment of aids related PML with HAART and cidofovir
-
Zimmermann T, Stingele K, Hartmann M, Haas J, Von Einsiedel R, Wildemann B. Successful treatment of aids related PML with HAART and cidofovir. Eur J Med Res 2001;6:190-62.
-
(2001)
Eur J Med Res
, vol.6
, pp. 190-162
-
-
Zimmermann, T.1
Stingele, K.2
Hartmann, M.3
Haas, J.4
Von Einsiedel, R.5
Wildemann, B.6
-
12
-
-
0025552679
-
Biochemical pharmacology of acyclic nucleotide analogues
-
Bronson JJ, Ho HT, De Boeck H, Woods K, Ghazzouli I, Martin JC, et al. Biochemical pharmacology of acyclic nucleotide analogues. Ann N Y Acad Sci 1990;616:398-407.
-
(1990)
Ann N Y Acad Sci
, vol.616
, pp. 398-407
-
-
Bronson, J.J.1
Ho, H.T.2
De Boeck, H.3
Woods, K.4
Ghazzouli, I.5
Martin, J.C.6
-
13
-
-
33847133080
-
The nucleotide analog cidofovir suppresses basic fibroblast growth factor (FGF2) expression and signaling and induces apoptosis in FGF2-overexpressing endothelial cells
-
Liekens S, Gijsbers S, Vanstreels E, Daelemans D, De Clercq E, Hatse S. The nucleotide analog cidofovir suppresses basic fibroblast growth factor (FGF2) expression and signaling and induces apoptosis in FGF2-overexpressing endothelial cells. Mol Pharmacol 2007;71:695-703.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 695-703
-
-
Liekens, S.1
Gijsbers, S.2
Vanstreels, E.3
Daelemans, D.4
De Clercq, E.5
Hatse, S.6
-
15
-
-
67349157073
-
Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: Current state of the art
-
Hostetler KY. Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art. Antiviral Res 2009;82:A84-98.
-
(2009)
Antiviral Res
, vol.82
-
-
Hostetler, K.Y.1
-
16
-
-
0032250518
-
Inhibiting effects of cidofovir (HPMPC) on the growth of the human cervical carcinoma (SiHa) xenografts in athymic nude mice
-
Andrei G, Snoeck R, Piette J, Delvenne P, De Clercq E. Inhibiting effects of cidofovir (HPMPC) on the growth of the human cervical carcinoma (SiHa) xenografts in athymic nude mice. Oncol Res 1998;10:533-9.
-
(1998)
Oncol Res
, vol.10
, pp. 533-539
-
-
Andrei, G.1
Snoeck, R.2
Piette, J.3
Delvenne, P.4
De Clercq, E.5
-
17
-
-
0032525988
-
Potent inhibition of hemangioma formation in rats by the acyclic nucleoside phosphonate analogue cidofovir
-
Liekens S, Andrei G, Vandeputte M, De Clercq E, Neyts J. Potent inhibition of hemangioma formation in rats by the acyclic nucleoside phosphonate analogue cidofovir. Cancer Res 1998;58:2562-7.
-
(1998)
Cancer Res
, vol.58
, pp. 2562-2567
-
-
Liekens, S.1
Andrei, G.2
Vandeputte, M.3
De Clercq, E.4
Neyts, J.5
-
18
-
-
0035871997
-
Potent inhibition of hemangiosarcoma development in mice by cidofovir
-
Liekens S, Verbeken E, De Clercq E, Neyts J. Potent inhibition of hemangiosarcoma development in mice by cidofovir. Int J Cancer 2001;92:161-7.
-
(2001)
Int J Cancer
, vol.92
, pp. 161-167
-
-
Liekens, S.1
Verbeken, E.2
De Clercq, E.3
Neyts, J.4
-
19
-
-
0032005187
-
The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl- methoxypropyl) cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice
-
Neyts J, Sadler R, De Clercq E, Raab-Traub N, Pagano JS. The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl) cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice. Cancer Res 1998;58:384-8.
-
(1998)
Cancer Res
, vol.58
, pp. 384-388
-
-
Neyts, J.1
Sadler, R.2
De Clercq, E.3
Raab-Traub, N.4
Pagano, J.S.5
-
20
-
-
0035504712
-
Prevention and inhibition of nasopharyngeal carcinoma growth by antiviral phosphonated nucleoside analogs
-
Murono S, Raab-Traub N, Pagano JS. Prevention and inhibition of nasopharyngeal carcinoma growth by antiviral phosphonated nucleoside analogs. Cancer Res 2001;61:7875-7.
-
(2001)
Cancer Res
, vol.61
, pp. 7875-7877
-
-
Murono, S.1
Raab-Traub, N.2
Pagano, J.S.3
-
21
-
-
0035394723
-
Inhibition of fibroblast growth factor-2-induced vascular tumor formation by the acyclic nucleoside phosphonate cidofovir
-
Liekens S, Neyts J, De Clercq E, Verbeken E, Ribatti D, Presta M. Inhibition of fibroblast growth factor-2-induced vascular tumor formation by the acyclic nucleoside phosphonate cidofovir. Cancer Res 2001;61:5057-64.
-
(2001)
Cancer Res
, vol.61
, pp. 5057-5064
-
-
Liekens, S.1
Neyts, J.2
De Clercq, E.3
Verbeken, E.4
Ribatti, D.5
Presta, M.6
-
22
-
-
49649098258
-
Regulation of cancer progression by inhibition of angiogenesis and induction of apoptosis
-
Liekens S. Regulation of cancer progression by inhibition of angiogenesis and induction of apoptosis. Verh K Acad Geneeskd Belg 2008;70:175-91.
-
(2008)
Verh K Acad Geneeskd Belg
, vol.70
, pp. 175-191
-
-
Liekens, S.1
-
23
-
-
32544450329
-
Cidofovir incorporation into human keratinocytes with episomal HPV 16 results in nonselective cytotoxicity
-
Spanos WC, El-Deiry M, Lee JH. Cidofovir incorporation into human keratinocytes with episomal HPV 16 results in nonselective cytotoxicity. Ann Otol Rhinol Laryngol 2005;114:840-6.
-
(2005)
Ann Otol Rhinol Laryngol
, vol.114
, pp. 840-846
-
-
Spanos, W.C.1
El-Deiry, M.2
Lee, J.H.3
-
24
-
-
54949098894
-
Nucleoside analogs: Molecular mechanisms signaling cell death
-
Ewald B, Sampath D, Plunkett W. Nucleoside analogs: molecular mechanisms signaling cell death. Oncogene 2008;27:6522-37.
-
(2008)
Oncogene
, vol.27
, pp. 6522-6537
-
-
Ewald, B.1
Sampath, D.2
Plunkett, W.3
-
25
-
-
38649102173
-
Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy) propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand
-
Magee WC, Aldern KA, Hostetler KY, Evans DH. Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy) propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand. Antimicrob Agents Chemother 2008;52:586-97.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 586-597
-
-
Magee, W.C.1
Aldern, K.A.2
Hostetler, K.Y.3
Evans, D.H.4
-
26
-
-
0037018270
-
Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers
-
Abdulkarim B, Sabri S, Deutsch E, Chagraoui H, Maggiorella L, Thierry J, et al. Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers. Oncogene 2002;21:2334-46.
-
(2002)
Oncogene
, vol.21
, pp. 2334-2346
-
-
Abdulkarim, B.1
Sabri, S.2
Deutsch, E.3
Chagraoui, H.4
Maggiorella, L.5
Thierry, J.6
-
27
-
-
0037657521
-
Antiviral agent cidofovir decreases Epstein-Barr virus (EBV) oncoproteins and enhances the radiosensitivity in EBV-related malignancies
-
Abdulkarim B, Sabri S, Zelenika D, Deutsch E, Frascogna V, Klijanienko J, et al. Antiviral agent cidofovir decreases Epstein-Barr virus (EBV) oncoproteins and enhances the radiosensitivity in EBV-related malignancies. Oncogene 2003;22:2260-71.
-
(2003)
Oncogene
, vol.22
, pp. 2260-2271
-
-
Abdulkarim, B.1
Sabri, S.2
Zelenika, D.3
Deutsch, E.4
Frascogna, V.5
Klijanienko, J.6
-
28
-
-
15244363807
-
Antiviral activity of cidofovir on a naturally human papillomavirus-16 infected squamous cell carcinoma of the head and neck (SCCHN) cell line improves radiation sensitivity
-
Sirianni N, Wang J, Ferris RL. Antiviral activity of cidofovir on a naturally human papillomavirus-16 infected squamous cell carcinoma of the head and neck (SCCHN) cell line improves radiation sensitivity. Oral Oncol 2005;41:423-8.
-
(2005)
Oral Oncol
, vol.41
, pp. 423-428
-
-
Sirianni, N.1
Wang, J.2
Ferris, R.L.3
-
29
-
-
33847647117
-
Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
-
Soroceanu L, Kharbanda S, Chen R, Soriano RH, Aldape K, Misra A, et al. Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma. Proc Natl Acad Sci U S A 2007;104:3466-71.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3466-3471
-
-
Soroceanu, L.1
Kharbanda, S.2
Chen, R.3
Soriano, R.H.4
Aldape, K.5
Misra, A.6
-
30
-
-
34548848002
-
Bioluminescence monitoring of intracranial glioblastoma xenograft: Response to primary and salvage temozolomide therapy
-
Dinca EB, Sarkaria JN, Schroeder MA, Carlson BL, Voicu R, Gupta N, et al. Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy. J Neurosurg 2007;107:610-6.
-
(2007)
J Neurosurg
, vol.107
, pp. 610-616
-
-
Dinca, E.B.1
Sarkaria, J.N.2
Schroeder, M.A.3
Carlson, B.L.4
Voicu, R.5
Gupta, N.6
-
31
-
-
80355140553
-
Establishing intracranial brain tumor xenografts with subsequent analysis of tumor growth and response to therapy using bioluminescence imaging
-
Ozawa T, James CD. Establishing intracranial brain tumor xenografts with subsequent analysis of tumor growth and response to therapy using bioluminescence imaging. J Vis Exp 2010;41:1986.
-
(2010)
J Vis Exp
, vol.41
, pp. 1986
-
-
Ozawa, T.1
James, C.D.2
-
32
-
-
33746831189
-
Response of intracerebral human glioblastoma xenografts to multifraction radiation exposures
-
Ozawa T, Faddegon BA, Hu LJ, Bollen AW, Lamborn KR, Deen DF. Response of intracerebral human glioblastoma xenografts to multifraction radiation exposures. Int J Radiat Oncol Biol Phys 2006;66:263-70.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.66
, pp. 263-270
-
-
Ozawa, T.1
Faddegon, B.A.2
Hu, L.J.3
Bollen, A.W.4
Lamborn, K.R.5
Deen, D.F.6
-
33
-
-
0036903037
-
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
-
Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, et al. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat Cell Biol 2002;4:993-7.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 993-997
-
-
Fernandez-Capetillo, O.1
Chen, H.T.2
Celeste, A.3
Ward, I.4
Romanienko, P.J.5
Morales, J.C.6
-
35
-
-
0029704912
-
Therapeutic potential of Cidofovir (HPMPC, Vistide) for the treatment of DNA virus (ie herpes-, papova-, pox- and adenovirus) infections
-
discussion 47-9
-
De Clercq E. Therapeutic potential of Cidofovir (HPMPC, Vistide) for the treatment of DNA virus (i.e. herpes-, papova-, pox- and adenovirus) infections. Verh K Acad Geneeskd Belg 1996;58:19-47; discussion 47-9.
-
(1996)
Verh K Acad Geneeskd Belg
, vol.58
, pp. 19-47
-
-
De Clercq, E.1
-
36
-
-
0024041143
-
Antiviral activity and mechanism of action of ganciclovir
-
Matthews T, Boehme R. Antiviral activity and mechanism of action of ganciclovir. Rev Infect Dis 1988;10 Suppl 3:S490-4.
-
(1988)
Rev Infect Dis
, vol.10
, Issue.SUPPL. 3
-
-
Matthews, T.1
Boehme, R.2
-
37
-
-
23044457366
-
Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate
-
Magee WC, Hostetler KY, Evans DH. Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Antimicrob Agents Chemother 2005;49:3153-62.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 3153-3162
-
-
Magee, W.C.1
Hostetler, K.Y.2
Evans, D.H.3
-
39
-
-
76249106205
-
Human cytomegalovirus UL76 induces chromosome aberrations
-
Siew VK, Duh CY, Wang SK. Human cytomegalovirus UL76 induces chromosome aberrations. J Biomed Sci 2009;16:107
-
(2009)
J Biomed Sci
, vol.16
, pp. 107
-
-
Siew, V.K.1
Duh, C.Y.2
Wang, S.K.3
-
40
-
-
79958030662
-
An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus
-
Xiaofei E, Pickering MT, Debatis M, Castillo J, Lagadinos A, Wang S, et al. An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus. PLoS Pathog 2011;7:e1001342.
-
(2011)
PLoS Pathog
, vol.7
-
-
Xiaofei, E.1
Pickering, M.T.2
Debatis, M.3
Castillo, J.4
Lagadinos, A.5
Wang, S.6
-
41
-
-
84879802917
-
Cytomegalovirus pp71 protein is expressed in human glioblastoma and promotes pro-angiogenic signaling by activation of stem cell factor
-
Matlaf LA, Harkins LE, Bezrookove V, Cobbs CS, Soroceanu L. Cytomegalovirus pp71 protein is expressed in human glioblastoma and promotes pro-angiogenic signaling by activation of stem cell factor. PLoS ONE 2013;8:e68176
-
(2013)
PLoS ONE
, vol.8
-
-
Matlaf, L.A.1
Harkins, L.E.2
Bezrookove, V.3
Cobbs, C.S.4
Soroceanu, L.5
-
42
-
-
80053390591
-
Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target
-
Baryawno N, Rahbar A, Wolmer-Solberg N, Taher C, Odeberg J, Darabi A, et al. Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target. J Clin Invest 2011;121:4043-55.
-
(2011)
J Clin Invest
, vol.121
, pp. 4043-4055
-
-
Baryawno, N.1
Rahbar, A.2
Wolmer-Solberg, N.3
Taher, C.4
Odeberg, J.5
Darabi, A.6
-
43
-
-
75149195336
-
The transcriptional network for mesenchymal transformation of brain tumours
-
Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, et al. The transcriptional network for mesenchymal transformation of brain tumours. Nature 2010;463:318-25.
-
(2010)
Nature
, vol.463
, pp. 318-325
-
-
Carro, M.S.1
Lim, W.K.2
Alvarez, M.J.3
Bollo, R.J.4
Zhao, X.5
Snyder, E.Y.6
-
44
-
-
84881424926
-
Enhanced radiation sensitivity in HPV-positive head and neck cancer
-
Kimple RJ, Smith MA, Blitzer GC, Torres AD, Martin JA, Yang RZ, et al. Enhanced radiation sensitivity in HPV-positive head and neck cancer. Cancer Res 2013;73:4791-800.
-
(2013)
Cancer Res
, vol.73
, pp. 4791-4800
-
-
Kimple, R.J.1
Smith, M.A.2
Blitzer, G.C.3
Torres, A.D.4
Martin, J.A.5
Yang, R.Z.6
|