Bipolar II disorder is associated with thinning of prefrontal and temporal cortices involved in affect regulation

Bipolar Disorders

Volumn 15, Issue 8, 2013, Pages 855-864

  Elvsåshagen, Torbjørn ^a,b   Westlye, Lars T ^a,b   Bøen, Erlend ^a,b   Hol, Per K ^a   Andreassen, Ole A ^a,b   Boye, Birgitte ^a   Malt, Ulrik F ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Bipolar II disorder; Cortical surface area; Cortical thickness; Cortical thinning; Prefrontal cortex; Temporal cortex

Indexed keywords

ADULT; ANTERIOR CINGULATE; ARTICLE; BIPOLAR II DISORDER; BRAIN CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; CORTICAL THICKNESS (BRAIN); DISEASE DURATION; DSM-IV; FAMILY HISTORY; FEMALE; HUMAN; INFERIOR TEMPORAL GYRUS; MALE; MIDDLE TEMPORAL GYRUS; MONTGOMERY ASBERG DEPRESSION RATING SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PREFRONTAL CORTEX; PRIORITY JOURNAL; SUPERIOR TEMPORAL GYRUS; TEMPORAL CORTEX; VENTROMEDIAL PREFRONTAL CORTEX; YOUNG MANIA RATING SCALE;

BIPOLAR II DISORDER; CORTICAL SURFACE AREA; CORTICAL THICKNESS; CORTICAL THINNING; PREFRONTAL CORTEX; TEMPORAL CORTEX;

ADOLESCENT; ADULT; BIPOLAR DISORDER; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; PREFRONTAL CORTEX; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; STATISTICS, NONPARAMETRIC; TEMPORAL LOBE; YOUNG ADULT;

EID: 84897042986     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/bdi.12117     Document Type: Article

References (83)

1. Lopez AD, Murray CC. The global burden of disease, 1990-2020. Nat Med 1998; 4: 1241-1243.
2. Angst J. The bipolar spectrum. Br J Psychiatry 2007; 190: 189-191.
3. Angst J, Cui L, Swendsen J et al. Major depressive disorder with subthreshold bipolarity in the National Comorbidity Survey Replication. Am J Psychiatry 2010; 167: 1194-1201.
4. Belmaker RH. Bipolar disorder. N Engl J Med 2004; 351: 476-486.
5. Berk M, Dodd S. Bipolar II disorder: a review. Bipolar Disord 2005; 7: 11-21.
6. Benazzi F. Bipolar disorder-focus on bipolar II disorder and mixed depression. Lancet 2007; 369: 935-945.
7. Smoller JW, Finn CT. Family, twin, and adoption studies of bipolar disorder. Am J Med Genet C Semin Med Genet 2003; 123C: 48-58.
8. Huang J, Perlis RH, Lee PH et al. Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. Am J Psychiatry 2010; 167: 1254-1263.
9. Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 1999; 9: 179-194.
10. Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system. Neuroimage 1999; 9: 195-207.
11. Fischl B, Dale AM. Measuring the thickness of the human cerebral cortex from magnetic resonance images. Proc Natl Acad Sci USA 2000; 97: 11050-11055.
12. Joyner AH, J CR, Bloss CS et al. A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations. Proc Natl Acad Sci USA 2009; 106: 15483-15488.
13. Rimol LM, Agartz I, Djurovic S et al. Sex-dependent association of common variants of microcephaly genes with brain structure. Proc Natl Acad Sci USA 2010; 107: 384-388.
14. Winkler AM, Sabuncu MR, Yeo BT et al. Measuring and comparing brain cortical surface area and other areal quantities. Neuroimage 2012; 61: 1428-1443.
15. Panizzon MS, Fennema-Notestine C, Eyler LT et al. Distinct genetic influences on cortical surface area and cortical thickness. Cereb Cortex 2009; 19: 2728-2735.
16. Winkler AM, Kochunov P, Blangero J et al. Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage 2010; 53: 1135-1146.
17. Lyoo IK, Sung YH, Dager SR et al. Regional cerebral cortical thinning in bipolar disorder. Bipolar Disord 2006; 8: 65-74.
18. Rimol LM, Hartberg CB, Nesvag R et al. Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder. Biol Psychiatry 2010; 68: 41-50.
19. Hulshoff Pol HE, van Baal GC, Schnack HG et al. Overlapping and segregating structural brain abnormalities in twins with schizophrenia or bipolar disorder. Arch Gen Psychiatry 2012; 69: 349-359.
20. Hartberg CB, Sundet K, Rimol LM et al. Brain cortical thickness and surface area correlates of neurocognitive performance in patients with schizophrenia, bipolar disorder, and healthy adults. J Int Neuropsychol Soc 2011; 17: 1080-1093.
21. Sheehan DV, Lecrubier Y, Sheehan KH et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998; 59 (Suppl. 20): 22-33.
22. Suppes T, Leverich GS, Keck PE et al. The Stanley Foundation Bipolar Treatment Outcome Network. II. Demographics and illness characteristics of the first 261 patients. J Affect Disord 2001; 67: 45-59.
23. Drake R, Mueser K, McHugo G. Clinical rating scales: Alcohol Use Scale (AUS), Drug Use Scale (DUS), and Substance Abuse Treatment Scale (SAYS). In: Sederer L, Dickey B eds. Outcomes Assessment in Clinical Practice. Baltimore: Williams & Wilkins, 1996: 113-116.
24. Montgomery SA, Åsberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134: 382-389.
25. Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978; 133: 429-435.
26. Dale AM, Sereno MI. Improved localization of cortical activity by combining EEG and MEG with MRI cortical surface reconstruction: a linear approach. J Cogn Neurosci 1993; 5: 162-176.
27. Fischl B, Sereno MI, Tootell RB, Dale AM. High-resolution intersubject averaging and a coordinate system for the cortical surface. Hum Brain Mapp 1999; 8: 272-284.
28. Fischl B, Liu A, Dale AM. Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex. IEEE Trans Med Imaging 2001; 20: 70-80.
29. Fischl B, Salat DH, van der Kouwe AJ et al. Sequence-independent segmentation of magnetic resonance images. Neuroimage 2004; 23 (Suppl. 1): S69-S84.
30. Desikan RS, Segonne F, Fischl B et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 2006; 31: 968-980.
31. Hayasaka S, Nichols TE. Validating cluster size inference: random field and permutation methods. Neuroimage 2003; 20: 2343-2356.
32. Hagler DJ Jr, Saygin AP, Sereno MI. Smoothing and cluster thresholding for cortical surface-based group analysis of fMRI data. Neuroimage 2006; 33: 1093-1103.
33. Phillips ML, Ladouceur CD, Drevets WC. A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder. Mol Psychiatry 2008; 13: 829, 833-857.
34. Mayberg HS. Targeted electrode-based modulation of neural circuits for depression. J Clin Invest 2009; 119: 717-725.
35. Price JL, Drevets WC. Neural circuits underlying the pathophysiology of mood disorders. Trends Cogn Sci 2012; 16: 61-71.
36. Myers-Schulz B, Koenigs M. Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. Mol Psychiatry 2012; 17: 132-141.
37. Olson IR, Plotzker A, Ezzyat Y. The Enigmatic temporal pole: a review of findings on social and emotional processing. Brain 2007; 130: 1718-1731.
38. Mayberg HS, Lozano AM, Voon V et al. Deep brain stimulation for treatment-resistant depression. Neuron 2005; 45: 651-660.
39. Price JL, Drevets WC. Neurocircuitry of mood disorders. Neuropsychopharmacology 2010; 35: 192-216.
40. Drevets WC, Price JL, Simpson JR Jr et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997; 386: 824-827.
41. Kaur S, Sassi RB, Axelson D et al. Cingulate cortex anatomical abnormalities in children and adolescents with bipolar disorder. Am J Psychiatry 2005; 162: 1637-1643.
42. Sassi RB, Brambilla P, Hatch JP et al. Reduced left anterior cingulate volumes in untreated bipolar patients. Biol Psychiatry 2004; 56: 467-475.
43. Haznedar MM, Roversi F, Pallanti S et al. Fronto-thalamo-striatal gray and white matter volumes and anisotropy of their connections in bipolar spectrum illnesses. Biol Psychiatry 2005; 57: 733-742.
44. Brambilla P, Nicoletti MA, Harenski K et al. Anatomical MRI study of subgenual prefrontal cortex in bipolar and unipolar subjects. Neuropsychopharmacology 2002; 27: 792-799.
45. Sanches M, Sassi RB, Axelson D et al. Subgenual prefrontal cortex of child and adolescent bipolar patients: a morphometric magnetic resonance imaging study. Psychiatry Res 2005; 138: 43-49.
46. Ha TH, Ha K, Kim JH, Choi JE. Regional brain gray matter abnormalities in patients with bipolar II disorder: a comparison study with bipolar I patients and healthy controls. Neurosci Lett 2009; 456: 44-48.
47. Holtzheimer PE, Kelley ME, Gross RE et al. Subcallosal cingulate deep brain stimulation for treatment-resistant unipolar and bipolar depression. Arch Gen Psychiatry 2012; 69: 150-158.
48. Narita K, Suda M, Takei Y et al. Volume reduction of ventromedial prefrontal cortex in bipolar II patients with rapid cycling: a voxel-based morphometric study. Prog Neuropsychopharmacol Biol Psychiatry 2011; 35: 439-445.
49. Wacker J, Dillon DG, Pizzagalli DA. The role of the nucleus accumbens and rostral anterior cingulate cortex in anhedonia: integration of resting EEG, fMRI, and volumetric techniques. Neuroimage 2009; 46: 327-337.
50. Grabenhorst F, D'Souza AA, Parris BA, Rolls ET, Passingham RE. A common neural scale for the subjective pleasantness of different primary rewards. Neuroimage 2010; 51: 1265-1274.
51. Sharot T, Riccardi AM, Raio CM, Phelps EA. Neural mechanisms mediating optimism bias. Nature 2007; 450: 102-105.
52. O'Doherty J, Winston J, Critchley H, Perrett D, Burt DM, Dolan RJ. Beauty in a smile: the role of medial orbitofrontal cortex in facial attractiveness. Neuropsychologia 2003; 41: 147-155.
53. Osuch EA, Bluhm RL, Williamson PC, Theberge J, Densmore M, Neufeld RW. Brain activation to favorite music in healthy controls and depressed patients. Neuroreport 2009; 20: 1204-1208.
54. Pizzagalli D, Pascual-Marqui RD, Nitschke JB et al. Anterior cingulate activity as a predictor of degree of treatment response in major depression: evidence from brain electrical tomography analysis. Am J Psychiatry 2001; 158: 405-415.
55. Kennedy SH, Konarski JZ, Segal ZV et al. Differences in brain glucose metabolism between responders to CBT and venlafaxine in a 16-week randomized controlled trial. Am J Psychiatry 2007; 164: 778-788.
56. Judd LL, Akiskal HS, Schettler PJ et al. A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder. Arch Gen Psychiatry 2003; 60: 261-269.
57. Ochsner KN, Gross JJ. Cognitive emotion regulation: insights from social, cognitive and affective neuroscience. Cur Dir Psych Sci 2008; 17: 153-158.
58. Levesque J, Eugene F, Joanette Y et al. Neural circuitry underlying voluntary suppression of sadness. Biol Psychiatry 2003; 53: 502-510.
59. Phan KL, Fitzgerald DA, Nathan PJ, Moore GJ, Uhde TW, Tancer ME. Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study. Biol Psychiatry 2005; 57: 210-219.
60. Goldin PR, McRae K, Ramel W, Gross JJ. The neural bases of emotion regulation: reappraisal and suppression of negative emotion. Biol Psychiatry 2008; 63: 577-586.
61. Ochsner KN, Bunge SA, Gross JJ, Gabrieli JD. Rethinking feelings: an FMRI study of the cognitive regulation of emotion. J Cogn Neurosci 2002; 14: 1215-1229.
62. Vizueta N, Rudie JD, Townsend JD et al. Regional fMRI hypoactivation and altered functional connectivity during emotion processing in nonmedicated depressed patients with bipolar II disorder. Am J Psychiatry 2012; 169: 831-840.
63. Dickstein DP, Milham MP, Nugent AC et al. Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry study. Arch Gen Psychiatry 2005; 62: 734-741.
64. Nugent AC, Milham MP, Bain EE et al. Cortical abnormalities in bipolar disorder investigated with MRI and voxel-based morphometry. Neuroimage 2006; 30: 485-497.
65. Hulvershorn LA, Karne H, Gunn AD et al. Neural activation during facial emotion processing in unmedicated bipolar depression, euthymia, and mania. Biol Psychiatry 2012; 71: 603-610.
66. 1H MRS study. Bipolar Disord 2007; 9 (Suppl. 1): 119-127.
67. Brooks JO 3rd, Wang PW, Bonner JC et al. Decreased prefrontal, anterior cingulate, insula, and ventral striatal metabolism in medication-free depressed outpatients with bipolar disorder. J Psychiatr Res 2009; 43: 181-188.
68. Winsberg ME, Sachs N, Tate DL, Adalsteinsson E, Spielman D, Ketter TA. Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder. Biol Psychiatry 2000; 47: 475-481.
69. Foland-Ross LC, Thompson PM, Sugar CA et al. Investigation of cortical thickness abnormalities in lithium-free adults with bipolar I disorder using cortical pattern matching. Am J Psychiatry 2011; 168: 530-539.
70. Etkin A, Egner T, Kalisch R. Emotional processing in anterior cingulate and medial prefrontal cortex. Trends Cogn Sci 2012; 15: 85-93.
71. Pelletier M, Bouthillier A, Levesque J et al. Separate neural circuits for primary emotions? Brain activity during self-induced sadness and happiness in professional actors. Neuroreport 2003; 14: 1111-1116.
72. Kimbrell TA, George MS, Parekh PI et al. Regional brain activity during transient self-induced anxiety and anger in healthy adults. Biol Psychiatry 1999; 46: 454-465.
73. Aalto S, Naatanen P, Wallius E et al. Neuroanatomical substrata of amusement and sadness: a PET activation study using film stimuli. Neuroreport 2002; 13: 67-73.
74. Ambrosi E, Rossi-Espagnet MC, Kotzalidis GD et al. Structural brain alterations in bipolar disorder II: a combined voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) study. J Affect Disord 2013. doi:10.1016/j.jad.2013.02.023.
75. Ongur D, Drevets WC, Price JL. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc Natl Acad Sci USA 1998; 95: 13290-13295.
76. Todtenkopf MS, Vincent SL, Benes FM. A cross-study meta-analysis and three-dimensional comparison of cell counting in the anterior cingulate cortex of schizophrenic and bipolar brain. Schizophr Res 2005; 73: 79-89.
77. Rajkowska G, Halaris A, Selemon LD. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biol Psychiatry 2001; 49: 741-752.
78. Rimol LM, Nesvag R, Hagler DJ Jr et al. Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder. Biol Psychiatry 2012; 71: 552-560.
79. Rakic P. Specification of cerebral cortical areas. Science 1988; 241: 170-176.
80. Rakic P, Ayoub AE, Breunig JJ, Dominguez MH. Decision by division: making cortical maps. Trends Neurosci 2009; 32: 291-301.
81. Frodl TS, Koutsouleris N, Bottlender R et al. Depression-related variation in brain morphology over 3 years: effects of stress? Arch Gen Psychiatry 2008; 65: 1156-1165.
82. Moorhead TW, McKirdy J, Sussmann JE et al. Progressive gray matter loss in patients with bipolar disorder. Biol Psychiatry 2007; 62: 894-900.
83. Koo MS, Levitt JJ, Salisbury DF, Nakamura M, Shenton ME, McCarley RW. A cross-sectional and longitudinal magnetic resonance imaging study of cingulate gyrus gray matter volume abnormalities in first-episode schizophrenia and first-episode affective psychosis. Arch Gen Psychiatry 2008; 65: 746-760.