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Volumn 7, Issue 318, 2014, Pages

Flipping the switch: Integrin switching provides metastatic competence

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTEGRIN; BETA INTEGRIN; BETA1 INTEGRIN; HETERODIMER; INTEGRIN; LIGAND; MYC PROTEIN; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA;

EID: 84897145001     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005236     Document Type: Short Survey
Times cited : (18)

References (12)
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    • J. S. Desgrosellier, D. A. Cheresh, Integrins in cancer: Biological implications and therapeutic opportunities. Nat. Rev. Cancer 10, 9-22 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 3
    • 5144235557 scopus 로고    scopus 로고
    • Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
    • D. E. White, N. A. Kurpios, D. Zuo, J. A. Hassell, S. Blaess, U. Mueller, W. J. Muller, Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 6, 159-170 (2004).
    • (2004) Cancer Cell , vol.6 , pp. 159-170
    • White, D.E.1    Kurpios, N.A.2    Zuo, D.3    Hassell, J.A.4    Blaess, S.5    Mueller, U.6    Muller, W.J.7
  • 6
    • 84887074851 scopus 로고    scopus 로고
    • Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β
    • J. G. Parvani, A. J. Galliher-Beckley, B. J. Schiemann, W. P. Schiemann, Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β. Mol. Biol. Cell 24, 3449-3459 (2013).
    • (2013) Mol. Biol. Cell , vol.24 , pp. 3449-3459
    • Parvani, J.G.1    Galliher-Beckley, A.J.2    Schiemann, B.J.3    Schiemann, W.P.4
  • 7
    • 84861592850 scopus 로고    scopus 로고
    • MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits
    • H. Liu, D. C. Radisky, D. Yang, R. Xu, E. S. Radisky, M. J. Bissell, J. M. Bishop, MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits. Nat. Cell Biol. 14, 567-574 (2012).
    • (2012) Nat. Cell Biol. , vol.14 , pp. 567-574
    • Liu, H.1    Radisky, D.C.2    Yang, D.3    Xu, R.4    Radisky, E.S.5    Bissell, M.J.6    Bishop, J.M.7
  • 8
    • 84863229849 scopus 로고    scopus 로고
    • Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition
    • J. L. Leight, M. A. Wozniak, S. Chen, M. L. Lynch, C. S. Chen, Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition. Mol. Biol. Cell 23, 781-791 (2012).
    • (2012) Mol. Biol. Cell , vol.23 , pp. 781-791
    • Leight, J.L.1    Wozniak, M.A.2    Chen, S.3    Lynch, M.L.4    Chen, C.S.5
  • 9
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • B. D. Lehmann, J. A. Bauer, X. Chen, M. E. Sanders, A. B. Chakravarthy, Y. Shyr, J. A. Pietenpol, Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J. Clin. Invest. 121, 2750-2767 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6    Pietenpol, J.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.