The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment

Clinical Endocrinology

Volumn 80, Issue 3, 2014, Pages 425-431

  An, Yuan ^a   Sun, Zhuangzhuang ^a   Zhang, Yajuan ^a   Liu, Bin ^a   Guan, Yuanyuan ^a   Lu, Meisong ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; FOLLITROPIN; GLUCOSE; INSULIN; LIPID; METFORMIN; PLACEBO; TESTOSTERONE;

ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; DIARRHEA; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; GASTROINTESTINAL SYMPTOM; HUMAN; INCIDENCE; LIVE BIRTH; MAJOR CLINICAL STUDY; METABOLIC PARAMETERS; NAUSEA; OVARY HYPERSTIMULATION; OVARY POLYCYSTIC DISEASE; PREGNANCY OUTCOME; PREGNANCY RATE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; WEIGHT REDUCTION;

ADULT; BERBERINE; FEMALE; FERTILIZATION IN VITRO; HUMANS; HYPOGLYCEMIC AGENTS; INFERTILITY, FEMALE; METFORMIN; OVARIAN HYPERSTIMULATION SYNDROME; OVULATION INDUCTION; POLYCYSTIC OVARY SYNDROME; PREGNANCY; PREGNANCY RATE; YOUNG ADULT;

EID: 84897053696     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12294     Document Type: Article

References (24)

1. Lee, Y.S., Kim, W.S., Kim, K.H. et al. (2006) Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes, 55, 2256-2264.
2. Tang, T., Glanville, J., Orsi, N. et al. (2006) The use of metformin for women with PCOS undergoing IVF treatment. Human Reproduction, 21, 1416-1425.
3. Azziz, R., Woods, K.S., Reyna, R. et al. (2004) The prevalence and features of the polycystic ovary syndrome in an unselected population. Journal of Clinical Endocrinology and Metabolism, 89, 2745-2749.
4. Geller, D.H., Pacaud, D., Gordon, C.M. et al. (2011) State of the art review: emerging therapies: the use of insulin sensitizers in the treatment of adolescents with polycystic ovary syndrome (PCOS). International Journal of Pediatric Endocrinology, 2011, 2011-2019.
5. Prelević, G.M., Würzburger, M.I. & Balint-Peric, L. (1990) LH pulsatility and response to a single s.c. injection of buserelin in polycystic ovary syndrome. Gynecological Endocrinology, 4, 1-13.
6. Nestler, J.E., Powers, L.P., Matt, D.W. et al. (1991) A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 72, 83-89.
7. Legro, R.S., Castracane, V.D. & Kauffman, R.P. (2004) Detecting insulin resistance in polycystic ovary syndrome: purposes and pitfalls. Obstetrical & Gynecological Survey, 59, 141-154.
8. Azziz, R. (2006) Controversy in clinical endocrinology: diagnosis of polycystic ovarian syndrome: the Rotterdam criteria are premature. Journal of Clinical Endocrinology and Metabolism, 91, 781-785.
9. Buyalos, R.P. & Lee, C.T. (1996) Polycystic ovary syndrome: pathophysiology and outcome with in vitro fertilization. Fertility and Sterility, 65, 1-10.
10. Haas, D.A., Carr, B.R. & Attia, G.R. (2003) Effects of metformin on body mass index, menstrual cyclicity, and ovulation induction in women with polycystic ovary syndrome. Fertility and Sterility, 79, 469-481.
11. Harborne, L., Fleming, R., Lyall, H. et al. (2003) Descriptive review of the evidence for the use of metformin in polycystic ovary syndrome. Lancet, 361, 1894-1901.
12. Kjøtrød, S.B., von Düring, V. & Carlsen, S.M. (2004) Metformin treatment before IVF/ICSI in women with polycystic ovary syndrome; a prospective, randomized, double blind study. Human Reproduction, 19, 1315-1322.
13. Yin, J., Xing, H. & Ye, J. (2008) Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism, 57, 712-717.
14. Wei, W., Zhao, H., Wang, A. et al. (2012) A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome. European Journal of Endocrinology, 166, 99-105.
15. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group (2004) Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertility and Sterility, 81, 19-25.
16. Vuddanda, P.R., Chakraborty, S. & Singh, S. (2010) Berberine: a potential phytochemical with multispectrum therapeutic activities. Expert Opinion on Investigational Drugs, 19, 1297-1307.
17. Chen, C., Zhang, Y. & Huang, C. (2010) Berberine inhibits PTP1B activity and mimics insulin action. Biochemical and Biophysical Research Communications, 397, 543-547.
18. Turner, N., Li, J.Y., Gosby, A. et al. (2008) Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action. Diabetes, 57, 1414-1418.
19. Zhou, L., Yang, Y., Wang, X. et al. (2007) Berberine stimulates glucose transport through a mechanism distinct from insulin. Metabolism, 56, 405-412.
20. Zhang, H., Wei, J., Xue, R. et al. (2010) Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism, 59, 285-292.
21. Hoeger, K., Davidson, K., Kochman, L. et al. (2008) The impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women in two randomized, placebo-controlled clinical trials. Journal of Clinical Endocrinology and Metabolism, 93, 4299-4306.
22. Mansfield, R., Galea, R., Brincat, M. et al. (2003) Metformin has direct effects on human ovarian steroidogenesis. Fertility and Sterility, 79, 956-962.
23. Legro, R.S., Barnhart, H.X., Schlaff, W.D. et al. (2007) Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. New England Journal of Medicine, 356, 551-566.
24. Zuo, F., Nakamura, N., Akao, T. et al. (2006) Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry. Drug Metabolism and Disposition, 34, 2064-2072.