메뉴 건너뛰기




Volumn 281, Issue 3, 2014, Pages 927-942

Estrogen receptor α mediates proliferation of breast cancer MCF-7 cells via a p21/PCNA/E2F1-dependent pathway

Author keywords

Estrogen receptor (ER ); MCF 7 cell proliferation; MiR 17; P21; PCNA

Indexed keywords

CYCLINE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; KI 67 ANTIGEN; MICRORNA; MIR 17; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

EID: 84897089978     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12658     Document Type: Article
Times cited : (139)

References (55)
  • 2
    • 0033818180 scopus 로고    scopus 로고
    • Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression
    • Zhou J, Ng S, Adesanya-Famuiya O, Anderson K & Bondy CA (2000) Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression. FASEB J 14, 1725-1730.
    • (2000) FASEB J , vol.14 , pp. 1725-1730
    • Zhou, J.1    Ng, S.2    Adesanya-Famuiya, O.3    Anderson, K.4    Bondy, C.A.5
  • 3
    • 78049352549 scopus 로고    scopus 로고
    • Estrogen receptor-A promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP
    • Sanchez AM, Flamini MI, Baldacci C, Goglia L, Genazzani AR & Simoncini T (2010) Estrogen receptor-a promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP. Mol Endocrinol 24, 2114-2125.
    • (2010) Mol Endocrinol , vol.24 , pp. 2114-2125
    • Sanchez, A.M.1    Flamini, M.I.2    Baldacci, C.3    Goglia, L.4    Genazzani, A.R.5    Simoncini, T.6
  • 4
    • 2942676455 scopus 로고    scopus 로고
    • Estrogens and their receptors in breast cancer progression: A dual role in cancer proliferation and invasion
    • Platet N, Cathiard AM, Gleizes M & Garcia M (2004) Estrogens and their receptors in breast cancer progression: a dual role in cancer proliferation and invasion. Crit Rev Oncol Hematol 51, 55-67.
    • (2004) Crit Rev Oncol Hematol , vol.51 , pp. 55-67
    • Platet, N.1    Cathiard, A.M.2    Gleizes, M.3    Garcia, M.4
  • 5
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • Clarke RB, Howell A, Potten CS & Anderson E (1997) Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 57, 4987-4991.
    • (1997) Cancer Res , vol.57 , pp. 4987-4991
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3    Anderson, E.4
  • 6
    • 0023576146 scopus 로고
    • Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue
    • Petersen OW, Høyer PE & van Deurs B (1987) Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue. Cancer Res 47, 5748-5751.
    • (1987) Cancer Res , vol.47 , pp. 5748-5751
    • Petersen, O.W.1    Høyer, P.E.2    Van Deurs, B.3
  • 7
    • 40349094958 scopus 로고    scopus 로고
    • Amping up estrogen receptors in breast cancer
    • Fowler AM & Alarid ET (2007) Amping up estrogen receptors in breast cancer. Breast Cancer Res 9, 305.
    • (2007) Breast Cancer Res , vol.9 , pp. 305
    • Fowler, A.M.1    Alarid, E.T.2
  • 8
    • 0032482437 scopus 로고    scopus 로고
    • Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells
    • Sweeney KJ, Swarbrick A, Sutherland RL & Musgrove EA (1998) Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells. Oncogene 16, 2865-2878.
    • (1998) Oncogene , vol.16 , pp. 2865-2878
    • Sweeney, K.J.1    Swarbrick, A.2    Sutherland, R.L.3    Musgrove, E.A.4
  • 9
    • 0022631868 scopus 로고
    • Induction of epidermal growth factor-related polypeptides by 17-b-estradiol in MCF-7 human breast cancer cells
    • Dickson RB, Huff KK, Spencer EM & Lippman ME (1986) Induction of epidermal growth factor-related polypeptides by 17-b-estradiol in MCF-7 human breast cancer cells. Endocrinology 118, 138-142.
    • (1986) Endocrinology , vol.118 , pp. 138-142
    • Dickson, R.B.1    Huff, K.K.2    Spencer, E.M.3    Lippman, M.E.4
  • 10
    • 77953383265 scopus 로고    scopus 로고
    • Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression
    • Yang C, Chen L, Li C, Lynch MC, Brisken C & Schmidt EV (2010) Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression. Mol Cell Biol 30, 3111-3125.
    • (2010) Mol Cell Biol , vol.30 , pp. 3111-3125
    • Yang, C.1    Chen, L.2    Li, C.3    Lynch, M.C.4    Brisken, C.5    Schmidt, E.V.6
  • 11
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-A (ERa) and represses ERa messenger RNA and protein expression in breast cancer cell lines
    • Adams BD, Furneaux H & White BA (2007) The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-a (ERa) and represses ERa messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 21, 1132-1147.
    • (2007) Mol Endocrinol , vol.21 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 12
    • 78650982065 scopus 로고    scopus 로고
    • MiR-17 suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes
    • Xu Y, Fang F, Zhang J, Josson S, St Clair WH & St Clair DK (2010) miR-17 suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes. PLoS ONE 22, e14356.
    • (2010) PLoS ONE , vol.22
    • Xu, Y.1    Fang, F.2    Zhang, J.3    Josson, S.4    St Clair, W.H.5    St Clair, D.K.6
  • 13
    • 33750376591 scopus 로고    scopus 로고
    • Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA
    • Hossain A, Kuo MT & Saunders GF (2006) Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol Cell Biol 26, 8191-8201.
    • (2006) Mol Cell Biol , vol.26 , pp. 8191-8201
    • Hossain, A.1    Kuo, M.T.2    Saunders, G.F.3
  • 14
    • 49749086530 scopus 로고    scopus 로고
    • A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
    • Yu Z, Wang C, Wang M, Li Z, Casimiro MC, Liu M, Wu K, Whittle J, Ju X, Hyslop T, et al. (2008) A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol 182, 509-517.
    • (2008) J Cell Biol , vol.182 , pp. 509-517
    • Yu, Z.1    Wang, C.2    Wang, M.3    Li, Z.4    Casimiro, M.C.5    Liu, M.6    Wu, K.7    Whittle, J.8    Ju, X.9    Hyslop, T.10
  • 20
    • 0029910364 scopus 로고    scopus 로고
    • Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRbcontrolled G1 checkpoint
    • Lukas J, Bartkova J & Bartek J (1996) Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRbcontrolled G1 checkpoint. Mol Cell Biol 16, 6917-6925.
    • (1996) Mol Cell Biol , vol.16 , pp. 6917-6925
    • Lukas, J.1    Bartkova, J.2    Bartek, J.3
  • 21
    • 75449112004 scopus 로고    scopus 로고
    • Expression of estrogen receptor a with a Tet-off adenoviral system induces G0/ G1 cell cycle arrest in SKBr 3 breast cancer cells
    • Peng J & Jordan VC (2010) Expression of estrogen receptor a with a Tet-off adenoviral system induces G0/ G1 cell cycle arrest in SKBr 3 breast cancer cells. Int J Oncol 36, 451-458.
    • (2010) Int J Oncol , vol.36 , pp. 451-458
    • Peng, J.1    Jordan, V.C.2
  • 22
    • 70449625948 scopus 로고    scopus 로고
    • Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast
    • Elayat G, Selim AG & Wells CA (2009) Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast. Breast J 15, 475-482.
    • (2009) Breast J , vol.15 , pp. 475-482
    • Elayat, G.1    Selim, A.G.2    Wells, C.A.3
  • 23
    • 33750975372 scopus 로고    scopus 로고
    • The role of estrogen in the initiation of breast cancer
    • Russo J & Russo IH (2006) The role of estrogen in the initiation of breast cancer. J Steroid Biochem Mol Biol 102, 89-96.
    • (2006) J Steroid Biochem Mol Biol , vol.102 , pp. 89-96
    • Russo, J.1    Russo, I.H.2
  • 24
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • DeGregori J & Johnson DG (2006) Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med. 6, 739-748.
    • (2006) Curr Mol Med. , vol.6 , pp. 739-748
    • Degregori, J.1    Johnson, D.G.2
  • 25
    • 0021333571 scopus 로고
    • Influence of cell proliferation and cell cycle phase on expression of estrogen receptor in MCF-7 breast cancer cells
    • Jakesz R, Smith CA, Aitken S, Huff K, Schuette W, Shackney S & Lippman M (1984) Influence of cell proliferation and cell cycle phase on expression of estrogen receptor in MCF-7 breast cancer cells. Cancer Res 44, 619-625.
    • (1984) Cancer Res , vol.44 , pp. 619-625
    • Jakesz, R.1    Smith, C.A.2    Aitken, S.3    Huff, K.4    Schuette, W.5    Shackney, S.6    Lippman, M.7
  • 26
    • 0034485142 scopus 로고    scopus 로고
    • Estrogen receptor a in human breast cancer: Occurrence and significance
    • Ali S & Coombes RC (2000) Estrogen receptor a in human breast cancer: occurrence and significance. J Mammary Gland Biol Neoplasia 5, 271-281.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 271-281
    • Ali, S.1    Coombes, R.C.2
  • 27
    • 0344951288 scopus 로고    scopus 로고
    • Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells
    • Mitropoulou TN, Tzanakakis GN, Kletsas D, Kalofonos HP & Karamanos NK (2003) Letrozole as a potent inhibitor of cell proliferation and expression of metalloproteinases (MMP-2 and MMP-9) by human epithelial breast cancer cells. Int J Cancer 104, 155-160.
    • (2003) Int J Cancer , vol.104 , pp. 155-160
    • Mitropoulou, T.N.1    Tzanakakis, G.N.2    Kletsas, D.3    Kalofonos, H.P.4    Karamanos, N.K.5
  • 29
    • 84865435566 scopus 로고    scopus 로고
    • Stable inhibition of specific estrogen receptor a (ERa) phosphorylation confers increased growth, migration/ invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells
    • Huderson BP, Duplessis TT, Williams CC, Seger HC, Marsden CG, Pouey KJ, Hill SM & Rowan BG (2012) Stable inhibition of specific estrogen receptor a (ERa) phosphorylation confers increased growth, migration/ invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells. Endocrinology 153, 4144-4159.
    • (2012) Endocrinology , vol.153 , pp. 4144-4159
    • Huderson, B.P.1    Duplessis, T.T.2    Williams, C.C.3    Seger, H.C.4    Marsden, C.G.5    Pouey, K.J.6    Hill, S.M.7    Rowan, B.G.8
  • 31
    • 40849089181 scopus 로고    scopus 로고
    • Effects of thyroid hormones on human breast cancer cell proliferation
    • Hall LC, Salazar EP, Kane SR & Liu N (2008) Effects of thyroid hormones on human breast cancer cell proliferation. J Steroid Biochem Mol Biol 109, 57-66.
    • (2008) J Steroid Biochem Mol Biol , vol.109 , pp. 57-66
    • Hall, L.C.1    Salazar, E.P.2    Kane, S.R.3    Liu, N.4
  • 33
    • 77949657113 scopus 로고    scopus 로고
    • PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule?
    • Soria G & Gottifredi V (2010) PCNA-coupled p21 degradation after DNA damage: the exception that confirms the rule? DNA Repair 9, 358-364.
    • (2010) DNA Repair , vol.9 , pp. 358-364
    • Soria, G.1    Gottifredi, V.2
  • 34
    • 84855415190 scopus 로고    scopus 로고
    • Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer
    • Zhao H, Ho PC, Lo YH, Espejo A, Bedford MT, Hung MC & Wang SC (2012) Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer. PLoS ONE 7, e29416.
    • (2012) PLoS ONE , vol.7
    • Zhao, H.1    Ho, P.C.2    Lo, Y.H.3    Espejo, A.4    Bedford, M.T.5    Hung, M.C.6    Wang, S.C.7
  • 35
    • 0033609369 scopus 로고    scopus 로고
    • Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin- proteasome pathway
    • Rousseau D, Cannella D, Boulaire J, Fitzgerald P, Fotedar A & Fotedar R (1999) Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin- proteasome pathway. Oncogene 18, 3290-3302.
    • (1999) Oncogene , vol.18 , pp. 3290-3302
    • Rousseau, D.1    Cannella, D.2    Boulaire, J.3    Fitzgerald, P.4    Fotedar, A.5    Fotedar, R.6
  • 37
    • 55849085008 scopus 로고    scopus 로고
    • Two estrogen response element sequences near the PCNA gene are not responsible for its estrogen-enhanced expression in MCF7 cells
    • Wang C, Yu J & Kallen CB (2008) Two estrogen response element sequences near the PCNA gene are not responsible for its estrogen-enhanced expression in MCF7 cells. PLoS ONE 3, e3523.
    • (2008) PLoS ONE , vol.3
    • Wang, C.1    Yu, J.2    Kallen, C.B.3
  • 40
    • 84877690804 scopus 로고    scopus 로고
    • Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells
    • Tsonis AI, Afratis N, Gialeli C, Ellina MI, Piperigkou Z, Skandalis SS, Theocharis AD, Tzanakakis GN & Karamanos NK (2013) Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells. FEBS J 280, 2248-2259.
    • (2013) FEBS J , vol.280 , pp. 2248-2259
    • Tsonis, A.I.1    Afratis, N.2    Gialeli, C.3    Ellina, M.I.4    Piperigkou, Z.5    Skandalis, S.S.6    Theocharis, A.D.7    Tzanakakis, G.N.8    Karamanos, N.K.9
  • 41
    • 33750970564 scopus 로고    scopus 로고
    • Contributions of estrogen to ER-negative breast tumor growth
    • Gupta PB & Kuperwasser C (2006) Contributions of estrogen to ER-negative breast tumor growth. J Steroid Biochem Mol Biol 102, 71-78.
    • (2006) J Steroid Biochem Mol Biol , vol.102 , pp. 71-78
    • Gupta, P.B.1    Kuperwasser, C.2
  • 42
    • 70349169955 scopus 로고    scopus 로고
    • ERa-negative and triple negative breast cancer: Molecular features and potential therapeutic approaches
    • Chen JQ & Russo J (2009) ERa-negative and triple negative breast cancer: molecular features and potential therapeutic approaches. Biochim Biophys Acta 796, 162-175.
    • (2009) Biochim Biophys Acta , vol.796 , pp. 162-175
    • Chen, J.Q.1    Russo, J.2
  • 43
    • 84874629992 scopus 로고    scopus 로고
    • MiR-126 and miR-126 repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis
    • Zhang Y, Yang P, Sun T, Li D, Xu X, Rui Y, Li C, Chong M, Ibrahim T, Mercatali L, et al. (2013) miR-126 and miR-126 repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol 15, 284-294.
    • (2013) Nat Cell Biol , vol.15 , pp. 284-294
    • Zhang, Y.1    Yang, P.2    Sun, T.3    Li, D.4    Xu, X.5    Rui, Y.6    Li, C.7    Chong, M.8    Ibrahim, T.9    Mercatali, L.10
  • 44
    • 66049147178 scopus 로고    scopus 로고
    • MicroRNAs 373 and 520c are downregulated in prostate cancer, suppress CD44 translation and enhance invasion of prostate cancer cells in vitro
    • Yang K, Handorean AM & Iczkowski KA (2009) MicroRNAs 373 and 520c are downregulated in prostate cancer, suppress CD44 translation and enhance invasion of prostate cancer cells in vitro. Int J Clin Exp Pathol 2, 361-369.
    • (2009) Int J Clin Exp Pathol , vol.2 , pp. 361-369
    • Yang, K.1    Handorean, A.M.2    Iczkowski, K.A.3
  • 46
    • 79957907561 scopus 로고    scopus 로고
    • MiR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1
    • Li H, Bian C, Liao L, Li J & Zhao RC (2011) miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1. Breast Cancer Res Treat 126, 565-575.
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 565-575
    • Li, H.1    Bian, C.2    Liao, L.3    Li, J.4    Zhao, R.C.5
  • 47
    • 34548336347 scopus 로고    scopus 로고
    • Estrogen-regulated gene networks in human breast cancer cells: Involvement of E2F1 in the regulation of cell proliferation
    • Stender JD, Frasor J, Komm B, Chang KC, Kraus WL & Katzenellenbogen BS (2007) Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation. Mol Endocrinol 21, 2112-2123.
    • (2007) Mol Endocrinol , vol.21 , pp. 2112-2123
    • Stender, J.D.1    Frasor, J.2    Komm, B.3    Chang, K.C.4    Kraus, W.L.5    Katzenellenbogen, B.S.6
  • 49
    • 69449099439 scopus 로고    scopus 로고
    • Effects of SMYD3 overexpression on transformation, serum dependence, and apoptosis sensitivity in NIH3T3 cells
    • Luo XG, Xi T, Guo S, Liu ZP, Wang N, Jiang Y & Zhang TC (2009) Effects of SMYD3 overexpression on transformation, serum dependence, and apoptosis sensitivity in NIH3T3 cells. IUBMB Life 61, 679-684.
    • (2009) IUBMB Life , vol.61 , pp. 679-684
    • Luo, X.G.1    Xi, T.2    Guo, S.3    Liu, Z.P.4    Wang, N.5    Jiang, Y.6    Zhang, T.C.7
  • 51
    • 79952199356 scopus 로고    scopus 로고
    • The guideline of the design and validation of MiRNA mimics
    • Wang Z (2011) The guideline of the design and validation of MiRNA mimics. Methods Mol Biol 676, 211-223.
    • (2011) Methods Mol Biol , vol.676 , pp. 211-223
    • Wang, Z.1
  • 52
    • 0019551730 scopus 로고
    • Western blotting': Electrophoretic transfer of proteins from sodium dodecyl sulfate- polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein a
    • Burnette WN (1981) 'Western blotting': electrophoretic transfer of proteins from sodium dodecyl sulfate- polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem 112, 195-203.
    • (1981) Anal Biochem , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 53
    • 79951986447 scopus 로고    scopus 로고
    • Myocardin-related transcription factor-A induces cardiomyocyte hypertrophy
    • Liao XH, Wang N, Liu QX, Qin T, Cao B, Cao DS & Zhang TC (2011) Myocardin-related transcription factor-A induces cardiomyocyte hypertrophy. IUBMB Life 63, 54-61.
    • (2011) IUBMB Life , vol.63 , pp. 54-61
    • Liao, X.H.1    Wang, N.2    Liu, Q.X.3    Qin, T.4    Cao, B.5    Cao, D.S.6    Zhang, T.C.7
  • 54
    • 0019905005 scopus 로고
    • An assessment of the immunofluorescence technique as a method for demonstrating the histological localization of tetrahydrocannabinol in mammalian tissues
    • Morley M & Gee DJ (1982) An assessment of the immunofluorescence technique as a method for demonstrating the histological localization of tetrahydrocannabinol in mammalian tissues. J Forensic Sci 27, 837-843.
    • (1982) J Forensic Sci , vol.27 , pp. 837-843
    • Morley, M.1    Gee, D.J.2
  • 55
    • 0024002556 scopus 로고
    • Luciferase reporter gene vectors for analysis of promoters and enhancers
    • Nordeen SK (1988) Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6, 454-458.
    • (1988) Biotechniques , vol.6 , pp. 454-458
    • Nordeen, S.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.