Rosemary (Rosmarinus officinalis) extract modulates CHOP/GADD153 to promote androgen receptor degradation and decreases xenograft tumor growth

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Petiwala, Sakina M ^a   Berhe, Saba ^a   Li, Gongbo ^a   Puthenveetil, Angela G ^a   Rahman, Ozair ^a   Nonn, Larisa ^a,b   Johnson, Jeremy J ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; ROSMARINUS OFFICINALIS EXTRACT; ANTINEOPLASTIC AGENT; DDIT3 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PROSTATE CANCER; PROSTATE EPITHELIUM; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TUMOR XENOGRAFT; ANIMAL; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; ENDOPLASMIC RETICULUM; GENE EXPRESSION; METABOLISM; NUDE MOUSE; PATHOLOGY; PROSTATIC NEOPLASMS; ROSMARINUS; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; MALE; MICE, NUDE; PLANT EXTRACTS; PROSTATIC NEOPLASMS; PROTEOLYSIS; RECEPTORS, ANDROGEN; ROSMARINUS; TRANSCRIPTION FACTOR CHOP; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84897146362     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089772     Document Type: Article

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