-
1
-
-
0017084681
-
Characteristics of C-fibre receptors in the cat's foot responding to stepwise increase of skin temperature of noxious levels
-
Handwerker HO, Neher KD (1976) Characteristics of C-fibre receptors in the cat's foot responding to stepwise increase of skin temperature of noxious levels. Pflugers Arch 365: 221-229.
-
(1976)
Pflugers Arch
, vol.365
, pp. 221-229
-
-
Handwerker, H.O.1
Neher, K.D.2
-
2
-
-
0016872221
-
Sensitization of high threshold receptors with unmyelinated (C) afferent fibers
-
Perl ER, Kumazawa T, Lynn B, Kenins P (1976) Sensitization of high threshold receptors with unmyelinated (C) afferent fibers. Prog Brain Res 43: 263-277.
-
(1976)
Prog Brain Res
, vol.43
, pp. 263-277
-
-
Perl, E.R.1
Kumazawa, T.2
Lynn, B.3
Kenins, P.4
-
3
-
-
33748053352
-
Hypernociceptive role of cytokines and chemokines: Targets for analgesic drug development?
-
DOI 10.1016/j.pharmthera.2006.04.001, PII S0163725806000544
-
Verri WA Jr, Cunha TM, Parada CA, Poole S, Cunha FQ, et al. (2006) Hyperalgesic role of cytokines and chemokines: targets for analgesic drug development? Pharmacol Ther 112: 116-138. (Pubitemid 44301486)
-
(2006)
Pharmacology and Therapeutics
, vol.112
, Issue.1
, pp. 116-138
-
-
Verri Jr., W.A.1
Cunha, T.M.2
Parada, C.A.3
Poole, S.4
Cunha, F.Q.5
Ferreira, S.H.6
-
4
-
-
34648852375
-
TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor
-
Cunha TM, Verri WA Jr, Fukada SY, Guerrero AT, Santodomingo-Garzón T, et al. (2007) TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor. Eur J Pharmacol 573: 221-229.
-
(2007)
Eur J Pharmacol
, vol.573
, pp. 221-229
-
-
Cunha, T.M.1
Verri Jr., W.A.2
Fukada, S.Y.3
Guerrero, A.T.4
Santodomingo- Garzón, T.5
-
5
-
-
13444306159
-
A cascade of cytokines mediates mechanical inflammatory hypernociception in mice
-
DOI 10.1073/pnas.0409225102
-
Cunha TM, Verri WA Jr, Silva JS, Poole S, Cunha FQ, et al. (2005) A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc Natl Acad Sci U S A 102: 1755-1760. (Pubitemid 40209240)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.5
, pp. 1755-1760
-
-
Cunha, T.M.1
Verri Jr., W.A.2
Silva, J.S.3
Poole, S.4
Cunha, F.Q.5
Ferreira, S.H.6
-
6
-
-
48049087189
-
Dual role of hydrogen sulfide in mechanical inflammatory hypernociception
-
Cunha TM, Dal-Secco D, Verri WA Jr, Guerrero AT, Souza GR, et al. (2008) Dual role of hydrogen sulfide in mechanical inflammatory hypernociception. Eur J Pharmacol 590: 127-135.
-
(2008)
Eur J Pharmacol
, vol.590
, pp. 127-135
-
-
Cunha, T.M.1
Dal-Secco, D.2
Verri Jr., W.A.3
Guerrero, A.T.4
Souza, G.R.5
-
7
-
-
20544474210
-
Pathogen recognition with Toll-like receptors
-
DOI 10.1016/j.coi.2005.02.007, PII S0952791505000798
-
Kawai T, Akira S (2005) Pathogen recognition with Toll-like receptors. Curr Opin Immunol 17: 338-344. (Pubitemid 40848534)
-
(2005)
Current Opinion in Immunology
, vol.17
, Issue.4 SPEC. ISS.
, pp. 338-344
-
-
Kawai, T.1
Akira, S.2
-
8
-
-
0028027868
-
The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat
-
DOI 10.1016/0028-3908(94)90051-5
-
Meller ST, Dykstra C, Grzybycki D, Murphy S, Gebhart GF (1994) The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat. Neuropharmacology 33: 1471-1478. (Pubitemid 24353743)
-
(1994)
Neuropharmacology
, vol.33
, Issue.11
, pp. 1471-1478
-
-
Meller, S.T.1
Dykstra, C.2
Grzybycki, D.3
Murphy, S.4
Gebhart, G.F.5
-
9
-
-
60149097714
-
Differential microglial activation between acute stress and lipopolysaccharide treatment
-
Sugama S, Takenouchi T, Fujita M, Conti B, Hashimoto M (2009) Differential microglial activation between acute stress and lipopolysaccharide treatment. J Neuroimmunol 207: 24-31.
-
(2009)
J Neuroimmunol
, vol.207
, pp. 24-31
-
-
Sugama, S.1
Takenouchi, T.2
Fujita, M.3
Conti, B.4
Hashimoto, M.5
-
10
-
-
0031008485
-
Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone
-
DOI 10.1038/sj.bjp.0701211
-
Ferreira SH, Cunha FQ, Lorenzetti BB, Michelin MA, Perretti M, et al. (1997) Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone. Br J Pharmacol 121: 883-888 (Pubitemid 27277781)
-
(1997)
British Journal of Pharmacology
, vol.121
, Issue.5
, pp. 883-888
-
-
Ferreira, S.H.1
Cunha, F.Q.2
Lorenzetti, B.B.3
Michelin, M.A.4
Perretti, M.5
Flower, R.J.6
Poole, S.7
-
11
-
-
1842450784
-
An electronic pressure-meter nociception paw test for mice
-
Cunha TM, Verri WA Jr, Vivancos GG, Moreira IF, Reis S, et al. (2004) An electronic pressure-meter nociception paw test for mice. Braz J Med Biol Res 37: 401-407. (Pubitemid 38444531)
-
(2004)
Brazilian Journal of Medical and Biological Research
, vol.37
, Issue.3
, pp. 401-407
-
-
Cunha, T.M.1
Verri Jr., W.A.2
Vivancos, G.G.3
Moreira, I.F.4
Reis, S.5
Parada, C.A.6
Cunha, F.Q.7
Ferreira, S.H.8
-
12
-
-
67349285907
-
Roles of endothelin ETA and ETB receptors in nociception and chemical, thermal and mechanical hyperalgesia induced by endothelin-1 in the rat hindpaw
-
Motta EM, Chichorro JG, D'Orléans-Juste P, Rae GA (2009) Roles of endothelin ETA and ETB receptors in nociception and chemical, thermal and mechanical hyperalgesia induced by endothelin-1 in the rat hindpaw. Peptides 30: 918-925.
-
(2009)
Peptides
, vol.30
, pp. 918-925
-
-
Motta, E.M.1
Chichorro, J.G.2
D'Orléans-Juste, P.3
Rae, G.A.4
-
13
-
-
33746892303
-
Protective effect of topical formulations containing quercetin against UVB-induced oxidative stress in hairless mice
-
DOI 10.1016/j.jphotobiol.2006.01.006, PII S1011134406000285
-
Casagrande R, Georgetti SR, Verri WA Jr, Dorta DJ, dos Santos AC, et al. (2006) Protective effect of topical formulations containing quercetin against UVB-induced oxidative stress in hairless mice. J Photochem Photobiol 84: 21-27. (Pubitemid 44182726)
-
(2006)
Journal of Photochemistry and Photobiology B: Biology
, vol.84
, Issue.1
, pp. 21-27
-
-
Casagrande, R.1
Georgetti, S.R.2
Verri Jr., W.A.3
Dorta, D.J.4
Dos, S.A.C.5
Fonseca, M.J.V.6
-
14
-
-
3242807395
-
Functions of toll-like receptors: Lessons from KO mice
-
DOI 10.1016/j.crvi.2004.04.002, PII S1631069104000812
-
Akira S, Takeda K (2004) Functions of toll-like receptors: lessons from KO mice. C R Biol 327: 581-589. (Pubitemid 38979508)
-
(2004)
Comptes Rendus - Biologies
, vol.327
, Issue.6
, pp. 581-589
-
-
Akira, S.1
Takeda, K.2
-
15
-
-
3142743115
-
Toll-like receptors and their place in immunology. Where does the immune response to infection begin?
-
Beutler B (2004) Toll-like receptors and their place in immunology. Where does the immune response to infection begin? Nat Rev Immunol 4: 498-498.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 498-498
-
-
Beutler, B.1
-
16
-
-
77954716659
-
TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2
-
Gais P, Tiedje C, Altmayr F, Gaestel M, Weighardt H, et al. (2010) TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2. J Immunol 184: 5842-5848.
-
(2010)
J Immunol
, vol.184
, pp. 5842-5848
-
-
Gais, P.1
Tiedje, C.2
Altmayr, F.3
Gaestel, M.4
Weighardt, H.5
-
17
-
-
84885930898
-
Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells
-
Endale M, Park SC, Kim S, Kim SH, Yang Y, et al. (2013) Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells. Immunobiology 218: 1452-1467.
-
(2013)
Immunobiology
, vol.218
, pp. 1452-1467
-
-
Endale, M.1
Park, S.C.2
Kim, S.3
Kim, S.H.4
Yang, Y.5
-
18
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
DOI 10.1038/90609
-
Akira S, Takeda K, Kaisho T (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nature Immunol 2: 675-680. (Pubitemid 32747155)
-
(2001)
Nature Immunology
, vol.2
, Issue.8
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
19
-
-
67649208478
-
The endogenous Toll- like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer
-
Ehrchen JM, Sunderkötter C, Foell D, Vogl T, Roth J (2009) The endogenous Toll- like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer. J Leukoc Biol 86: 557-566.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 557-566
-
-
Ehrchen, J.M.1
Sunderkötter, C.2
Foell, D.3
Vogl, T.4
Roth, J.5
-
20
-
-
84883739860
-
Bacteria activate sensory neurons that modulate pain and inflammation
-
Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, et al. (2013) Bacteria activate sensory neurons that modulate pain and inflammation. Nature 501: 52-57.
-
(2013)
Nature
, vol.501
, pp. 52-57
-
-
Chiu, I.M.1
Heesters, B.A.2
Ghasemlou, N.3
Von Hehn, C.A.4
Zhao, F.5
-
21
-
-
0037307855
-
A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes
-
Shen H, Whitmire JK, Fan X, Shedlock DJ, Kaech SM, et al. (2003) A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes. J Immunol 170 (3): 1443-51. (Pubitemid 36139513)
-
(2003)
Journal of Immunology
, vol.170
, Issue.3
, pp. 1443-1451
-
-
Shen, H.1
Whitmire, J.K.2
Fan, X.3
Shedlock, D.J.4
Kaech, S.M.5
Ahmed, R.6
-
22
-
-
4744370253
-
Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4
-
DOI 10.1111/j.1365-2567.2004.01976.x
-
Palsson-McDermott EM, O'Neill LA (2004) Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4. Immunology 113: 153-162. (Pubitemid 39312442)
-
(2004)
Immunology
, vol.113
, Issue.2
, pp. 153-162
-
-
Palsson-McDermott, E.M.1
O'Neill, L.A.J.2
-
23
-
-
0034602150
-
Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase
-
Rhee SH, Hwang D (2000) Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase. J Biol Chem 275: 34035-34040
-
(2000)
J Biol Chem
, vol.275
, pp. 34035-34040
-
-
Rhee, S.H.1
Hwang, D.2
-
24
-
-
0037352702
-
Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages
-
DOI 10.1002/eji.200323376
-
Ojaniemi M, Glumoff V, Harju K, Liljeroos M, Vuori K, et al. (2003) Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages. Eur J Immunol 3: 597-605. (Pubitemid 36367663)
-
(2003)
European Journal of Immunology
, vol.33
, Issue.3
, pp. 597-605
-
-
Ojaniemi, M.1
Glumoff, V.2
Harju, K.3
Liljeroos, M.4
Vuori, K.5
Hallman, M.6
-
25
-
-
79955536232
-
Absence of TRIF signaling in lipopolysaccharide-stimulated murine mast cells
-
Keck S, Müller I, Fejer G, Savic I, Tchaptchet S, et al. (2011) Absence of TRIF signaling in lipopolysaccharide-stimulated murine mast cells. J Immunol 186: 5478-5488.
-
(2011)
J Immunol
, vol.186
, pp. 5478-5488
-
-
Keck, S.1
Müller, I.2
Fejer, G.3
Savic, I.4
Tchaptchet, S.5
-
26
-
-
0034043956
-
Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression
-
Medvedev AE, Kopydlowski KM, Vogel SN (2000) Inhibition of lipopolysac-charide- induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J Immunol 164: 5564-5574 (Pubitemid 30389795)
-
(2000)
Journal of Immunology
, vol.164
, Issue.11
, pp. 5564-5574
-
-
Medvedev, A.E.1
Kopydlowski, K.M.2
Vogel, S.N.3
-
27
-
-
0036824633
-
1 (CINC-1) mediates the sympathetic component of inflammatory mechanical hypersensitivity in rats
-
Lorenzetti BB, Veiga FH, Canetti CA, Poole S, Cunha FQ, et al. (2002) Cytokine-induced neutrophil chemoattractant 1 (CINC-1) mediates the sympathetic component of inflammatory mechanical hypersensitivitiy in rats. Eur Cytokine Netw 13: 456-461. (Pubitemid 36174104)
-
(2002)
European Cytokine Network
, vol.13
, Issue.4
, pp. 456-461
-
-
Lorenzetti, B.B.1
Veiga, F.H.2
Canetti, C.A.3
Poole, S.4
Cunha, F.Q.5
Ferreira, S.H.6
-
28
-
-
0023679882
-
Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue
-
Ferreira SH, Lorenzetti BB, Bristow AF, Poole S (1988) Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue. Nature 334: 698-700.
-
(1988)
Nature
, vol.334
, pp. 698-700
-
-
Ferreira, S.H.1
Lorenzetti, B.B.2
Bristow, A.F.3
Poole, S.4
-
29
-
-
0026787367
-
The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia
-
Cunha FQ, Poole S, Lorenzetti BB, Ferreira SH (1992) The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br J Pharmacol 107: 660-664.
-
(1992)
Br J Pharmacol
, vol.107
, pp. 660-664
-
-
Cunha, F.Q.1
Poole, S.2
Lorenzetti, B.B.3
Ferreira, S.H.4
-
30
-
-
40649127225
-
IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice
-
DOI 10.1073/pnas.0712116105
-
Verri WA Jr, Guerrero AT, Fukada SY, Valerio DA, Cunha TM, et al. (2008) IL-33 mediates antigen-induced cutaneous and articular hyperalgesia in mice. Proc Natl Acad Sci U S A 105: 2723-2728. (Pubitemid 351520580)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.7
, pp. 2723-2728
-
-
Verri Jr., W.A.1
Guerrero, A.T.G.2
Fukada, S.Y.3
Valerio, D.A.4
Cunha, T.M.5
Xu, D.6
Ferreira, S.H.7
Liew, F.Y.8
Cunha, F.Q.9
-
31
-
-
0020051148
-
Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker
-
Bradley PP, Priebat DA, Christensen RD, Rothstein G (1982) Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78: 206-209. (Pubitemid 12171880)
-
(1982)
Journal of Investigative Dermatology
, vol.78
, Issue.3
, pp. 206-209
-
-
Bradley, P.P.1
Priebat, D.A.2
Christensen, R.D.3
Rothstein, G.4
-
32
-
-
43449100478
-
Crucial role of neutrophils in the development of mechanical inflammatory hypernociception
-
DOI 10.1189/jlb.0907654
-
Cunha TM, Verri WA Jr, Schivo IR, Napimoga MH, Parada CA, et al. (2008) Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol 83: 824-32. (Pubitemid 351959862)
-
(2008)
Journal of Leukocyte Biology
, vol.83
, Issue.4
, pp. 824-832
-
-
Cunha, T.M.1
Verri Jr., W.A.2
Schivo, I.R.3
Napimoga, M.H.4
Parada, C.A.5
Poole, S.6
Teixeira, M.M.7
Ferreira, S.H.8
Cunha, F.Q.9
-
33
-
-
38149064496
-
Involvement of LTB4 in zymosan-induced joint nociception in mice: Participation of neutrophils and PGE2
-
Guerrero AT, Verri WA Jr, Cunha TM, Silva TA, Schivo IR, et al. (2008) Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2. J Leukoc Biol 83: 122-30.
-
(2008)
J Leukoc Biol
, vol.83
, pp. 122-130
-
-
Guerrero, A.T.1
Verri Jr., W.A.2
Cunha, T.M.3
Silva, T.A.4
Schivo, I.R.5
-
34
-
-
69549126273
-
Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: Role of adenosine acting on A1 receptors
-
Valério DA, Ferreira FI, Cunha TM, Alves-Filho JC, Lima FO, et al. (2009) Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors. Br. J. Pharmacol 158: 558-568.
-
(2009)
Br. J. Pharmacol
, vol.158
, pp. 558-568
-
-
Valério, D.A.1
Ferreira, F.I.2
Cunha, T.M.3
Alves-Filho, J.C.4
Lima, F.O.5
-
35
-
-
84877619379
-
Targeting the Toll-like receptor/interleukin 1 receptor pathway in human diseases: Rational design of MyD88 inhibitors
-
Loiarro M, Ruggiero V, Sette C (2013) Targeting the Toll-like receptor/interleukin 1 receptor pathway in human diseases: rational design of MyD88 inhibitors. Clin Lymphoma Myeloma Leuk 13: 222-226.
-
(2013)
Clin Lymphoma Myeloma Leuk
, vol.13
, pp. 222-226
-
-
Loiarro, M.1
Ruggiero, V.2
Sette, C.3
-
36
-
-
84863574462
-
Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque
-
Shinya K, Gao Y, Cilloniz C, Suzuki Y, Fujie M, et al. (2012) Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque. J Virol 86: 6055-6066.
-
(2012)
J Virol
, vol.86
, pp. 6055-6066
-
-
Shinya, K.1
Gao, Y.2
Cilloniz, C.3
Suzuki, Y.4
Fujie, M.5
-
37
-
-
84872861418
-
Modulating the innate immune response by combinatorial engineering of endotoxin
-
Needham BD, Carroll SM, Giles DK, Georgiou G, Whiteley M, et al. (2013) Modulating the innate immune response by combinatorial engineering of endotoxin. Proc Natl Acad Sci U S A 110: 1464-1469.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 1464-1469
-
-
Needham, B.D.1
Carroll, S.M.2
Giles, D.K.3
Georgiou, G.4
Whiteley, M.5
-
38
-
-
84874033208
-
TRIF is required for TLR4 mediated adjuvant effects on T cell clonal expansion
-
Gandhapudi SK, Chilton PM, Mitchell TC (2013) TRIF is required for TLR4 mediated adjuvant effects on T cell clonal expansion. PLoS One 8: e56855.
-
(2013)
PLoS One
, vol.8
-
-
Gandhapudi, S.K.1
Chilton, P.M.2
Mitchell, T.C.3
|