Metabolism: Tick, tock, a high-fat clock

Nature Reviews Endocrinology

Volumn 10, Issue 4, 2014, Pages 191-192

  Liu, Sihao ^a   Evans, Ronald M ^b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK; TRANSCRIPTOME;

ARTICLE; CIRCADIAN RHYTHM; DNA SEQUENCE; FOOD INTAKE; LIPID DIET; METABOLIC SYNDROME X; METABOLOMICS; NONHUMAN; NUTRIENT; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUPRACHIASMATIC NUCLEUS; TRANSCRIPTION REGULATION;

ANIMALS; CIRCADIAN CLOCKS; DIET, HIGH-FAT; MALE; METABOLIC NETWORKS AND PATHWAYS;

EID: 84897060711     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2014.23     Document Type: Article

References (10)

1. Eckel-Mahan, K. L. et al. Reprogramming of the circadian clock by nutritional challenge. Cell 155, 1464-1478 (2013).
2. Panda, S. et al. Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109, 307-320 (2002).
3. Turek, F. W. et al. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 308, 1043-1045 (2005).
4. Kohsaka, A. et al. High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab. 6, 414-421 (2007).
5. Jonker, J. W. et al. A PPAR?-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature 485, 391-394 (2012).
6. Cho, H. et al. Regulation of circadian behaviour and metabolism by REV-ERB-? and REV-ERB-?. Nature 485, 123-127 (2012).
7. Yang, X. et al. Nuclear receptor expression links the circadian clock to metabolism. Cell 126, 801-810 (2006).
8. Fontaine, C. et al. The orphan nuclear receptor Rev-Erb? is a peroxisome proliferator-activated receptor (PPAR) ? target gene and promotes PPAR?-induced adipocyte differentiation. J. Biol. Chem. 278, 37672-37680 (2003).
9. Ji, Y. et al. Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4. J. Biol. Chem. 287, 24378-24386 (2012).
10. Matsusue, K. et al. Liver-specific disruption of PPAR? in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J. Clin. Invest. 111, 737-747 (2003).