Design and experimental evaluation of a 256-channel dual-frequency ultrasound phased-array system for transcranial blood-brain barrier opening and brain drug delivery

IEEE Transactions on Biomedical Engineering

Volumn 61, Issue 4, 2014, Pages 1350-1360

  Liu, Hao Li ^a   Jan, Chen Kai ^a   Chu, Po Chun ^a   Hong, Jhong Cing ^a   Lee, Pei Yun ^a   Hsu, Jyh Duen ^a   Lin, Chung Chih ^a   Huang, Chiung Ying ^a   Chen, Pin Yuan ^a   Wei, Kuo Chen ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Blood brain barrier (BBB); dual frequency; focused ultrasound (FUS); phased array

Indexed keywords

ANIMALS; BLOOD; DESIGN; DRUG DELIVERY; ELECTROMAGNETIC COMPATIBILITY; REGULATORY COMPLIANCE;

BLOOD-BRAIN BARRIER; DUAL FREQUENCY; DUAL-FREQUENCY ULTRASOUND; ELECTROMAGNETIC COMPATIBILITY STANDARDS; FOCUSED ULTRASOUND; PHASED-ARRAYS; TRANSISTOR-TRANSISTOR LOGIC; ULTRASOUND PHASED ARRAYS;

ULTRASONICS;

BIOCERAMICS; POLYVINYLIDENE FLUORIDE;

256 CHANNEL DUAL FREQUENCY ULTRASOUND PHASED ARRAY SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; ELECTRIC POTENTIAL; ERYTHROCYTE; EXTRAVASATION; HIGH INTENSITY FOCUSED ULTRASOUND; HUMAN; HUMAN TISSUE; MICROBUBBLE; NONHUMAN; PIEZOELECTRICITY; PRESSURE MEASUREMENT; SEMICONDUCTOR; SPECTROPHOTOMETRY; SWINE; ULTRASOUND; ULTRASOUND TRANSDUCER;

ANIMALS; BLOOD-BRAIN BARRIER; DRUG DELIVERY SYSTEMS; ECHOENCEPHALOGRAPHY; EQUIPMENT DESIGN; HUMANS; SKULL; SWINE; ULTRASONOGRAPHY, INTERVENTIONAL;

EID: 84897126035     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2014.2305723     Document Type: Article

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