REV-ERB-ALPHA circadian gene variant associates with obesity in two independent populations: Mediterranean and North American

Molecular Nutrition and Food Research

Volumn 58, Issue 4, 2014, Pages 821-829

  Garaulet, Marta ^a,b   Smith, Caren E ^b   Gomez Abellán, Purificación ^a   Ordovás Montañés, María ^b   Lee, Yu Chi ^b   Parnell, Laurence D ^b   Arnett, Donna K ^c   Ordovás, José M ^b,d,e  

^a UNIVERSITY OF MURCIA   (Spain)

^b TUFTS UNIVERSITY   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^e IMDEA FOOD INSTITUTE   (Spain)

Author keywords

Circadian; Clock genes; Obesity; REV ERB ALPHA 1; Single nucleotide Polymorphism

Indexed keywords

NR1D1 PROTEIN, HUMAN; NUCLEAR RECEPTOR NR1D1;

ADULT; CALORIC INTAKE; CAUCASIAN; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; HUMAN; MALE; MIDDLE AGED; NORTH AMERICA; OBESITY; POPULATION GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM; SPAIN;

ADULT; ENERGY INTAKE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; HUMANS; MALE; MIDDLE AGED; NORTH AMERICA; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP D, MEMBER 1; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; SPAIN;

EID: 84897069545     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201300361     Document Type: Article

References (36)

1. Garaulet, M., Madrid, J. A., Chronobiological aspects of nutrition, metabolic syndrome and obesity. Adv. Drug Deliv. Rev. 2010, 62, 967-978.
2. Garaulet, M., Ordovás, J. M., Madrid, J. A., The chronobiology, etiology and pathophysiology of obesity. Int. J. Obes. 2010, 34, 1667-1683.
3. Liu, A. C., Tran, H. G., Zhang, E. E., Priest, A. A. et al., Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms. PLoS Genet. 2008, 4, e1000023.
4. Teboul, M., Gréchez-Cassiau, A., Guillaumond, F., Delaunay, F., How nuclear receptors tell time. J. Appl. Physiol. 2009, 107, 1965-1971.
5. Preitner, N., Damiola, F., Lopez-Molina, L., Zakany, J. et al., The orphan nuclear receptor REV-ERB alpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 2002, 110, 251-260.
6. Bugge, A., Feng, D., Everett, L. J., Briggs, E. R. et al., Rev-erbα and REV-ERBβ coordinately protect the circadian clock and normal metabolic function. Genes Dev. 2012, 26, 657-667.
7. Cho, H., Zhao, X., Hatori, M., Yu, R. T. et al., Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature 2012, 485, 123-127.
8. Kumar, N., Solt, L. A., Wang, Y., Rogers, P. M. et al., Regulation of adipogenesis by natural and synthetic REV-ERB ligands. Endocrinology 2010, 151, 3015-3025.
9. Solt, L. A., Wang, Y., Banerjee, S., Hughes, T. et al., Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature 2012, 485, 62-68.
10. Higgins, M., Province, M., Heiss, G., Eckfeldt, J. et al., NHLBI Family Heart Study, objectives and design. Am. J. Epidemiol. 1996, 143, 1219-1228.
11. Garaulet, M., Hernández-Morante, J. J., Tébar, F. J., Zamora, S., Anthropometric indexes for visceral fat estimation in overweight/obese women attending to age and menopausal status. J. Physiol. Biochem. 2006, 62, 245-252.
12. Shen, J., Arnett, D. K., Peacock, J. M., Parnell, L. D. et al., Interleukin1beta genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome. J. Nutr. 2007, 137, 1846-1851.
13. Sánchez-Moreno, C., Ordovás, J. M., Smith, C. E., Baraza, J. C. et al., APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population. J. Nutr. 2011, 141, 380-385.
14. Zimmet, P., Magliano, D., Matsuzawa, Y., Alberti, G. et al., The metabolic syndrome: a global public health problem and a new definition. J. Atheroscler. Thromb. 2005, 12, 295-300.
15. Pérez-Llamas, F., Garaulet, M., Herrero, F., Palma, J. T. et al., Multivalent informatics application for studies of the nutritional status of the population. Assessment of food intake. Nutr. Hosp. 2004, 19, 160-166 [Article in Spanish].
16. Mataix, J., Mañas, M., Llopis, J., Martínez, E., [Table of composition of Spanish foods] Tabla de composición de alimentos españoles (in Spanish). Granada, Spain, Instituto de Nutrición y Tecnología, Universidad de Granada, 1995.
17. Moreiras, O., Carvajal, A., Cabrera, L., in: Pirámide, S. A., (Ed.), [Table of composition of Spanish foods] Tablas de composición de alimentos (in Spanish). EUDEMA, SA, Madrid, Spain, 1995, p. 562.
18. Subar, A. F., Thompson, F. E., Kipnis, V., Midthune, D. et al., Comparative validation of the Block, Willett, and National Cancer Institute food frequency questionnaires: the Eating at America's Table Study. Am. J. Epidemiol. 2001, 154, 1089-1099.
19. Craig, C. L., Marshall, A. L., Sjöström, M., Bauman, A. E. et al., International Physical Activity Questionnaire: 12-country reliability and validity. Med. Sci. Sports Exerc. 2003, 35, 1381-1395.
20. Roman-Vinas, Serra-Majem, L., Hagstrom, M., Ribas-Barba, L. et al., International Physical Activity Questionnaire: reliability and validity in a Spanish population. Eur. J. Sport Sci. 2010, 10, 297-304.
21. Lai, C. Q., Tucker, K. L., Parnell, L. D., Adiconis, X. et al., PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study. Diabetes 2008, 57, 809-816.
22. Partonen, T., Clock gene variants in mood and anxiety disorders. J. Neural Transm. 2012, 119, 1133-1145.
23. Kripke, D. F., Nievergelt, C. M., Joo, E., Shekhtman, T. et al., Circadian polymorphisms associated with affective disorders. J. Circadian Rhythms 2009, 7, 2.
24. Campos-de-Sousa, S., Guindalini, C., Tondo, L., Munro, J. et al., Nuclear receptor REV-ERB-{alpha} circadian gene variants and lithium carbonate prophylaxis in bipolar affective disorder. J. Biol. Rhythms. 2010, 25, 132-137.
25. Corella, D., Arnett, D. K., Tsai, M. Y., Kabagambe, E. K. et al., The -256T>C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study. Clin Chem. 2007, 53, 1144-1152.
26. Garaulet, M., Pérez-Llamas, F., Pérez-Ayala, M., Martínez, P. et al., Site-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesity. Am. J. Clin Nutr. 2001, 74, 585-591.
27. Garaulet, M., Corbalán, M. D., Madrid, J. A., Morales, E. et al., CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet. Int. J. Obes. 2010, 34, 516-523.
28. Garaulet, M., Lee, Y. C., Shen, J., Parnell, L. D. et al., CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids. Am. J. Clin. Nutr. 2009, 90, 1466-1475.
29. Garaulet, M., Lee, Y. C., Shen, J., Parnell, L. D. et al., Genetic variants in human CLOCK associate with total energy intake and cytokine sleep factors in overweight subjects (GOLDN population). Eur. J. Hum. Genet. 2010, 18, 364-369.
30. Goumidi, L., Grechez, A., Dumont, J., Cottel, D. et al., Impact of REV-ERB alpha gene polymorphisms on obesity phenotypes in adult and adolescent samples. Int. J. Obes. 2013, 37, 666-672.
31. Garaulet, M., Ordovás, J. M., Gómez-Abellán, P., Martínez, J. A. et al., An approximation to the temporal order in endogenous circadian rhythms of genes implicated in human adipose tissue metabolism. J. Cell. Physiol. 2011, 226, 2075-2080.
32. Chawla, A., Lazar, M. A., Induction of REV-ERBA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation. J. Biol. Chem. 1993, 268, 16265-16269.
33. Laitinen, S., Fontaine, C., Fruchart, J. C., Staels, B., The role of the orphan nuclear receptor REV-ERB alpha in adipocyte differentiation and function. Biochimie 2005, 87, 21-25.
34. Munroe, S. H., Lazar, M. A., Inhibition of c-erbA mRNA splicing by a naturally occurring antisense RNA. J. Biol. Chem. 1991, 266, 22083-22086.
35. Woldt, E., Sebti, Y., Solt, L. A., Duhem, C. et al., REV-ERB-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. Nat. Med. 2013, 19, 1039-1046.
36. Fontaine, C., Dubois, G., Duguay, Y., Helledie, T. et al., The orphan nuclear receptor Rev-Erb alpha is a peroxisome proliferator-activated receptor (PPAR) gamma target gene and promotes PPARgamma-induced adipocyte differentiation. J. Biol. Chem. 2003, 278, 37672-37680.