Development and validation of a LC-MS/MS method for homocysteine thiolactone in plasma and evaluation of its stability in plasma samples

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 944, Issue , 2014, Pages 49-54

  Arora, Beauty ^a   Narayanasamy, Angayarkanni ^b   Nirmal, Jayabalan ^a   Halder, Nabanita ^a   Patnaik, Santosh ^a   Ravi, Alok K ^a   Velpandian, Thirumurthy ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b Department of Biochemistry and Cell Biology Sankara Nethralaya ^*  (India)

Author keywords

HILIC; Homocysteine thiolactone; LC MS MS; Plasma; Stability; Validation

Indexed keywords

CONVERGENCE OF NUMERICAL METHODS; FORMIC ACID; PLASMAS;

GRADIENT ELUTION; HILIC; HOMOCYSTEINES; INTERNAL STANDARDS; LC-MS/MS; MULTIPLE-REACTION MONITORING MODES; SENSITIVE METHOD; VALIDATION;

PLASMA STABILITY;

ACETONITRILE; FORMIC ACID; HOMATROPINE; HOMOCYSTEINE THIOLACTONE; ION; WATER;

ACCURACY; ARTICLE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; ELECTROSPRAY; ELUTION; HUMAN; HUMAN EXPERIMENT; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ION MONITORING; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; MULTIPLE REACTION MONITORING; NORMAL HUMAN; PLASMA; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY;

HILIC; HOMOCYSTEINE THIOLACTONE; LC-MS/MS; PLASMA; STABILITY; VALIDATION;

ADULT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; HOMOCYSTEINE; HUMANS; LIMIT OF DETECTION; MALE; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 84897009162     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.11.011     Document Type: Article

References (19)

1. Clarke R., Daly L., Robinson K., Naughten E., Cahalane S., Fowler B., Graham I. N. Engl. J. Med. 1991, 324:1149-1155.
2. Gu W., Lu J., Yang G., Dou J., Mu Y., Meng J., Pan C. Adv. Ther. 2008, 25:914-924.
3. Jakubowski H., Zhang L., Bardeguez A., Aviv A. Circ. Res. 2000, 87:45-51.
4. Barathi S., Angayarkanni N., Pasupathi A., Natarajan S.K., Pukraj R., Dhupper M., Velpandian T., Muralidharan C., Sivashanmugham M. Diabetes Care 2010, 33:2031-2037.
5. Chwatko G., Jakubowski H. Clin. Chem. 2005, 51:408-415.
6. Jakubowski H. Anal. Biochem. 2002, 308:112-119.
7. Daneshvar P., Yazdanpanah M., Cuthbert C., Cole D.E. Rapid Commun. Mass Spectrom. 2003, 17:358-362.
8. FDA Guidance for Industry Bioanalytical Method Validation 2001.
9. Nirmal J., Velpandian T., Singh S.B., Biswas N.R., Thavaraj V., Azad R., Ghose S. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2011, 879:585-590.
10. Lam S., Boselli L. Biomed. Chromatogr. 1986, 1:177-179.
11. Baernstein H.D. J. Biol. Chem. 1934, 106:451-456.
12. Jakubowski H. J. Physiol. Pharmacol. 2008, 59(Suppl. 9):155-167.
13. Perla-Kajan J., Twardowski T., Jakubowski H. Amino Acids 2007, 32:561-572.
14. Velpandian T., Nirmal J., Arora B., Ravi A.K., Kotnala A. Anal. Lett. 2012, 45:2367-2376.
15. Jakubowski H. J. Biol. Chem. 1997, 272:1935-1942.
16. Jakubowski H. Homocysteine in Health and Disease 2001, 21-31. Cambridge University Press, UK. R. Carmel, D.W. Jacobsen (Eds.).
17. Jakubowski H. FASEB J. 1999, 13:2277-2283.
18. Jakubowski H. Biomed. Pharmacother. 2001, 55:443-447.
19. Nagata Y., Akino T., Ohno K., Kataoka Y., Ueda T., Sakurai T., Shiroshita K., Yasuda T. Clin. Sci. (Lond.) 1987, 73:105-108.