Early predictors for tissue healing deficit and leakage in geriatric critically ill patients receiving emergent abdominal surgery: A case control study

International Journal of Surgery

Volumn 12, Issue 4, 2014, Pages 315-319

  Wu, Shih Chi ^a,b   Fu, Chih Yuan ^c   Hsieh, Chi Hsun ^a,b   Wang, Yu Chun ^a,b   Lo, Hung Chieh ^a,b   Cheng, Han Tsung ^a   Tzeng, Chia Wei ^a  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Geriatric critical ill; Hypoalbuminemia; Vasopressor

Indexed keywords

ADRENALIN; DOPAMINE; NORADRENALIN;

ABDOMINAL SURGERY; AGED; ANASTOMOSIS LEAKAGE; APACHE; ARTICLE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; EMERGENCY WARD; EVISCERATION; FEMALE; GERIATRIC CARE; GERIATRIC PATIENT; HEALING; HUMAN; INTENSIVE CARE; INTESTINE PERFORATION; ISCHEMIA; LAPAROSCOPIC SURGERY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; OPERATIVE SITE BLEEDING; POSTOPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; WOUND DEHISCENCE; ABDOMEN; AGE; CASE CONTROL STUDY; CRITICAL ILLNESS; GERIATRICS; LAPAROTOMY; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE; PROCEDURES; REOPERATION; SURGERY; VERY ELDERLY; WOUND HEALING;

ABDOMEN; AGE FACTORS; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CRITICAL ILLNESS; FEMALE; GERIATRICS; HUMANS; LAPAROTOMY; MALE; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; REOPERATION; WOUND HEALING;

EID: 84897376952     PISSN: 17439191     EISSN: 17439159     Source Type: Journal    
DOI: 10.1016/j.ijsu.2014.01.016     Document Type: Article

References (44)

1. Sieber C.C. The elderly patient - who is that?. Internist (Berl.) 2007, 48:1190-1194.
2. Rockwood K., Song X., MacKnight C., et al. A global clinical measure of fitness and frailty in elderly people. CMAJ 2005, 30(173):489-495.
3. Ferrucci L., Guralnik J.M., Cavazzini C., et al. The frailty syndrome: a critical issue in geriatric oncology. Crit. Rev. Oncol. Hematol. 2003, 46:127-137.
4. Counsell S.R., Callahan C.M., Clark D.O., et al. Geriatric care management for low-income seniors: a randomized controlled trial. JAMA 2007, 298:2623-2633.
5. Abbas S., Booth M. Major abdominal surgery in octogenarians. N. Z. Med. J. 2003 Apr 17, 116(1172):U402.
6. Huang T.S., Hu F.C., Fan C.W., et al. A simple novel model to predict hospital mortality, surgical site infection, and pneumonia in elderly patients undergoing operation. Dig. Surg. 2010 Aug, 27(3):224-231.
7. Dellinger R.P., Levy M.M., Carlet J.M., et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit. Care Med. 2008, 36(1):296-327.
8. SAFE Study Investigators, Finfer S., Bellomo R., McEvoy S., et al. Effect of baseline serum albumin concentration on outcome of resuscitation with albumin or saline in patients in intensive care units: analysis of data from the saline versus albumin fluid evaluation (SAFE) study. BMJ 2006, 333(7577):1044.
9. Mohil R.S., Bhatnagar D., Bahadur L., et al. POSSUM and P-POSSUM for risk-adjusted audit of patients undergoing emergency laparotomy. Br. J. Surg. 2004, 91(4):500-503.
10. Tran Ba Loc P., du Montcel S.T., Duron J.J., et al. Elderly POSSUM, a dedicated score for prediction of mortality and morbidity after major colorectal surgery in older patients. Br. J. Surg. 2010, 97(3):396-403.
11. Kroon H.M., Breslau P.J., Lardenoye J.W., et al. Can the incidence of unplanned re-operations be used as an indicator of quality of care in surgery?. Am. J. Med. Qual. 2007, 22(3):198-202.
12. Louis D.J., Hsu A., Brand M.I., et al. Morbidity and mortality in octogenarians and older undergoing major intestinal surgery. Dis. Colon Rectum 2009, 52(1):59-63.
13. Story D.A. Postoperative complications in elderly patients and their significance for long-term prognosis. Curr. Opin. Anaesthesiol. 2008, 21(3):375-379.
14. Makary M.A., Segev D.L., Pronovost P.J., et al. Frailty as a predictor of surgical outcomes in older patients. J. Am. Coll. Surg. 2010, 210(6):901-908.
15. Hyman N.H. Managing anastomotic leaks from intestinal anastomoses. Surgeon 2009, 7(1):31-35.
16. Burger J.W., Lange J.F., Halm J.A., et al. Incisional hernia: early complication of abdominal surgery. World J. Surg. 2005, 29(12):1608-1613.
17. Ohmann C., Yang Q., Hau T., Wacha H. Prognostic modelling in peritonitis. Peritonitis Study Group of the Surgical Infection Society Europe. Eur. J. Surg. 1997, 163:53-60.
18. Pacelli F., Doglietto G.B., Alfieri S., et al. Prognosis in intra-abdominal infections. Multivariate analysis on 604 patients. Arch. Surg. 1996, 131:641-645.
19. Robinson T.N., Eiseman B., Wallace J.I., et al. Redefining geriatric preoperative assessment using frailty, disability and co-morbidity. Ann. Surg. 2009, 250(3):449-455.
20. Chang T.T., Schecter W.P. Injury in the elderly and end-of-life decisions. Surg. Clin. North Am. 2007, 87(1):229-245.
21. Marik P.E. Management of the critically ill geriatric patient. Crit. Care Med. 2006, 34(9 Suppl.):S176-S182.
22. Mikkelsen M.E., Miltiades A.N., Gaieski D.F., et al. Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock. Crit. Care Med. 2009, 37(5):1670-1677.
23. Trzeciak S., Dellinger R.P., Chansky M.E., et al. Serum lactate as a predictor of mortality in patients with infection. Intensive Care Med. 2007, 33(6):970-977.
24. Arnold R.C., Shapiro N.I., Jones A.E., et al. Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis. Shock 2009, 32(1):35-39.
25. Lang J.D., Figueroa M., Chumley P., et al. Albumin and hydroxyethyl starch modulate oxidative inflammatory injury to vascular endothelium. Anesthesiology 2004, 100:51-58.
26. Quinlan G.J., Margarson M.P., Mumby S., et al. Administration of albumin to patients with sepsis syndrome: a possible beneficial role in plasma thiol repletion. Clin. Sci. (Lond.) 1998, 95:459-465.
27. Daley J., Khuri S.F., Henderson W., et al. Risk adjustment of the postoperative morbidity rate for the comparative assessment of the quality of surgical care: results of the National Veterans Affairs Surgical Risk Study. J. Am. Coll. Surg. 1997, 185(4):328-340.
28. Golub R., Golub R.W., Cantu R., et al. A multivariate analysis of factors contributing to leakage of intestinal anastomoses. J. Am. Coll. Surg. 1997, 184(4):364-372.
29. Goldwasser P., Feldman J. Association of serum albumin and mortality risk. J. Clin. Epidemiol. 1997, 50(6):693-703.
30. Hennessey D.B., Burke J.P., Ni-Dhonochu T., et al. Preoperative hypoalbuminemia is an independent risk factor for the development of surgical site infection following gastrointestinal surgery: a multi-institutional study. Ann. Surg. 2010, 252(2):325-329.
31. Sung J., Bochicchio G.V., Joshi M., et al. Admission serum albumin is predictive of outcome in critically ill trauma patients. Am. Surg. 2004, 70(12):1099-1102.
32. Herrmann F.R., Safran C., Levkoff S.E., et al. Serum albumin level on admission as a predictor of death, length of stay, and readmission. Arch. Intern. Med. 1992, 152(1):125-130.
33. Nair A., Pai D.R., Jagdish S. Predicting anastomotic disruption after emergent small bowel surgery. Predicting anastomotic disruption after emergent small bowel surgery. Dig. Surg. 2006, 23(1-2):38-43.
34. Zakrison T., Nascimento B.A., Tremblay L.N., et al. Perioperative vasopressors are associated with an increased risk of gastrointestinal anastomotic leakage. World J. Surg. 2007, 31(8):1627-1634.
35. Eltarawy I.G., Etman Y.M., Zenati M., et al. Acute mesenteric ischemia: the importance of early surgical consultation. Am. Surg. 2009, 75(3):212-219.
36. Russell J.A. Vasopressin in vasodilatory and septic shock. Curr. Opin. Crit. Care 2007, 13(4):383-391.
37. Obritsch M.D., Bestul D.J., Jung R., et al. The role of vasopressin in vasodilatory septic shock. Pharmacotherapy 2004, 24(8):1050-1063.
38. Lin M.Y., Rezai K., Schwartz D.N. Septic pulmonary emboli and bacteremia associated with deep tissue infections caused by community-acquired methicillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 2008, 46(4):1553-1555.
39. Cook R.J., Ashton R.W., Aughenbaugh G.L., et al. Septic pulmonary embolism: presenting features and clinical course of 14 patients. Chest 2005, 128(1):162-166.
40. Abenza-Abildua M.J., Fuentes-Gimeno B., Morales-Bastos C., et al. Stroke due to septic embolism resulting from Aspergillus aortitis in an immunocompetent patient. J. Neurol. Sci. 2009; 15, 284(1-2):209-210.
41. Ruler O.V., Mahler C.W., Boer K.R., et al. Comparison of on-demand vs planned relaparotomy strategy in patients with severe peritonitis: a randomized trial. JAMA 2007, 298:865-873.
42. Dubois M.J., Orellana-Jimenez C., Melot C., et al. Albumin administration improves organ function in critically ill hypoalbuminemic patients: a prospective, randomized, controlled, pilot study. Crit. Care Med. 2006, 34(10):2536-2540.
43. Vincent J.L. Relevance of albumin in modern critical care medicine. Best Pract. Res. Clin. Anaesthesiol. 2009, 23(2):183-191.
44. Finfer S., Myburgh J., Bellomo R. Albumin supplementation and organ function. Crit. Care. Med. 2007, 35(3):987-988.