Pharmacokinetic comparison of seven major bio-Active components in normal and blood deficiency rats after oral administration of Danggui Buxue decoction by UPLC-TQ/MS

Journal of Ethnopharmacology

Volumn 153, Issue 1, 2014, Pages 169-177

  Shi, Xuqin ^a   Tang, Yuping ^a   Zhu, Huaxu ^a   Li, Weixia ^a   Li, Zhenhao ^a   Luo, Niancui ^a   Duan, Jin Ao ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Bleeding; Blood deficiency; Comparison; Danggui Buxue Decoction; Pharmacokinetic; UPLC TQ MS

Indexed keywords

3 BUTYLPHTHALIDE; ASTRAGALOSIDE IV; CAFFEIC ACID; CALYCOSIN 7 O BETA GLUCOSIDE; CHINESE DRUG; CHLORAMPHENICOL; CLARITHROMYCIN; DANGGUI BUXUE DECOCTION; FERULIC ACID; GLUCOSIDE; LIGUSTILIDE; ONONIN; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ARTICLE; BLEEDING; CIRCULATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; QUADRUPOLE MASS SPECTROMETRY; RAT; SEX DIFFERENCE; SMALL INTESTINE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; AREA UNDER THE CURVE; CHINESE MEDICINE; DISEASE MODEL; HEMATOLOGIC DISEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT; VALIDATION STUDY;

ANIMALIA; DANGGUI; RATTUS;

ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FEMALE; HEMATOLOGIC DISEASES; MALE; MASS SPECTROMETRY; MEDICINE, CHINESE TRADITIONAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84897116579     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.02.004     Document Type: Article

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